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The map label for this gene is pdhS [H]

Identifier: 190571186

GI number: 190571186

Start: 859964

End: 861391

Strand: Direct

Name: pdhS [H]

Synonym: WPa_0784

Alternate gene names: 190571186

Gene position: 859964-861391 (Clockwise)

Preceding gene: 190571184

Following gene: 190571187

Centisome position: 58.01

GC content: 28.71

Gene sequence:

>1428_bases
ATGTATAAATTAAGTAAATTAATTTTTACTACACTAAAAACAAATAGATATACAAAAATTATCTCGCTATTCTTATTAAT
TTTTGTGGTTTTATTGGGCACAATATACCGCAGTTATTCATTAAAGAATAATTTTCTTTCTTTTTACCGTAATTCAAATG
CAAACTTAAAAGATCTATTGGAAAATAGTATAATAAAAAAATATCATTATTTACTAATAGAAAAACATCATATTAAATAT
AACAGTTTTGATTACATAAACCAGTTGGTAAAATTGCGTGCTGAATTGTTACAATCAGTAAGCAAAGTAAGAAATTTTAG
CTTAATACTGTATGATCAAAATGCCAGAGTGATTTTCAGTAATTTTAATACTCAAGGTCATGACTATGAGCAGTTGCTTA
CAAATGATGAAATTGATAAATTGCTAAGCAATCAAGAAATATTTTACGCTACAGGAAATACATTAACTTCTACTTTCCCT
ATATTTCATGAAGATGACATTAAGCCTTCATTTTTTTTGAAGATCATTCAAAGCTATAATGACTCTTATATTATGGTATA
TAGTCTATTTTCAATATTAATGGGCTTATTACTGGTTATCTTAATACTAATAATGCTTTATTTGCACTTTTCCAATACCC
AAATGCTAGCCAAGCAGCATAAAACTAATATTGAATTACAAAGGGTTAAAGAGGCATTAGAGCAAGAAAATGCAAATAAG
ATAAAATTTTTTGCAAGTGTTACACATGAGTTGCGTACACCTCTTAATGCTATTATTGGATTTGCAAAGTTGATCAAAAA
TGAAACTTTAGGTTCGGTAGATCACTCTAAATACAAGGAATACGTAGACGATATATATAATGCTGGTACACATTTACTTG
CTTTGATTAATGATGTGCTCGATTTTTCTAAAGCTGAATCAAGTAGTTTAACAGTAGAGAAAGTGAAGTTTAATCTGAAT
AAGATAATAGATTCGTGCTTAAAAATGTTATCACCTAAACTAAAAGAAACAGGGATTAGTTTAAAGAAAGAGATATCTGA
TAAACAATTATTAGTTATCGCCGATCCCAAAAGAATGAAGCAAGTTATAATAAATTTGTTATCAAATGCTATCAAGTTCA
CTCCTCAAGGTGGTTTAATAAGAATGATTATTAAAGAGAATATAGAAAAAAATTTATTAACTATTGAGTTTCATGATAAT
GGAATAGGGATAATGCAGCAGGACATATATAAAGTTATGTCCGTTTTTGGCCAAGCAGATTCGGGATATAGAAACGAAGG
CACAGGTATCGGATTACCTCTAAGCAAGAAATTAGTAGAGTTAATGGGTGGGACTTTCAACATTCAAAGTGAAGCAAAAC
TTGGTACTACGATAACATTGAGCTTCTTTTATGAAGAGCAAACATGTGAAAAGTTGATTGATTTTTAG

Upstream 100 bases:

>100_bases
AGGAGAATAAACTGGCAAGATAGGAGAAATTGTCATAAAAGTATGATATGCTAATTTTTTATTAATACCATAAAAGACGT
TATTTCACAATGAGAAGAAT

Downstream 100 bases:

>100_bases
TAAAATATATTTGATATTGCACTTTTATATCTAGTACATTCCTAAGTCATACTGACGTGATACCTCTTGGCTAATAATAA
GTAGCGGAATGTAAGTAAAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MYKLSKLIFTTLKTNRYTKIISLFLLIFVVLLGTIYRSYSLKNNFLSFYRNSNANLKDLLENSIIKKYHYLLIEKHHIKY
NSFDYINQLVKLRAELLQSVSKVRNFSLILYDQNARVIFSNFNTQGHDYEQLLTNDEIDKLLSNQEIFYATGNTLTSTFP
IFHEDDIKPSFFLKIIQSYNDSYIMVYSLFSILMGLLLVILILIMLYLHFSNTQMLAKQHKTNIELQRVKEALEQENANK
IKFFASVTHELRTPLNAIIGFAKLIKNETLGSVDHSKYKEYVDDIYNAGTHLLALINDVLDFSKAESSSLTVEKVKFNLN
KIIDSCLKMLSPKLKETGISLKKEISDKQLLVIADPKRMKQVIINLLSNAIKFTPQGGLIRMIIKENIEKNLLTIEFHDN
GIGIMQQDIYKVMSVFGQADSGYRNEGTGIGLPLSKKLVELMGGTFNIQSEAKLGTTITLSFFYEEQTCEKLIDF

Sequences:

>Translated_475_residues
MYKLSKLIFTTLKTNRYTKIISLFLLIFVVLLGTIYRSYSLKNNFLSFYRNSNANLKDLLENSIIKKYHYLLIEKHHIKY
NSFDYINQLVKLRAELLQSVSKVRNFSLILYDQNARVIFSNFNTQGHDYEQLLTNDEIDKLLSNQEIFYATGNTLTSTFP
IFHEDDIKPSFFLKIIQSYNDSYIMVYSLFSILMGLLLVILILIMLYLHFSNTQMLAKQHKTNIELQRVKEALEQENANK
IKFFASVTHELRTPLNAIIGFAKLIKNETLGSVDHSKYKEYVDDIYNAGTHLLALINDVLDFSKAESSSLTVEKVKFNLN
KIIDSCLKMLSPKLKETGISLKKEISDKQLLVIADPKRMKQVIINLLSNAIKFTPQGGLIRMIIKENIEKNLLTIEFHDN
GIGIMQQDIYKVMSVFGQADSGYRNEGTGIGLPLSKKLVELMGGTFNIQSEAKLGTTITLSFFYEEQTCEKLIDF
>Mature_475_residues
MYKLSKLIFTTLKTNRYTKIISLFLLIFVVLLGTIYRSYSLKNNFLSFYRNSNANLKDLLENSIIKKYHYLLIEKHHIKY
NSFDYINQLVKLRAELLQSVSKVRNFSLILYDQNARVIFSNFNTQGHDYEQLLTNDEIDKLLSNQEIFYATGNTLTSTFP
IFHEDDIKPSFFLKIIQSYNDSYIMVYSLFSILMGLLLVILILIMLYLHFSNTQMLAKQHKTNIELQRVKEALEQENANK
IKFFASVTHELRTPLNAIIGFAKLIKNETLGSVDHSKYKEYVDDIYNAGTHLLALINDVLDFSKAESSSLTVEKVKFNLN
KIIDSCLKMLSPKLKETGISLKKEISDKQLLVIADPKRMKQVIINLLSNAIKFTPQGGLIRMIIKENIEKNLLTIEFHDN
GIGIMQQDIYKVMSVFGQADSGYRNEGTGIGLPLSKKLVELMGGTFNIQSEAKLGTTITLSFFYEEQTCEKLIDF

Specific function: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn r

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with divK (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=36.6255144032922, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=35.4166666666667, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=31.8367346938775, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=30.1652892561983, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=29.2576419213974, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=24.7863247863248, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786783, Length=320, Percent_Identity=22.8125, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=27.9166666666667, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=400, Percent_Identity=21.75, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=25.2252252252252, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786600, Length=262, Percent_Identity=25.5725190839695, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=24.3697478991597, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788279, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54666; Mature: 54666

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLSKLIFTTLKTNRYTKIISLFLLIFVVLLGTIYRSYSLKNNFLSFYRNSNANLKDLL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ENSIIKKYHYLLIEKHHIKYNSFDYINQLVKLRAELLQSVSKVRNFSLILYDQNARVIFS
HHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEE
NFNTQGHDYEQLLTNDEIDKLLSNQEIFYATGNTLTSTFPIFHEDDIKPSFFLKIIQSYN
CCCCCCCCHHHHHCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCC
DSYIMVYSLFSILMGLLLVILILIMLYLHFSNTQMLAKQHKTNIELQRVKEALEQENANK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCH
IKFFASVTHELRTPLNAIIGFAKLIKNETLGSVDHSKYKEYVDDIYNAGTHLLALINDVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHH
DFSKAESSSLTVEKVKFNLNKIIDSCLKMLSPKLKETGISLKKEISDKQLLVIADPKRMK
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCCEEEEEECHHHHH
QVIINLLSNAIKFTPQGGLIRMIIKENIEKNLLTIEFHDNGIGIMQQDIYKVMSVFGQAD
HHHHHHHHHHHEECCCCCEEEHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
SGYRNEGTGIGLPLSKKLVELMGGTFNIQSEAKLGTTITLSFFYEEQTCEKLIDF
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHCC
>Mature Secondary Structure
MYKLSKLIFTTLKTNRYTKIISLFLLIFVVLLGTIYRSYSLKNNFLSFYRNSNANLKDLL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ENSIIKKYHYLLIEKHHIKYNSFDYINQLVKLRAELLQSVSKVRNFSLILYDQNARVIFS
HHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEE
NFNTQGHDYEQLLTNDEIDKLLSNQEIFYATGNTLTSTFPIFHEDDIKPSFFLKIIQSYN
CCCCCCCCHHHHHCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCC
DSYIMVYSLFSILMGLLLVILILIMLYLHFSNTQMLAKQHKTNIELQRVKEALEQENANK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCH
IKFFASVTHELRTPLNAIIGFAKLIKNETLGSVDHSKYKEYVDDIYNAGTHLLALINDVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHH
DFSKAESSSLTVEKVKFNLNKIIDSCLKMLSPKLKETGISLKKEISDKQLLVIADPKRMK
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCCEEEEEECHHHHH
QVIINLLSNAIKFTPQGGLIRMIIKENIEKNLLTIEFHDNGIGIMQQDIYKVMSVFGQAD
HHHHHHHHHHHEECCCCCEEEHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
SGYRNEGTGIGLPLSKKLVELMGGTFNIQSEAKLGTTITLSFFYEEQTCEKLIDF
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA