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The map label for this gene is prmA

Identifier: 189424062

GI number: 189424062

Start: 1034297

End: 1035214

Strand: Reverse

Name: prmA

Synonym: Glov_0996

Alternate gene names: 189424062

Gene position: 1035214-1034297 (Counterclockwise)

Preceding gene: 189424067

Following gene: 189424061

Centisome position: 26.42

GC content: 60.78

Gene sequence:

>918_bases
ATGGCTGCAACATGGTACCAAGTCACCTGTGACGTTCCAGCCCAGCTTGCCGAAACCGTGGCTGACTACCTGGCTGACCT
CTCCGGCTGTGGAGTCTGCACGGAAAACCGGGATGTTGACAGCTTTTCACCGGACGATATTCCCGAGCTGGCCATTTCCC
AGATCACCTGCTACTTCAGCCTCCCTTGCCGGATCGAACAACAGCTGGCACAGATCACCGGTTTTCTTGCCGCCCTGCCC
GGCTACATACCGGCAGCACCGCCCCGGGTCTCCCTGCTGGGTGAAGAAGACTGGGCCAGTTCCTGGAAGGCACACTTCAA
ACCGCTCGCTATCGGGCAGCGCCTGCTGATCACCCCTTCATGGGAAACAGGCCGTCAGGACGAAGGACGGGCCGTCATCG
TACTTGACCCCGGCATGGCCTTCGGCACCGGCGGCCATGAGACCACCCGGCTCTGTCTGGAGTGCCTTGAAGGCCTGCTG
GTACCGCCACCTGAGCAGTTGGAACAGATCAAGATCCTGGACCTGGGAACCGGCTCCGGCATCCTGGCCATTGCTGCAGC
AAAACTGGGGGCTTTGCAAATCGATGCCGTTGATATTGATCCCCAGGCGGTCATCGTTGCCGAGGAAAACTGCGCCCTGA
ACAAGGTGGCTGACCGGATCAGCTGCAGCACCACACCACTTGAACAACTGGGGGACGGCTACCGGATCATCCTGGCCAAT
ATCCTGGCAGAAGAGCTGGTCAGAATGGCCCCCGGCATTGTCAGCCGTATGGCACCCGGCGGCAGCCTGATCCTTTCCGG
CATCCTGGCGGAACGGGAAGCGCTGGTCCGCAACGGCTTTGATCCGTTTCCGCTCAGCTTCGAGGCTTCTCTGGCAGCAG
GAGAATGGCGCTGCCTGCACTACCGGAGGCTGCCATGA

Upstream 100 bases:

>100_bases
TTTGTCAAGGTTTTTTGTTGTAAGAGCACCCCTGTTCTGCTACGTTCTGCCCACTTCTGCGGTATACTCCGCCAATCACC
TGCCCCTTGAGGTTCTATTC

Downstream 100 bases:

>100_bases
GCGGACGACGCCGCTTTATTGTCAGCTCCCGCAGCATCCGCGATGGCTACGCCTCCTATGACGGCCCCCAGCATCACCAC
ATGGCACGGGTGCTGCGGCT

Product: 50S ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAATWYQVTCDVPAQLAETVADYLADLSGCGVCTENRDVDSFSPDDIPELAISQITCYFSLPCRIEQQLAQITGFLAALP
GYIPAAPPRVSLLGEEDWASSWKAHFKPLAIGQRLLITPSWETGRQDEGRAVIVLDPGMAFGTGGHETTRLCLECLEGLL
VPPPEQLEQIKILDLGTGSGILAIAAAKLGALQIDAVDIDPQAVIVAEENCALNKVADRISCSTTPLEQLGDGYRIILAN
ILAEELVRMAPGIVSRMAPGGSLILSGILAEREALVRNGFDPFPLSFEASLAAGEWRCLHYRRLP

Sequences:

>Translated_305_residues
MAATWYQVTCDVPAQLAETVADYLADLSGCGVCTENRDVDSFSPDDIPELAISQITCYFSLPCRIEQQLAQITGFLAALP
GYIPAAPPRVSLLGEEDWASSWKAHFKPLAIGQRLLITPSWETGRQDEGRAVIVLDPGMAFGTGGHETTRLCLECLEGLL
VPPPEQLEQIKILDLGTGSGILAIAAAKLGALQIDAVDIDPQAVIVAEENCALNKVADRISCSTTPLEQLGDGYRIILAN
ILAEELVRMAPGIVSRMAPGGSLILSGILAEREALVRNGFDPFPLSFEASLAAGEWRCLHYRRLP
>Mature_304_residues
AATWYQVTCDVPAQLAETVADYLADLSGCGVCTENRDVDSFSPDDIPELAISQITCYFSLPCRIEQQLAQITGFLAALPG
YIPAAPPRVSLLGEEDWASSWKAHFKPLAIGQRLLITPSWETGRQDEGRAVIVLDPGMAFGTGGHETTRLCLECLEGLLV
PPPEQLEQIKILDLGTGSGILAIAAAKLGALQIDAVDIDPQAVIVAEENCALNKVADRISCSTTPLEQLGDGYRIILANI
LAEELVRMAPGIVSRMAPGGSLILSGILAEREALVRNGFDPFPLSFEASLAAGEWRCLHYRRLP

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=254, Percent_Identity=34.251968503937, Blast_Score=111, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_GEOLS (B3E5Z5)

Other databases:

- EMBL:   CP001089
- RefSeq:   YP_001951239.1
- ProteinModelPortal:   B3E5Z5
- SMR:   B3E5Z5
- GeneID:   6368596
- GenomeReviews:   CP001089_GR
- KEGG:   glo:Glov_0996
- HOGENOM:   HBG584653
- OMA:   AVDIEPW
- ProtClustDB:   CLSK827836
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32769; Mature: 32638

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATWYQVTCDVPAQLAETVADYLADLSGCGVCTENRDVDSFSPDDIPELAISQITCYFS
CCCEEEEEEECCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHEEEEEE
LPCRIEQQLAQITGFLAALPGYIPAAPPRVSLLGEEDWASSWKAHFKPLAIGQRLLITPS
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHCCHHHCCCEEEEECC
WETGRQDEGRAVIVLDPGMAFGTGGHETTRLCLECLEGLLVPPPEQLEQIKILDLGTGSG
CCCCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHCCCCCCHHHHCEEEEEEECCCCC
ILAIAAAKLGALQIDAVDIDPQAVIVAEENCALNKVADRISCSTTPLEQLGDGYRIILAN
HHHHHHHHHCEEEEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHH
ILAEELVRMAPGIVSRMAPGGSLILSGILAEREALVRNGFDPFPLSFEASLAAGEWRCLH
HHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEEEEE
YRRLP
EECCC
>Mature Secondary Structure 
AATWYQVTCDVPAQLAETVADYLADLSGCGVCTENRDVDSFSPDDIPELAISQITCYFS
CCEEEEEEECCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHEEEEEE
LPCRIEQQLAQITGFLAALPGYIPAAPPRVSLLGEEDWASSWKAHFKPLAIGQRLLITPS
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHCCHHHCCCEEEEECC
WETGRQDEGRAVIVLDPGMAFGTGGHETTRLCLECLEGLLVPPPEQLEQIKILDLGTGSG
CCCCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHCCCCCCHHHHCEEEEEEECCCCC
ILAIAAAKLGALQIDAVDIDPQAVIVAEENCALNKVADRISCSTTPLEQLGDGYRIILAN
HHHHHHHHHCEEEEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHH
ILAEELVRMAPGIVSRMAPGGSLILSGILAEREALVRNGFDPFPLSFEASLAAGEWRCLH
HHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEEEEE
YRRLP
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA