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The map label for this gene is mtnN [H]

Identifier: 189423432

GI number: 189423432

Start: 330790

End: 331551

Strand: Reverse

Name: mtnN [H]

Synonym: Glov_0361

Alternate gene names: 189423432

Gene position: 331551-330790 (Counterclockwise)

Preceding gene: 189423434

Following gene: 189423429

Centisome position: 8.46

GC content: 61.55

Gene sequence:

>762_bases
ATGGATACGGTCAAGCATATCGGCATTATTGTGGCAATGCCCGAGGAACGGGTCGCTCTGGTCAAACGTCTGCAGCAGGT
CAAGCGACGCCTGATGGGGGGCATCCCCTTTTACCGCGGCATGCTGGCGGACCGCCTGGTCACGGTGGTTGAAGGTGGCA
TGGGAACGGCAGCTGCAGCCCTCGCAGCCCACCAGCTGATCAAGGCGGACCGGCCAAACCTGCTGCTGTCGGCCGGATTC
TGCGGTGCCGTACGCCCGGGGGCGCAGGTGGCCGATCTGGTACTCTGCAAACGGCTCTTCACTGACAACGAAAACGGCCT
GAACGAAGTAACCCTGCCGGGAAGTGAACTGATCACTGCACGGCTGTCTGCCGAATTGCAGCACAGAGGACTGCGGACCT
GGCAGGGCAGCTTCATTACCACCGGCAGGATCGTCACCAAAAGCGCCTGCGCCGGAACACTGCCCGACAACCTCCCGACC
CCGGTACTGGAGATGGAGAGTGCTGCCGTTGCCCAGGCAGCCACCGCAGCGGGAATCCCTTTTCTGGGGTTACGTGCCAT
CAGCGATGATGCTGCCGAAGAACTGGGGTTTTCACTGGATGAGCTGACCGATGAACAGTTAAGGATCAGCATTCCCCGCG
TACTCTTCACCTGCCTGAAAAAACCGCGCATCATCCCCCAGCTGGCCCGCTTGGCGGCCAACAGCGGCAGGGCCGGCAAA
AATCTCGGCCTGGCCCTGCAGCAGATCCTGCCGATGCTGTAG

Upstream 100 bases:

>100_bases
CTCCAGGAAGAACTTTTTTAATTACATGAATATGACCTGTTTGTCCAGAATTTTGATCAGGGGCTTTTCAGGGGCGACAA
ATGGAGGTACAGTACGCAGC

Downstream 100 bases:

>100_bases
TGAAAAGCGCAGTCAGCTGTTTTCAGATTGCCGATAAAGGCAAGATGGCTACCACCTGCCCAGCGGCGACCAGGGATAAT
CCTTGAGATGTTCCCGCAGT

Product: purine or other phosphorylase family 1

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MDTVKHIGIIVAMPEERVALVKRLQQVKRRLMGGIPFYRGMLADRLVTVVEGGMGTAAAALAAHQLIKADRPNLLLSAGF
CGAVRPGAQVADLVLCKRLFTDNENGLNEVTLPGSELITARLSAELQHRGLRTWQGSFITTGRIVTKSACAGTLPDNLPT
PVLEMESAAVAQAATAAGIPFLGLRAISDDAAEELGFSLDELTDEQLRISIPRVLFTCLKKPRIIPQLARLAANSGRAGK
NLGLALQQILPML

Sequences:

>Translated_253_residues
MDTVKHIGIIVAMPEERVALVKRLQQVKRRLMGGIPFYRGMLADRLVTVVEGGMGTAAAALAAHQLIKADRPNLLLSAGF
CGAVRPGAQVADLVLCKRLFTDNENGLNEVTLPGSELITARLSAELQHRGLRTWQGSFITTGRIVTKSACAGTLPDNLPT
PVLEMESAAVAQAATAAGIPFLGLRAISDDAAEELGFSLDELTDEQLRISIPRVLFTCLKKPRIIPQLARLAANSGRAGK
NLGLALQQILPML
>Mature_253_residues
MDTVKHIGIIVAMPEERVALVKRLQQVKRRLMGGIPFYRGMLADRLVTVVEGGMGTAAAALAAHQLIKADRPNLLLSAGF
CGAVRPGAQVADLVLCKRLFTDNENGLNEVTLPGSELITARLSAELQHRGLRTWQGSFITTGRIVTKSACAGTLPDNLPT
PVLEMESAAVAQAATAAGIPFLGLRAISDDAAEELGFSLDELTDEQLRISIPRVLFTCLKKPRIIPQLARLAANSGRAGK
NLGLALQQILPML

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=208, Percent_Identity=27.4038461538462, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 27020; Mature: 27020

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTVKHIGIIVAMPEERVALVKRLQQVKRRLMGGIPFYRGMLADRLVTVVEGGMGTAAAA
CCCHHHCEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHH
LAAHQLIKADRPNLLLSAGFCGAVRPGAQVADLVLCKRLFTDNENGLNEVTLPGSELITA
HHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHH
RLSAELQHRGLRTWQGSFITTGRIVTKSACAGTLPDNLPTPVLEMESAAVAQAATAAGIP
HHHHHHHHCCCHHHCCCEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
FLGLRAISDDAAEELGFSLDELTDEQLRISIPRVLFTCLKKPRIIPQLARLAANSGRAGK
HHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
NLGLALQQILPML
HHHHHHHHHHCCC
>Mature Secondary Structure
MDTVKHIGIIVAMPEERVALVKRLQQVKRRLMGGIPFYRGMLADRLVTVVEGGMGTAAAA
CCCHHHCEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHH
LAAHQLIKADRPNLLLSAGFCGAVRPGAQVADLVLCKRLFTDNENGLNEVTLPGSELITA
HHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHH
RLSAELQHRGLRTWQGSFITTGRIVTKSACAGTLPDNLPTPVLEMESAAVAQAATAAGIP
HHHHHHHHCCCHHHCCCEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
FLGLRAISDDAAEELGFSLDELTDEQLRISIPRVLFTCLKKPRIIPQLARLAANSGRAGK
HHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
NLGLALQQILPML
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA