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The map label for this gene is ispH [H]

Identifier: 189354019

GI number: 189354019

Start: 2348650

End: 2349591

Strand: Direct

Name: ispH [H]

Synonym: BMULJ_05272

Alternate gene names: 189354019

Gene position: 2348650-2349591 (Clockwise)

Preceding gene: 189354017

Following gene: 189354020

Centisome position: 94.97

GC content: 66.45

Gene sequence:

>942_bases
ATGCGAGTCATCCTTGCCCAGCCTCGCGGCTTTTGTGCGGGGGTTGTCCGCGCCATCGAGATCGTCGATCGCGCGCTGCA
ACAGCACGGCGCGCCGGTTTATGTGCGTCATGAAATCGTCCACAACCGGCACGTCGTCGAAAATCTGCGTAATAAAGGGG
CACGATTCGTTGAGGAACTCGACGAGGTGCCGCATGGCGCCGTCGCGATCTTCAGCGCGCACGGCGTCGCCCAGACGGTC
GAGCGCGACGCGCAGACGCGCGGGCTCGACGTGCTCGACGCCACCTGCCCGCTCGTCACGAAAGTGCACGTGCAGGGCCG
GCAGTACGTCGCGGCCGGCCGCCGGCTGATCCTGATCGGCCACGCCGGGCATCCGGAAGTCGAGGGCACGATCGGCCAGA
TTCCGGCCGAGGTGATCCTCGTGCAAAGTGAAGCGGAAGTCGATACGCTGACGCTGCCGGTCGACACGCCGGTTGCGTAC
GTGACGCAGACGACGCTGTCGGTCGACGACACGCGCGGCATCATCGAAGCGCTGCAGCGCCGGTTCACCGACATCGTCGG
CCCGGACACGCGCGACATCTGCTACGCGACGCAAAACCGCCAGGCCGCCGTGCGCGAGCTGAGCGGGCAAGTCGACGTGC
TGCTCGTGGTCGGCGCGACCAACAGTTCGAATTCGAACCGGCTGCGCGAGATCGGCACCGAAAGCGGCGTGCCGAGCTAC
CTGGTCGCCGACGGCTCGGAAGTGAAGGCCGAATGGTTCGCAGGCGTGCAGACGGTCGGGCTGACCGCCGGCGCGTCGGC
ACCGGAAGAGATGGTCGAGGATGTGATCGGCGCGCTGCGCGCGCTGGGGCCCGTCGAGGTCACGACGATGGCGGGCCGTG
AAGAAAAAGTCGAATTCAAGCTGCCGGCGAAGCTCATGCAAGCTGTCGCCCGCGAAGTTTAA

Upstream 100 bases:

>100_bases
CCGGGCCGGTCGTTCCTGCCTTCATAACATCAAGCCGGGGCAATCGAGCTGAAGTGCCAACTCCTCGAACCCCGTTTCTG
TCGTCGGAGTTCGCTCACTT

Downstream 100 bases:

>100_bases
GGAGGACAACTCTTGTCTATTCCGCTGCTCCAGCAAGTCCGCGTCGGCGCGTACATCATGCGCCAACACCTGTCCGGCAA
CAAACGCTATCCGCTCGCGC

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVENLRNKGARFVEELDEVPHGAVAIFSAHGVAQTV
ERDAQTRGLDVLDATCPLVTKVHVQGRQYVAAGRRLILIGHAGHPEVEGTIGQIPAEVILVQSEAEVDTLTLPVDTPVAY
VTQTTLSVDDTRGIIEALQRRFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLLVVGATNSSNSNRLREIGTESGVPSY
LVADGSEVKAEWFAGVQTVGLTAGASAPEEMVEDVIGALRALGPVEVTTMAGREEKVEFKLPAKLMQAVAREV

Sequences:

>Translated_313_residues
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVENLRNKGARFVEELDEVPHGAVAIFSAHGVAQTV
ERDAQTRGLDVLDATCPLVTKVHVQGRQYVAAGRRLILIGHAGHPEVEGTIGQIPAEVILVQSEAEVDTLTLPVDTPVAY
VTQTTLSVDDTRGIIEALQRRFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLLVVGATNSSNSNRLREIGTESGVPSY
LVADGSEVKAEWFAGVQTVGLTAGASAPEEMVEDVIGALRALGPVEVTTMAGREEKVEFKLPAKLMQAVAREV
>Mature_313_residues
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVENLRNKGARFVEELDEVPHGAVAIFSAHGVAQTV
ERDAQTRGLDVLDATCPLVTKVHVQGRQYVAAGRRLILIGHAGHPEVEGTIGQIPAEVILVQSEAEVDTLTLPVDTPVAY
VTQTTLSVDDTRGIIEALQRRFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLLVVGATNSSNSNRLREIGTESGVPSY
LVADGSEVKAEWFAGVQTVGLTAGASAPEEMVEDVIGALRALGPVEVTTMAGREEKVEFKLPAKLMQAVAREV

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=308, Percent_Identity=53.5714285714286, Blast_Score=333, Evalue=6e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 33724; Mature: 33724

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVENLRNKGARFVEEL
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DEVPHGAVAIFSAHGVAQTVERDAQTRGLDVLDATCPLVTKVHVQGRQYVAAGRRLILIG
HHCCCCEEEEEECCCHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCHHHHCCCEEEEEE
HAGHPEVEGTIGQIPAEVILVQSEAEVDTLTLPVDTPVAYVTQTTLSVDDTRGIIEALQR
CCCCCCCCCHHHCCCEEEEEEECCCCCEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHH
RFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLLVVGATNSSNSNRLREIGTESGVPSY
HHHHHCCCCCCCEEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCE
LVADGSEVKAEWFAGVQTVGLTAGASAPEEMVEDVIGALRALGPVEVTTMAGREEKVEFK
EEECCCHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEE
LPAKLMQAVAREV
CCHHHHHHHHHCC
>Mature Secondary Structure
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVENLRNKGARFVEEL
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DEVPHGAVAIFSAHGVAQTVERDAQTRGLDVLDATCPLVTKVHVQGRQYVAAGRRLILIG
HHCCCCEEEEEECCCHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCHHHHCCCEEEEEE
HAGHPEVEGTIGQIPAEVILVQSEAEVDTLTLPVDTPVAYVTQTTLSVDDTRGIIEALQR
CCCCCCCCCHHHCCCEEEEEEECCCCCEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHH
RFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLLVVGATNSSNSNRLREIGTESGVPSY
HHHHHCCCCCCCEEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCE
LVADGSEVKAEWFAGVQTVGLTAGASAPEEMVEDVIGALRALGPVEVTTMAGREEKVEFK
EEECCCHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEE
LPAKLMQAVAREV
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA