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The map label for this gene is atoC [H]

Identifier: 189423806

GI number: 189423806

Start: 748822

End: 750048

Strand: Reverse

Name: atoC [H]

Synonym: Glov_0737

Alternate gene names: 189423806

Gene position: 750048-748822 (Counterclockwise)

Preceding gene: 189423807

Following gene: 189423805

Centisome position: 19.14

GC content: 60.47

Gene sequence:

>1227_bases
ATGCACGACACTCCACTCAACCAGCTGCTTGATCGCCTGATCGCCGTGGCCGAAGACCTCTCCATGGGGCGTTACGGTAA
ATACAACGACATTTTCGAACTGACCAAAAGCGGCCAGTACCCCCCCCTGATCGCCCGCTTTGCCGAGTCGTTCGGGATGA
TGGCGGTCAAGGTCGAGGCACGGGAATACCGGCTGGAGCAGATCATCGAAGAGCTTCGGGCAACCGAACTCCAACTGCGC
ACAGCCCGGGAACAGCTGGCCCGCGAGAACAGCAGCCTCAAAAAGAACCTGCGCCGTTCCTTTCCCTTTTCCTCCATCCT
CGGCACCAGCCCCCAGATCAGGGAGCTGATCGGCAAGGCAGAACGGATAGCCGATTCCCGCCTGTCGGTGATCATCACCG
GCGAGACCGGCACCGGCAAGGAACTGTTCGCCAAGGCGATCCACTTCAACAGCCCCCGCAGCGCCAAGCCGTTTGTGGCA
GTCAACTGTTCCGCCATCCCGGAGACCATCTTTGAAAGCGAAATGTTCGGCATTGAAAAGGGGGTGGCCACCGGGGTCGA
GGCCCGCATCGGCAAGATCCAGCAGGCGCAAGGCGGCACCCTGTTTCTGGACGAGGTGGGGGAGATGCCGTTGCAACTGC
AGGCCAAACTTTTGCGGGTGCTGGAAGAGCGGACCCTGGAACGGGTCGGCAGCCGGACCGCCATCCCGGTTGATCTGAGG
ATCATTGCCGCTACCAACCGCGATTTGACCAAAGAGATTGCCAAAGGCAGCTTCCGGGAGGATCTCTACTACCGCCTGAA
CGGCGTTACCCTGCGGATTCCGCCCCTGCGGGAACGTAAAGGCGACATTGACCTGATTGCACGCCAATTTCTGGAGAAGT
GGGGCCGCAGTTGCGGCAGGCCGCCGATGCGGATTGCCAAAGAGGCGCTGGAACGGCTGCGCGGCTATACCTGGCCCGGC
AACGTGCGTGAACTGGATAACGAAATTGAGCGGGCTGTGGCACTGGCCTACGGCGACACCATTACCATGACCGACCTTTC
TGATCCGCTGCAGCAGCAGACCACTCTACCAGCAGCCGGGGGAAAATCACTGCTGAAGGATTCAGAGAAACAGCTGATCG
AGCAGGCGCTGAAAGAGGCCAAAGGCAACAAGACCCAGGCAGCAGAACGGCTGGGAATGAGCCGCGAGGGGCTGCGCAAG
AAGCTGAAGCGGCTGGGCATGGAGTAG

Upstream 100 bases:

>100_bases
GCGAAGCGAGCTTGCCAGTGCCGGTAAGGCCTATGATGGCCAATCAGGCTGGTTTTGCTGGAACGGCACCTTAAAGTAAG
CCACAACACAAGGAGCCACC

Downstream 100 bases:

>100_bases
CGCCACCAGAGTTGGCGGCAACAGTTGTCGTATTGGCAAACACTCATTACCTAACATACTAAAATCACAACATTATATTT
TGGCATGCAATCTGCTGAAT

Product: sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MHDTPLNQLLDRLIAVAEDLSMGRYGKYNDIFELTKSGQYPPLIARFAESFGMMAVKVEAREYRLEQIIEELRATELQLR
TAREQLARENSSLKKNLRRSFPFSSILGTSPQIRELIGKAERIADSRLSVIITGETGTGKELFAKAIHFNSPRSAKPFVA
VNCSAIPETIFESEMFGIEKGVATGVEARIGKIQQAQGGTLFLDEVGEMPLQLQAKLLRVLEERTLERVGSRTAIPVDLR
IIAATNRDLTKEIAKGSFREDLYYRLNGVTLRIPPLRERKGDIDLIARQFLEKWGRSCGRPPMRIAKEALERLRGYTWPG
NVRELDNEIERAVALAYGDTITMTDLSDPLQQQTTLPAAGGKSLLKDSEKQLIEQALKEAKGNKTQAAERLGMSREGLRK
KLKRLGME

Sequences:

>Translated_408_residues
MHDTPLNQLLDRLIAVAEDLSMGRYGKYNDIFELTKSGQYPPLIARFAESFGMMAVKVEAREYRLEQIIEELRATELQLR
TAREQLARENSSLKKNLRRSFPFSSILGTSPQIRELIGKAERIADSRLSVIITGETGTGKELFAKAIHFNSPRSAKPFVA
VNCSAIPETIFESEMFGIEKGVATGVEARIGKIQQAQGGTLFLDEVGEMPLQLQAKLLRVLEERTLERVGSRTAIPVDLR
IIAATNRDLTKEIAKGSFREDLYYRLNGVTLRIPPLRERKGDIDLIARQFLEKWGRSCGRPPMRIAKEALERLRGYTWPG
NVRELDNEIERAVALAYGDTITMTDLSDPLQQQTTLPAAGGKSLLKDSEKQLIEQALKEAKGNKTQAAERLGMSREGLRK
KLKRLGME
>Mature_408_residues
MHDTPLNQLLDRLIAVAEDLSMGRYGKYNDIFELTKSGQYPPLIARFAESFGMMAVKVEAREYRLEQIIEELRATELQLR
TAREQLARENSSLKKNLRRSFPFSSILGTSPQIRELIGKAERIADSRLSVIITGETGTGKELFAKAIHFNSPRSAKPFVA
VNCSAIPETIFESEMFGIEKGVATGVEARIGKIQQAQGGTLFLDEVGEMPLQLQAKLLRVLEERTLERVGSRTAIPVDLR
IIAATNRDLTKEIAKGSFREDLYYRLNGVTLRIPPLRERKGDIDLIARQFLEKWGRSCGRPPMRIAKEALERLRGYTWPG
NVRELDNEIERAVALAYGDTITMTDLSDPLQQQTTLPAAGGKSLLKDSEKQLIEQALKEAKGNKTQAAERLGMSREGLRK
KLKRLGME

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=358, Percent_Identity=43.5754189944134, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI87082117, Length=344, Percent_Identity=43.8953488372093, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1789087, Length=336, Percent_Identity=45.5357142857143, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1790437, Length=303, Percent_Identity=44.8844884488449, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1790299, Length=341, Percent_Identity=40.7624633431085, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=43.7888198757764, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1788905, Length=303, Percent_Identity=45.8745874587459, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI87082152, Length=328, Percent_Identity=41.4634146341463, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1786524, Length=377, Percent_Identity=38.7267904509284, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1787583, Length=313, Percent_Identity=38.3386581469649, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87081872, Length=317, Percent_Identity=37.2239747634069, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87081858, Length=317, Percent_Identity=31.5457413249211, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789828, Length=338, Percent_Identity=31.9526627218935, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 45814; Mature: 45814

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDTPLNQLLDRLIAVAEDLSMGRYGKYNDIFELTKSGQYPPLIARFAESFGMMAVKVEA
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEHH
REYRLEQIIEELRATELQLRTAREQLARENSSLKKNLRRSFPFSSILGTSPQIRELIGKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHH
ERIADSRLSVIITGETGTGKELFAKAIHFNSPRSAKPFVAVNCSAIPETIFESEMFGIEK
HHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
GVATGVEARIGKIQQAQGGTLFLDEVGEMPLQLQAKLLRVLEERTLERVGSRTAIPVDLR
HHHHCHHHHHHHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
IIAATNRDLTKEIAKGSFREDLYYRLNGVTLRIPPLRERKGDIDLIARQFLEKWGRSCGR
EEEECCCHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
PPMRIAKEALERLRGYTWPGNVRELDNEIERAVALAYGDTITMTDLSDPLQQQTTLPAAG
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHCCCCCCC
GKSLLKDSEKQLIEQALKEAKGNKTQAAERLGMSREGLRKKLKRLGME
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MHDTPLNQLLDRLIAVAEDLSMGRYGKYNDIFELTKSGQYPPLIARFAESFGMMAVKVEA
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEHH
REYRLEQIIEELRATELQLRTAREQLARENSSLKKNLRRSFPFSSILGTSPQIRELIGKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHH
ERIADSRLSVIITGETGTGKELFAKAIHFNSPRSAKPFVAVNCSAIPETIFESEMFGIEK
HHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
GVATGVEARIGKIQQAQGGTLFLDEVGEMPLQLQAKLLRVLEERTLERVGSRTAIPVDLR
HHHHCHHHHHHHHHHCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
IIAATNRDLTKEIAKGSFREDLYYRLNGVTLRIPPLRERKGDIDLIARQFLEKWGRSCGR
EEEECCCHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
PPMRIAKEALERLRGYTWPGNVRELDNEIERAVALAYGDTITMTDLSDPLQQQTTLPAAG
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHCCCCCCC
GKSLLKDSEKQLIEQALKEAKGNKTQAAERLGMSREGLRKKLKRLGME
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]