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The map label for this gene is yckA [H]

Identifier: 189423808

GI number: 189423808

Start: 750404

End: 751951

Strand: Reverse

Name: yckA [H]

Synonym: Glov_0739

Alternate gene names: 189423808

Gene position: 751951-750404 (Counterclockwise)

Preceding gene: 189423809

Following gene: 189423807

Centisome position: 19.19

GC content: 56.65

Gene sequence:

>1548_bases
ATGAACAAACCGATGCGGGTCACCTCATTGCTTATCTATCTGGCCGTGCTGTTCCTATGTACCGCAGCAGGCGGCTGCAA
CAGCAACCAGCTGCCCACCTCCGGCTCCCGCAGCATGCTGGCAACCGCCAACGACCTGCAGGACAAGCGGATTGCCGTGC
TGCAGGGTTCCACCCACGAAATGTACGCGACAAGGCACTATCCCGGGGCCACGGTGCTGCAGTACAAATCCGTCTCCGAC
ATGCTGCTGGCATTAAAGAGCGGCAAGGCAGACGCCGCCATCTACAGCCGCGATGAGCTGATGGAATATATGCGGGACAA
CGATGAATTCGGATTTGTGGGAGGGCCCCTGTACCGCACGCCGATCTCCATTGCCTTTCATCAACAGGATGCCGGGCTGC
TCCTCTCTTTCAACCGTTTCCTGCAGCAGATCCGCACGGACGGCACCTATGACGGCATGCTCAAACGCTGGATGCAGCAG
GGCGCTGTCGGGATGCCGAAGCTGACCGCCGCCGGAACCGGCAAACCTCTGGTGGTGGGGATTCTAAGCGACAACGGGCT
GCCCTTTATCGTTATGAAAGAGAACCGGTTGATCGGTTTTAATATCGAGCTGATGGAGCGTTTCGGTGCCTTCTGCAACC
GCAGCATCAAATACGCGGACATAGAGTTCGGCAGTCAGATTGCCGCCCTGGCAGGCCATAAGATCGATATGATCGCCACG
CCCCTGGCCATCACGGAAGAACGCAAGAAACGGGTCGCCTTTTCCGCTCCTTATTACACGGTCGATTCACTGGCCTTTGC
CCTGAAGAAGAACATCGCAACCAACAAAAGTTTAACACCATCCGCCCCCTCCTTCCTCAGCAAGCTTGTCACCAGTTTTC
AGAGCAACATCATCCATGAGAGGCGGTATCTGCTGATCCTGGACGGTCTCAAGACCACCGTGGTCATCTCGGTCTTCGCC
ACCCTCTTCGGCACCCTGCTGGGGGCGCTGATCTGCTTCATGCGGATGGCAAAGAGCAGGCTGCTCTCTGCCCCTGCCAG
GCTCTACATCGCCATCCTGCGGGGCACACCGGTACTGGTGCTGTTGATGCTGATCTTCTATGTCGTCTTTGCCTCGATCA
ACATCAACCCGGTCATTGTGGCGGTGATCGCCTTTGGCATGAACTTCGGCGCCTACACCGCCGAGATCTTCAGGACCGGC
ATTGAAGGGGTGGAAAAGGGACAGACCGAGGCTGGTATCTCTTTGGGCTTCACCAGGACCAGCACCTTCCTGCATATTGT
GCTGCCCCAGATGGTGCGGCGGATCCTGCCGGTCTACAAAGGCGAGTTCATCTCCCTGGTCAAGATGACCTCCATTGTCG
GCTACATCGCGGTACAGGATCTGACCAAGGCCAGCGACATCATCAGAAGCCGCACCTTTGACGCCTTCTTTCCCCTGGTC
ATGGTGGCCATCCTCTACTTCCTGATCTCATGGACACTGATGCAATCCCTTGAGTACCTGGAACGGATCACTGATCCCAA
ATACAAAAAGAGAAAGGCAGGCAGGTAA

Upstream 100 bases:

>100_bases
AGCATTGGTCAGGGAATAGTGTTGCCGGAGCTGCCTCTGAGACTGAGCAGGATCAAACGGGGCAGCTCCGCACCATTTTA
ATACAATACAGGCAGGATCA

Downstream 100 bases:

>100_bases
GCAACGCTTACGATTCAGCATATGACGACCAGTGTAACAAGAAAGGGGCAAAACTATGAAAATGACAGCATGCATCATCT
TTGTAGCCGTACTGATTGCC

Product: polar amino acid ABC transporter inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MNKPMRVTSLLIYLAVLFLCTAAGGCNSNQLPTSGSRSMLATANDLQDKRIAVLQGSTHEMYATRHYPGATVLQYKSVSD
MLLALKSGKADAAIYSRDELMEYMRDNDEFGFVGGPLYRTPISIAFHQQDAGLLLSFNRFLQQIRTDGTYDGMLKRWMQQ
GAVGMPKLTAAGTGKPLVVGILSDNGLPFIVMKENRLIGFNIELMERFGAFCNRSIKYADIEFGSQIAALAGHKIDMIAT
PLAITEERKKRVAFSAPYYTVDSLAFALKKNIATNKSLTPSAPSFLSKLVTSFQSNIIHERRYLLILDGLKTTVVISVFA
TLFGTLLGALICFMRMAKSRLLSAPARLYIAILRGTPVLVLLMLIFYVVFASININPVIVAVIAFGMNFGAYTAEIFRTG
IEGVEKGQTEAGISLGFTRTSTFLHIVLPQMVRRILPVYKGEFISLVKMTSIVGYIAVQDLTKASDIIRSRTFDAFFPLV
MVAILYFLISWTLMQSLEYLERITDPKYKKRKAGR

Sequences:

>Translated_515_residues
MNKPMRVTSLLIYLAVLFLCTAAGGCNSNQLPTSGSRSMLATANDLQDKRIAVLQGSTHEMYATRHYPGATVLQYKSVSD
MLLALKSGKADAAIYSRDELMEYMRDNDEFGFVGGPLYRTPISIAFHQQDAGLLLSFNRFLQQIRTDGTYDGMLKRWMQQ
GAVGMPKLTAAGTGKPLVVGILSDNGLPFIVMKENRLIGFNIELMERFGAFCNRSIKYADIEFGSQIAALAGHKIDMIAT
PLAITEERKKRVAFSAPYYTVDSLAFALKKNIATNKSLTPSAPSFLSKLVTSFQSNIIHERRYLLILDGLKTTVVISVFA
TLFGTLLGALICFMRMAKSRLLSAPARLYIAILRGTPVLVLLMLIFYVVFASININPVIVAVIAFGMNFGAYTAEIFRTG
IEGVEKGQTEAGISLGFTRTSTFLHIVLPQMVRRILPVYKGEFISLVKMTSIVGYIAVQDLTKASDIIRSRTFDAFFPLV
MVAILYFLISWTLMQSLEYLERITDPKYKKRKAGR
>Mature_515_residues
MNKPMRVTSLLIYLAVLFLCTAAGGCNSNQLPTSGSRSMLATANDLQDKRIAVLQGSTHEMYATRHYPGATVLQYKSVSD
MLLALKSGKADAAIYSRDELMEYMRDNDEFGFVGGPLYRTPISIAFHQQDAGLLLSFNRFLQQIRTDGTYDGMLKRWMQQ
GAVGMPKLTAAGTGKPLVVGILSDNGLPFIVMKENRLIGFNIELMERFGAFCNRSIKYADIEFGSQIAALAGHKIDMIAT
PLAITEERKKRVAFSAPYYTVDSLAFALKKNIATNKSLTPSAPSFLSKLVTSFQSNIIHERRYLLILDGLKTTVVISVFA
TLFGTLLGALICFMRMAKSRLLSAPARLYIAILRGTPVLVLLMLIFYVVFASININPVIVAVIAFGMNFGAYTAEIFRTG
IEGVEKGQTEAGISLGFTRTSTFLHIVLPQMVRRILPVYKGEFISLVKMTSIVGYIAVQDLTKASDIIRSRTFDAFFPLV
MVAILYFLISWTLMQSLEYLERITDPKYKKRKAGR

Specific function: Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=194, Percent_Identity=35.0515463917526, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787030, Length=201, Percent_Identity=34.3283582089552, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788646, Length=210, Percent_Identity=27.6190476190476, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786873, Length=220, Percent_Identity=30.4545454545455, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787087, Length=203, Percent_Identity=26.6009852216749, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788645, Length=225, Percent_Identity=28.8888888888889, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787086, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786874, Length=212, Percent_Identity=23.1132075471698, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787088, Length=131, Percent_Identity=25.1908396946565, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57146; Mature: 57146

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPMRVTSLLIYLAVLFLCTAAGGCNSNQLPTSGSRSMLATANDLQDKRIAVLQGSTHE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCHH
MYATRHYPGATVLQYKSVSDMLLALKSGKADAAIYSRDELMEYMRDNDEFGFVGGPLYRT
EEEEECCCCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHC
PISIAFHQQDAGLLLSFNRFLQQIRTDGTYDGMLKRWMQQGAVGMPKLTAAGTGKPLVVG
CEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEE
ILSDNGLPFIVMKENRLIGFNIELMERFGAFCNRSIKYADIEFGSQIAALAGHKIDMIAT
EECCCCCEEEEEECCEEEECHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCHHHCC
PLAITEERKKRVAFSAPYYTVDSLAFALKKNIATNKSLTPSAPSFLSKLVTSFQSNIIHE
CHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHC
RRYLLILDGLKTTVVISVFATLFGTLLGALICFMRMAKSRLLSAPARLYIAILRGTPVLV
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHCCCHHHH
LLMLIFYVVFASININPVIVAVIAFGMNFGAYTAEIFRTGIEGVEKGQTEAGISLGFTRT
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHH
STFLHIVLPQMVRRILPVYKGEFISLVKMTSIVGYIAVQDLTKASDIIRSRTFDAFFPLV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVAILYFLISWTLMQSLEYLERITDPKYKKRKAGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MNKPMRVTSLLIYLAVLFLCTAAGGCNSNQLPTSGSRSMLATANDLQDKRIAVLQGSTHE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCHH
MYATRHYPGATVLQYKSVSDMLLALKSGKADAAIYSRDELMEYMRDNDEFGFVGGPLYRT
EEEEECCCCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHC
PISIAFHQQDAGLLLSFNRFLQQIRTDGTYDGMLKRWMQQGAVGMPKLTAAGTGKPLVVG
CEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEE
ILSDNGLPFIVMKENRLIGFNIELMERFGAFCNRSIKYADIEFGSQIAALAGHKIDMIAT
EECCCCCEEEEEECCEEEECHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCHHHCC
PLAITEERKKRVAFSAPYYTVDSLAFALKKNIATNKSLTPSAPSFLSKLVTSFQSNIIHE
CHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHC
RRYLLILDGLKTTVVISVFATLFGTLLGALICFMRMAKSRLLSAPARLYIAILRGTPVLV
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHCCCHHHH
LLMLIFYVVFASININPVIVAVIAFGMNFGAYTAEIFRTGIEGVEKGQTEAGISLGFTRT
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHH
STFLHIVLPQMVRRILPVYKGEFISLVKMTSIVGYIAVQDLTKASDIIRSRTFDAFFPLV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVAILYFLISWTLMQSLEYLERITDPKYKKRKAGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377 [H]