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The map label for this gene is hsdM [C]

Identifier: 189423916

GI number: 189423916

Start: 873973

End: 875451

Strand: Reverse

Name: hsdM [C]

Synonym: Glov_0849

Alternate gene names: 189423916

Gene position: 875451-873973 (Counterclockwise)

Preceding gene: 189423917

Following gene: 189423915

Centisome position: 22.35

GC content: 56.66

Gene sequence:

>1479_bases
ATGAGCTCGCGCATCTCTCAACAGGAATTGGAATCCTACCTCTGGGGTGCGGCAACGCTCCTGCGCGGACTGATCGACGC
CGGCGACTACAAGCAGTTCATCTTTCCATTGCTGTTCTTCAAGCGCGTTTCCGACGTGTACGACGAAGAGTACCAGCAGG
CAATGGACGAATCCGGCGGCGACTTTGCCGAGAATCACCGCTTTCAGATACCAGCGGGTTTCCATTGGAGCGATGTCCGC
CAGACCCCGAAAAATGTCGGTATGACCATTCAGACCGCCATGCGGGCCATCGAGGCGGCCAACCCCGACCAGTTGACCGG
CATCTTTGGCGACGCCCCTTGGACCAATAAGGAACGGTTGCCGGATGAGACCCTGAAGGATCTGATCGAGCACTTTTCGA
CCCAGACACTCTCGGTCGCCAACGTACCGGAAGATGAATTGGGCAATGCCTATGAGTTCCTGATCAAGAAGTTCGCCGAT
GACTCCGGCCATACGGCGGCCGAGTTCTACACGAACCGCACGGTCGTCCATCTGATGACGCAACTGCTGGACCCGCAACC
GGGAGAGTCGATCTACGATCCCACCTGCGGCACTGGCGGGATGCTCCTGTCGGCCCTGGCCGAGGTAAAGCGTACCGGCG
GCGAATACCGCACCCTCAAGCTTTATGGGCAGGAACGCAACCTGATGACCTCCGGTATTGCCCGGATGAATCTCTTCCTG
CATGGGATCGAAGATTTTCAGATCGCGCGAGGTGACACCCTGGCAGAGCCGAAGCTGATCGAAGGGGACCGGCTCAAGCA
GTTTGATGTGATCCTGGCCAACCCGCCGTACTCCATCAAGCAGTGGGACCGCCCAGCCTTCGAGTCTGATAAATGGGGAA
GGAATTTTCTCGGTACACCGCCGCAGGGACGTGCTGATTATGCCTTCTTCCAGCATATCCTGAAAAGCCTGACCAAGAAG
GGTCGCTGCGCCATCCTCTGGCCGCATGGGGTGCTGTTCCGCAATGAAGAGCAAGAGATGCGGGCTAAGATGATCGCCCA
GGACCTGGTAGAGGCGGTCATCGGCTTGGGACCGAACCTCTTTTACAACTCGCCGATGGAATCGTGCGTTGTTGTCTGCC
GTCGCAACAAGACAGGGGAGCGCAAGGGCAAGGTGCTCTTTATCGACGCTCTCAACGAAGTCACCCGTGAGCGGGCGCAG
AGTTTCCTCAAGCCCGAGCATCAGGACCGGATTCTGGCGGCTTTCAGAAATTTCCAGGACGATGCCGGTTTTGCCAAGGT
AGCCACCCTTGAGGAGATCGCCGCCAACGGTTCAAACCTGTCGATTCCGTTGTATGTGAAGCGGAATAATGGTGGTAGCG
TCTCCATCGGTGAAACACAAAGCCTGGAATCGGTATGGCAGCAGTGGCAGGATGAAAGACGTAACTTTTGGCAGAAGATG
GATTTACTTGTTGAAACCATCGAAAGAACAGCCCGTTGA

Upstream 100 bases:

>100_bases
CGTTGCCCCAGGCCATAGCAGAGTTCAAGTCGGCTCTCGAACGCTGTCGCGAGGCAGAGACCCGTCTGGAACAGTTAATG
ACGGATGGAGGCTGGTTGCA

Downstream 100 bases:

>100_bases
AAAAACATTTGGCTAAATTGATCAGCAACAAAGGGGAATAATTTTCATGCCGCTTAAAGTATTCTATAGCTGGCAGAGTG
ATGCCGATCCAAAAACAAAC

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSSRISQQELESYLWGAATLLRGLIDAGDYKQFIFPLLFFKRVSDVYDEEYQQAMDESGGDFAENHRFQIPAGFHWSDVR
QTPKNVGMTIQTAMRAIEAANPDQLTGIFGDAPWTNKERLPDETLKDLIEHFSTQTLSVANVPEDELGNAYEFLIKKFAD
DSGHTAAEFYTNRTVVHLMTQLLDPQPGESIYDPTCGTGGMLLSALAEVKRTGGEYRTLKLYGQERNLMTSGIARMNLFL
HGIEDFQIARGDTLAEPKLIEGDRLKQFDVILANPPYSIKQWDRPAFESDKWGRNFLGTPPQGRADYAFFQHILKSLTKK
GRCAILWPHGVLFRNEEQEMRAKMIAQDLVEAVIGLGPNLFYNSPMESCVVVCRRNKTGERKGKVLFIDALNEVTRERAQ
SFLKPEHQDRILAAFRNFQDDAGFAKVATLEEIAANGSNLSIPLYVKRNNGGSVSIGETQSLESVWQQWQDERRNFWQKM
DLLVETIERTAR

Sequences:

>Translated_492_residues
MSSRISQQELESYLWGAATLLRGLIDAGDYKQFIFPLLFFKRVSDVYDEEYQQAMDESGGDFAENHRFQIPAGFHWSDVR
QTPKNVGMTIQTAMRAIEAANPDQLTGIFGDAPWTNKERLPDETLKDLIEHFSTQTLSVANVPEDELGNAYEFLIKKFAD
DSGHTAAEFYTNRTVVHLMTQLLDPQPGESIYDPTCGTGGMLLSALAEVKRTGGEYRTLKLYGQERNLMTSGIARMNLFL
HGIEDFQIARGDTLAEPKLIEGDRLKQFDVILANPPYSIKQWDRPAFESDKWGRNFLGTPPQGRADYAFFQHILKSLTKK
GRCAILWPHGVLFRNEEQEMRAKMIAQDLVEAVIGLGPNLFYNSPMESCVVVCRRNKTGERKGKVLFIDALNEVTRERAQ
SFLKPEHQDRILAAFRNFQDDAGFAKVATLEEIAANGSNLSIPLYVKRNNGGSVSIGETQSLESVWQQWQDERRNFWQKM
DLLVETIERTAR
>Mature_491_residues
SSRISQQELESYLWGAATLLRGLIDAGDYKQFIFPLLFFKRVSDVYDEEYQQAMDESGGDFAENHRFQIPAGFHWSDVRQ
TPKNVGMTIQTAMRAIEAANPDQLTGIFGDAPWTNKERLPDETLKDLIEHFSTQTLSVANVPEDELGNAYEFLIKKFADD
SGHTAAEFYTNRTVVHLMTQLLDPQPGESIYDPTCGTGGMLLSALAEVKRTGGEYRTLKLYGQERNLMTSGIARMNLFLH
GIEDFQIARGDTLAEPKLIEGDRLKQFDVILANPPYSIKQWDRPAFESDKWGRNFLGTPPQGRADYAFFQHILKSLTKKG
RCAILWPHGVLFRNEEQEMRAKMIAQDLVEAVIGLGPNLFYNSPMESCVVVCRRNKTGERKGKVLFIDALNEVTRERAQS
FLKPEHQDRILAAFRNFQDDAGFAKVATLEEIAANGSNLSIPLYVKRNNGGSVSIGETQSLESVWQQWQDERRNFWQKMD
LLVETIERTAR

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=244, Percent_Identity=26.6393442622951, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 55855; Mature: 55724

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRISQQELESYLWGAATLLRGLIDAGDYKQFIFPLLFFKRVSDVYDEEYQQAMDESGG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DFAENHRFQIPAGFHWSDVRQTPKNVGMTIQTAMRAIEAANPDQLTGIFGDAPWTNKERL
CHHHCCCEECCCCCCHHHHHHCHHHCCCHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCC
PDETLKDLIEHFSTQTLSVANVPEDELGNAYEFLIKKFADDSGHTAAEFYTNRTVVHLMT
CHHHHHHHHHHHCCCEEEECCCCHHHHCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHH
QLLDPQPGESIYDPTCGTGGMLLSALAEVKRTGGEYRTLKLYGQERNLMTSGIARMNLFL
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
HGIEDFQIARGDTLAEPKLIEGDRLKQFDVILANPPYSIKQWDRPAFESDKWGRNFLGTP
HCCCHHEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCC
PQGRADYAFFQHILKSLTKKGRCAILWPHGVLFRNEEQEMRAKMIAQDLVEAVIGLGPNL
CCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCC
FYNSPMESCVVVCRRNKTGERKGKVLFIDALNEVTRERAQSFLKPEHQDRILAAFRNFQD
CCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
DAGFAKVATLEEIAANGSNLSIPLYVKRNNGGSVSIGETQSLESVWQQWQDERRNFWQKM
CCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
DLLVETIERTAR
HHHHHHHHHHCC
>Mature Secondary Structure 
SSRISQQELESYLWGAATLLRGLIDAGDYKQFIFPLLFFKRVSDVYDEEYQQAMDESGG
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DFAENHRFQIPAGFHWSDVRQTPKNVGMTIQTAMRAIEAANPDQLTGIFGDAPWTNKERL
CHHHCCCEECCCCCCHHHHHHCHHHCCCHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCC
PDETLKDLIEHFSTQTLSVANVPEDELGNAYEFLIKKFADDSGHTAAEFYTNRTVVHLMT
CHHHHHHHHHHHCCCEEEECCCCHHHHCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHH
QLLDPQPGESIYDPTCGTGGMLLSALAEVKRTGGEYRTLKLYGQERNLMTSGIARMNLFL
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
HGIEDFQIARGDTLAEPKLIEGDRLKQFDVILANPPYSIKQWDRPAFESDKWGRNFLGTP
HCCCHHEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCC
PQGRADYAFFQHILKSLTKKGRCAILWPHGVLFRNEEQEMRAKMIAQDLVEAVIGLGPNL
CCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCC
FYNSPMESCVVVCRRNKTGERKGKVLFIDALNEVTRERAQSFLKPEHQDRILAAFRNFQD
CCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
DAGFAKVATLEEIAANGSNLSIPLYVKRNNGGSVSIGETQSLESVWQQWQDERRNFWQKM
CCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
DLLVETIERTAR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]