Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 189423815

GI number: 189423815

Start: 756310

End: 757533

Strand: Reverse

Name: macB [H]

Synonym: Glov_0746

Alternate gene names: 189423815

Gene position: 757533-756310 (Counterclockwise)

Preceding gene: 189423816

Following gene: 189423814

Centisome position: 19.34

GC content: 58.99

Gene sequence:

>1224_bases
ATGATCCATCCCTCCCATCTGAAAGAGGCGGCCCGCAGCCTGTTGGCCTCAAAGCAGCGCACGGTCCTGGCCCTGATCGG
TATTGTGATCGGGATCGGCTCGGTGATCGCCATGGTCTCAGTGGGCAGGATCGTACAGGAAGAATCCCTGCGTCAGTTTA
AAGAGATGGGGACCGATATCCTGACCATCGACAAAGAGTTCGGCGGCGGTGGCCCACCCGGCATGCCGGGCGCACCTGCT
GCCGGTGCCGCAGCCAAGGCAGCGCTCAGGCTTGATACCATCCTGGCCATCCCCTCCCGCTGCCCCGGTATTGCGGCAGT
TGCCCCGTCGGTCAGAGGCAGTGGCGACATCAGCTTTACGGGCAAAAAACTGGAGCGCTGCAGCCCGATGGGGGTTACCG
CATCATTCCTGAATATCAACAAGCTGACCATGCGTGAAGGCCGCTTCCTGTCTGACCTGGATGAGCAAAGCCGCTACTGC
GTCATCGGCAGTCAGGTGGCTGCAGAGCTGCAAAAGCAGGGGGCATCCCAACTGCTCGGCTCAAAGATCAGGATCGGCGA
CAACCTGTTCACCGTTATCGGGGTTACCAGTGAGGTACCCCAGGGCGGTATGCGGCGCTTTGAACCCAATGAGATGATCT
ACGTGCATATCACCACCGGCCTGCGGGTCTTTACCAATGCCGAAATCCAATCCATCACTGCCAGGGTCAGTAATGGCACC
ACCAACAACGATGCCCGTGATCAGGTCATGGCCTACGTTGCCTCCCTGGGTAAGGGACAGGCGGTCAGAATAACCAGCCC
GGAAGAGATCATCGCCCAGATGGAAAAACAGATGCAGATGTTTACCCTGCTGCTGGGTGCCATCGGCAGCATCTCCCTGA
TTGTTGGCGGGGTCGGCGTCATGAACGTGATGCTGGTCTCGGTCACGGAACGCCGCCGGGAGATCGGTATCCGACGTGCC
CTAGGGGCCAAGCGGGGTGATATCCGTGGACAGTTCCTGATTGAATCGGTCATCCTGTCATTGATCGGCGGCCTGTTCGG
CATCATCTTCGGTATCGGCGCCTCCTGGCTGATCGCCCACTTTGCAAAATGGCAGTTTGCCCTCTCTTTCAGCGCCATCC
TGCTGGGGGTAGGTGTCTCCAATGCCGTGGGGATCTTCTTCGGCTACTATCCTGCCCGCCAGGCCTCCCTGCTTGATCCG
ATTGTAGCGCTCAAATCTGACTGA

Upstream 100 bases:

>100_bases
ATGCTGAAGAAGGAATTACCGTGGTCATCATCACCCACGATCCCGGCATTGCCCGTCAGTGCAAACGGGTGGCGGTCATG
AAGGACGGGGTGATTCTGTC

Downstream 100 bases:

>100_bases
AATCGCCATCTGCCACCGCCACCATTGTTGGCTGATCTTGGCAACCGTTGGCAGGCCGGCAGCGGCAACACACTGTAATG
GCTCGACGTTTTTTTGGCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MIHPSHLKEAARSLLASKQRTVLALIGIVIGIGSVIAMVSVGRIVQEESLRQFKEMGTDILTIDKEFGGGGPPGMPGAPA
AGAAAKAALRLDTILAIPSRCPGIAAVAPSVRGSGDISFTGKKLERCSPMGVTASFLNINKLTMREGRFLSDLDEQSRYC
VIGSQVAAELQKQGASQLLGSKIRIGDNLFTVIGVTSEVPQGGMRRFEPNEMIYVHITTGLRVFTNAEIQSITARVSNGT
TNNDARDQVMAYVASLGKGQAVRITSPEEIIAQMEKQMQMFTLLLGAIGSISLIVGGVGVMNVMLVSVTERRREIGIRRA
LGAKRGDIRGQFLIESVILSLIGGLFGIIFGIGASWLIAHFAKWQFALSFSAILLGVGVSNAVGIFFGYYPARQASLLDP
IVALKSD

Sequences:

>Translated_407_residues
MIHPSHLKEAARSLLASKQRTVLALIGIVIGIGSVIAMVSVGRIVQEESLRQFKEMGTDILTIDKEFGGGGPPGMPGAPA
AGAAAKAALRLDTILAIPSRCPGIAAVAPSVRGSGDISFTGKKLERCSPMGVTASFLNINKLTMREGRFLSDLDEQSRYC
VIGSQVAAELQKQGASQLLGSKIRIGDNLFTVIGVTSEVPQGGMRRFEPNEMIYVHITTGLRVFTNAEIQSITARVSNGT
TNNDARDQVMAYVASLGKGQAVRITSPEEIIAQMEKQMQMFTLLLGAIGSISLIVGGVGVMNVMLVSVTERRREIGIRRA
LGAKRGDIRGQFLIESVILSLIGGLFGIIFGIGASWLIAHFAKWQFALSFSAILLGVGVSNAVGIFFGYYPARQASLLDP
IVALKSD
>Mature_407_residues
MIHPSHLKEAARSLLASKQRTVLALIGIVIGIGSVIAMVSVGRIVQEESLRQFKEMGTDILTIDKEFGGGGPPGMPGAPA
AGAAAKAALRLDTILAIPSRCPGIAAVAPSVRGSGDISFTGKKLERCSPMGVTASFLNINKLTMREGRFLSDLDEQSRYC
VIGSQVAAELQKQGASQLLGSKIRIGDNLFTVIGVTSEVPQGGMRRFEPNEMIYVHITTGLRVFTNAEIQSITARVSNGT
TNNDARDQVMAYVASLGKGQAVRITSPEEIIAQMEKQMQMFTLLLGAIGSISLIVGGVGVMNVMLVSVTERRREIGIRRA
LGAKRGDIRGQFLIESVILSLIGGLFGIIFGIGASWLIAHFAKWQFALSFSAILLGVGVSNAVGIFFGYYPARQASLLDP
IVALKSD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=409, Percent_Identity=33.7408312958435, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43259; Mature: 43259

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHPSHLKEAARSLLASKQRTVLALIGIVIGIGSVIAMVSVGRIVQEESLRQFKEMGTDI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTIDKEFGGGGPPGMPGAPAAGAAAKAALRLDTILAIPSRCPGIAAVAPSVRGSGDISFT
EEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEC
GKKLERCSPMGVTASFLNINKLTMREGRFLSDLDEQSRYCVIGSQVAAELQKQGASQLLG
CHHHHCCCCCCCCHHHHCCCHHHHHCCCHHHHHHCCCCEEEEHHHHHHHHHHCCHHHHHC
SKIRIGDNLFTVIGVTSEVPQGGMRRFEPNEMIYVHITTGLRVFTNAEIQSITARVSNGT
CCEEECCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCHHHHHHHHHCCCC
TNNDARDQVMAYVASLGKGQAVRITSPEEIIAQMEKQMQMFTLLLGAIGSISLIVGGVGV
CCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNVMLVSVTERRREIGIRRALGAKRGDIRGQFLIESVILSLIGGLFGIIFGIGASWLIAH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAKWQFALSFSAILLGVGVSNAVGIFFGYYPARQASLLDPIVALKSD
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIHPSHLKEAARSLLASKQRTVLALIGIVIGIGSVIAMVSVGRIVQEESLRQFKEMGTDI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTIDKEFGGGGPPGMPGAPAAGAAAKAALRLDTILAIPSRCPGIAAVAPSVRGSGDISFT
EEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEC
GKKLERCSPMGVTASFLNINKLTMREGRFLSDLDEQSRYCVIGSQVAAELQKQGASQLLG
CHHHHCCCCCCCCHHHHCCCHHHHHCCCHHHHHHCCCCEEEEHHHHHHHHHHCCHHHHHC
SKIRIGDNLFTVIGVTSEVPQGGMRRFEPNEMIYVHITTGLRVFTNAEIQSITARVSNGT
CCEEECCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCHHHHHHHHHCCCC
TNNDARDQVMAYVASLGKGQAVRITSPEEIIAQMEKQMQMFTLLLGAIGSISLIVGGVGV
CCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNVMLVSVTERRREIGIRRALGAKRGDIRGQFLIESVILSLIGGLFGIIFGIGASWLIAH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAKWQFALSFSAILLGVGVSNAVGIFFGYYPARQASLLDPIVALKSD
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA