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The map label for this gene is degP [H]

Identifier: 189423555

GI number: 189423555

Start: 460420

End: 461586

Strand: Reverse

Name: degP [H]

Synonym: Glov_0484

Alternate gene names: 189423555

Gene position: 461586-460420 (Counterclockwise)

Preceding gene: 189423557

Following gene: 189423554

Centisome position: 11.78

GC content: 60.33

Gene sequence:

>1167_bases
ATGATGCGCACACCGATCCGACTGTTGTTGCTTATTTCCGCCGCGGTCATCCTTGGCTCCTGTTCCTCCTCAAAGGACGA
GCCGCTCTTTTTCAAATCAAAACGTCCTGCTGCCGAAGCTGAACCGCCGGTCAAGGATGTACCGGCCGATATCCTCTCCA
CCCAGCGCGCCTTCAGCCAGGTCTCAAAAAAAGTGACCCCCATTGTGGTCAACATCTCAACCATCAGCCGCAAAAAGCTG
GTACGCCCGTTCCCGGACCTGCCGCCCCTGTTTGAGGAGTTTTTTGGCGGCGGCCCCCAGACCCGGCGTGACAAGAGTCT
GGGCTCCGGCTTTATCATCAGCCGGGACGGCTTTATTGTCACCAACGAGCATGTGGTCCGGGATGCTGAAAGTATCCGGG
TCAAGCTCTCCAACGACAAGGTCTATGAGGCCAGGGTCGTGGGCGGTGACCCCAAGACCGACATTGCCGTGATCAAGATT
GATGCCGGTGACCTGCCGGTGGCAGTGCTGGGAGATTCGGATCGGCTTGAGGTGGGTCAATGGGCCATTGCCATTGGCAA
TCCGTTTGGCCTGGAACGTTCCATGACCGTGGGGATCATCTCTGCCACTGGCCGTTCCAATGTGGGGATCGAGAGCATCG
AGAATTTCATCCAGACCGATGCCTCCATCAACCCCGGCAACTCCGGCGGACCGCTGCTGAACATCCACGGCGAGGTGGTG
GGAATCAACACCGCCATTGTGGCGGCCGGGCAGGGGATCGGTTTTGCCATCCCGACCAACATGGCCCGCCCGATCATCAG
CCAGCTGGTTGAAAAGGGCAAGGTAACCCGGGCCTGGCTGGGGGTCAGCATCAAACCGGTCACTGAAGAAGAGGCCCGTT
CCCTGGGGCTCAGCAAGCCTGCCGGCGTCGTAATTGCCGCTGTGCAGGGTGATGGCCCGGCTGCCAAGGGGGGCATACAG
GCAGGTGATCTGGTCGTCGCATTTGGCTCTACCGAGGTACGGGACCCCTCCCATCTGCAGCAGCTGGTGGCGGTCACCCG
GATCGGCGCTGCAGTGCCGGTAGTGGTTCTGCGCGGGGGACGTAAAATAACGGTCACGGTCAGGCCCGGTAATGCCGATA
GTGCTTCCTCGGCGCGGCGTATTGAGCAGGAAGACAGCGCACGCTAA

Upstream 100 bases:

>100_bases
GGGCGAAGCAGTTGACAGCCTGTTGCCTTTGGGCTAGCCTAACCTCGTTCTATGGTGCAACGATGCTCCTGTATACAATC
CATTTAACAAGGTTGTCAAT

Downstream 100 bases:

>100_bases
GTCAATTGATTTACTTTGCGGCAAATCTGAGCTAGAGTGTTGAGAATGCTTGGATGACTTCCCCCCGAAAGGAAGAACCA
TGAATATCATCACCACCAAG

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MMRTPIRLLLLISAAVILGSCSSSKDEPLFFKSKRPAAEAEPPVKDVPADILSTQRAFSQVSKKVTPIVVNISTISRKKL
VRPFPDLPPLFEEFFGGGPQTRRDKSLGSGFIISRDGFIVTNEHVVRDAESIRVKLSNDKVYEARVVGGDPKTDIAVIKI
DAGDLPVAVLGDSDRLEVGQWAIAIGNPFGLERSMTVGIISATGRSNVGIESIENFIQTDASINPGNSGGPLLNIHGEVV
GINTAIVAAGQGIGFAIPTNMARPIISQLVEKGKVTRAWLGVSIKPVTEEEARSLGLSKPAGVVIAAVQGDGPAAKGGIQ
AGDLVVAFGSTEVRDPSHLQQLVAVTRIGAAVPVVVLRGGRKITVTVRPGNADSASSARRIEQEDSAR

Sequences:

