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The map label for this gene is 189499233

Identifier: 189499233

GI number: 189499233

Start: 244891

End: 246090

Strand: Direct

Name: 189499233

Synonym: Cphamn1_0253

Alternate gene names: NA

Gene position: 244891-246090 (Clockwise)

Preceding gene: 189499231

Following gene: 189499234

Centisome position: 8.95

GC content: 48.25

Gene sequence:

>1200_bases
ATGCGTTTGATTCTGATGACCGGAAAAGGAGGCGTAGGAAAGACCTCGATGGCGGCGGCTACGGGACTCAAGTGTGCTGA
AATGGGATATAAGACACTGGTGCTGAGTACAGATCCCGCACACTCTCTTGCCGACAGTTTTGCTGTAGAGCTTGGGCATC
AGCCCAAAGAGGTATGTCAAAATCTGTGGGGCGCCGAGCTTGATGTTCTTGAGGAACTTGAACAGAACTGGGGTTCTGTC
AAGCGATACATTACCGAAGTATTGCAGGCCCGCGGTCTTGAAGGCGTTCAGGCGGAAGAGCTCGCTATTCTTCCGGGATC
TGATGAGATTTTCGGCCTTGTCAGGGTTTTCCGGCATTTCAAGGAAGGGAATTATGATGTGTTGATCATAGATTCCGCTC
CTACAGGAACAGCGCTCCGGTTACTGAGTATTCCTGAAGTTGCCGGTTGGTACATGCGCCGTTTCTACAAGCCTCTGGAG
AAAGTCGCGGTAACACTCCGGCCAATAGTCGAGCCGTTATTCAGGCCGATTGCGGGATTTTCCCTGCCTGACAAGGAGAT
GATGGACGTACCGTATGATTTTTATCAGAAAATCGAGAAGCTTGGGGAAATTCTGATGGATAACGCCGTGACATCGGTAC
GGCTTGTCACCAATCCCGAGAAGATGGTGCTCAACGAGTCTCTCAGGGCTCATGCCTACCTCAGCCTTTACGATATTTCT
ACAGACCTTATTATCGCCAACAGGATCATTCCCGATGAGGTGACCGATCCCTATTTCCAGTACTGGAAAGAAAATCAGAA
AATATATCGAGCGGAGATTCATGAGAATTTCAAGCCTCTGCCTGTCAAAGAGGTCCCGTTGTATTCACGGGAGATTTGTG
GTCTCAAGACGCTCGATACACTGAAAGATCTGCTTTATGGTGACGAAGATCCTTCGCAGGTATATTATAAAGAGAAGACG
ATGCGGGTTGAGCAGGTCAAGAACGGTTATACGCTTGAGATTGCGTTGCCGGGGATTCAGAAAGACCGGATAGAGATCAG
CAAGAAAGGTGACGAACTGAATATACGTATTGGCAATCACCGTCGTAATCTTGTGCTGCCACAGGCTCTTGCAACGCTGA
AGACCGCAGGTGCGGAAATGGAAGATGAATTACTGAAGATCTCTTTCGAAGAGATAAATGTCAGAAAAAAAGGAAAATAG

Upstream 100 bases:

>100_bases
GAATTATCGTAGGGCTGCGGTAAACTATTGTCTTCTCGATGTGGTTAAGTAGTTGACGGTGTATCTGTCACGTATTGAAA
CACATAAACGGGAATAGAGT

Downstream 100 bases:

>100_bases
AGCGGATAAAACAGGTTTGTTCTCCTTAAGAGGTTGTTTTTATTGATTGTTCTTCTTACTATTAACTATAGTTATGGCAT
ATACTTTGTTTTTTGATGCA

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MRLILMTGKGGVGKTSMAAATGLKCAEMGYKTLVLSTDPAHSLADSFAVELGHQPKEVCQNLWGAELDVLEELEQNWGSV
KRYITEVLQARGLEGVQAEELAILPGSDEIFGLVRVFRHFKEGNYDVLIIDSAPTGTALRLLSIPEVAGWYMRRFYKPLE
KVAVTLRPIVEPLFRPIAGFSLPDKEMMDVPYDFYQKIEKLGEILMDNAVTSVRLVTNPEKMVLNESLRAHAYLSLYDIS
TDLIIANRIIPDEVTDPYFQYWKENQKIYRAEIHENFKPLPVKEVPLYSREICGLKTLDTLKDLLYGDEDPSQVYYKEKT
MRVEQVKNGYTLEIALPGIQKDRIEISKKGDELNIRIGNHRRNLVLPQALATLKTAGAEMEDELLKISFEEINVRKKGK

Sequences:

>Translated_399_residues
MRLILMTGKGGVGKTSMAAATGLKCAEMGYKTLVLSTDPAHSLADSFAVELGHQPKEVCQNLWGAELDVLEELEQNWGSV
KRYITEVLQARGLEGVQAEELAILPGSDEIFGLVRVFRHFKEGNYDVLIIDSAPTGTALRLLSIPEVAGWYMRRFYKPLE
KVAVTLRPIVEPLFRPIAGFSLPDKEMMDVPYDFYQKIEKLGEILMDNAVTSVRLVTNPEKMVLNESLRAHAYLSLYDIS
TDLIIANRIIPDEVTDPYFQYWKENQKIYRAEIHENFKPLPVKEVPLYSREICGLKTLDTLKDLLYGDEDPSQVYYKEKT
MRVEQVKNGYTLEIALPGIQKDRIEISKKGDELNIRIGNHRRNLVLPQALATLKTAGAEMEDELLKISFEEINVRKKGK
>Mature_399_residues
MRLILMTGKGGVGKTSMAAATGLKCAEMGYKTLVLSTDPAHSLADSFAVELGHQPKEVCQNLWGAELDVLEELEQNWGSV
KRYITEVLQARGLEGVQAEELAILPGSDEIFGLVRVFRHFKEGNYDVLIIDSAPTGTALRLLSIPEVAGWYMRRFYKPLE
KVAVTLRPIVEPLFRPIAGFSLPDKEMMDVPYDFYQKIEKLGEILMDNAVTSVRLVTNPEKMVLNESLRAHAYLSLYDIS
TDLIIANRIIPDEVTDPYFQYWKENQKIYRAEIHENFKPLPVKEVPLYSREICGLKTLDTLKDLLYGDEDPSQVYYKEKT
MRVEQVKNGYTLEIALPGIQKDRIEISKKGDELNIRIGNHRRNLVLPQALATLKTAGAEMEDELLKISFEEINVRKKGK

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=281, Percent_Identity=24.5551601423488, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17557003, Length=280, Percent_Identity=23.9285714285714, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320103, Length=318, Percent_Identity=25.7861635220126, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24586297, Length=303, Percent_Identity=25.0825082508251, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 45253; Mature: 45253

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLILMTGKGGVGKTSMAAATGLKCAEMGYKTLVLSTDPAHSLADSFAVELGHQPKEVCQ
CEEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHH
NLWGAELDVLEELEQNWGSVKRYITEVLQARGLEGVQAEELAILPGSDEIFGLVRVFRHF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHH
KEGNYDVLIIDSAPTGTALRLLSIPEVAGWYMRRFYKPLEKVAVTLRPIVEPLFRPIAGF
CCCCEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPDKEMMDVPYDFYQKIEKLGEILMDNAVTSVRLVTNPEKMVLNESLRAHAYLSLYDIS
CCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEEEEEEECC
TDLIIANRIIPDEVTDPYFQYWKENQKIYRAEIHENFKPLPVKEVPLYSREICGLKTLDT
CCEEEECCCCCCCCCCHHHHHHHCCCCEEEHHHHCCCCCCCCCCCCCHHHHHCCCHHHHH
LKDLLYGDEDPSQVYYKEKTMRVEQVKNGYTLEIALPGIQKDRIEISKKGDELNIRIGNH
HHHHHCCCCCCHHEEHHHHHHHHHHHCCCEEEEEEECCCCCCCEEHCCCCCEEEEEECCC
RRNLVLPQALATLKTAGAEMEDELLKISFEEINVRKKGK
CCCEEHHHHHHHHHHCCCCHHHHHHHEEHHHHCCCCCCC
>Mature Secondary Structure
MRLILMTGKGGVGKTSMAAATGLKCAEMGYKTLVLSTDPAHSLADSFAVELGHQPKEVCQ
CEEEEEECCCCCCCHHHHHHHCCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHH
NLWGAELDVLEELEQNWGSVKRYITEVLQARGLEGVQAEELAILPGSDEIFGLVRVFRHF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHH
KEGNYDVLIIDSAPTGTALRLLSIPEVAGWYMRRFYKPLEKVAVTLRPIVEPLFRPIAGF
CCCCEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPDKEMMDVPYDFYQKIEKLGEILMDNAVTSVRLVTNPEKMVLNESLRAHAYLSLYDIS
CCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEEEEEEECC
TDLIIANRIIPDEVTDPYFQYWKENQKIYRAEIHENFKPLPVKEVPLYSREICGLKTLDT
CCEEEECCCCCCCCCCHHHHHHHCCCCEEEHHHHCCCCCCCCCCCCCHHHHHCCCHHHHH
LKDLLYGDEDPSQVYYKEKTMRVEQVKNGYTLEIALPGIQKDRIEISKKGDELNIRIGNH
HHHHHCCCCCCHHEEHHHHHHHHHHHCCCEEEEEEECCCCCCCEEHCCCCCEEEEEECCC
RRNLVLPQALATLKTAGAEMEDELLKISFEEINVRKKGK
CCCEEHHHHHHHHHHCCCCHHHHHHHEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]