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The map label for this gene is mhpT [H]

Identifier: 189354055

GI number: 189354055

Start: 2385340

End: 2386545

Strand: Reverse

Name: mhpT [H]

Synonym: BMULJ_05308

Alternate gene names: 189354055

Gene position: 2386545-2385340 (Counterclockwise)

Preceding gene: 189354056

Following gene: 189354054

Centisome position: 96.5

GC content: 71.14

Gene sequence:

>1206_bases
ATGGACACTTCCGTTGCCGAGAGGCCGGCCGTCGCGACGACGCTCGGTCTGTGTTTCGCGATCGCGCTGCTCGAGGGGCT
CGACCTGCAGTCGGTCGGCGTCGCCGCGCCGCGCATGGCGCATGAATTCGGGCTGACCGTTTCGCAGATGGGCATTGCAT
TCAGCGCGGGCACGTTCGGGCTGCTGCCGGGCGCGATGCTCGGCGGCTGGCTCGCGGACCGGATCGGCCGCAAACAGGTG
TTGATCGCGTCGGTATGCCTGTTCGGGCTGCTGTCGATCGCGACCGCGCAGGTATCGAGCTTCGCGATGCTCGTCGTCGT
GCGTGCGCTGACGGGGCTCGGCCTCGGCGGCGCGATGCCGAACCTGATCGCGCTGTCGTCCGAGGCGGTCGGCGCGCGCT
CGCGCAGCAGCGCGGTCGCCGTCATGTACTGCGGGATTCCGTTCGGCGGCGTGATCGCGTCGCTGATCGGCGTGCTGCTC
GCGGGCGACACCGAGTGGCGTCACATCTTCTACGTCGGCGGCGTCGGGCCGCTGCTGCTCGCGCCGCTGTTGATCGCGCT
GCTACCCGAGTCGCGCGCGTTTCTCGACGTCAGCGCGTCGGGCGCCGCGCGCGCGGGCGTGCGCGACACGCTGTTCGGCG
GCGGCCGCACCGGCTCGACGCTCGCATTGTGGATCAGCTACTTCTGCACGCTGATCGTGCTGTATTTCCTGCTGAACTGG
CTGCCGTCGCTGATGGCCGCGAAAGGGCTCGCGCGCGGGCAGGCCGGCATCGTGCAGATCTTCTTCAACATCGGCAGCGG
CCTCGGCGTGCTCGGCATCGGCATGTCGATGGACCGGATGCGGCCCGCGCGCGTCGTCGGCGGCATGTATGCGGGGATCG
TGCTGTCGCTTGCCGCGCTCGCGATCGCGCCGGGGCTCATGTGGCTGTCCGTCGCCGCGTTCGCGGCCGGGATGTTCGTC
GTCGGCGGCCAGTCGGTGCTGTATGCGCTCGCCGCGATCTACTACCCGACCGCGATGCGCGGCACCGGCGTGGGCTCCGC
GGTGGCCGTAGGGCGGCTCGGCTCGGTCGTCGGGCCGCTCGCCGCCGCCGAACTGCTCGCGATGGGCCGCAGCGCGTCGG
TCGTGATCGGCGCGAGCATCCCCGTCACGCTCGTCGCTGCGATCGCCGCGCTGCTGCTGATCCGCCGGCCGCACGCGCAC
GACTGA

Upstream 100 bases:

>100_bases
TAGAATCAGGCAGCCTGATAAAGCCGATCATGATCCGGTTACGACAAAGCCCTCGCGCAGGTGCGGTCGCATCGCGTGCG
GGTCCAGGTTTGGAGACGAC

Downstream 100 bases:

>100_bases
GTTCCTTCTTTCAACCCGACGCGCCGTCAGAGCGCGACATCGACGCAGGTCTGGAGACACTCATCATGAAGCACACCAAA
GCCTTGCTGGCGGCCGGCGC

Product: putative 3-hydroxyphenylpropionic transporter MhpT

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MDTSVAERPAVATTLGLCFAIALLEGLDLQSVGVAAPRMAHEFGLTVSQMGIAFSAGTFGLLPGAMLGGWLADRIGRKQV
LIASVCLFGLLSIATAQVSSFAMLVVVRALTGLGLGGAMPNLIALSSEAVGARSRSSAVAVMYCGIPFGGVIASLIGVLL
AGDTEWRHIFYVGGVGPLLLAPLLIALLPESRAFLDVSASGAARAGVRDTLFGGGRTGSTLALWISYFCTLIVLYFLLNW
LPSLMAAKGLARGQAGIVQIFFNIGSGLGVLGIGMSMDRMRPARVVGGMYAGIVLSLAALAIAPGLMWLSVAAFAAGMFV
VGGQSVLYALAAIYYPTAMRGTGVGSAVAVGRLGSVVGPLAAAELLAMGRSASVVIGASIPVTLVAAIAALLLIRRPHAH
D

Sequences:

>Translated_401_residues
MDTSVAERPAVATTLGLCFAIALLEGLDLQSVGVAAPRMAHEFGLTVSQMGIAFSAGTFGLLPGAMLGGWLADRIGRKQV
LIASVCLFGLLSIATAQVSSFAMLVVVRALTGLGLGGAMPNLIALSSEAVGARSRSSAVAVMYCGIPFGGVIASLIGVLL
AGDTEWRHIFYVGGVGPLLLAPLLIALLPESRAFLDVSASGAARAGVRDTLFGGGRTGSTLALWISYFCTLIVLYFLLNW
LPSLMAAKGLARGQAGIVQIFFNIGSGLGVLGIGMSMDRMRPARVVGGMYAGIVLSLAALAIAPGLMWLSVAAFAAGMFV
VGGQSVLYALAAIYYPTAMRGTGVGSAVAVGRLGSVVGPLAAAELLAMGRSASVVIGASIPVTLVAAIAALLLIRRPHAH
D
>Mature_401_residues
MDTSVAERPAVATTLGLCFAIALLEGLDLQSVGVAAPRMAHEFGLTVSQMGIAFSAGTFGLLPGAMLGGWLADRIGRKQV
LIASVCLFGLLSIATAQVSSFAMLVVVRALTGLGLGGAMPNLIALSSEAVGARSRSSAVAVMYCGIPFGGVIASLIGVLL
AGDTEWRHIFYVGGVGPLLLAPLLIALLPESRAFLDVSASGAARAGVRDTLFGGGRTGSTLALWISYFCTLIVLYFLLNW
LPSLMAAKGLARGQAGIVQIFFNIGSGLGVLGIGMSMDRMRPARVVGGMYAGIVLSLAALAIAPGLMWLSVAAFAAGMFV
VGGQSVLYALAAIYYPTAMRGTGVGSAVAVGRLGSVVGPLAAAELLAMGRSASVVIGASIPVTLVAAIAALLLIRRPHAH
D

Specific function: Could be a transporter for 3-phenylpropionate (hydrocinnamic acid) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=418, Percent_Identity=22.7272727272727, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI166064021, Length=395, Percent_Identity=24.8101265822785, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI154350196, Length=226, Percent_Identity=27.4336283185841, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081723, Length=383, Percent_Identity=48.5639686684073, Blast_Score=307, Evalue=9e-85,
Organism=Escherichia coli, GI1786229, Length=389, Percent_Identity=26.2210796915167, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789152, Length=263, Percent_Identity=24.7148288973384, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082231, Length=192, Percent_Identity=25, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40744; Mature: 40744

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSVAERPAVATTLGLCFAIALLEGLDLQSVGVAAPRMAHEFGLTVSQMGIAFSAGTFG
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHCCEECCCCHH
LLPGAMLGGWLADRIGRKQVLIASVCLFGLLSIATAQVSSFAMLVVVRALTGLGLGGAMP
HCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NLIALSSEAVGARSRSSAVAVMYCGIPFGGVIASLIGVLLAGDTEWRHIFYVGGVGPLLL
HHHEECCHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHH
APLLIALLPESRAFLDVSASGAARAGVRDTLFGGGRTGSTLALWISYFCTLIVLYFLLNW
HHHHHHHCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LPSLMAAKGLARGQAGIVQIFFNIGSGLGVLGIGMSMDRMRPARVVGGMYAGIVLSLAAL
HHHHHHHHHHCCCCHHHHHHEEHHCCCCCCEECCCCHHHCCHHHHHHHHHHHHHHHHHHH
AIAPGLMWLSVAAFAAGMFVVGGQSVLYALAAIYYPTAMRGTGVGSAVAVGRLGSVVGPL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AAAELLAMGRSASVVIGASIPVTLVAAIAALLLIRRPHAHD
HHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDTSVAERPAVATTLGLCFAIALLEGLDLQSVGVAAPRMAHEFGLTVSQMGIAFSAGTFG
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHCCEECCCCHH
LLPGAMLGGWLADRIGRKQVLIASVCLFGLLSIATAQVSSFAMLVVVRALTGLGLGGAMP
HCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NLIALSSEAVGARSRSSAVAVMYCGIPFGGVIASLIGVLLAGDTEWRHIFYVGGVGPLLL
HHHEECCHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHH
APLLIALLPESRAFLDVSASGAARAGVRDTLFGGGRTGSTLALWISYFCTLIVLYFLLNW
HHHHHHHCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LPSLMAAKGLARGQAGIVQIFFNIGSGLGVLGIGMSMDRMRPARVVGGMYAGIVLSLAAL
HHHHHHHHHHCCCCHHHHHHEEHHCCCCCCEECCCCHHHCCHHHHHHHHHHHHHHHHHHH
AIAPGLMWLSVAAFAAGMFVVGGQSVLYALAAIYYPTAMRGTGVGSAVAVGRLGSVVGPL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AAAELLAMGRSASVVIGASIPVTLVAAIAALLLIRRPHAHD
HHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]