Click here to switch to the map view.

The map label for this gene is trpB [H]

Identifier: 189424276

GI number: 189424276

Start: 1257177

End: 1258367

Strand: Reverse

Name: trpB [H]

Synonym: Glov_1211

Alternate gene names: 189424276

Gene position: 1258367-1257177 (Counterclockwise)

Preceding gene: 189424277

Following gene: 189424275

Centisome position: 32.12

GC content: 60.87

Gene sequence:

>1191_bases
ATGAAACAACCCGATAAACACGGCCACTTCGGTATCCACGGCGGACGCTATGTGCCTGAAACCCTGATGCCTGCCCTGAA
GGAGCTGGAAGAGGCCTATGCTCACTATAAGAATGACCGCGAATTTAAGCAGGAGTTTCAGTACTACCTGCGGGAATATG
TGGGCCGTCCTTCGCCGCTCTACTTTGCCGAGAAACTGACCAAACAGCTTGGCGGCGCGAAGATCTACCTGAAGCGTGAA
GACCTGAACCATACCGGAGCCCACAAGGTCAACAACACCATCGGCCAGGGACTGCTTGCCAAACGGATGAAAAAAGAGCG
GGTGATCGCCGAGACCGGTGCCGGTCAGCACGGCGTGGCCACCGCCACCATTGCCGCCCTGTTCGGCATGCAGTGCGAGG
TGTTCATGGGTGCTGAGGATATCCGGCGTCAGGCACTGAACGTCTTCCGGATGAAGCTGCTGGGGGCCACCGTCAATCCG
GTGACTGCCGGCACTGCCACCCTCAAGGATGCCATGAACGAGGCGCTGCGGGACTGGGTTACCAACATCCGTACCACGTT
TTATGTGATCGGCACCGTAGCCGGTCCCCATCCCTACCCGGTGATGGTGCGTGACTTTCAGTCGGTGATCGGCATTGAGG
CCAAGAAGCAGCACAAGAAGGTCGAAGGCCGCCTGCCGGATGCCCTGGTGGCCTGCGTTGGCGGCGGCAGTAACGCCATG
GGGCTGTTCTACCCCTTCCTGAAGGATAGCGGCGTCCGCCTGATCGGTGTTGAGGCAGCCGGGCACGGCATTGCCTCCGG
TGCCCATGCGGCGCCACTCTGCGCCGGTCGCCCCGGTATCCTGCATGGTCAGCGCAGCTACCTGCTGCAGGACACCCACG
GACAGGTCGCCAATGCCCACTCCATTTCCGCCGGCCTGGACTACCCCGGCGTCGGCCCGGAACATGCCTGGCTCAAGGAC
ACCGGCCGGGCCGAGTATGTCTCGATCACCGACGATGAGGCACTGGAGGCGTTCCAGCGTCTGACCCGTGAAGAAGGGAT
CATGCCGGCCCTGGAATCCTCCCACGCCATCGCCCACACCCTCAAACTGGCTCCCGGCATGTCCAAGGACCAGACCATTG
TGGTCTGTCTCTCAGGTCGTGGCGACAAGGATATCCATACCGTTGCCGATGCCTTGGGCGTAAAATTTTAA

Upstream 100 bases:

>100_bases
CCTATGCCGTTGATGTCTCCAGCGGCGTGGAATCAGCACCCGGCAGAAAAGATGCAGACAAGGTACGAGAGTTTATACGC
AATGCAAAGGAAGCCTTATA

Downstream 100 bases:

>100_bases
TCTGGTTTTATACCTGTTTCAGCCAAACTAAAGCCGCGTTTCAGCGGCTTTTTTTGTTGACGATCAGGGCCCATTCAGGT
ATCTAGCAAAAACTTGTTTT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKQPDKHGHFGIHGGRYVPETLMPALKELEEAYAHYKNDREFKQEFQYYLREYVGRPSPLYFAEKLTKQLGGAKIYLKRE
DLNHTGAHKVNNTIGQGLLAKRMKKERVIAETGAGQHGVATATIAALFGMQCEVFMGAEDIRRQALNVFRMKLLGATVNP
VTAGTATLKDAMNEALRDWVTNIRTTFYVIGTVAGPHPYPVMVRDFQSVIGIEAKKQHKKVEGRLPDALVACVGGGSNAM
GLFYPFLKDSGVRLIGVEAAGHGIASGAHAAPLCAGRPGILHGQRSYLLQDTHGQVANAHSISAGLDYPGVGPEHAWLKD
TGRAEYVSITDDEALEAFQRLTREEGIMPALESSHAIAHTLKLAPGMSKDQTIVVCLSGRGDKDIHTVADALGVKF

Sequences:

>Translated_396_residues
MKQPDKHGHFGIHGGRYVPETLMPALKELEEAYAHYKNDREFKQEFQYYLREYVGRPSPLYFAEKLTKQLGGAKIYLKRE
DLNHTGAHKVNNTIGQGLLAKRMKKERVIAETGAGQHGVATATIAALFGMQCEVFMGAEDIRRQALNVFRMKLLGATVNP
VTAGTATLKDAMNEALRDWVTNIRTTFYVIGTVAGPHPYPVMVRDFQSVIGIEAKKQHKKVEGRLPDALVACVGGGSNAM
GLFYPFLKDSGVRLIGVEAAGHGIASGAHAAPLCAGRPGILHGQRSYLLQDTHGQVANAHSISAGLDYPGVGPEHAWLKD
TGRAEYVSITDDEALEAFQRLTREEGIMPALESSHAIAHTLKLAPGMSKDQTIVVCLSGRGDKDIHTVADALGVKF
>Mature_396_residues
MKQPDKHGHFGIHGGRYVPETLMPALKELEEAYAHYKNDREFKQEFQYYLREYVGRPSPLYFAEKLTKQLGGAKIYLKRE
DLNHTGAHKVNNTIGQGLLAKRMKKERVIAETGAGQHGVATATIAALFGMQCEVFMGAEDIRRQALNVFRMKLLGATVNP
VTAGTATLKDAMNEALRDWVTNIRTTFYVIGTVAGPHPYPVMVRDFQSVIGIEAKKQHKKVEGRLPDALVACVGGGSNAM
GLFYPFLKDSGVRLIGVEAAGHGIASGAHAAPLCAGRPGILHGQRSYLLQDTHGQVANAHSISAGLDYPGVGPEHAWLKD
TGRAEYVSITDDEALEAFQRLTREEGIMPALESSHAIAHTLKLAPGMSKDQTIVVCLSGRGDKDIHTVADALGVKF

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=385, Percent_Identity=57.9220779220779, Blast_Score=454, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6321412, Length=392, Percent_Identity=58.1632653061224, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43077; Mature: 43077

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQPDKHGHFGIHGGRYVPETLMPALKELEEAYAHYKNDREFKQEFQYYLREYVGRPSPL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCH
YFAEKLTKQLGGAKIYLKREDLNHTGAHKVNNTIGQGLLAKRMKKERVIAETGAGQHGVA
HHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
TATIAALFGMQCEVFMGAEDIRRQALNVFRMKLLGATVNPVTAGTATLKDAMNEALRDWV
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TNIRTTFYVIGTVAGPHPYPVMVRDFQSVIGIEAKKQHKKVEGRLPDALVACVGGGSNAM
HHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHEEEECCCCCCH
GLFYPFLKDSGVRLIGVEAAGHGIASGAHAAPLCAGRPGILHGQRSYLLQDTHGQVANAH
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCC
SISAGLDYPGVGPEHAWLKDTGRAEYVSITDDEALEAFQRLTREEGIMPALESSHAIAHT
CCCCCCCCCCCCCCCCHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHCCHHHHHH
LKLAPGMSKDQTIVVCLSGRGDKDIHTVADALGVKF
HHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKQPDKHGHFGIHGGRYVPETLMPALKELEEAYAHYKNDREFKQEFQYYLREYVGRPSPL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCH
YFAEKLTKQLGGAKIYLKREDLNHTGAHKVNNTIGQGLLAKRMKKERVIAETGAGQHGVA
HHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
TATIAALFGMQCEVFMGAEDIRRQALNVFRMKLLGATVNPVTAGTATLKDAMNEALRDWV
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TNIRTTFYVIGTVAGPHPYPVMVRDFQSVIGIEAKKQHKKVEGRLPDALVACVGGGSNAM
HHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHEEEECCCCCCH
GLFYPFLKDSGVRLIGVEAAGHGIASGAHAAPLCAGRPGILHGQRSYLLQDTHGQVANAH
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCCCCCC
SISAGLDYPGVGPEHAWLKDTGRAEYVSITDDEALEAFQRLTREEGIMPALESSHAIAHT
CCCCCCCCCCCCCCCCHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHCCHHHHHH
LKLAPGMSKDQTIVVCLSGRGDKDIHTVADALGVKF
HHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA