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The map label for this gene is hlyIII [C]

Identifier: 189354025

GI number: 189354025

Start: 2353473

End: 2354093

Strand: Reverse

Name: hlyIII [C]

Synonym: BMULJ_05278

Alternate gene names: 189354025

Gene position: 2354093-2353473 (Counterclockwise)

Preceding gene: 189354026

Following gene: 189354022

Centisome position: 95.19

GC content: 64.25

Gene sequence:

>621_bases
GTGCATGTCGGTGAGCGTTTCAACAGCATTACGCACCTCGTCGGCGCGCTATTGTCGGTCGCGGGGCTGGCGACGCTCGT
GACGATGGGCGCACTCGACGGCGACGCTTACAAGGTCGTCAGCTTCAGCGTGTACGGCGCGATGCTCTGCGTGCTCTATG
CGATCTCGACGCTCTATCACAGCGTGCGCGATCCGCGCCTGAAGGCGATCCTGCAGAAATGCGACCACGCGGCCATCTAT
CTGCTGATTGCGGGCAGTTATACGCCGTTTACGCTCGTCACGCTGCGCGGGCCGTGGGGCTGGTCGCTGTTCGGCGTGAG
CTGGGGGCTCGCGGTGTTCGGCATCGTGCAGGAACTGACGCTCGGCCGGCGTACGCGCGTGCTGTCGATGGTGCTGTACG
TGCTGATGGGATGGCTCGCGCTCGTCGCGGTCCGTCCGCTGATTCACGCGCTGCCGCCCGTCGGCACCGCATGGCTCGTC
GCCGGCGGCGTGATCTATAGCGTCGGCATCTACTTCTTCATCAACGACGAACGGATTCGTCACGGCCACGGGATCTGGCA
TCTGTTCGTGCTGGCCGGCAGCCTGTGCCAGTTCGTCAGTGTCGCGATGTATGTCGCGTGA

Upstream 100 bases:

>100_bases
TCACGGCGCTTTTTCATTGCGCGCGCGGCGCATCGCCGTTGTGCGGCGCCCGGTATCATGGAGCCCGTTCGTATCGAGGA
TTCGTGCAGGAGGATGGGCC

Downstream 100 bases:

>100_bases
GCGCAGCGCGTGACGCTGCGCGGCGGCGCGACTGTCATCCGCGATCGCGCGCGGCTGCGGCCGCCGTCAACGCCTGGAAG
CCGACCCATCCCCAGTACAC

Product: hemolysin III

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MHVGERFNSITHLVGALLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYHSVRDPRLKAILQKCDHAAIY
LLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAVFGIVQELTLGRRTRVLSMVLYVLMGWLALVAVRPLIHALPPVGTAWLV
AGGVIYSVGIYFFINDERIRHGHGIWHLFVLAGSLCQFVSVAMYVA

Sequences:

>Translated_206_residues
MHVGERFNSITHLVGALLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYHSVRDPRLKAILQKCDHAAIY
LLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAVFGIVQELTLGRRTRVLSMVLYVLMGWLALVAVRPLIHALPPVGTAWLV
AGGVIYSVGIYFFINDERIRHGHGIWHLFVLAGSLCQFVSVAMYVA
>Mature_206_residues
MHVGERFNSITHLVGALLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYHSVRDPRLKAILQKCDHAAIY
LLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAVFGIVQELTLGRRTRVLSMVLYVLMGWLALVAVRPLIHALPPVGTAWLV
AGGVIYSVGIYFFINDERIRHGHGIWHLFVLAGSLCQFVSVAMYVA

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=204, Percent_Identity=30.3921568627451, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI154759277, Length=228, Percent_Identity=27.6315789473684, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI52630445, Length=203, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1789266, Length=202, Percent_Identity=42.0792079207921, Blast_Score=157, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI71996356, Length=166, Percent_Identity=34.3373493975904, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640324, Length=182, Percent_Identity=32.4175824175824, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 22483; Mature: 22483

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVGERFNSITHLVGALLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVRDPRLKAILQKCDHAAIYLLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAVFGIVQELT
HHCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGRRTRVLSMVLYVLMGWLALVAVRPLIHALPPVGTAWLVAGGVIYSVGIYFFINDERIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCHHH
HGHGIWHLFVLAGSLCQFVSVAMYVA
HCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHVGERFNSITHLVGALLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVRDPRLKAILQKCDHAAIYLLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAVFGIVQELT
HHCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGRRTRVLSMVLYVLMGWLALVAVRPLIHALPPVGTAWLVAGGVIYSVGIYFFINDERIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCHHH
HGHGIWHLFVLAGSLCQFVSVAMYVA
HCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]