Click here to switch to the map view.

The map label for this gene is aglR [H]

Identifier: 190894536

GI number: 190894536

Start: 198836

End: 199876

Strand: Reverse

Name: aglR [H]

Synonym: RHECIAT_PC0000198

Alternate gene names: 190894536

Gene position: 199876-198836 (Counterclockwise)

Preceding gene: 190894545

Following gene: 190894535

Centisome position: 18.31

GC content: 61.58

Gene sequence:

>1041_bases
ATGAAAGGGATTCGCCAGCTTGCCGAATCCCTGGATATCTCGATCGGAACGGTCTCCCGCGCGCTGAACGGCAGGCCTGA
AGTCAACGAGGAAACCCGTCTTCGGGTGTTGGCGGCGGCCGAGGAATTCGGCTATGTCGCCAACCAATCGGGGCGGAGCT
TGAGGCAGGGAGAGACCAAGGTCATCGGCCTGATGATCGAATCCAGCGCGGAGGCGGTCGAAAATGCCGACAACTTCTTC
CTCGGCGTCACCAGTGGCTTGCAGAGCGTCTTCGCCCGCCACAAGCTCGATCTCGTCATGCTGCCCTGCCCCAGCGATGA
GGAGCCGCACGAATATTTGAAGCGCATGGTAGCGCGGCGCATCGTCGATGCGATGATCATCTCGAATACGCAGCGCATCG
ACCGTCGCATCGATCTTCTGTCGCGGGCAAAGATTCCGTTCGTTACGGTCGGTCGCAGCCTGTCGGCGAACAATTTCCCA
TGGATCGATCTCGATTTCGAGGGCGTAGCCGAGCGTGCCGTCGAGCGCTTGGTCGCGCGCGGTCACCGCCGGATCGCAAT
TACCGCGCCGTCGAGCGAGGTCAATCTCGGCTATGTCTTTGTCGAGAGCTATCGCCGTACGCTCGAGCGGCACGGTATCG
CCTTTGATCCGTCGCTCGTCATCCGCGTCAAATCGAGCGAACATGGCGGCTACCAAGCGGGCCATGAACTGCTGCTGTTG
GCGGAACGGCCGACGGCCGTGATCTTGATCTACGAGCTGATGGCGATCGGCCTTTACCGCCGCCTGATGGAATCGGGCGT
CATGCCCGGCCGTGATCTCGCGGTGATCGGCTTCCGCGATGCTCCGCGCGCCCGGTTTCTGCAGCCGCCGCTCAGCTGTT
TCCGCATGTCGCTGTACGATCTTGGCGTGGCGCTCGGCCAGATGCTGCTCGCCCACATGCCGGCCTATCGAGAATTCTAT
TCCAATGACGGTGGCAACATCATCTGGCCGCTCGAACTGGTGGCAGGGGAAAGCGACGCGTTTCAGCTGACGGAGGCCTG
A

Upstream 100 bases:

>100_bases
GACAGGCACTCCGTAAACGTTTACGACTGTATGCGAAAACATTTTGCGGTGTCAATAGAGGCCAATTGTGAAATTACGGG
CGGGAGGAAAACCACAACAG

Downstream 100 bases:

>100_bases
AGGTTGCCGGCTTCGGCCTCCCCTGCGAGCACGGCAGAGGATATGATGGCTGGGTGACAAAAAATGTCTCGCGGAGCCCG
ATCATTCGAATTTAATCTCT

Product: putative LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKGIRQLAESLDISIGTVSRALNGRPEVNEETRLRVLAAAEEFGYVANQSGRSLRQGETKVIGLMIESSAEAVENADNFF
LGVTSGLQSVFARHKLDLVMLPCPSDEEPHEYLKRMVARRIVDAMIISNTQRIDRRIDLLSRAKIPFVTVGRSLSANNFP
WIDLDFEGVAERAVERLVARGHRRIAITAPSSEVNLGYVFVESYRRTLERHGIAFDPSLVIRVKSSEHGGYQAGHELLLL
AERPTAVILIYELMAIGLYRRLMESGVMPGRDLAVIGFRDAPRARFLQPPLSCFRMSLYDLGVALGQMLLAHMPAYREFY
SNDGGNIIWPLELVAGESDAFQLTEA

Sequences:

>Translated_346_residues
MKGIRQLAESLDISIGTVSRALNGRPEVNEETRLRVLAAAEEFGYVANQSGRSLRQGETKVIGLMIESSAEAVENADNFF
LGVTSGLQSVFARHKLDLVMLPCPSDEEPHEYLKRMVARRIVDAMIISNTQRIDRRIDLLSRAKIPFVTVGRSLSANNFP
WIDLDFEGVAERAVERLVARGHRRIAITAPSSEVNLGYVFVESYRRTLERHGIAFDPSLVIRVKSSEHGGYQAGHELLLL
AERPTAVILIYELMAIGLYRRLMESGVMPGRDLAVIGFRDAPRARFLQPPLSCFRMSLYDLGVALGQMLLAHMPAYREFY
SNDGGNIIWPLELVAGESDAFQLTEA
>Mature_346_residues
MKGIRQLAESLDISIGTVSRALNGRPEVNEETRLRVLAAAEEFGYVANQSGRSLRQGETKVIGLMIESSAEAVENADNFF
LGVTSGLQSVFARHKLDLVMLPCPSDEEPHEYLKRMVARRIVDAMIISNTQRIDRRIDLLSRAKIPFVTVGRSLSANNFP
WIDLDFEGVAERAVERLVARGHRRIAITAPSSEVNLGYVFVESYRRTLERHGIAFDPSLVIRVKSSEHGGYQAGHELLLL
AERPTAVILIYELMAIGLYRRLMESGVMPGRDLAVIGFRDAPRARFLQPPLSCFRMSLYDLGVALGQMLLAHMPAYREFY
SNDGGNIIWPLELVAGESDAFQLTEA

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=311, Percent_Identity=26.0450160771704, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787948, Length=321, Percent_Identity=27.1028037383178, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789068, Length=306, Percent_Identity=26.1437908496732, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=27.5167785234899, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790194, Length=303, Percent_Identity=24.4224422442244, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787906, Length=344, Percent_Identity=24.1279069767442, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787580, Length=308, Percent_Identity=21.7532467532468, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788474, Length=295, Percent_Identity=24.406779661017, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789456, Length=302, Percent_Identity=23.841059602649, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786540, Length=299, Percent_Identity=25.752508361204, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38589; Mature: 38589

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIRQLAESLDISIGTVSRALNGRPEVNEETRLRVLAAAEEFGYVANQSGRSLRQGETK
CCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHEEEEEHHHHHCCHHCCCCCHHHCCCCE
VIGLMIESSAEAVENADNFFLGVTSGLQSVFARHKLDLVMLPCPSDEEPHEYLKRMVARR
EEEEEEECCHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHH
IVDAMIISNTQRIDRRIDLLSRAKIPFVTVGRSLSANNFPWIDLDFEGVAERAVERLVAR
HHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHC
GHRRIAITAPSSEVNLGYVFVESYRRTLERHGIAFDPSLVIRVKSSEHGGYQAGHELLLL
CCCEEEEECCCCCCEEEHEEHHHHHHHHHHCCCEECCEEEEEEECCCCCCCCCCCEEEEE
AERPTAVILIYELMAIGLYRRLMESGVMPGRDLAVIGFRDAPRARFLQPPLSCFRMSLYD
ECCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHH
LGVALGQMLLAHMPAYREFYSNDGGNIIWPLELVAGESDAFQLTEA
HHHHHHHHHHHHCHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCC
>Mature Secondary Structure
MKGIRQLAESLDISIGTVSRALNGRPEVNEETRLRVLAAAEEFGYVANQSGRSLRQGETK
CCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHEEEEEHHHHHCCHHCCCCCHHHCCCCE
VIGLMIESSAEAVENADNFFLGVTSGLQSVFARHKLDLVMLPCPSDEEPHEYLKRMVARR
EEEEEEECCHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHH
IVDAMIISNTQRIDRRIDLLSRAKIPFVTVGRSLSANNFPWIDLDFEGVAERAVERLVAR
HHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHC
GHRRIAITAPSSEVNLGYVFVESYRRTLERHGIAFDPSLVIRVKSSEHGGYQAGHELLLL
CCCEEEEECCCCCCEEEHEEHHHHHHHHHHCCCEECCEEEEEEECCCCCCCCCCCEEEEE
AERPTAVILIYELMAIGLYRRLMESGVMPGRDLAVIGFRDAPRARFLQPPLSCFRMSLYD
ECCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHH
LGVALGQMLLAHMPAYREFYSNDGGNIIWPLELVAGESDAFQLTEA
HHHHHHHHHHHHCHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]