>Translated_388_residues
MMRTPIRLLLLISAAVILGSCSSSKDEPLFFKSKRPAAEAEPPVKDVPADILSTQRAFSQVSKKVTPIVVNISTISRKKL
VRPFPDLPPLFEEFFGGGPQTRRDKSLGSGFIISRDGFIVTNEHVVRDAESIRVKLSNDKVYEARVVGGDPKTDIAVIKI
DAGDLPVAVLGDSDRLEVGQWAIAIGNPFGLERSMTVGIISATGRSNVGIESIENFIQTDASINPGNSGGPLLNIHGEVV
GINTAIVAAGQGIGFAIPTNMARPIISQLVEKGKVTRAWLGVSIKPVTEEEARSLGLSKPAGVVIAAVQGDGPAAKGGIQ
AGDLVVAFGSTEVRDPSHLQQLVAVTRIGAAVPVVVLRGGRKITVTVRPGNADSASSARRIEQEDSAR
>Mature_388_residues
MMRTPIRLLLLISAAVILGSCSSSKDEPLFFKSKRPAAEAEPPVKDVPADILSTQRAFSQVSKKVTPIVVNISTISRKKL
VRPFPDLPPLFEEFFGGGPQTRRDKSLGSGFIISRDGFIVTNEHVVRDAESIRVKLSNDKVYEARVVGGDPKTDIAVIKI
DAGDLPVAVLGDSDRLEVGQWAIAIGNPFGLERSMTVGIISATGRSNVGIESIENFIQTDASINPGNSGGPLLNIHGEVV
GINTAIVAAGQGIGFAIPTNMARPIISQLVEKGKVTRAWLGVSIKPVTEEEARSLGLSKPAGVVIAAVQGDGPAAKGGIQ
AGDLVVAFGSTEVRDPSHLQQLVAVTRIGAAVPVVVLRGGRKITVTVRPGNADSASSARRIEQEDSAR

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=298, Percent_Identity=37.5838926174497, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI22129776, Length=303, Percent_Identity=36.6336633663366, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI24308541, Length=277, Percent_Identity=36.101083032491, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI7019477, Length=280, Percent_Identity=36.0714285714286, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1786356, Length=336, Percent_Identity=38.9880952380952, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI1789629, Length=316, Percent_Identity=38.9240506329114, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789630, Length=270, Percent_Identity=40.7407407407407, Blast_Score=194, Evalue=8e-51,
Organism=Drosophila melanogaster, GI24646839, Length=298, Percent_Identity=33.5570469798658, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 40836; Mature: 40836

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRTPIRLLLLISAAVILGSCSSSKDEPLFFKSKRPAAEAEPPVKDVPADILSTQRAFSQ
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHH
VSKKVTPIVVNISTISRKKLVRPFPDLPPLFEEFFGGGPQTRRDKSLGSGFIISRDGFIV
HHHCCCEEEEEEEHHCHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEE
TNEHVVRDAESIRVKLSNDKVYEARVVGGDPKTDIAVIKIDAGDLPVAVLGDSDRLEVGQ
ECCHHHCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCEEECE
WAIAIGNPFGLERSMTVGIISATGRSNVGIESIENFIQTDASINPGNSGGPLLNIHGEVV
EEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCEEE
GINTAIVAAGQGIGFAIPTNMARPIISQLVEKGKVTRAWLGVSIKPVTEEEARSLGLSKP
EECEEEEEECCCCCEECCCHHHHHHHHHHHHCCCCEEEEECEEEECCCHHHHHHCCCCCC
AGVVIAAVQGDGPAAKGGIQAGDLVVAFGSTEVRDPSHLQQLVAVTRIGAAVPVVVLRGG
CCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECC
RKITVTVRPGNADSASSARRIEQEDSAR
CEEEEEEECCCCCCCHHHHHHCHHCCCC
>Mature Secondary Structure
MMRTPIRLLLLISAAVILGSCSSSKDEPLFFKSKRPAAEAEPPVKDVPADILSTQRAFSQ
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHH
VSKKVTPIVVNISTISRKKLVRPFPDLPPLFEEFFGGGPQTRRDKSLGSGFIISRDGFIV
HHHCCCEEEEEEEHHCHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEE
TNEHVVRDAESIRVKLSNDKVYEARVVGGDPKTDIAVIKIDAGDLPVAVLGDSDRLEVGQ
ECCHHHCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCEEECE
WAIAIGNPFGLERSMTVGIISATGRSNVGIESIENFIQTDASINPGNSGGPLLNIHGEVV
EEEEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCEEE
GINTAIVAAGQGIGFAIPTNMARPIISQLVEKGKVTRAWLGVSIKPVTEEEARSLGLSKP
EECEEEEEECCCCCEECCCHHHHHHHHHHHHCCCCEEEEECEEEECCCHHHHHHCCCCCC
AGVVIAAVQGDGPAAKGGIQAGDLVVAFGSTEVRDPSHLQQLVAVTRIGAAVPVVVLRGG
CCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECC
RKITVTVRPGNADSASSARRIEQEDSAR
CEEEEEEECCCCCCCHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]