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The map label for this gene is mraY [H]

Identifier: 190571268

GI number: 190571268

Start: 939764

End: 940744

Strand: Direct

Name: mraY [H]

Synonym: WPa_0869

Alternate gene names: 190571268

Gene position: 939764-940744 (Clockwise)

Preceding gene: 190571264

Following gene: 190571269

Centisome position: 63.39

GC content: 32.11

Gene sequence:

>981_bases
GTGATCTCAGCTACAAAGACGTTTTTTATCTCATTTATTTTTGGGTTTATTCTCTTTCCCTATTTTATAAAACTTCTAAA
AAAGATAAGTAAAGATGGACAACCAATCAGATCATATGGACCAGAAAGTCATTTAATAACAAAAAAGAATATACCACCTA
TGGGTGGAATAATAATACTAACTTCTGCTTTATTACCAATCCTGCTTTGGACTCAATTAACACCAGAAATTTCATTGCTG
GTATTTATAACTCTATTTTTTGCTCTACTTGGATTTATTGATGACTATTTAAAATTGAAGACAAATCACCACCGAGGTTT
AAGTGCAAAAACCAAAATACTTATTCAGTTTGTCGTTACTCTGGTCTGTATGTTTATACTTAAGCTACAATCTGCTGAAG
GTTTTACAAAAATTTCTCTATTTAGAGAAGTAGCAATCGACCTTGGCTATCTATATCTTCCGTTTGCTGCATTTGTTATT
GTTGGCTCTTCTAATGCTGTGAATCTTACAGATGGCCTAGATGGCCTTGCTGCAACTCAAGCCATTACTTCCTTTGCTTT
TTTGGGGCTAATTGCATACATCACTCAGACAGATGTAAACATTACTTTATTCTGCATTGCATTTATAGGAGCTATTTTAA
GTTTCTTGTGGTTTAACACACATCCAGCAAAAATATTTATGGGTGATGTTGGAAGCCTATCAATCGGTGCAGCTTTAGGA
CTCACTAGTGTTCTAATTAAAAAAGAAATGCTTTTTGCCGTTATTGGAATAATCTTTGTAATAGAGACTTTATCTGTGAT
TATTCAGGTATCATATTTTAAATATACAAAATTTAGATATGGAGCAGGAAGAAGAATTTTCCTTATGACACCAATACATC
ATCACTTTGAAAAGAAAGGGTGGTCAGAAAATACAATAGTTATAAAATTTTGGATAATTTCTATTGCTTGTTCGATTTTT
GCTTTAACTTTCTTATTATAG

Upstream 100 bases:

>100_bases
ATAACTAAATTTACTCCAAATAAAATAAGCTGATAAAAAGGTATAAATTGAGATTAGGTAAAGCTTTTGGTATAATATCT
AGTTAATTTTGAATAGGCAG

Downstream 100 bases:

>100_bases
GAATTATGAAATATCCAGACTTTTCATTAGAAAATACATTATCAGGAATTATAGCAGGAGTAGATGAAGTTGGAAGAGGT
CCGCTTGCCGGTCCAGTGAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MISATKTFFISFIFGFILFPYFIKLLKKISKDGQPIRSYGPESHLITKKNIPPMGGIIILTSALLPILLWTQLTPEISLL
VFITLFFALLGFIDDYLKLKTNHHRGLSAKTKILIQFVVTLVCMFILKLQSAEGFTKISLFREVAIDLGYLYLPFAAFVI
VGSSNAVNLTDGLDGLAATQAITSFAFLGLIAYITQTDVNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSIGAALG
LTSVLIKKEMLFAVIGIIFVIETLSVIIQVSYFKYTKFRYGAGRRIFLMTPIHHHFEKKGWSENTIVIKFWIISIACSIF
ALTFLL

Sequences:

>Translated_326_residues
MISATKTFFISFIFGFILFPYFIKLLKKISKDGQPIRSYGPESHLITKKNIPPMGGIIILTSALLPILLWTQLTPEISLL
VFITLFFALLGFIDDYLKLKTNHHRGLSAKTKILIQFVVTLVCMFILKLQSAEGFTKISLFREVAIDLGYLYLPFAAFVI
VGSSNAVNLTDGLDGLAATQAITSFAFLGLIAYITQTDVNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSIGAALG
LTSVLIKKEMLFAVIGIIFVIETLSVIIQVSYFKYTKFRYGAGRRIFLMTPIHHHFEKKGWSENTIVIKFWIISIACSIF
ALTFLL
>Mature_326_residues
MISATKTFFISFIFGFILFPYFIKLLKKISKDGQPIRSYGPESHLITKKNIPPMGGIIILTSALLPILLWTQLTPEISLL
VFITLFFALLGFIDDYLKLKTNHHRGLSAKTKILIQFVVTLVCMFILKLQSAEGFTKISLFREVAIDLGYLYLPFAAFVI
VGSSNAVNLTDGLDGLAATQAITSFAFLGLIAYITQTDVNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSIGAALG
LTSVLIKKEMLFAVIGIIFVIETLSVIIQVSYFKYTKFRYGAGRRIFLMTPIHHHFEKKGWSENTIVIKFWIISIACSIF
ALTFLL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=343, Percent_Identity=39.9416909620991, Blast_Score=232, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 36397; Mature: 36397

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISATKTFFISFIFGFILFPYFIKLLKKISKDGQPIRSYGPESHLITKKNIPPMGGIIIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEECCCCCCCCHHHHH
TSALLPILLWTQLTPEISLLVFITLFFALLGFIDDYLKLKTNHHRGLSAKTKILIQFVVT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LVCMFILKLQSAEGFTKISLFREVAIDLGYLYLPFAAFVIVGSSNAVNLTDGLDGLAATQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEECCCCCCHHHHHH
AITSFAFLGLIAYITQTDVNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSIGAALG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
LTSVLIKKEMLFAVIGIIFVIETLSVIIQVSYFKYTKFRYGAGRRIFLMTPIHHHFEKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCHHHHHHHCC
WSENTIVIKFWIISIACSIFALTFLL
CCCCEEEEHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MISATKTFFISFIFGFILFPYFIKLLKKISKDGQPIRSYGPESHLITKKNIPPMGGIIIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEECCCCCCCCHHHHH
TSALLPILLWTQLTPEISLLVFITLFFALLGFIDDYLKLKTNHHRGLSAKTKILIQFVVT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LVCMFILKLQSAEGFTKISLFREVAIDLGYLYLPFAAFVIVGSSNAVNLTDGLDGLAATQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEECCCCCCHHHHHH
AITSFAFLGLIAYITQTDVNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSIGAALG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
LTSVLIKKEMLFAVIGIIFVIETLSVIIQVSYFKYTKFRYGAGRRIFLMTPIHHHFEKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCHHHHHHHCC
WSENTIVIKFWIISIACSIFALTFLL
CCCCEEEEHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA