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The map label for this gene is pol [H]

Identifier: 189499007

GI number: 189499007

Start: 7022

End: 9412

Strand: Reverse

Name: pol [H]

Synonym: Cphamn1_0007

Alternate gene names: 189499007

Gene position: 9412-7022 (Counterclockwise)

Preceding gene: 189499008

Following gene: 189499006

Centisome position: 0.34

GC content: 42.99

Gene sequence:

>2391_bases
ATGAGTAACAACCAACAGAACAACATCGTTTTGAACCCTCTTCTGTTCGGTAAGGATGAGGAGGAAAAAATCGTAGGCAT
TCACCAGTTACCGGACAATAAGGTCAGGCTGTACATCAGGGATGAAAACGGGATCAGCAGCCGTGACGAAGCGTTTTACC
CCTTCTTTTTTCTTTCAGAAGAGTCCTTACTTGACGGGTTTACTCCTGTAAACAGTGAGAAATTCTGGCTCATAAAACTT
CAAGGCGGGAATTTCTATCGATTCCTTGCGATTTTCAAAACACAGCAAAACTGTAGAAGTGCCCTTGAGTATATCGCATC
AAAATCAGCTGTCGATTCTGAGGAAGAGGATGATTCCGGCTTTTCAAGCAACCTGACCTACAGCAGGGGAGATGCTGTAA
CGCAATACCTGCTCCAATCAGGCAAGACGCTTTTTAAAGGCATGGTGCTTGAAGATCTTCACAGAATGCAGCTCGATATT
GAGACCTATTACAAACCCGAAAAAAACACGCGCAGCAAGGTTTCAATTGGAAGTGACCCGATAATCATCATATCTCTCAG
CGATAATAAGGGCTGGGAGCATAGTATTCATTCCAGAGATATATCTGAAAAAGAGTTGTTGGAAAAGCTGATTTCCATCA
TCCGGTTGAAAGATCCTGATGTTATCGAGGGACATAATATCTTCAGTTTTGACCTCCCTTACATACAGAGAAGATGTGAA
ATACTTGGTGTGGAGTTCAGGATAGGGCGTGACGGATCTATACCAAGAAGTTATCAATCCAGCATCCGATTTGCTGAACG
GTCGATTGACTACCCCTTTTTCGACATCGCAGGCAGACATGTTGTAGACACCCTGTTTCTTGTTCAGAATTATGATGTGG
CAAAACGCTCGATGCCTGGTTACGGCCTTAAAGCAGCAGCCAGATATTTCGGCTTTGCGTCGCCAGACAGAACCTATGTT
GAATACAGTGACATTGCCGATCTCTGGAACAACAACCCTGAACGACTTCTGAACTACGCTCTCGATGATGTGCGTGAAAC
ACAAAAGCTTGCAGCAATGCTTTCAGGCAGCAACTTCTACATGACCAGAATGATGCCCTATACCTATGCACAGACATCGA
GAATGGGGCCTGCGGCAAAGATAGAGGCCCTGTTTGTAAGGGACTATCTCAAAGAAAAGCATTCACTTCCAAAACCGGAA
ACAGGTCAGCAGCACTCCGGTGGGTTCACCGAAGTCTTTCTTAAAGGTATTCTCGGACCAATAGTCTATGCTGATGTAGA
ATCTCTCTATCCATCAATTATGCTCTTCTATGATATCTGCCCTAAAAGCGATGAACGGAGGATATTTCCTGAAATTCTGA
GTAGCCTGAAAGAGCTCCGTTTTGCAACAAAAAGCAAAGCAAAGGAGGAAAAAGAGAAGGGGAACAAGGATCTTTCGGAC
AATTACGATGCGATGCAGTCATCATTCAAGATATTGATTAACGCAATGTACGGCTATCTTGGATACAGTGCAGGCATATT
CAACGATTACGAAGAAGCCGACAGAGTAACAACGACCGGTCAGGAGATTGCGCGCAGGATGATCAAAGAATTTGAATCGA
GAGGTTGCAAGGTTATCGAAGTGGATACTGACGGCATACTTTTCGTTCCGCCACCTCATGTTCAGTCACAAGAAGATGAA
ATCAAACTCGTAAAGGAGGTTTCCGCGGTAATGCCCGACGGTATCACTATAGGATATGACGGACGATACAGAAAAATGAT
ATCCTATCTGAAAAAAAATTATGCTCTTCTCAACTATGATGGCACCATAAAACTTAAAGGATCCTCGCTCATAAGCAGGA
GCGGTGAAAAATTCGGACGCGATTTTATCCGCAAAGGGTTTGAAAAACTTCTTGAAGAAGATGTTCAGGGCCTGCACGAC
CTCTATGTTTCATTCAAGGAGATGATTATGAATCATAGCTGGTCCATAGAAGATTTTTCAAGGACTGAGTCACTGAAAAA
CACTCTGGAGCAATACATTACCGATACATCTTCAGGAAAAAGAAGCCGTTCGATAACCTATGAGCTTGCGCTGAAACATA
AACTGAGCGTCAATAAAGGGGACAGAATAACATACTATGTAGCCGGAAGCGGACTGCAAAGCAGCCACTATGAAAAAGGG
CGCCTTGCTGATGACTGGGACAGCTCCAAACCGGATGAAAACACGCAGTTTTACACAAAAAGACTTGATGAATTCTCACA
GAAATTTCTCCCTTTTTTCAAACCACAGGATTTCAGTTCAATTTTCTCCTCGGATACATTATTTTCATTTTCTCCTGAAG
GTATAGAGCTTATCAAAGAGATCAGAAACAAGGATACTGATTCATTTGATGATAACGATATACCATTTTAA

Upstream 100 bases:

>100_bases
GTCCTCATGGTGAAAATAGGCCGATAGAGCGACTTAACAGAGATGTTTCACGTGAAACGTTCAATTCTCACGTTCACGTC
TAACGAGATACAAAACTGAT

Downstream 100 bases:

>100_bases
ATTAATACAGTAACCGACAGATAAAACAATTTCACTCTTTCTGCTCATACAACTGACATGACAACAATTTTTTTGCTATC
AAGGAACTTAATGGTTTGTT

Product: DNA polymerase B region

Products: NA

Alternate protein names: Pfu polymerase [H]

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MSNNQQNNIVLNPLLFGKDEEEKIVGIHQLPDNKVRLYIRDENGISSRDEAFYPFFFLSEESLLDGFTPVNSEKFWLIKL
QGGNFYRFLAIFKTQQNCRSALEYIASKSAVDSEEEDDSGFSSNLTYSRGDAVTQYLLQSGKTLFKGMVLEDLHRMQLDI
ETYYKPEKNTRSKVSIGSDPIIIISLSDNKGWEHSIHSRDISEKELLEKLISIIRLKDPDVIEGHNIFSFDLPYIQRRCE
ILGVEFRIGRDGSIPRSYQSSIRFAERSIDYPFFDIAGRHVVDTLFLVQNYDVAKRSMPGYGLKAAARYFGFASPDRTYV
EYSDIADLWNNNPERLLNYALDDVRETQKLAAMLSGSNFYMTRMMPYTYAQTSRMGPAAKIEALFVRDYLKEKHSLPKPE
TGQQHSGGFTEVFLKGILGPIVYADVESLYPSIMLFYDICPKSDERRIFPEILSSLKELRFATKSKAKEEKEKGNKDLSD
NYDAMQSSFKILINAMYGYLGYSAGIFNDYEEADRVTTTGQEIARRMIKEFESRGCKVIEVDTDGILFVPPPHVQSQEDE
IKLVKEVSAVMPDGITIGYDGRYRKMISYLKKNYALLNYDGTIKLKGSSLISRSGEKFGRDFIRKGFEKLLEEDVQGLHD
LYVSFKEMIMNHSWSIEDFSRTESLKNTLEQYITDTSSGKRSRSITYELALKHKLSVNKGDRITYYVAGSGLQSSHYEKG
RLADDWDSSKPDENTQFYTKRLDEFSQKFLPFFKPQDFSSIFSSDTLFSFSPEGIELIKEIRNKDTDSFDDNDIPF

Sequences:

>Translated_796_residues
MSNNQQNNIVLNPLLFGKDEEEKIVGIHQLPDNKVRLYIRDENGISSRDEAFYPFFFLSEESLLDGFTPVNSEKFWLIKL
QGGNFYRFLAIFKTQQNCRSALEYIASKSAVDSEEEDDSGFSSNLTYSRGDAVTQYLLQSGKTLFKGMVLEDLHRMQLDI
ETYYKPEKNTRSKVSIGSDPIIIISLSDNKGWEHSIHSRDISEKELLEKLISIIRLKDPDVIEGHNIFSFDLPYIQRRCE
ILGVEFRIGRDGSIPRSYQSSIRFAERSIDYPFFDIAGRHVVDTLFLVQNYDVAKRSMPGYGLKAAARYFGFASPDRTYV
EYSDIADLWNNNPERLLNYALDDVRETQKLAAMLSGSNFYMTRMMPYTYAQTSRMGPAAKIEALFVRDYLKEKHSLPKPE
TGQQHSGGFTEVFLKGILGPIVYADVESLYPSIMLFYDICPKSDERRIFPEILSSLKELRFATKSKAKEEKEKGNKDLSD
NYDAMQSSFKILINAMYGYLGYSAGIFNDYEEADRVTTTGQEIARRMIKEFESRGCKVIEVDTDGILFVPPPHVQSQEDE
IKLVKEVSAVMPDGITIGYDGRYRKMISYLKKNYALLNYDGTIKLKGSSLISRSGEKFGRDFIRKGFEKLLEEDVQGLHD
LYVSFKEMIMNHSWSIEDFSRTESLKNTLEQYITDTSSGKRSRSITYELALKHKLSVNKGDRITYYVAGSGLQSSHYEKG
RLADDWDSSKPDENTQFYTKRLDEFSQKFLPFFKPQDFSSIFSSDTLFSFSPEGIELIKEIRNKDTDSFDDNDIPF
>Mature_795_residues
SNNQQNNIVLNPLLFGKDEEEKIVGIHQLPDNKVRLYIRDENGISSRDEAFYPFFFLSEESLLDGFTPVNSEKFWLIKLQ
GGNFYRFLAIFKTQQNCRSALEYIASKSAVDSEEEDDSGFSSNLTYSRGDAVTQYLLQSGKTLFKGMVLEDLHRMQLDIE
TYYKPEKNTRSKVSIGSDPIIIISLSDNKGWEHSIHSRDISEKELLEKLISIIRLKDPDVIEGHNIFSFDLPYIQRRCEI
LGVEFRIGRDGSIPRSYQSSIRFAERSIDYPFFDIAGRHVVDTLFLVQNYDVAKRSMPGYGLKAAARYFGFASPDRTYVE
YSDIADLWNNNPERLLNYALDDVRETQKLAAMLSGSNFYMTRMMPYTYAQTSRMGPAAKIEALFVRDYLKEKHSLPKPET
GQQHSGGFTEVFLKGILGPIVYADVESLYPSIMLFYDICPKSDERRIFPEILSSLKELRFATKSKAKEEKEKGNKDLSDN
YDAMQSSFKILINAMYGYLGYSAGIFNDYEEADRVTTTGQEIARRMIKEFESRGCKVIEVDTDGILFVPPPHVQSQEDEI
KLVKEVSAVMPDGITIGYDGRYRKMISYLKKNYALLNYDGTIKLKGSSLISRSGEKFGRDFIRKGFEKLLEEDVQGLHDL
YVSFKEMIMNHSWSIEDFSRTESLKNTLEQYITDTSSGKRSRSITYELALKHKLSVNKGDRITYYVAGSGLQSSHYEKGR
LADDWDSSKPDENTQFYTKRLDEFSQKFLPFFKPQDFSSIFSSDTLFSFSPEGIELIKEIRNKDTDSFDDNDIPF

Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity [H]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Escherichia coli, GI1786246, Length=411, Percent_Identity=25.5474452554745, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17559488, Length=588, Percent_Identity=25.8503401360544, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32565317, Length=575, Percent_Identity=22.9565217391304, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320101, Length=574, Percent_Identity=23.8675958188153, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR004578
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 91480; Mature: 91349

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNQQNNIVLNPLLFGKDEEEKIVGIHQLPDNKVRLYIRDENGISSRDEAFYPFFFLSE
CCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEECC
ESLLDGFTPVNSEKFWLIKLQGGNFYRFLAIFKTQQNCRSALEYIASKSAVDSEEEDDSG
HHHHCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FSSNLTYSRGDAVTQYLLQSGKTLFKGMVLEDLHRMQLDIETYYKPEKNTRSKVSIGSDP
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEECCCC
IIIISLSDNKGWEHSIHSRDISEKELLEKLISIIRLKDPDVIEGHNIFSFDLPYIQRRCE
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCEEEECCHHHHHHHH
ILGVEFRIGRDGSIPRSYQSSIRFAERSIDYPFFDIAGRHVVDTLFLVQNYDVAKRSMPG
HEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHCCCHHHHCCCC
YGLKAAARYFGFASPDRTYVEYSDIADLWNNNPERLLNYALDDVRETQKLAAMLSGSNFY
CCHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MTRMMPYTYAQTSRMGPAAKIEALFVRDYLKEKHSLPKPETGQQHSGGFTEVFLKGILGP
EEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
IVYADVESLYPSIMLFYDICPKSDERRIFPEILSSLKELRFATKSKAKEEKEKGNKDLSD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NYDAMQSSFKILINAMYGYLGYSAGIFNDYEEADRVTTTGQEIARRMIKEFESRGCKVIE
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEE
VDTDGILFVPPPHVQSQEDEIKLVKEVSAVMPDGITIGYDGRYRKMISYLKKNYALLNYD
ECCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCEEEECC
GTIKLKGSSLISRSGEKFGRDFIRKGFEKLLEEDVQGLHDLYVSFKEMIMNHSWSIEDFS
CEEEECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RTESLKNTLEQYITDTSSGKRSRSITYELALKHKLSVNKGDRITYYVAGSGLQSSHYEKG
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCC
RLADDWDSSKPDENTQFYTKRLDEFSQKFLPFFKPQDFSSIFSSDTLFSFSPEGIELIKE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEECCHHHHHHHH
IRNKDTDSFDDNDIPF
HHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNNQQNNIVLNPLLFGKDEEEKIVGIHQLPDNKVRLYIRDENGISSRDEAFYPFFFLSE
CCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEECC
ESLLDGFTPVNSEKFWLIKLQGGNFYRFLAIFKTQQNCRSALEYIASKSAVDSEEEDDSG
HHHHCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FSSNLTYSRGDAVTQYLLQSGKTLFKGMVLEDLHRMQLDIETYYKPEKNTRSKVSIGSDP
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEECCCC
IIIISLSDNKGWEHSIHSRDISEKELLEKLISIIRLKDPDVIEGHNIFSFDLPYIQRRCE
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCEEEECCHHHHHHHH
ILGVEFRIGRDGSIPRSYQSSIRFAERSIDYPFFDIAGRHVVDTLFLVQNYDVAKRSMPG
HEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHCCCHHHHCCCC
YGLKAAARYFGFASPDRTYVEYSDIADLWNNNPERLLNYALDDVRETQKLAAMLSGSNFY
CCHHHHHHHHCCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MTRMMPYTYAQTSRMGPAAKIEALFVRDYLKEKHSLPKPETGQQHSGGFTEVFLKGILGP
EEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
IVYADVESLYPSIMLFYDICPKSDERRIFPEILSSLKELRFATKSKAKEEKEKGNKDLSD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NYDAMQSSFKILINAMYGYLGYSAGIFNDYEEADRVTTTGQEIARRMIKEFESRGCKVIE
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEE
VDTDGILFVPPPHVQSQEDEIKLVKEVSAVMPDGITIGYDGRYRKMISYLKKNYALLNYD
ECCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCEEEECC
GTIKLKGSSLISRSGEKFGRDFIRKGFEKLLEEDVQGLHDLYVSFKEMIMNHSWSIEDFS
CEEEECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RTESLKNTLEQYITDTSSGKRSRSITYELALKHKLSVNKGDRITYYVAGSGLQSSHYEKG
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCC
RLADDWDSSKPDENTQFYTKRLDEFSQKFLPFFKPQDFSSIFSSDTLFSFSPEGIELIKE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEECCHHHHHHHH
IRNKDTDSFDDNDIPF
HHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8441634; 1762925; 1579479 [H]