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The map label for this gene is purQ [H]

Identifier: 190571279

GI number: 190571279

Start: 947625

End: 948422

Strand: Direct

Name: purQ [H]

Synonym: WPa_0880

Alternate gene names: 190571279

Gene position: 947625-948422 (Clockwise)

Preceding gene: 190571278

Following gene: 190571288

Centisome position: 63.92

GC content: 34.59

Gene sequence:

>798_bases
ATGAAAATTACAATCCTATCTGGTTATGGCTTAAATTGCGAAAAAGAAACTGCATTTGCATTTATGGAATGCAGCAGAAA
GCTTGGTATTAATAATATTGAAGTAAAAATCGTTCACATTAATGATATTATAGATAATCCAAGTGAACTGAAATTAAGCA
ATATACTTGCAATTCCAGGAGGTTTTTCCTATGGTGATGATACTGGTGCTGGTAATGCATTTGCTTTACGTATAAAAAAC
AACTTGTTAGACGAATTTCAAAATTTCTTATCTCAGGATAAGCTTATTATAGGGATATGTAATGGTTGCCAGATATTAGT
AAAATTAGTTCCAGAATTCTCTAATCTAGCTTTAACCTCTAATGATATAGGTAATTACCAATGTCGTTGGATTAGAGTGA
GAGTTAATCCGCAGAGTAGTTCTGTTTGGCTACGGGGCCTGAGTGAGCTATATCTTCCTGTTGCTCATGGAGAAGGCAGG
TTTTTTATGGATCAAGATATTTTAAATCAATTGATTGAAAATAATTCCGTTGCACTGCGTTACGTTGATAAAAATGGTGA
CTATGCAAATTTACAATTTCCTTACAATCCAAACGGATCTATATACGACCTGGCAGCTTTGTCAGACAAAAGTGGTAGAG
TTTTAGCTTTAATGCCTCACCCAGAGAGAGGAATATTTTTTACTCAGCAGGACAACTGGCCTCTTGAAAAAGAAAAATGT
AAACGTTCAGGAGTGGCTATGCCAAAATATGGTGATGGAATGCTCATATTTGAGAATGCACTAAAATATTTTGCGTAA

Upstream 100 bases:

>100_bases
TTGAGCTTGCTGCCATTGCAATTATAGCTTTATTGTTAATGCTATTTGCTTTGAATTTAATAGCAAATTTTGTAAAAAGA
AAGTTCGAGTTTTTTGATTC

Downstream 100 bases:

>100_bases
CGTTACATACAACAAGCCATAAAAAGTTACTTTCCTTGTTATGACAATAAATCCTTATCTTTGATCTGCAGAGTAGCTTT
CTCTAACGTTAGGGATATAA

Product: phosphoribosylformylglycinamidine synthase I, putative

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKITILSGYGLNCEKETAFAFMECSRKLGINNIEVKIVHINDIIDNPSELKLSNILAIPGGFSYGDDTGAGNAFALRIKN
NLLDEFQNFLSQDKLIIGICNGCQILVKLVPEFSNLALTSNDIGNYQCRWIRVRVNPQSSSVWLRGLSELYLPVAHGEGR
FFMDQDILNQLIENNSVALRYVDKNGDYANLQFPYNPNGSIYDLAALSDKSGRVLALMPHPERGIFFTQQDNWPLEKEKC
KRSGVAMPKYGDGMLIFENALKYFA

Sequences:

>Translated_265_residues
MKITILSGYGLNCEKETAFAFMECSRKLGINNIEVKIVHINDIIDNPSELKLSNILAIPGGFSYGDDTGAGNAFALRIKN
NLLDEFQNFLSQDKLIIGICNGCQILVKLVPEFSNLALTSNDIGNYQCRWIRVRVNPQSSSVWLRGLSELYLPVAHGEGR
FFMDQDILNQLIENNSVALRYVDKNGDYANLQFPYNPNGSIYDLAALSDKSGRVLALMPHPERGIFFTQQDNWPLEKEKC
KRSGVAMPKYGDGMLIFENALKYFA
>Mature_265_residues
MKITILSGYGLNCEKETAFAFMECSRKLGINNIEVKIVHINDIIDNPSELKLSNILAIPGGFSYGDDTGAGNAFALRIKN
NLLDEFQNFLSQDKLIIGICNGCQILVKLVPEFSNLALTSNDIGNYQCRWIRVRVNPQSSSVWLRGLSELYLPVAHGEGR
FFMDQDILNQLIENNSVALRYVDKNGDYANLQFPYNPNGSIYDLAALSDKSGRVLALMPHPERGIFFTQQDNWPLEKEKC
KRSGVAMPKYGDGMLIFENALKYFA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=248, Percent_Identity=33.4677419354839, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI48994899, Length=272, Percent_Identity=36.0294117647059, Blast_Score=124, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17553022, Length=247, Percent_Identity=31.1740890688259, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321498, Length=286, Percent_Identity=31.8181818181818, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24582111, Length=249, Percent_Identity=36.5461847389558, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24582109, Length=249, Percent_Identity=36.5461847389558, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17137292, Length=249, Percent_Identity=36.5461847389558, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 29744; Mature: 29744

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITILSGYGLNCEKETAFAFMECSRKLGINNIEVKIVHINDIIDNPSELKLSNILAIPG
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCEEEEEEEECCC
GFSYGDDTGAGNAFALRIKNNLLDEFQNFLSQDKLIIGICNGCQILVKLVPEFSNLALTS
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHCEEEEC
NDIGNYQCRWIRVRVNPQSSSVWLRGLSELYLPVAHGEGRFFMDQDILNQLIENNSVALR
CCCCCEEEEEEEEEECCCCCHHHHHCHHHHEEEEECCCCCEEECHHHHHHHHCCCCEEEE
YVDKNGDYANLQFPYNPNGSIYDLAALSDKSGRVLALMPHPERGIFFTQQDNWPLEKEKC
EEECCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCHHHH
KRSGVAMPKYGDGMLIFENALKYFA
HHCCCCCCCCCCCEEEEEHHHHHCC
>Mature Secondary Structure
MKITILSGYGLNCEKETAFAFMECSRKLGINNIEVKIVHINDIIDNPSELKLSNILAIPG
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCEEEEEEEECCC
GFSYGDDTGAGNAFALRIKNNLLDEFQNFLSQDKLIIGICNGCQILVKLVPEFSNLALTS
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHCEEEEC
NDIGNYQCRWIRVRVNPQSSSVWLRGLSELYLPVAHGEGRFFMDQDILNQLIENNSVALR
CCCCCEEEEEEEEEECCCCCHHHHHCHHHHEEEEECCCCCEEECHHHHHHHHCCCCEEEE
YVDKNGDYANLQFPYNPNGSIYDLAALSDKSGRVLALMPHPERGIFFTQQDNWPLEKEKC
EEECCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCHHHH
KRSGVAMPKYGDGMLIFENALKYFA
HHCCCCCCCCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA