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The map label for this gene is ttuB [H]

Identifier: 189354069

GI number: 189354069

Start: 2402056

End: 2403432

Strand: Reverse

Name: ttuB [H]

Synonym: BMULJ_05322

Alternate gene names: 189354069

Gene position: 2403432-2402056 (Counterclockwise)

Preceding gene: 189354070

Following gene: 189354068

Centisome position: 97.18

GC content: 71.17

Gene sequence:

>1377_bases
ATGACGACGACGCAGCACACGTCCGCGGCATCGGCCGCGGCCCCGTCCGGCCCGGCGGCAGCCGTCGACGAACGGCAACT
GATGGGACTGCTCACGCGCAGGCTCGTGCCGTTTCTCGCGCTGATCTACGTGGTCGCGTATGTCGACCGCACGGTGGTCG
GCTTCGCGAAGCTGCATATGAACGCGGCCGTCGGGCTCAGCGACGCGGCATACGGGCTCGGCGCGGGCCTGTTCTTCATC
GGCTACTTCCTGTGCGAAGTGCCGAGCAACCTCGCGCTCGGCCGCTTCGGTGCGCGCGTGTGGTTCGCGCGGATTCTCGC
GACGTGGGGCGTGATCACGATGGCGATGGCGCTGGTGCGCGGCCCCACGAGCTTCTACGTGCTGCGCTTTCTGCTCGGCG
CGGCGGAAGCCGGACTGTATCCGGGCATCCTCTATTTCCTGACGCAGTGGTTTCCGATGCGCGACCGCGCGCGCGTGATC
GGACTGCTCGTGCTTGCGCAGCCGGTCGCCGGCATCGTGACCGGCCCGCTCGCAGGCTGGCTGCTGTCGACGCACGGCCT
GTTCGGCCTGTCGAACTGGCAGACGCTGTTCGTCGCGAGCGGGCTGCCGGCCGTGCTGCTCGTGTGGCCGACGCTGCGCG
TGCTGCCCGAGTCGCCGGAGCGCGCGCGCTGGCTCGACGACGCGCAGCGCCGCTGGATCGCGCGCGAGCTCGCGGCCGAC
CGCGACACCTACCGGCCCGACGCGCATCGCAATCCGCTCGCGGCGCTGCGCGACCGGCGCGTGCTGCTGCTCGCGGCGCT
GTTCCTGCCGTTCCCGCTCTGCATCTACGGGCTGTCGCTCTGGCTGCCGACGATCATCAAGGCGTTCGGCACCGGCGACG
CGGCGACCGGGCTGCTGTCGGCCGTCCCGTACCTGTTCGCCGTGGTCGGGCTGCTCGTCGTGCCGCGCCATTCCGATCGG
ACGCGCGAGCGCTATGCGCACATCGTCGTCGTGTCGGCCGCGGCGGCGCTGACGATGGCGGCCAGCGCGTCGGTGCGGCA
GCCCGCGCTGCAGTTCCTGTTCATCTGCCTGACCGCGTTTTCGCTCTATTCGATTCAGGCCGTCGTGTGGGCGCTGCCCG
GCGAATTCCTGACGGGCACGAGCGCGGCGGTCGGCATCGCGGCGATCAACTCGCTCGCGAATCTCGGCGGCTACGTCGGG
CCGTACGGCATCGGCCTGATCAAGCAGGCGACCGGCAGTCTCGCTGCCGGCCTGTACTTCCTCGCGGCGACGCTGCTGTT
CGCCGTGCTGATCACGTTCGCGGTGCGCGCGGCGCTGCGTGCGCCGCAGCGCGCGGGCGACGCGCTCGCGCGCGAATCGC
GGCCGCTTTCCGGCTGA

Upstream 100 bases:

>100_bases
ACGAGGCACGAGGCACGAGGCGGCACGAGCGGCACGAGGCGGCACGACCTGAACGACACAGACCGGCGACGACGCCGGCA
CGCACATCGATGGAGACAGG

Downstream 100 bases:

>100_bases
CCGCCGTTTGACTGACGCAGGATCCGAACCATGACATCGAGCCGTACGCCGCGTTACCGCGGCATTTTCCCGGTCGTTCC
GACGACCTTCACCGAGACCG

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTTTQHTSAASAAAPSGPAAAVDERQLMGLLTRRLVPFLALIYVVAYVDRTVVGFAKLHMNAAVGLSDAAYGLGAGLFFI
GYFLCEVPSNLALGRFGARVWFARILATWGVITMAMALVRGPTSFYVLRFLLGAAEAGLYPGILYFLTQWFPMRDRARVI
GLLVLAQPVAGIVTGPLAGWLLSTHGLFGLSNWQTLFVASGLPAVLLVWPTLRVLPESPERARWLDDAQRRWIARELAAD
RDTYRPDAHRNPLAALRDRRVLLLAALFLPFPLCIYGLSLWLPTIIKAFGTGDAATGLLSAVPYLFAVVGLLVVPRHSDR
TRERYAHIVVVSAAAALTMAASASVRQPALQFLFICLTAFSLYSIQAVVWALPGEFLTGTSAAVGIAAINSLANLGGYVG
PYGIGLIKQATGSLAAGLYFLAATLLFAVLITFAVRAALRAPQRAGDALARESRPLSG

Sequences:

>Translated_458_residues
MTTTQHTSAASAAAPSGPAAAVDERQLMGLLTRRLVPFLALIYVVAYVDRTVVGFAKLHMNAAVGLSDAAYGLGAGLFFI
GYFLCEVPSNLALGRFGARVWFARILATWGVITMAMALVRGPTSFYVLRFLLGAAEAGLYPGILYFLTQWFPMRDRARVI
GLLVLAQPVAGIVTGPLAGWLLSTHGLFGLSNWQTLFVASGLPAVLLVWPTLRVLPESPERARWLDDAQRRWIARELAAD
RDTYRPDAHRNPLAALRDRRVLLLAALFLPFPLCIYGLSLWLPTIIKAFGTGDAATGLLSAVPYLFAVVGLLVVPRHSDR
TRERYAHIVVVSAAAALTMAASASVRQPALQFLFICLTAFSLYSIQAVVWALPGEFLTGTSAAVGIAAINSLANLGGYVG
PYGIGLIKQATGSLAAGLYFLAATLLFAVLITFAVRAALRAPQRAGDALARESRPLSG
>Mature_457_residues
TTTQHTSAASAAAPSGPAAAVDERQLMGLLTRRLVPFLALIYVVAYVDRTVVGFAKLHMNAAVGLSDAAYGLGAGLFFIG
YFLCEVPSNLALGRFGARVWFARILATWGVITMAMALVRGPTSFYVLRFLLGAAEAGLYPGILYFLTQWFPMRDRARVIG
LLVLAQPVAGIVTGPLAGWLLSTHGLFGLSNWQTLFVASGLPAVLLVWPTLRVLPESPERARWLDDAQRRWIARELAADR
DTYRPDAHRNPLAALRDRRVLLLAALFLPFPLCIYGLSLWLPTIIKAFGTGDAATGLLSAVPYLFAVVGLLVVPRHSDRT
RERYAHIVVVSAAAALTMAASASVRQPALQFLFICLTAFSLYSIQAVVWALPGEFLTGTSAAVGIAAINSLANLGGYVGP
YGIGLIKQATGSLAAGLYFLAATLLFAVLITFAVRAALRAPQRAGDALARESRPLSG

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=407, Percent_Identity=36.6093366093366, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1789152, Length=447, Percent_Identity=23.9373601789709, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082320, Length=421, Percent_Identity=24.2280285035629, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI2367379, Length=459, Percent_Identity=21.5686274509804, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789515, Length=444, Percent_Identity=22.2972972972973, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569727, Length=184, Percent_Identity=25, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=329, Percent_Identity=22.4924012158055, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49010; Mature: 48879

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTTQHTSAASAAAPSGPAAAVDERQLMGLLTRRLVPFLALIYVVAYVDRTVVGFAKLHM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]