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The map label for this gene is engA [H]

Identifier: 190571288

GI number: 190571288

Start: 958793

End: 960118

Strand: Direct

Name: engA [H]

Synonym: WPa_0891

Alternate gene names: 190571288

Gene position: 958793-960118 (Clockwise)

Preceding gene: 190571279

Following gene: 190571289

Centisome position: 64.68

GC content: 37.1

Gene sequence:

>1326_bases
ATGCTGAAAATAGTCATAATAGGCCTTCCAAATGCAGGCAAGTCAACTCTATTTAATAGGCTGGTGGGAAGAAAAGCAGC
GGTAGTTAGTGACATTCCAGGAGTAACGAGAGATAGGCGTGAAGGAATTGGAAGAATTAGTGATTTAGAGTTTAAAGTTA
TAGATACAGGAGGATGGAATGACCAAACCAGTTTTTCACTACAAGTTATTGAACAAATAGAGTTTTCTTTGTCGAGTGCA
GATGTAGTTTTCTTTCTTGTTGATGCAAAAGTGCAAAACGAGCAGAACAAAGAGTTTGCAAAGTGGCTGAAGAGAAAAAC
AAATAAACCTGTAATACTAATAGCAAACAAATGTGAAAGTCATAAATCGGAAAATGTTGATTATTTGCAGTTTTTCAATT
TCATAGGTCCGGTATACATCTCAGCCGAACATAATCTTGGCATGGTTGATCTTTATGATGCATTAGCTGGTGTGATTGAA
GGTCTTAGCGAAGGCACTGAGCTGCCTGAAAGTGAGTCCATTAGACTGAGGATTGCAATCATCGGTCGCCCAAACGTTGG
AAAATCAACTTTTTTAAACAGTTTACTTGCAGAAAATAGACTAATAGTAAGCTCAGAACCCGGTACCACGCGTGACTCTG
TGGATATTTCATACGACCATAATGGGAAATTAATCACTCTCATCGACACTGCGGGAATCCGCAGAAAGGCAAATGTTGTT
GATAACTTAGAATCAAGATTTGTTGAAAAAAGTATAGAGTCAATAAAGCGCTCTCATGTAGTGATTTTAATGTTAGATTC
CTTGCTTGGCATTGAGCAGCAGGATTTATCAATTGCTGAAGCTGCAATTAAAGGGGGGAAGGGAATTATCATTGTTTTAA
ATAAGTGGGATTTAATAGGTAAGGATGACAGAAGTAAGTTAATAAAATTTGTCAAACAACAGGAAGTGACTCGGTTATTT
TTGGAAGTGCCAACTGTAACAATTTCTGCATTGAAAGGTATGCGCTGTGGTGATGTGATAGATAAGTGTCTTGAAGTGAG
TGAATCCTTAAACAAGAAGATCAGCACTGCAAAACTGAATAATTGGCTAATAGATGCTGTGGAAAAACATTCTCACCCAC
TTATAAAAGGTAGAGAGATTAAAATGAAGTATATTGCTCAAATTGGCACCAAACCTCCAGCTTTTTCTTTGGTATGCAAC
GTCCCGGAAAGTGTTGATGAGAGTTATAAACGTTATTTGACTAATGGTCTTAGAAAAAACTTCTTTGTTGAAGGTGTACC
AGTTAGATTGCTTTTGAAAAAGAATAAAAACCCCTATGTAAAGTAG

Upstream 100 bases:

>100_bases
AATATCCTAATTTTAGGATAGGTATATAATCTATCAAGTCAATAGTTAAATTAAAAAATTTTGATTATAATTTACTATTT
ATAAAATACGCTCTTAAACT

Downstream 100 bases:

>100_bases
ATAATCTTGTTTTACTAATAATATACTTTTTTATCTTAGTAATATTATTAATAAGTAAATAATATTACTTAAATAAGTAG
TTGATAAATTAATATTATAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MLKIVIIGLPNAGKSTLFNRLVGRKAAVVSDIPGVTRDRREGIGRISDLEFKVIDTGGWNDQTSFSLQVIEQIEFSLSSA
DVVFFLVDAKVQNEQNKEFAKWLKRKTNKPVILIANKCESHKSENVDYLQFFNFIGPVYISAEHNLGMVDLYDALAGVIE
GLSEGTELPESESIRLRIAIIGRPNVGKSTFLNSLLAENRLIVSSEPGTTRDSVDISYDHNGKLITLIDTAGIRRKANVV
DNLESRFVEKSIESIKRSHVVILMLDSLLGIEQQDLSIAEAAIKGGKGIIIVLNKWDLIGKDDRSKLIKFVKQQEVTRLF
LEVPTVTISALKGMRCGDVIDKCLEVSESLNKKISTAKLNNWLIDAVEKHSHPLIKGREIKMKYIAQIGTKPPAFSLVCN
VPESVDESYKRYLTNGLRKNFFVEGVPVRLLLKKNKNPYVK

Sequences:

>Translated_441_residues
MLKIVIIGLPNAGKSTLFNRLVGRKAAVVSDIPGVTRDRREGIGRISDLEFKVIDTGGWNDQTSFSLQVIEQIEFSLSSA
DVVFFLVDAKVQNEQNKEFAKWLKRKTNKPVILIANKCESHKSENVDYLQFFNFIGPVYISAEHNLGMVDLYDALAGVIE
GLSEGTELPESESIRLRIAIIGRPNVGKSTFLNSLLAENRLIVSSEPGTTRDSVDISYDHNGKLITLIDTAGIRRKANVV
DNLESRFVEKSIESIKRSHVVILMLDSLLGIEQQDLSIAEAAIKGGKGIIIVLNKWDLIGKDDRSKLIKFVKQQEVTRLF
LEVPTVTISALKGMRCGDVIDKCLEVSESLNKKISTAKLNNWLIDAVEKHSHPLIKGREIKMKYIAQIGTKPPAFSLVCN
VPESVDESYKRYLTNGLRKNFFVEGVPVRLLLKKNKNPYVK
>Mature_441_residues
MLKIVIIGLPNAGKSTLFNRLVGRKAAVVSDIPGVTRDRREGIGRISDLEFKVIDTGGWNDQTSFSLQVIEQIEFSLSSA
DVVFFLVDAKVQNEQNKEFAKWLKRKTNKPVILIANKCESHKSENVDYLQFFNFIGPVYISAEHNLGMVDLYDALAGVIE
GLSEGTELPESESIRLRIAIIGRPNVGKSTFLNSLLAENRLIVSSEPGTTRDSVDISYDHNGKLITLIDTAGIRRKANVV
DNLESRFVEKSIESIKRSHVVILMLDSLLGIEQQDLSIAEAAIKGGKGIIIVLNKWDLIGKDDRSKLIKFVKQQEVTRLF
LEVPTVTISALKGMRCGDVIDKCLEVSESLNKKISTAKLNNWLIDAVEKHSHPLIKGREIKMKYIAQIGTKPPAFSLVCN
VPESVDESYKRYLTNGLRKNFFVEGVPVRLLLKKNKNPYVK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=35.6223175965665, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI2367268, Length=123, Percent_Identity=36.5853658536585, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=91, Percent_Identity=40.6593406593407, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=159, Percent_Identity=34.5911949685535, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49248; Mature: 49248

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIVIIGLPNAGKSTLFNRLVGRKAAVVSDIPGVTRDRREGIGRISDLEFKVIDTGGWN
CEEEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEECCCCC
DQTSFSLQVIEQIEFSLSSADVVFFLVDAKVQNEQNKEFAKWLKRKTNKPVILIANKCES
CCCCHHHHHHHHHHHCCCCCCEEEEEEECHHCCCCCHHHHHHHHHCCCCCEEEEECCCCC
HKSENVDYLQFFNFIGPVYISAEHNLGMVDLYDALAGVIEGLSEGTELPESESIRLRIAI
CCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IGRPNVGKSTFLNSLLAENRLIVSSEPGTTRDSVDISYDHNGKLITLIDTAGIRRKANVV
EECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHH
DNLESRFVEKSIESIKRSHVVILMLDSLLGIEQQDLSIAEAAIKGGKGIIIVLNKWDLIG
HHHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCC
KDDRSKLIKFVKQQEVTRLFLEVPTVTISALKGMRCGDVIDKCLEVSESLNKKISTAKLN
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NWLIDAVEKHSHPLIKGREIKMKYIAQIGTKPPAFSLVCNVPESVDESYKRYLTNGLRKN
HHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHC
FFVEGVPVRLLLKKNKNPYVK
CEECCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MLKIVIIGLPNAGKSTLFNRLVGRKAAVVSDIPGVTRDRREGIGRISDLEFKVIDTGGWN
CEEEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEECCCCC
DQTSFSLQVIEQIEFSLSSADVVFFLVDAKVQNEQNKEFAKWLKRKTNKPVILIANKCES
CCCCHHHHHHHHHHHCCCCCCEEEEEEECHHCCCCCHHHHHHHHHCCCCCEEEEECCCCC
HKSENVDYLQFFNFIGPVYISAEHNLGMVDLYDALAGVIEGLSEGTELPESESIRLRIAI
CCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IGRPNVGKSTFLNSLLAENRLIVSSEPGTTRDSVDISYDHNGKLITLIDTAGIRRKANVV
EECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHH
DNLESRFVEKSIESIKRSHVVILMLDSLLGIEQQDLSIAEAAIKGGKGIIIVLNKWDLIG
HHHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCC
KDDRSKLIKFVKQQEVTRLFLEVPTVTISALKGMRCGDVIDKCLEVSESLNKKISTAKLN
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NWLIDAVEKHSHPLIKGREIKMKYIAQIGTKPPAFSLVCNVPESVDESYKRYLTNGLRKN
HHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHC
FFVEGVPVRLLLKKNKNPYVK
CEECCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA