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The map label for this gene is htpG [H]

Identifier: 190571174

GI number: 190571174

Start: 844512

End: 846428

Strand: Direct

Name: htpG [H]

Synonym: WPa_0772

Alternate gene names: 190571174

Gene position: 844512-846428 (Clockwise)

Preceding gene: 190571173

Following gene: 190571175

Centisome position: 56.97

GC content: 36.15

Gene sequence:

>1917_bases
ATGGAGCTCAAAATGCACAACATACAAGAAACTGAAAGTTTAAAATTTGACGCTGAAGTAGGCAAAGTACTAAATATAGT
AATTCATTCACTTTATACTAATAAGGATATTTTCTTGCGTGAGTTAATATCAAATGCATCAGATGCATGTGATAAATTGC
GCTATGAATCACAATTAAATGCTGATTTATTAGATTCAAGTGATGAGTTGAAGATTACTATTAGCTCCAGTAAAGATAAG
AATGAGCTGTATATAACCGATAATGGAATTGGAATGAACAGACAGGATTTAATAGATAATCTTGGCACGATTGCAAGTTC
TGGTACGCAAAAATTCTTGGATGCAATTAAGAATAATAAAGATTCGAGCCAAGCTGTAGAGCTGATTGGAAAGTTTGGTG
TTGGTTTTTATTCAAGCTTCATGGTTGCTTCAGAAGTTATAGTAGAATCAAGGAAAGCCGGAGAAGAAGAGTCTTGGGTG
TGGAAATCTAAAGGAGATGGAGAGTATTCAATCAGCAAATTAGATGGTCAAATCTCTCGTGGCACAAAAATTACGCTCAT
CATGCGTCCTGAAGAAAGCGAATTTTTAGACAAATTCCGTATTGAAAACATCGTTACTACTTACTCTGACCACATAAATT
TTCCCGTTGAGTTTGTAAATGAAGAAGGAAAAAGTGAAAAATTAAATAGCAAAGCTGCAATTTGGACTAAGCCAAAAAAT
GACGTTACTCCAGAAGAGCACAACGACTTCTTCCGTGGTGTTGCACATGTGGGCGGTGAGCCTTGGATGATATTTCATAA
TAAAAATGAAGGTGCAATAGAGTATACGAACTTGCTTTATGTTCCTTCTATCAAGCCTTTTGATTTATTTCATCCAGATA
GACGCTGCTCTGTAAAATTGTATGTAAATAAAGTGTTTATCACTGAAGATAATGTGCAGATTATACCGCAGTACTTGCGT
TTTTTGAAAGGTGTGGTTGATTCACCGGATTTGCCTCTCAATATCAGCAGAGAAACACTGCAGAACAATCGCGTTGTTGA
GCAGATTAGGAAATCTTTAACTAAGCGCATAATATCAGAGCTCGGCAAAAAAGCAAAAGAGAATTTAGAGGAATATACAA
AATTCTGGGGCAATTTTGGTGCGGTGTTAAAAGAAGGTCTTTGCGAAGCTATGCCAACTGATGAAAGAGAAGCATTGCTT
TCCATTTGCAGATTTCATAGCACCAGTGATGGTAAGCTAGTTAGCATTGATGATTATATAAGCAGAATGAAGCCTGAACA
GGAACATATCTACTATCTCACAGGTAATAGTCTCGATTCAGTAAAAAACAGTCCACAACTTGAAGGATTCGTCAGCAAAG
GATTGGAAGTGCTTCTATTTGTTGATCCAGTTGATGATTTCTGGACTAGCGTGATTCATGAATATAAAGATCAAAAATTT
AAGTCTGTGACCCGCGCTGATGTTGATTTAGAAAAATTTTCTTCAGAAGAAGGCAAGAAAGATGAAGAAAATAAATCAGA
TGAAAACAAAAGCGAAGAAAACGCGGATTCTATACTCGAATACTTCACCAAGGTTCTTGGAAGCTTAGTAAAAAGTGTAA
AGATCTCTAAGAAATTAACCGATAGTCCTGTGTGTCTAGCAGTTGATGAAGGAACTATGGACCTCCGTATGGAGCGTTTT
TTACGTGAACAGAAGCAGCTAAATTACCGCACGCCAAAAGTACTTGAAATTAACATTAAGCATCCTTTGATAAGAAACAT
AATGGAATCTCACGCTAAAAATGGTGAAAATCCAACACTTGGAGATATGATTTACTTATTGTTCTATCAAGCTTGTATAG
TGGAAGGTGAAGAGATGGAAGACGTAAGTCTATTTGCTAAAAGGCTCAATAACTTGCTTGGCAAAATTTCTATTTAA

Upstream 100 bases:

>100_bases
TTTAGCATTGGAACCATAAGTTGGCCCACATAAATTTTAGCATGTGTGACCTTGAAAGATCGCAGTGCAATACTTAAATT
ATTAGAGTAGTAGGCTAATA

Downstream 100 bases:

>100_bases
TGCTATACTTAGTTTAGCTAATAATTAGGGGGTAAAACATGGGGTGGAATTTACTTGGTGGGCTCATGCCGCCAGCAGTA
GATACTGCAGAAGAAAGGGA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MELKMHNIQETESLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLNADLLDSSDELKITISSSKDK
NELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNNKDSSQAVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWV
WKSKGDGEYSISKLDGQISRGTKITLIMRPEESEFLDKFRIENIVTTYSDHINFPVEFVNEEGKSEKLNSKAAIWTKPKN
DVTPEEHNDFFRGVAHVGGEPWMIFHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKLYVNKVFITEDNVQIIPQYLR
FLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRIISELGKKAKENLEEYTKFWGNFGAVLKEGLCEAMPTDEREALL
SICRFHSTSDGKLVSIDDYISRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKF
KSVTRADVDLEKFSSEEGKKDEENKSDENKSEENADSILEYFTKVLGSLVKSVKISKKLTDSPVCLAVDEGTMDLRMERF
LREQKQLNYRTPKVLEINIKHPLIRNIMESHAKNGENPTLGDMIYLLFYQACIVEGEEMEDVSLFAKRLNNLLGKISI

Sequences:

>Translated_638_residues
MELKMHNIQETESLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLNADLLDSSDELKITISSSKDK
NELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNNKDSSQAVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWV
WKSKGDGEYSISKLDGQISRGTKITLIMRPEESEFLDKFRIENIVTTYSDHINFPVEFVNEEGKSEKLNSKAAIWTKPKN
DVTPEEHNDFFRGVAHVGGEPWMIFHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKLYVNKVFITEDNVQIIPQYLR
FLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRIISELGKKAKENLEEYTKFWGNFGAVLKEGLCEAMPTDEREALL
SICRFHSTSDGKLVSIDDYISRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKF
KSVTRADVDLEKFSSEEGKKDEENKSDENKSEENADSILEYFTKVLGSLVKSVKISKKLTDSPVCLAVDEGTMDLRMERF
LREQKQLNYRTPKVLEINIKHPLIRNIMESHAKNGENPTLGDMIYLLFYQACIVEGEEMEDVSLFAKRLNNLLGKISI
>Mature_638_residues
MELKMHNIQETESLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLNADLLDSSDELKITISSSKDK
NELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNNKDSSQAVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWV
WKSKGDGEYSISKLDGQISRGTKITLIMRPEESEFLDKFRIENIVTTYSDHINFPVEFVNEEGKSEKLNSKAAIWTKPKN
DVTPEEHNDFFRGVAHVGGEPWMIFHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKLYVNKVFITEDNVQIIPQYLR
FLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRIISELGKKAKENLEEYTKFWGNFGAVLKEGLCEAMPTDEREALL
SICRFHSTSDGKLVSIDDYISRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKF
KSVTRADVDLEKFSSEEGKKDEENKSDENKSEENADSILEYFTKVLGSLVKSVKISKKLTDSPVCLAVDEGTMDLRMERF
LREQKQLNYRTPKVLEINIKHPLIRNIMESHAKNGENPTLGDMIYLLFYQACIVEGEEMEDVSLFAKRLNNLLGKISI

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=688, Percent_Identity=32.703488372093, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI155722983, Length=643, Percent_Identity=33.7480559875583, Blast_Score=358, Evalue=7e-99,
Organism=Homo sapiens, GI154146191, Length=416, Percent_Identity=32.9326923076923, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI153792590, Length=416, Percent_Identity=32.9326923076923, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI20149594, Length=416, Percent_Identity=32.2115384615385, Blast_Score=214, Evalue=2e-55,
Organism=Escherichia coli, GI1786679, Length=634, Percent_Identity=41.6403785488959, Blast_Score=501, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17559162, Length=676, Percent_Identity=34.0236686390533, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17542208, Length=676, Percent_Identity=33.5798816568047, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI115535205, Length=658, Percent_Identity=32.9787234042553, Blast_Score=328, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI115535167, Length=432, Percent_Identity=37.037037037037, Blast_Score=271, Evalue=8e-73,
Organism=Saccharomyces cerevisiae, GI6323840, Length=683, Percent_Identity=33.2357247437775, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6325016, Length=418, Percent_Identity=33.2535885167464, Blast_Score=243, Evalue=6e-65,
Organism=Drosophila melanogaster, GI21357739, Length=690, Percent_Identity=32.7536231884058, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24586016, Length=641, Percent_Identity=31.98127925117, Blast_Score=304, Evalue=1e-82,
Organism=Drosophila melanogaster, GI17647529, Length=416, Percent_Identity=34.375, Blast_Score=249, Evalue=3e-66,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72807; Mature: 72807

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKMHNIQETESLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLN
CCCCCCCCCHHHCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
ADLLDSSDELKITISSSKDKNELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNNK
HHHCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
DSSQAVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWVWKSKGDGEYSISKLDGQISR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEHHHHCCCCCC
GTKITLIMRPEESEFLDKFRIENIVTTYSDHINFPVEFVNEEGKSEKLNSKAAIWTKPKN
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHCCCCCEEEECCCC
DVTPEEHNDFFRGVAHVGGEPWMIFHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKL
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEE
YVNKVFITEDNVQIIPQYLRFLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRIISE
EEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
LGKKAKENLEEYTKFWGNFGAVLKEGLCEAMPTDEREALLSICRFHSTSDGKLVSIDDYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHH
SRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKF
HHCCCCCCEEEEEECCCHHHHCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHH
KSVTRADVDLEKFSSEEGKKDEENKSDENKSEENADSILEYFTKVLGSLVKSVKISKKLT
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DSPVCLAVDEGTMDLRMERFLREQKQLNYRTPKVLEINIKHPLIRNIMESHAKNGENPTL
CCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCH
GDMIYLLFYQACIVEGEEMEDVSLFAKRLNNLLGKISI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELKMHNIQETESLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLN
CCCCCCCCCHHHCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
ADLLDSSDELKITISSSKDKNELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNNK
HHHCCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
DSSQAVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWVWKSKGDGEYSISKLDGQISR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEHHHHCCCCCC
GTKITLIMRPEESEFLDKFRIENIVTTYSDHINFPVEFVNEEGKSEKLNSKAAIWTKPKN
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHCCCCCEEEECCCC
DVTPEEHNDFFRGVAHVGGEPWMIFHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKL
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEE
YVNKVFITEDNVQIIPQYLRFLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRIISE
EEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
LGKKAKENLEEYTKFWGNFGAVLKEGLCEAMPTDEREALLSICRFHSTSDGKLVSIDDYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHH
SRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKF
HHCCCCCCEEEEEECCCHHHHCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHH
KSVTRADVDLEKFSSEEGKKDEENKSDENKSEENADSILEYFTKVLGSLVKSVKISKKLT
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DSPVCLAVDEGTMDLRMERFLREQKQLNYRTPKVLEINIKHPLIRNIMESHAKNGENPTL
CCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCH
GDMIYLLFYQACIVEGEEMEDVSLFAKRLNNLLGKISI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA