Click here to switch to the map view.

The map label for this gene is sugE [H]

Identifier: 190571240

GI number: 190571240

Start: 917575

End: 917892

Strand: Reverse

Name: sugE [H]

Synonym: WPa_0840

Alternate gene names: 190571240

Gene position: 917892-917575 (Counterclockwise)

Preceding gene: 190571241

Following gene: 190571238

Centisome position: 61.92

GC content: 37.11

Gene sequence:

>318_bases
ATGGCTTGGGTGTATTTGCTATTAGCTGGTTTGGTTGAAATAATATGGACCACAGCACTGAAATATAGCAATGGCTTTAC
TCGTGTTATACCTGTAGTAATTATTTTAGTTAGCGGTTCTGTGAGTCTTTACTGGCTATCGTTAGCAATGAAGTCTATTC
CTCTTGGAACATCTTATGCAGTTTGGACTGGTATAGGCTCTATAGGTGCAGCGATAATAGGAATAATGTTTTTTAATGAC
CCAGTAAATTTTGGGCGTTTATTTTCCCTTGCTTTGGTAGTGCTGGGTATCATAGGATTAAAAGTATTTTCCAATTAG

Upstream 100 bases:

>100_bases
ATTAGAAATTGGATGTGATAGTATTACTAAAGCATGCGAAATGCTAAGTTAACTTTTTAATATTCCTATATATAATATTT
CAGTAAGATAGAGTTGATTT

Downstream 100 bases:

>100_bases
GAAAAGTTAAGTACGTCTATTTTACCACCTCAGGACTTTCTACTAAAGTTGCTTTGGATTTTTCAGTTCTCGAAGAGGGC
ATTCCTATTGATTTAGAAAG

Product: sugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MAWVYLLLAGLVEIIWTTALKYSNGFTRVIPVVIILVSGSVSLYWLSLAMKSIPLGTSYAVWTGIGSIGAAIIGIMFFND
PVNFGRLFSLALVVLGIIGLKVFSN

Sequences:

>Translated_105_residues
MAWVYLLLAGLVEIIWTTALKYSNGFTRVIPVVIILVSGSVSLYWLSLAMKSIPLGTSYAVWTGIGSIGAAIIGIMFFND
PVNFGRLFSLALVVLGIIGLKVFSN
>Mature_104_residues
AWVYLLLAGLVEIIWTTALKYSNGFTRVIPVVIILVSGSVSLYWLSLAMKSIPLGTSYAVWTGIGSIGAAIIGIMFFNDP
VNFGRLFSLALVVLGIIGLKVFSN

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=105, Percent_Identity=53.3333333333333, Blast_Score=113, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11312; Mature: 11181

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWVYLLLAGLVEIIWTTALKYSNGFTRVIPVVIILVSGSVSLYWLSLAMKSIPLGTSYA
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHH
VWTGIGSIGAAIIGIMFFNDPVNFGRLFSLALVVLGIIGLKVFSN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWVYLLLAGLVEIIWTTALKYSNGFTRVIPVVIILVSGSVSLYWLSLAMKSIPLGTSYA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHH
VWTGIGSIGAAIIGIMFFNDPVNFGRLFSLALVVLGIIGLKVFSN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]