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The map label for this gene is hsdM [C]

Identifier: 189423917

GI number: 189423917

Start: 875448

End: 876938

Strand: Reverse

Name: hsdM [C]

Synonym: Glov_0850

Alternate gene names: 189423917

Gene position: 876938-875448 (Counterclockwise)

Preceding gene: 189423918

Following gene: 189423916

Centisome position: 22.38

GC content: 56.61

Gene sequence:

>1491_bases
ATGACGCTTCTCCCTCTTTCCCAACTCGAAAATCACCTCTGGGAATCAGCCAACATCCTCCGTGGGCCGGTCGATGCTGC
TGATTTCAAGACCTACATCTTTCCGCTCCTGTTTTTCAAGCGGATCTGTGACGTCTGGGATGAGGAGTATCAGGAAATCG
CAGAAGAGATGGGTGATCCGGAACTGGCGATGTTTCCCGAATCTCACCGATTCCAGGTGCCGGAAGGCTGTCACTGGCGG
GATATCCGTGAGACACCGGTCAATGTGGGCAATGCCCTGCAGCGGGCGCTCCGTGAAATCGAAAAGGCCAATCCGGATAC
GCTGTATGCGGTCTTTGGTGATGCCCAGTGGACCAACAAGGATCGCCTGACCGATGCTCTGCTGAAAGATCTGATCGAGC
ATTTCTCCCGGCTCCCCCTTGGCAACCGAAATGTCGCCTCGGATGTATTGGGCGATGCTTACGAATACCTGATCAAGAAA
TTTGCCGACGCCACCAACAAGAAAGCCGGCGAGTTCTACACCCCGCGTAGCGTTGTCCGGCTCATGGTGGATATGCTCGA
TCCAAAGGAAGGCGACTCCATTTATGACCCTGCCTGCGGTACCGGCGGCATGCTGCTGGCAGCCCTCCAGCACGTTCATG
AGCTGCATGGCGACACCAAGCTCCTCTGGGGCAAGCTGTTCGGCCAAGAAAAGAACCTGACTACTTCGGCCATCGCCCGG
ATGAACTTGTTCCTGCACGGTATTGAAGATTTCCAGATTGTCCGGGGCGACACCCTGCGCAATCCGGCTTTCTTTGAAGG
TGATCGTCTGGCGACGTTTGACTGCGTCATTGCCAATCCCCCCTTTTCACTGGAAAAGTGGGGGGAAGAAGTCTGGCTCA
ACGACCCATTCGGCCGCAACTTTGCCGGCCTTCCCCCCTCAAGCAGCGGTGATTTTGCCTGGGTACAGCACATGGTCAAG
TCCATGGCAGAAGTTACCGGACGGATGGCGGTGGTGTTGCCACAGGGAGCACTGTTCCGCAAAGGCGTGGAAGGTGAGAT
TCGCCGCAAGTTGCTGGAGATGGATCTGATAGAAGGTGTTATCGGCCTGGCGCCTAACCTGTTCTACGGTACCGGCCTTG
CTGCCTGCATCCTCCTGCTGCGCAAGCGCAAGCCGGCTGAACGCAAAAGGAAGGTGATGATCGCCGACGCCTCCAGCTTG
TTCCGGCGTGGCCGGGCACAGAATTACCTTGAGCCGGAACATGGTGCCGAGATTCTTGGCTGGTATCAGGCGTTCATCGA
TGTGCAGGATCGGGTGCGGATCGTCAGCACCGATGAGATAAAGGCCGAGGACTGGACCCTGAATATCTCACGTTATGTCT
TGCCGCCGCTCAATGACGACATTCCGCCGTTGCCCCAGGCCATAGCAGAGTTCAAGTCGGCTCTCGAACGCTGTCGCGAG
GCAGAGACCCGTCTGGAACAGTTAATGACGGATGGAGGCTGGTTGCAATGA

Upstream 100 bases:

>100_bases
TTCCCGATCCATGCCGCCGGCTGGTTTTTCCCGGAGCTGTACCCGGTGCTGTCACGTTAGGACCATGAACGTACCTTGCC
AAACTTGGAGTATCTGATTA

Downstream 100 bases:

>100_bases
GCTCGCGCATCTCTCAACAGGAATTGGAATCCTACCTCTGGGGTGCGGCAACGCTCCTGCGCGGACTGATCGACGCCGGC
GACTACAAGCAGTTCATCTT

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MTLLPLSQLENHLWESANILRGPVDAADFKTYIFPLLFFKRICDVWDEEYQEIAEEMGDPELAMFPESHRFQVPEGCHWR
DIRETPVNVGNALQRALREIEKANPDTLYAVFGDAQWTNKDRLTDALLKDLIEHFSRLPLGNRNVASDVLGDAYEYLIKK
FADATNKKAGEFYTPRSVVRLMVDMLDPKEGDSIYDPACGTGGMLLAALQHVHELHGDTKLLWGKLFGQEKNLTTSAIAR
MNLFLHGIEDFQIVRGDTLRNPAFFEGDRLATFDCVIANPPFSLEKWGEEVWLNDPFGRNFAGLPPSSSGDFAWVQHMVK
SMAEVTGRMAVVLPQGALFRKGVEGEIRRKLLEMDLIEGVIGLAPNLFYGTGLAACILLLRKRKPAERKRKVMIADASSL
FRRGRAQNYLEPEHGAEILGWYQAFIDVQDRVRIVSTDEIKAEDWTLNISRYVLPPLNDDIPPLPQAIAEFKSALERCRE
AETRLEQLMTDGGWLQ

Sequences:

>Translated_496_residues
MTLLPLSQLENHLWESANILRGPVDAADFKTYIFPLLFFKRICDVWDEEYQEIAEEMGDPELAMFPESHRFQVPEGCHWR
DIRETPVNVGNALQRALREIEKANPDTLYAVFGDAQWTNKDRLTDALLKDLIEHFSRLPLGNRNVASDVLGDAYEYLIKK
FADATNKKAGEFYTPRSVVRLMVDMLDPKEGDSIYDPACGTGGMLLAALQHVHELHGDTKLLWGKLFGQEKNLTTSAIAR
MNLFLHGIEDFQIVRGDTLRNPAFFEGDRLATFDCVIANPPFSLEKWGEEVWLNDPFGRNFAGLPPSSSGDFAWVQHMVK
SMAEVTGRMAVVLPQGALFRKGVEGEIRRKLLEMDLIEGVIGLAPNLFYGTGLAACILLLRKRKPAERKRKVMIADASSL
FRRGRAQNYLEPEHGAEILGWYQAFIDVQDRVRIVSTDEIKAEDWTLNISRYVLPPLNDDIPPLPQAIAEFKSALERCRE
AETRLEQLMTDGGWLQ
>Mature_495_residues
TLLPLSQLENHLWESANILRGPVDAADFKTYIFPLLFFKRICDVWDEEYQEIAEEMGDPELAMFPESHRFQVPEGCHWRD
IRETPVNVGNALQRALREIEKANPDTLYAVFGDAQWTNKDRLTDALLKDLIEHFSRLPLGNRNVASDVLGDAYEYLIKKF
ADATNKKAGEFYTPRSVVRLMVDMLDPKEGDSIYDPACGTGGMLLAALQHVHELHGDTKLLWGKLFGQEKNLTTSAIARM
NLFLHGIEDFQIVRGDTLRNPAFFEGDRLATFDCVIANPPFSLEKWGEEVWLNDPFGRNFAGLPPSSSGDFAWVQHMVKS
MAEVTGRMAVVLPQGALFRKGVEGEIRRKLLEMDLIEGVIGLAPNLFYGTGLAACILLLRKRKPAERKRKVMIADASSLF
RRGRAQNYLEPEHGAEILGWYQAFIDVQDRVRIVSTDEIKAEDWTLNISRYVLPPLNDDIPPLPQAIAEFKSALERCREA
ETRLEQLMTDGGWLQ

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=389, Percent_Identity=26.4781491002571, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 56238; Mature: 56107

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLPLSQLENHLWESANILRGPVDAADFKTYIFPLLFFKRICDVWDEEYQEIAEEMGDP
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ELAMFPESHRFQVPEGCHWRDIRETPVNVGNALQRALREIEKANPDTLYAVFGDAQWTNK
CEEECCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCH
DRLTDALLKDLIEHFSRLPLGNRNVASDVLGDAYEYLIKKFADATNKKAGEFYTPRSVVR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LMVDMLDPKEGDSIYDPACGTGGMLLAALQHVHELHGDTKLLWGKLFGQEKNLTTSAIAR
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHH
MNLFLHGIEDFQIVRGDTLRNPAFFEGDRLATFDCVIANPPFSLEKWGEEVWLNDPFGRN
HHHHHHCCCHHEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHCCCCEECCCCCCCC
FAGLPPSSSGDFAWVQHMVKSMAEVTGRMAVVLPQGALFRKGVEGEIRRKLLEMDLIEGV
CCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHH
IGLAPNLFYGTGLAACILLLRKRKPAERKRKVMIADASSLFRRGRAQNYLEPEHGAEILG
HHHCCCHHHHHHHHHHHHHHHCCCCHHHHHEEEEECHHHHHHCCCCCCCCCCHHHHHHHH
WYQAFIDVQDRVRIVSTDEIKAEDWTLNISRYVLPPLNDDIPPLPQAIAEFKSALERCRE
HHHHHHHHHHCEEEEECCCCCCCCEEEEEHHEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AETRLEQLMTDGGWLQ
HHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TLLPLSQLENHLWESANILRGPVDAADFKTYIFPLLFFKRICDVWDEEYQEIAEEMGDP
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ELAMFPESHRFQVPEGCHWRDIRETPVNVGNALQRALREIEKANPDTLYAVFGDAQWTNK
CEEECCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCH
DRLTDALLKDLIEHFSRLPLGNRNVASDVLGDAYEYLIKKFADATNKKAGEFYTPRSVVR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LMVDMLDPKEGDSIYDPACGTGGMLLAALQHVHELHGDTKLLWGKLFGQEKNLTTSAIAR
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHH
MNLFLHGIEDFQIVRGDTLRNPAFFEGDRLATFDCVIANPPFSLEKWGEEVWLNDPFGRN
HHHHHHCCCHHEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHCCCCEECCCCCCCC
FAGLPPSSSGDFAWVQHMVKSMAEVTGRMAVVLPQGALFRKGVEGEIRRKLLEMDLIEGV
CCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHH
IGLAPNLFYGTGLAACILLLRKRKPAERKRKVMIADASSLFRRGRAQNYLEPEHGAEILG
HHHCCCHHHHHHHHHHHHHHHCCCCHHHHHEEEEECHHHHHHCCCCCCCCCCHHHHHHHH
WYQAFIDVQDRVRIVSTDEIKAEDWTLNISRYVLPPLNDDIPPLPQAIAEFKSALERCRE
HHHHHHHHHHCEEEEECCCCCCCCEEEEEHHEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AETRLEQLMTDGGWLQ
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]