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The map label for this gene is catB [H]

Identifier: 189354037

GI number: 189354037

Start: 2364878

End: 2366014

Strand: Reverse

Name: catB [H]

Synonym: BMULJ_05290

Alternate gene names: 189354037

Gene position: 2366014-2364878 (Counterclockwise)

Preceding gene: 189354038

Following gene: 189354036

Centisome position: 95.67

GC content: 68.43

Gene sequence:

>1137_bases
ATGACCCCGATCACCATCGAACGCATCGAAACCCGGCTCGTCGATCTGCCGACGATCCGTCCGCACAAGCTGTCGGTCGC
GACCATGCACGGCCAGACGCTGATGCTGGTGAAGGTGTTCTGCAGCGACGGCGTAACGGGCATCGGCGAAGGCACGACGA
TCGCGGGGATGGCCTACGGCCCGGAAAGCCCCGAAGCGATGAAGCTCGCGATCGATACGTACTTCGCGCCGGCGATGATC
GGCCGCGATGCGACGCGCATCCAGGCGCTGATGGCGCATGTCGGCAAGCTCGTGAAGGTCAACCATTTCGCGAAAAGCGC
GCTCGAAATGGCGCTGCTCGACGCGCACGGCAAGCGTCTCGGCGTGCCGGTGAGCGAGCTGCTCGGCGGACGCCGCCGCG
AGCGCCTGCCGGTCGCATGGACGCTGGCATCCGGCGACACCGCGCGCGACATCGACGAGGCCGAGCACATGCTCGACGTG
CGCCGGCACAACGTGTTCAAGCTGAAGATCGGCGCGAAGGCGCTCGATGCCGACATCCGCCACGTCGCCGCGATCAAGAA
GGCGCTCGGCGATCGCGCGGCGGTGCGCGTCGACGTGAACATGGCGTGGAGCGAGACGCAGGCCGCACGCGCGCTGCCCG
CGCTCGCGGACGCCGGCTGCGAACTGGTCGAGCAGCCGGTCGCATCGGCCGCCGCGCTCGCACGGCTGATGCGCCGCTTC
CCCGTCGCGCTGATGGCCGACGAAATCCTGCAGGGCCCGGACAGCGCGTTCGACATCGCGAAGCAGCACGGCGCGGATGT
CTTCGCGATCAAGATCGAACAGAGCGGCGGGCTGTTCGCCGCGCAGCGCGTCGCGACGATCGCCGATGCGGCCGGCATCG
AGCTGTACGGCGGCACGATGCTCGAAGGCGCGGTGAGCACGGTCGCGTCCGCGCATCTGTTCGCGAGCTTCGCGAACCTG
CAGTGGGGCACCGAGCTGTTCGGGCCGCTGCTGATCACCGAAGAGATTCTCGCGACGCCGCTCGACTACAGCGACTTCGA
GCTGACCGTGCCGAGCGGCCCGGGCCTCGGCATCGAGCTCGACGACGAGAAGGTTGCGCGCTTTACGCGCGACGGGCTGA
CGAAGGTCGTCCGCTAA

Upstream 100 bases:

>100_bases
TACCTGACAGGTATGGATAGGGGTGCCCAAAAGTATTGGACGCTGCATTTGGGCGAGACGTATAAATCGGTCCAAGCACT
CCACATACACGACGTATCCC

Downstream 100 bases:

>100_bases
CTGAATTCCCCACACACGTATCAGGATCATCACGATGCTTTTCCACGTACGCATGGACGTCAATCTGCCGGCCGACATGC
CGGCCGGCGTGGCCGACGAG

Product: muconate cycloisomerase

Products: NA

Alternate protein names: Cis,cis-muconate lactonizing enzyme I 1; MLE 1; Muconate cycloisomerase I 1 [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTPITIERIETRLVDLPTIRPHKLSVATMHGQTLMLVKVFCSDGVTGIGEGTTIAGMAYGPESPEAMKLAIDTYFAPAMI
GRDATRIQALMAHVGKLVKVNHFAKSALEMALLDAHGKRLGVPVSELLGGRRRERLPVAWTLASGDTARDIDEAEHMLDV
RRHNVFKLKIGAKALDADIRHVAAIKKALGDRAAVRVDVNMAWSETQAARALPALADAGCELVEQPVASAAALARLMRRF
PVALMADEILQGPDSAFDIAKQHGADVFAIKIEQSGGLFAAQRVATIADAAGIELYGGTMLEGAVSTVASAHLFASFANL
QWGTELFGPLLITEEILATPLDYSDFELTVPSGPGLGIELDDEKVARFTRDGLTKVVR

Sequences:

>Translated_378_residues
MTPITIERIETRLVDLPTIRPHKLSVATMHGQTLMLVKVFCSDGVTGIGEGTTIAGMAYGPESPEAMKLAIDTYFAPAMI
GRDATRIQALMAHVGKLVKVNHFAKSALEMALLDAHGKRLGVPVSELLGGRRRERLPVAWTLASGDTARDIDEAEHMLDV
RRHNVFKLKIGAKALDADIRHVAAIKKALGDRAAVRVDVNMAWSETQAARALPALADAGCELVEQPVASAAALARLMRRF
PVALMADEILQGPDSAFDIAKQHGADVFAIKIEQSGGLFAAQRVATIADAAGIELYGGTMLEGAVSTVASAHLFASFANL
QWGTELFGPLLITEEILATPLDYSDFELTVPSGPGLGIELDDEKVARFTRDGLTKVVR
>Mature_377_residues
TPITIERIETRLVDLPTIRPHKLSVATMHGQTLMLVKVFCSDGVTGIGEGTTIAGMAYGPESPEAMKLAIDTYFAPAMIG
RDATRIQALMAHVGKLVKVNHFAKSALEMALLDAHGKRLGVPVSELLGGRRRERLPVAWTLASGDTARDIDEAEHMLDVR
RHNVFKLKIGAKALDADIRHVAAIKKALGDRAAVRVDVNMAWSETQAARALPALADAGCELVEQPVASAAALARLMRRFP
VALMADEILQGPDSAFDIAKQHGADVFAIKIEQSGGLFAAQRVATIADAAGIELYGGTMLEGAVSTVASAHLFASFANLQ
WGTELFGPLLITEEILATPLDYSDFELTVPSGPGLGIELDDEKVARFTRDGLTKVVR

Specific function: Catalyzes a syn cycloisomerization [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=361, Percent_Identity=25.207756232687, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013370
- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.5.1.1 [H]

Molecular weight: Translated: 40477; Mature: 40346

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00908 MR_MLE_1 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPITIERIETRLVDLPTIRPHKLSVATMHGQTLMLVKVFCSDGVTGIGEGTTIAGMAYG
CCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEHHHHHCCCCCCCCCCCEEEEEECC
PESPEAMKLAIDTYFAPAMIGRDATRIQALMAHVGKLVKVNHFAKSALEMALLDAHGKRL
CCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVPVSELLGGRRRERLPVAWTLASGDTARDIDEAEHMLDVRRHNVFKLKIGAKALDADIR
CCCHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHH
HVAAIKKALGDRAAVRVDVNMAWSETQAARALPALADAGCELVEQPVASAAALARLMRRF
HHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
PVALMADEILQGPDSAFDIAKQHGADVFAIKIEQSGGLFAAQRVATIADAAGIELYGGTM
CHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEECCHH
LEGAVSTVASAHLFASFANLQWGTELFGPLLITEEILATPLDYSDFELTVPSGPGLGIEL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEE
DDEKVARFTRDGLTKVVR
CHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPITIERIETRLVDLPTIRPHKLSVATMHGQTLMLVKVFCSDGVTGIGEGTTIAGMAYG
CCCCHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEHHHHHCCCCCCCCCCCEEEEEECC
PESPEAMKLAIDTYFAPAMIGRDATRIQALMAHVGKLVKVNHFAKSALEMALLDAHGKRL
CCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVPVSELLGGRRRERLPVAWTLASGDTARDIDEAEHMLDVRRHNVFKLKIGAKALDADIR
CCCHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHH
HVAAIKKALGDRAAVRVDVNMAWSETQAARALPALADAGCELVEQPVASAAALARLMRRF
HHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
PVALMADEILQGPDSAFDIAKQHGADVFAIKIEQSGGLFAAQRVATIADAAGIELYGGTM
CHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEECCHH
LEGAVSTVASAHLFASFANLQWGTELFGPLLITEEILATPLDYSDFELTVPSGPGLGIEL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEE
DDEKVARFTRDGLTKVVR
CHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9473520; 9260969 [H]