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The map label for this gene is fadD [H]

Identifier: 189354060

GI number: 189354060

Start: 2390733

End: 2392655

Strand: Reverse

Name: fadD [H]

Synonym: BMULJ_05313

Alternate gene names: 189354060

Gene position: 2392655-2390733 (Counterclockwise)

Preceding gene: 189354061

Following gene: 189354056

Centisome position: 96.74

GC content: 70.1

Gene sequence:

>1923_bases
TTGGAAGCGGACCCGACCCAATCGCGCGGCGACGCGGCCGCGCAGACCGTTCCCGCCGGCTACCGGCCGGTCGCGATCGG
CACGGCGCCGCCGGAGATCGTGCAGCGCGACGGCTGCTGGTATCTGCGCGCGGCGACGCCGCTCGGCGCGTATCCGCGCC
GGCTCACCGACCGGCTCGTCAGCGGCGCGCAGGCGCATCCGGACCGCTGGCTCGTCGCAAGGCGCGGCGCGGACGGCGCG
TGGATCGGCATCACGTATGCGCAGATGCTCGAACGCGCGCGCGCGATCGGTCAGGCCCTGCTCGATCGCGGCCTGTCGGT
CGAGCGGCCGATCGCAATCCTGTCCGGCAACGATCTCGAGCATCTGCAGATCGCGTTCGGCGCGATGTGGGCCGGCATTC
CGTATGCGCCGCTGTCGCCCGCGTATTCGCTCGTGTCGAGCGACTACGGCAAGCTGCGTCACGCGCTCGCGCTGCTGACG
CCGGGGCTCGTGTTCGCGTCCGACGGCGACGCCTACCGCGCGGCGCTCGATGCAGCGGTGCCGGCCGACGTCGAACGCGT
GATCGTGTCGGCGCGCGACGGCATGCCGGGCGCGACGCGCTTCGCGTCGCTGCTCGATACGGTGCCGCGCGACGTCGATG
CGGCGCACGACGCGGTGACGGGCGACCGGATCGCGAAATTCCTGTTCACGTCGGGGTCGACGCGGCTGCCGAAGGCGGTG
CCGACCACGCACCGGATGCTGTGCAGCAATCAGCAGATGCTGCTCGAAACGTTTCCGCAGTTCGGCATCGAGCCGCCCGT
GCTGGTCGACTGGCTGCCGTGGAATCACACGTTCGGCGGCAGCCATAACGTCGGAATCGCGCTCTACAACGGCGGCACGC
TCTACATCGACGACGGCAAGCCGGTCGCGGGCAAGTTCGACGAAACGCTGCGCAACCTGCGCGAGATCGCGCCGACCGTC
TATTTCAACGTGCCGAAGGGCTGGGAAGAACTGACCGCCGCGCTCGAAACGGACGCCGCGCTGCGCCGCACGTTCTTTTC
GCGCGTGAAGCTCTATTTCTTCGCCGGCGCGGGGCTGTCGCAGGCCGCGTGGGATCGGCTGGAGCGCGTGACGCTCGCGC
ACTGCGGCGAGCGTATCCGGATCATGGCGGGGCTCGGGATGACCGAGGCCGCGCCGTCGTGCATGTTCACGACCGGACCG
TTCTCGGCGGCCGGTTACATCGGCCTGCCGGCACCGGGCTGCGACGCGAAGCTCGTGCCCGTCGACGGCAAGCTCGAGGC
GCGCTTTCGCGGGCCGAACGTGATGGCCGGCTACTGGCGCGCGAACGAGGCGGACGCGCGCGACGTGTTCGACGACGAGG
GCTATTACCGCAGCGGCGATGCGGTGCGCTTCGTCGATCCGCAGCGGCCCGAGATCGGGCTGATGTTCGACGGCCGCATC
GCGGAGGATTTCAAGCTGTCGTCGGGTACGTTCGTCAGCGTCGGGCCGATGCGCGCGCGCATCATTTCGAACGGCGCGCC
GTATGTGCAGGACGCGGTCGTGACGGGGATGAACCGCGACGATGTGGGCGTGATGATCTTTCCGCGCATCGACGACTGCC
GCCGTCTCGCGGGCGCCGCGCCCGATGCCGACCTGCGTGCGGTGCTGCGCGCGCCGGCCGTGCGCGCGTTCTTCGCCGAG
TTGCTCGCACGGCTGAACCGCGACGCAACCGGGAGCGCGACGCTCATCACGCGGCTGCGGATTCTCGACGAACCGCCGTC
GCTCGATCTCGGCGAAGTGACCGACAAGGGGTCGATCAATCAGCGCGCGGTGCTCGCGCATCGGGCGGCGCTGGTCGAGG
CCATGTATGCGGCCGATGCGCGCGACGATGCGGAAGCGGGACTGATCTTCGCCGACGTCGAGCGCATCGCGCGACACGGC
TGA

Upstream 100 bases:

>100_bases
CGATCGGCACGGGCTGCGCGCGTCGCAGCCGCGATCACGATACAACGACGTTCCGGCCGAGCGCAGGCGCACGCGCGCCG
GAACCGCACGGAGACAAGAC

Downstream 100 bases:

>100_bases
GGCCGCATGCGCGCCGATGCCGTTGCGCACTGCGCACTGCATGGGATGTCGCCATGCGTGCAACGCGCGGTGTCGGCGCG
CGGCGTTTGCCGCGAAACGT

Product: feruloyl-CoA synthase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MEADPTQSRGDAAAQTVPAGYRPVAIGTAPPEIVQRDGCWYLRAATPLGAYPRRLTDRLVSGAQAHPDRWLVARRGADGA
WIGITYAQMLERARAIGQALLDRGLSVERPIAILSGNDLEHLQIAFGAMWAGIPYAPLSPAYSLVSSDYGKLRHALALLT
PGLVFASDGDAYRAALDAAVPADVERVIVSARDGMPGATRFASLLDTVPRDVDAAHDAVTGDRIAKFLFTSGSTRLPKAV
PTTHRMLCSNQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIALYNGGTLYIDDGKPVAGKFDETLRNLREIAPTV
YFNVPKGWEELTAALETDAALRRTFFSRVKLYFFAGAGLSQAAWDRLERVTLAHCGERIRIMAGLGMTEAAPSCMFTTGP
FSAAGYIGLPAPGCDAKLVPVDGKLEARFRGPNVMAGYWRANEADARDVFDDEGYYRSGDAVRFVDPQRPEIGLMFDGRI
AEDFKLSSGTFVSVGPMRARIISNGAPYVQDAVVTGMNRDDVGVMIFPRIDDCRRLAGAAPDADLRAVLRAPAVRAFFAE
LLARLNRDATGSATLITRLRILDEPPSLDLGEVTDKGSINQRAVLAHRAALVEAMYAADARDDAEAGLIFADVERIARHG

Sequences:

>Translated_640_residues
MEADPTQSRGDAAAQTVPAGYRPVAIGTAPPEIVQRDGCWYLRAATPLGAYPRRLTDRLVSGAQAHPDRWLVARRGADGA
WIGITYAQMLERARAIGQALLDRGLSVERPIAILSGNDLEHLQIAFGAMWAGIPYAPLSPAYSLVSSDYGKLRHALALLT
PGLVFASDGDAYRAALDAAVPADVERVIVSARDGMPGATRFASLLDTVPRDVDAAHDAVTGDRIAKFLFTSGSTRLPKAV
PTTHRMLCSNQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIALYNGGTLYIDDGKPVAGKFDETLRNLREIAPTV
YFNVPKGWEELTAALETDAALRRTFFSRVKLYFFAGAGLSQAAWDRLERVTLAHCGERIRIMAGLGMTEAAPSCMFTTGP
FSAAGYIGLPAPGCDAKLVPVDGKLEARFRGPNVMAGYWRANEADARDVFDDEGYYRSGDAVRFVDPQRPEIGLMFDGRI
AEDFKLSSGTFVSVGPMRARIISNGAPYVQDAVVTGMNRDDVGVMIFPRIDDCRRLAGAAPDADLRAVLRAPAVRAFFAE
LLARLNRDATGSATLITRLRILDEPPSLDLGEVTDKGSINQRAVLAHRAALVEAMYAADARDDAEAGLIFADVERIARHG
>Mature_640_residues
MEADPTQSRGDAAAQTVPAGYRPVAIGTAPPEIVQRDGCWYLRAATPLGAYPRRLTDRLVSGAQAHPDRWLVARRGADGA
WIGITYAQMLERARAIGQALLDRGLSVERPIAILSGNDLEHLQIAFGAMWAGIPYAPLSPAYSLVSSDYGKLRHALALLT
PGLVFASDGDAYRAALDAAVPADVERVIVSARDGMPGATRFASLLDTVPRDVDAAHDAVTGDRIAKFLFTSGSTRLPKAV
PTTHRMLCSNQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIALYNGGTLYIDDGKPVAGKFDETLRNLREIAPTV
YFNVPKGWEELTAALETDAALRRTFFSRVKLYFFAGAGLSQAAWDRLERVTLAHCGERIRIMAGLGMTEAAPSCMFTTGP
FSAAGYIGLPAPGCDAKLVPVDGKLEARFRGPNVMAGYWRANEADARDVFDDEGYYRSGDAVRFVDPQRPEIGLMFDGRI
AEDFKLSSGTFVSVGPMRARIISNGAPYVQDAVVTGMNRDDVGVMIFPRIDDCRRLAGAAPDADLRAVLRAPAVRAFFAE
LLARLNRDATGSATLITRLRILDEPPSLDLGEVTDKGSINQRAVLAHRAALVEAMYAADARDDAEAGLIFADVERIARHG

Specific function: Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids [H]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Membrane; Peripheral membrane protein (Potential). Note=Partially membrane-associated (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1788107, Length=444, Percent_Identity=24.0990990990991, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17564090, Length=440, Percent_Identity=24.5454545454545, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17556552, Length=337, Percent_Identity=26.1127596439169, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 69212; Mature: 69212

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEADPTQSRGDAAAQTVPAGYRPVAIGTAPPEIVQRDGCWYLRAATPLGAYPRRLTDRLV
CCCCCCCCCCCHHHHCCCCCCCEEEECCCCHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
SGAQAHPDRWLVARRGADGAWIGITYAQMLERARAIGQALLDRGLSVERPIAILSGNDLE
CCCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCH
HLQIAFGAMWAGIPYAPLSPAYSLVSSDYGKLRHALALLTPGLVFASDGDAYRAALDAAV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCC
PADVERVIVSARDGMPGATRFASLLDTVPRDVDAAHDAVTGDRIAKFLFTSGSTRLPKAV
CCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PTTHRMLCSNQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIALYNGGTLYIDDGK
CHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEEECCEEEEECCC
PVAGKFDETLRNLREIAPTVYFNVPKGWEELTAALETDAALRRTFFSRVKLYFFAGAGLS
CCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
QAAWDRLERVTLAHCGERIRIMAGLGMTEAAPSCMFTTGPFSAAGYIGLPAPGCDAKLVP
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCCCEECCCCCCCCCEEEE
VDGKLEARFRGPNVMAGYWRANEADARDVFDDEGYYRSGDAVRFVDPQRPEIGLMFDGRI
CCCCEEEEECCCCEEEEEEECCCCCCHHCCCCCCCEECCCEEEEECCCCCCEEEEECCCC
AEDFKLSSGTFVSVGPMRARIISNGAPYVQDAVVTGMNRDDVGVMIFPRIDDCRRLAGAA
CCCEECCCCCEEEECCCEEEEECCCCCHHHHHHHCCCCCCCCCEEEECCCHHHHHHHCCC
PDADLRAVLRAPAVRAFFAELLARLNRDATGSATLITRLRILDEPPSLDLGEVTDKGSIN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QRAVLAHRAALVEAMYAADARDDAEAGLIFADVERIARHG
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHCC
>Mature Secondary Structure
MEADPTQSRGDAAAQTVPAGYRPVAIGTAPPEIVQRDGCWYLRAATPLGAYPRRLTDRLV
CCCCCCCCCCCHHHHCCCCCCCEEEECCCCHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
SGAQAHPDRWLVARRGADGAWIGITYAQMLERARAIGQALLDRGLSVERPIAILSGNDLE
CCCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCH
HLQIAFGAMWAGIPYAPLSPAYSLVSSDYGKLRHALALLTPGLVFASDGDAYRAALDAAV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCC
PADVERVIVSARDGMPGATRFASLLDTVPRDVDAAHDAVTGDRIAKFLFTSGSTRLPKAV
CCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PTTHRMLCSNQQMLLETFPQFGIEPPVLVDWLPWNHTFGGSHNVGIALYNGGTLYIDDGK
CHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEEECCEEEEECCC
PVAGKFDETLRNLREIAPTVYFNVPKGWEELTAALETDAALRRTFFSRVKLYFFAGAGLS
CCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
QAAWDRLERVTLAHCGERIRIMAGLGMTEAAPSCMFTTGPFSAAGYIGLPAPGCDAKLVP
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCCCEECCCCCCCCCEEEE
VDGKLEARFRGPNVMAGYWRANEADARDVFDDEGYYRSGDAVRFVDPQRPEIGLMFDGRI
CCCCEEEEECCCCEEEEEEECCCCCCHHCCCCCCCEECCCEEEEECCCCCCEEEEECCCC
AEDFKLSSGTFVSVGPMRARIISNGAPYVQDAVVTGMNRDDVGVMIFPRIDDCRRLAGAA
CCCEECCCCCEEEECCCEEEEECCCCCHHHHHHHCCCCCCCCCEEEECCCHHHHHHHCCC
PDADLRAVLRAPAVRAFFAELLARLNRDATGSATLITRLRILDEPPSLDLGEVTDKGSIN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QRAVLAHRAALVEAMYAADARDDAEAGLIFADVERIARHG
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]