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The map label for this gene is qor [C]

Identifier: 190894356

GI number: 190894356

Start: 14613

End: 15581

Strand: Reverse

Name: qor [C]

Synonym: RHECIAT_PC0000016

Alternate gene names: 190894356

Gene position: 15581-14613 (Counterclockwise)

Preceding gene: 190894360

Following gene: 190894354

Centisome position: 1.43

GC content: 65.43

Gene sequence:

>969_bases
ATGCAATATCAGGCGGTGGTGCGAAAATTCGGTCCGGTCCAAGAGGTCGTCGGGATCGAGCGGACGCCGCTGCCGGCGCT
GCGGCGCGATCAGGTGCGGGTGCGGCTGCTGGCGCGCTCGATCAATCCTTCCGATATCATCACCATTTCGGGCGCCTATG
CCGGCCGCACGACCCTGCCCTTTATTCCGGGCTTCGAGGCCTTCGGCGTGGTCGAAGCCTGCGGTGAAGAGGTCTATGGA
CTGCCGCCGGGGACGCGCGTACTGCCGGTGCGCAGCGCCGGCGGCTGGCAGGAGTTCAAGGACACCGACCCGAACTGGTG
CCTGCGCGTGCCGGAGACGCTTTCCGATTTCGAGGCGGCGACCAGCTACGTCAACCCGATGACGGCCTGGCTGATGCTGC
ATATCAAGATCGGGCTGAGACCGGGCATGCGCATCGCCGTCAATGCCGCCGCCTCCTCGATCGGATCGATCCTGATCGGC
CTCGCGAATGCCGTTGGTGTCGAGCCGGTGGCGATCGTCCGCAGCGAAGAATCCCGCCAGAGCCTGCGCGGCCGGCTCGA
GACGGTCATCGTCGACAGGGAGGACAGCGACCTGGCAGCCGGGCTCGCCGGCCGGCATGGCCTGGACGCCGTGCTCGACT
GCGTCGGCGGCCCGCGCGCCTCTGTTCTTGCCGATGCGCTGAAGCCCGGCGGCCATTTCGTGCACTATGGGCTGCTCTCC
GGTGAAAGCATCCCGAATTCCTTCTGGGCCACCCATTCCGACATCACCTTTTCCTTCTGCCATCTTCGGGAATGGGTCCA
TTCCGAAACCATCGACAATGTCCAGCGCGCTTATTCAGAGGTGGCCGCGCAGATCGCCGCAAAGGTGATCGCAACCGAGG
TGCGGGAGGTGTTTCCCTTGGAAAGGATCGGCGAGGCGCTGCAAGCCGCCCTTCCCTTCCGGACTGGCGGCAAGGTGCTG
CTCGCTTGA

Upstream 100 bases:

>100_bases
GCATCGAGACCCGGAACGATGCTAAAGGCCTGTCGTCAACGCTCATTCGATCACCCAAAATTGGTGGGCTGTTCTAACCG
CTGTTCTCAGGGGGATGCAA

Downstream 100 bases:

>100_bases
GGGGCCACGCTCCAACCTTGCTTCTTGCGCCCAGCCCCGGGTGGCCGACCTCGCCCTTCGAGGCCCCTGCGGGGCACCTC
AGGATGAGGTCGGAGAGAGG

Product: putative zinc-dependent oxidoreductase

Products: NADP(+); Semiquinone. [C]

Alternate protein names: Oxidoreductase; Quinone Oxidoreductase; NADPHQuinone Reductase; NAD(P)H Quinone Oxidoreductase PIG3 Family; Zinc-Containing Alcohol Dehydrogenase Superfamily Protein; Alcohol Dehydrogenase Zinc-Containing; Dehydrogenase; Trans-2-Enoyl-CoA Reductase; Alcohol Dehydrogenase GroES Domain-Containing Protein; Zn-Dependent Oxidoreductase; NADPH Quinone Oxidoreductase; Zinc-Containing Alcohol Dehydrogenase; Oxidoreductase Zinc-Containing Alcohol Dehydrogenase; Alcohol Dehydrogenase GroES Domain Protein; Zinc-Dependent Oxidoreductase Protein; PIG3 Family NAD(P)H Quinone Oxidoreductase; Zn-Dependent Alcohol Dehydrogenase; Zn-Dependent Oxidoreductase NADphQuinone Reductase; Oxidoreductase Protein; NADPH2Quinone Reductase; Oxidoreductase/Dehydrogenase; NADP-Dependent Quinone Oxidoreductase; Oxydoreductase Protein Zinc-Containing; Dehydrogenase/Oxidoreductase; Alcohol Dehydrogenase Superfamily Zinc-Containing Protein; Acyl Transferase; Polyketide Synthase

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MQYQAVVRKFGPVQEVVGIERTPLPALRRDQVRVRLLARSINPSDIITISGAYAGRTTLPFIPGFEAFGVVEACGEEVYG
LPPGTRVLPVRSAGGWQEFKDTDPNWCLRVPETLSDFEAATSYVNPMTAWLMLHIKIGLRPGMRIAVNAAASSIGSILIG
LANAVGVEPVAIVRSEESRQSLRGRLETVIVDREDSDLAAGLAGRHGLDAVLDCVGGPRASVLADALKPGGHFVHYGLLS
GESIPNSFWATHSDITFSFCHLREWVHSETIDNVQRAYSEVAAQIAAKVIATEVREVFPLERIGEALQAALPFRTGGKVL
LA

Sequences:

>Translated_322_residues
MQYQAVVRKFGPVQEVVGIERTPLPALRRDQVRVRLLARSINPSDIITISGAYAGRTTLPFIPGFEAFGVVEACGEEVYG
LPPGTRVLPVRSAGGWQEFKDTDPNWCLRVPETLSDFEAATSYVNPMTAWLMLHIKIGLRPGMRIAVNAAASSIGSILIG
LANAVGVEPVAIVRSEESRQSLRGRLETVIVDREDSDLAAGLAGRHGLDAVLDCVGGPRASVLADALKPGGHFVHYGLLS
GESIPNSFWATHSDITFSFCHLREWVHSETIDNVQRAYSEVAAQIAAKVIATEVREVFPLERIGEALQAALPFRTGGKVL
LA
>Mature_322_residues
MQYQAVVRKFGPVQEVVGIERTPLPALRRDQVRVRLLARSINPSDIITISGAYAGRTTLPFIPGFEAFGVVEACGEEVYG
LPPGTRVLPVRSAGGWQEFKDTDPNWCLRVPETLSDFEAATSYVNPMTAWLMLHIKIGLRPGMRIAVNAAASSIGSILIG
LANAVGVEPVAIVRSEESRQSLRGRLETVIVDREDSDLAAGLAGRHGLDAVLDCVGGPRASVLADALKPGGHFVHYGLLS
GESIPNSFWATHSDITFSFCHLREWVHSETIDNVQRAYSEVAAQIAAKVIATEVREVFPLERIGEALQAALPFRTGGKVL
LA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI67078404, Length=316, Percent_Identity=29.746835443038, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI67078406, Length=295, Percent_Identity=29.1525423728814, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI18379349, Length=308, Percent_Identity=28.2467532467532, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI24308257, Length=263, Percent_Identity=26.9961977186312, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI194239674, Length=289, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI13236495, Length=289, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=291, Percent_Identity=31.2714776632302, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17556000, Length=340, Percent_Identity=28.8235294117647, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17507255, Length=173, Percent_Identity=32.9479768786127, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45550423, Length=331, Percent_Identity=31.1178247734139, Blast_Score=110, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.5.5 [C]

Molecular weight: Translated: 34788; Mature: 34788

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYQAVVRKFGPVQEVVGIERTPLPALRRDQVRVRLLARSINPSDIITISGAYAGRTTLP
CCHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
FIPGFEAFGVVEACGEEVYGLPPGTRVLPVRSAGGWQEFKDTDPNWCLRVPETLSDFEAA
CCCCHHHHHHHHHHCHHHCCCCCCCEEEEECCCCCCHHHCCCCCCEEEECCHHHHHHHHH
TSYVNPMTAWLMLHIKIGLRPGMRIAVNAAASSIGSILIGLANAVGVEPVAIVRSEESRQ
HHHHHHHHHHHHHHEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHH
SLRGRLETVIVDREDSDLAAGLAGRHGLDAVLDCVGGPRASVLADALKPGGHFVHYGLLS
HHHHHEEEEEEECCCCHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEC
GESIPNSFWATHSDITFSFCHLREWVHSETIDNVQRAYSEVAAQIAAKVIATEVREVFPL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ERIGEALQAALPFRTGGKVLLA
HHHHHHHHHHCCCCCCCCEEEC
>Mature Secondary Structure
MQYQAVVRKFGPVQEVVGIERTPLPALRRDQVRVRLLARSINPSDIITISGAYAGRTTLP
CCHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
FIPGFEAFGVVEACGEEVYGLPPGTRVLPVRSAGGWQEFKDTDPNWCLRVPETLSDFEAA
CCCCHHHHHHHHHHCHHHCCCCCCCEEEEECCCCCCHHHCCCCCCEEEECCHHHHHHHHH
TSYVNPMTAWLMLHIKIGLRPGMRIAVNAAASSIGSILIGLANAVGVEPVAIVRSEESRQ
HHHHHHHHHHHHHHEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHH
SLRGRLETVIVDREDSDLAAGLAGRHGLDAVLDCVGGPRASVLADALKPGGHFVHYGLLS
HHHHHEEEEEEECCCCHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEC
GESIPNSFWATHSDITFSFCHLREWVHSETIDNVQRAYSEVAAQIAAKVIATEVREVFPL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ERIGEALQAALPFRTGGKVLLA
HHHHHHHHHHCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.017 {9,10-phenanthrenequinone}} 0.0153 {2,6-dichlorophenolindophenol}} 0.013 {2,6-dichlorophenolindophenol}} 0.26 {1,4-naphthoquinone}} 0.065 {1,4-benzoquinone}} 0.007 {NADPH}} 0.0069 {NADPH}} 0.0024 {1,2-naphthoquinone}} [C]

Substrates: NADPH; Quinone [C]

Specific reaction: NADPH + Quinone = NADP(+) + Semiquinone. [C]

General reaction: Oxidation; Reduction [C]

Inhibitor: 2, 3-Dimercaptopropanol; 2, 5-Dichloro-3, 6-dihydroxy -1, 4-benzoquinone; 4-Hydroxy coumarin; 5, 5'-Dithiobis (2-nitrobenzoate); ADP; Cibacronblue3GA; Coumarin; Cu2+; Dicoumarol warfarin, coumarin; Dithiothreitol preincubation with 9, 10-phenanthrenequino

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA