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The map label for this gene is aprE [H]

Identifier: 190570554

GI number: 190570554

Start: 81059

End: 82570

Strand: Reverse

Name: aprE [H]

Synonym: WPa_0084

Alternate gene names: 190570554

Gene position: 82570-81059 (Counterclockwise)

Preceding gene: 190570555

Following gene: 190570553

Centisome position: 5.57

GC content: 35.05

Gene sequence:

>1512_bases
ATGAGTAAGTTAAAAAAGCTTAGTGCTGGACTTTCTTTGACAGGCCTAATTGGTAGTGATGATATAGATATGCAAAGGGC
AGGAAATAGAAAGAAGAAATATCAATTTTTGGATAAGACGTTCGCATGGATTGATGCGATGATAAATTTTATTTTTAAAC
GTGAGAGTAATAACGTAAATGAAGTCCTAAAAGTCACATGGGGACCACTATTTTTTGGTTTAGTGGTGATATTCATCTTT
TTTGGAATAGGTGGTATTTGGTCAGCTATAGCTCCAATTGACGGAGCAGTGCATGCAAGTGGAGAAGTTATTGTCTCTTC
AAATAGAAAAATAGTGCAACACTTGGGTGGGGGAATAATAAGCAAAATTTTAGTAAAAGAAGGTCAAGCAGTTAAAAAAG
ATGAGCCTTTAGTTTTATTAAGTGATGTTAACGAAAAGGCAAATTTGAGTATAATTAAAGAAAAACTCTTATCACTTTTG
GCAACTGAAGCAAGACTTATTGCAATCAGGGGAGACTTAGATACGCTAGAATTTTCTGATGAGGTTAAAAGATTATCTAA
CGATGAACTTGTAAATAAAGCGATAAAGAATCAGGTAAAGTTGTTCAACTCTCAGAGAAAGAGTATATTAGGAAAAACTG
ACATACTGCAACAACGTATAAAGCAGTTAAATGATGAATTAGCAGGGCTAAATTTTCAACTAAATGCAGCCCATAAGCAA
TATGACTTGATAACTGAGGAGTTAGAAACAAAAAGACAATTACTTGATAGTGGACATATAAGCAAACCACACATTTTAGC
TTTAGAAAAACAGTTTGCTGAAATTGAGGGTAGAGTTGGACATTACCGTTCTGCAATATCTCAAGTACAGCAAAAGATTG
GAGAAAATGAGTTAGAGATTATAAATGTGAAGAATGATGCTCAAGAAAGAGCAAATGCTGAGCTTAAGGAAGTTAATACA
TCTATTGCAGACTTAAAAGAGAGGCTGATGGTTGCTGAAGATTCGTTAGCACGTACAATAATTAAATCACCTCAAGATGG
TATAGTTACAGATATAAGATACCACACTGAAGGTGGTGTTATACAATCTGGAGTCCCAATCCTGAGTATAGTACCATCAG
ATGATGATCTAATAATAGATGCTAAAGTTCTAACCAGAAACATAGAAGAGATACTGTCAGCAAAAAAGAAAGATAGCAAT
ATAGTCTCTATCGACGGACTAGAAGGGCTGAAAGTTAAAGTAAGGCTGAGCGCTTATAGTGCACGTCGCTTAAGTTTAAT
TAACGGTATAGTAAACCATATTTCCCCTGATGCTCTTGATGATCCAAGGATGGGGCGTTATTATTCAGTGCGAGTGGTGA
TACCAAAGTCAGAACTTGCTCAATTTAAAAACGTATACCTATATCCTGGTATGCCAGTAGAAGTATATATAGTTACTCAA
TCTCGCACTCTTTTATCGTTCTTGTTTACACCTATAATTGCAACATTCGATAGATCTTTCATAGAGAGATAA

Upstream 100 bases:

>100_bases
GTTTATTCTGATGTTCCGTAGTCTAAGTAAAGTACTTAAGGTATAGATTCTTTGTTTTTGTGTGTTATCCTGGTTAACAA
GAATTCGCAGTAGTATTATA

Downstream 100 bases:

>100_bases
TTTATTTGGCTTTTCTAGAAAATTTGTTTACAGAGTTTGATATGCAAAAAAATTTACACACAAGTAGTGTATTATTTTAT
AATTATTTTCTATAATATGT

Product: secretion protein, HlyD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MSKLKKLSAGLSLTGLIGSDDIDMQRAGNRKKKYQFLDKTFAWIDAMINFIFKRESNNVNEVLKVTWGPLFFGLVVIFIF
FGIGGIWSAIAPIDGAVHASGEVIVSSNRKIVQHLGGGIISKILVKEGQAVKKDEPLVLLSDVNEKANLSIIKEKLLSLL
ATEARLIAIRGDLDTLEFSDEVKRLSNDELVNKAIKNQVKLFNSQRKSILGKTDILQQRIKQLNDELAGLNFQLNAAHKQ
YDLITEELETKRQLLDSGHISKPHILALEKQFAEIEGRVGHYRSAISQVQQKIGENELEIINVKNDAQERANAELKEVNT
SIADLKERLMVAEDSLARTIIKSPQDGIVTDIRYHTEGGVIQSGVPILSIVPSDDDLIIDAKVLTRNIEEILSAKKKDSN
IVSIDGLEGLKVKVRLSAYSARRLSLINGIVNHISPDALDDPRMGRYYSVRVVIPKSELAQFKNVYLYPGMPVEVYIVTQ
SRTLLSFLFTPIIATFDRSFIER

Sequences:

>Translated_503_residues
MSKLKKLSAGLSLTGLIGSDDIDMQRAGNRKKKYQFLDKTFAWIDAMINFIFKRESNNVNEVLKVTWGPLFFGLVVIFIF
FGIGGIWSAIAPIDGAVHASGEVIVSSNRKIVQHLGGGIISKILVKEGQAVKKDEPLVLLSDVNEKANLSIIKEKLLSLL
ATEARLIAIRGDLDTLEFSDEVKRLSNDELVNKAIKNQVKLFNSQRKSILGKTDILQQRIKQLNDELAGLNFQLNAAHKQ
YDLITEELETKRQLLDSGHISKPHILALEKQFAEIEGRVGHYRSAISQVQQKIGENELEIINVKNDAQERANAELKEVNT
SIADLKERLMVAEDSLARTIIKSPQDGIVTDIRYHTEGGVIQSGVPILSIVPSDDDLIIDAKVLTRNIEEILSAKKKDSN
IVSIDGLEGLKVKVRLSAYSARRLSLINGIVNHISPDALDDPRMGRYYSVRVVIPKSELAQFKNVYLYPGMPVEVYIVTQ
SRTLLSFLFTPIIATFDRSFIER
>Mature_502_residues
SKLKKLSAGLSLTGLIGSDDIDMQRAGNRKKKYQFLDKTFAWIDAMINFIFKRESNNVNEVLKVTWGPLFFGLVVIFIFF
GIGGIWSAIAPIDGAVHASGEVIVSSNRKIVQHLGGGIISKILVKEGQAVKKDEPLVLLSDVNEKANLSIIKEKLLSLLA
TEARLIAIRGDLDTLEFSDEVKRLSNDELVNKAIKNQVKLFNSQRKSILGKTDILQQRIKQLNDELAGLNFQLNAAHKQY
DLITEELETKRQLLDSGHISKPHILALEKQFAEIEGRVGHYRSAISQVQQKIGENELEIINVKNDAQERANAELKEVNTS
IADLKERLMVAEDSLARTIIKSPQDGIVTDIRYHTEGGVIQSGVPILSIVPSDDDLIIDAKVLTRNIEEILSAKKKDSNI
VSIDGLEGLKVKVRLSAYSARRLSLINGIVNHISPDALDDPRMGRYYSVRVVIPKSELAQFKNVYLYPGMPVEVYIVTQS
RTLLSFLFTPIIATFDRSFIER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 56151; Mature: 56020

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKKLSAGLSLTGLIGSDDIDMQRAGNRKKKYQFLDKTFAWIDAMINFIFKRESNNVN
CCHHHHHHCCCEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EVLKVTWGPLFFGLVVIFIFFGIGGIWSAIAPIDGAVHASGEVIVSSNRKIVQHLGGGII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEECCHHHHHHHCCHHH
SKILVKEGQAVKKDEPLVLLSDVNEKANLSIIKEKLLSLLATEARLIAIRGDLDTLEFSD
HHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
EVKRLSNDELVNKAIKNQVKLFNSQRKSILGKTDILQQRIKQLNDELAGLNFQLNAAHKQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCHHH
YDLITEELETKRQLLDSGHISKPHILALEKQFAEIEGRVGHYRSAISQVQQKIGENELEI
HHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEE
INVKNDAQERANAELKEVNTSIADLKERLMVAEDSLARTIIKSPQDGIVTDIRYHTEGGV
EEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCE
IQSGVPILSIVPSDDDLIIDAKVLTRNIEEILSAKKKDSNIVSIDGLEGLKVKVRLSAYS
EECCCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEHHH
ARRLSLINGIVNHISPDALDDPRMGRYYSVRVVIPKSELAQFKNVYLYPGMPVEVYIVTQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECHHHHHHHCCEEECCCCCEEEEEEEC
SRTLLSFLFTPIIATFDRSFIER
CHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLKKLSAGLSLTGLIGSDDIDMQRAGNRKKKYQFLDKTFAWIDAMINFIFKRESNNVN
CHHHHHHCCCEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EVLKVTWGPLFFGLVVIFIFFGIGGIWSAIAPIDGAVHASGEVIVSSNRKIVQHLGGGII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEECCHHHHHHHCCHHH
SKILVKEGQAVKKDEPLVLLSDVNEKANLSIIKEKLLSLLATEARLIAIRGDLDTLEFSD
HHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
EVKRLSNDELVNKAIKNQVKLFNSQRKSILGKTDILQQRIKQLNDELAGLNFQLNAAHKQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCHHH
YDLITEELETKRQLLDSGHISKPHILALEKQFAEIEGRVGHYRSAISQVQQKIGENELEI
HHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEE
INVKNDAQERANAELKEVNTSIADLKERLMVAEDSLARTIIKSPQDGIVTDIRYHTEGGV
EEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCE
IQSGVPILSIVPSDDDLIIDAKVLTRNIEEILSAKKKDSNIVSIDGLEGLKVKVRLSAYS
EECCCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEHHH
ARRLSLINGIVNHISPDALDDPRMGRYYSVRVVIPKSELAQFKNVYLYPGMPVEVYIVTQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECHHHHHHHCCEEECCCCCEEEEEEEC
SRTLLSFLFTPIIATFDRSFIER
CHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]