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The map label for this gene is cysM [H]

Identifier: 189424090

GI number: 189424090

Start: 1064802

End: 1065719

Strand: Reverse

Name: cysM [H]

Synonym: Glov_1024

Alternate gene names: 189424090

Gene position: 1065719-1064802 (Counterclockwise)

Preceding gene: 189424099

Following gene: 189424089

Centisome position: 27.2

GC content: 60.13

Gene sequence:

>918_bases
ATGCTCGGACAACCGCTTCTTGATGCCATCGGCAACACCCCCCTGGTTCAGATCACTGCAATCAATCCCAACCCCCGTGT
TCGTATTCTTGCAAAACTTGAAGGAAACAACCCCGGAGGCTCGATCAAGGACCGCCCTGCCCGCCAGATGATCCTGGCAG
CTGAGGCATCCGGCGAACTGACTACCGACAAAACCATTCTCGAACCCACCTCCGGCAACACCGGGATCGCCCTGGCCATG
ATTGCGGCGGCCCGCGGTTACCGGATCAAGCTGGCCATGCCCGCCTGTGTCAGCATGGAACGGCGTAGCGTGCTTGAGGC
CTACGGCGCCGAGATCGTACTTTCACCCGGCTGCGAGAAGACCGACGGTGCCATCCGTCTGGCACACAAGATCTACGGCG
AAGAGCCGGGGCACTACTACATGCCCAATCAGTACGACAACCCTAACAACCCGCTGGCCCATGAACTGACCACCGGGCCG
GAAATCCTGTCTCAGACCGGTGGCGATCTGACCCATTTCGTGGCCGGCATGGGCACCGGCGGCACCCTGATGGGAACTGC
GGCCTGCCTCCGCAAACAGGCCCCAGGCGTACAGGTGATCGGAGTGGAGCCTAACCTGGGACATGCCATTCAGGGCCTTA
AGAACATGCAGGAGGCAATTGTCCCGGCCATCTATCACGAGGAGCAGCTTCACCGCAAGATCGTGATCGATGACGAGACC
GCCTTTGAAACCTCCCGGCAACTGGCCTCCCACGAAGGAATCTTCTGCGGCATGTCCGGTGGAGCAGCCATGGCCGGCGC
CTTCAAGCTGGCGCAAGAACTTGAAAGCGGCACGATTGTGGTGATTATTCCTGACCGTGGGGATCGCTACCTGAGCACGA
ACCTGTTCAAGTCCATGTGTGCCAACTGCCCCCCCTGA

Upstream 100 bases:

>100_bases
ATATCTGCTTGACCCCCTGCCGACGACAGGCTATAAAAACAACTTCAATCAACAAATCACGCAATTCAAATTTACTACTT
ATTTCAGGCAGGTACCTTTG

Downstream 100 bases:

>100_bases
CAGTGTTTTTAAAATCGTCATGAGGAAGCCCGGATACACGGCGCACAGCAACCGAGACATAACAAACAGTTAGACGAGCA
AGCGAACACCGCGCAACGCC

Product: cysteine synthase

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLGQPLLDAIGNTPLVQITAINPNPRVRILAKLEGNNPGGSIKDRPARQMILAAEASGELTTDKTILEPTSGNTGIALAM
IAAARGYRIKLAMPACVSMERRSVLEAYGAEIVLSPGCEKTDGAIRLAHKIYGEEPGHYYMPNQYDNPNNPLAHELTTGP
EILSQTGGDLTHFVAGMGTGGTLMGTAACLRKQAPGVQVIGVEPNLGHAIQGLKNMQEAIVPAIYHEEQLHRKIVIDDET
AFETSRQLASHEGIFCGMSGGAAMAGAFKLAQELESGTIVVIIPDRGDRYLSTNLFKSMCANCPP

Sequences:

>Translated_305_residues
MLGQPLLDAIGNTPLVQITAINPNPRVRILAKLEGNNPGGSIKDRPARQMILAAEASGELTTDKTILEPTSGNTGIALAM
IAAARGYRIKLAMPACVSMERRSVLEAYGAEIVLSPGCEKTDGAIRLAHKIYGEEPGHYYMPNQYDNPNNPLAHELTTGP
EILSQTGGDLTHFVAGMGTGGTLMGTAACLRKQAPGVQVIGVEPNLGHAIQGLKNMQEAIVPAIYHEEQLHRKIVIDDET
AFETSRQLASHEGIFCGMSGGAAMAGAFKLAQELESGTIVVIIPDRGDRYLSTNLFKSMCANCPP
>Mature_305_residues
MLGQPLLDAIGNTPLVQITAINPNPRVRILAKLEGNNPGGSIKDRPARQMILAAEASGELTTDKTILEPTSGNTGIALAM
IAAARGYRIKLAMPACVSMERRSVLEAYGAEIVLSPGCEKTDGAIRLAHKIYGEEPGHYYMPNQYDNPNNPLAHELTTGP
EILSQTGGDLTHFVAGMGTGGTLMGTAACLRKQAPGVQVIGVEPNLGHAIQGLKNMQEAIVPAIYHEEQLHRKIVIDDET
AFETSRQLASHEGIFCGMSGGAAMAGAFKLAQELESGTIVVIIPDRGDRYLSTNLFKSMCANCPP

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=308, Percent_Identity=39.9350649350649, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI295821200, Length=308, Percent_Identity=39.9350649350649, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI4557415, Length=308, Percent_Identity=39.9350649350649, Blast_Score=196, Evalue=2e-50,
Organism=Escherichia coli, GI2367138, Length=291, Percent_Identity=46.0481099656357, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI1788754, Length=308, Percent_Identity=42.8571428571429, Blast_Score=196, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17535051, Length=305, Percent_Identity=39.344262295082, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17562970, Length=302, Percent_Identity=38.0794701986755, Blast_Score=188, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI115535073, Length=303, Percent_Identity=40.5940594059406, Blast_Score=186, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI32566674, Length=294, Percent_Identity=38.7755102040816, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17561720, Length=306, Percent_Identity=36.2745098039216, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17534315, Length=318, Percent_Identity=35.5345911949685, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25147552, Length=312, Percent_Identity=32.0512820512821, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI32566672, Length=216, Percent_Identity=33.7962962962963, Blast_Score=120, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6321594, Length=319, Percent_Identity=37.3040752351097, Blast_Score=178, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6321449, Length=321, Percent_Identity=32.398753894081, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24643623, Length=306, Percent_Identity=35.2941176470588, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI20129101, Length=306, Percent_Identity=35.2941176470588, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 32412; Mature: 32412

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00901 CYS_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGQPLLDAIGNTPLVQITAINPNPRVRILAKLEGNNPGGSIKDRPARQMILAAEASGEL
CCCCHHHHHHCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
TTDKTILEPTSGNTGIALAMIAAARGYRIKLAMPACVSMERRSVLEAYGAEIVLSPGCEK
CCCCEEECCCCCCCCHHHHEEHHCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCC
TDGAIRLAHKIYGEEPGHYYMPNQYDNPNNPLAHELTTGPEILSQTGGDLTHFVAGMGTG
CCCCEEEEHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCC
GTLMGTAACLRKQAPGVQVIGVEPNLGHAIQGLKNMQEAIVPAIYHEEQLHRKIVIDDET
CHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCH
AFETSRQLASHEGIFCGMSGGAAMAGAFKLAQELESGTIVVIIPDRGDRYLSTNLFKSMC
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
ANCPP
CCCCC
>Mature Secondary Structure
MLGQPLLDAIGNTPLVQITAINPNPRVRILAKLEGNNPGGSIKDRPARQMILAAEASGEL
CCCCHHHHHHCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
TTDKTILEPTSGNTGIALAMIAAARGYRIKLAMPACVSMERRSVLEAYGAEIVLSPGCEK
CCCCEEECCCCCCCCHHHHEEHHCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCC
TDGAIRLAHKIYGEEPGHYYMPNQYDNPNNPLAHELTTGPEILSQTGGDLTHFVAGMGTG
CCCCEEEEHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCC
GTLMGTAACLRKQAPGVQVIGVEPNLGHAIQGLKNMQEAIVPAIYHEEQLHRKIVIDDET
CHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCH
AFETSRQLASHEGIFCGMSGGAAMAGAFKLAQELESGTIVVIIPDRGDRYLSTNLFKSMC
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
ANCPP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]