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The map label for this gene is ycgM [C]

Identifier: 189353989

GI number: 189353989

Start: 2312495

End: 2313343

Strand: Reverse

Name: ycgM [C]

Synonym: BMULJ_05242

Alternate gene names: 189353989

Gene position: 2313343-2312495 (Counterclockwise)

Preceding gene: 189353992

Following gene: 189353987

Centisome position: 93.54

GC content: 68.2

Gene sequence:

>849_bases
ATGAAACTGCTTCGCTATGGCCCGCCCGGCCAGGAAAAGCCCGGCATTCTCGACGCGGACGGCCGCATCCGCGATCTGTC
CGCCCATGTGCCGGATCTCGCGGGCGACGTCCTGTCCGACGCGGGTCTTGCGCGACTGCGCGCGCTGGATCCCGCCACGC
TGCCGCTGGTGTCGGGCGAGCCGCGCATCGGCGCGTGCGTCGGCCGCGTCGGCAAGTTCATCGGCATTGGTCTGAACTAT
GCCGATCACGCGGCGGAAGCGGGGATGCCGGTGCCGAAGGAGCCGGTCGTGTTCGGCAAGTGGACGAGCTCGATCTGCGG
CCCGAACGACGGAATCGACATTCCGAAGGGCTCGGTGAAGACCGACTGGGAAGTGGAGCTCGGCGTCGTGATCGGCGCGC
CGTGCAAGGACGTCGACGAAGCGCGCGCGCTCGACTACGTCGCCGGTTATTGCGTGGTCAACGACGTGTCGGAGCGCGAA
TGGCAGATCGAGCGCGGCGGCCAGTGGGACAAGGGCAAGGGCTTCGACACGTTCGGCCCGATCGGCCCCTGGCTCGTCAC
GCGCGACGAGGTGCCGGACCCGCAGTCGCTCGACCTGTGGCTCGAAGTGGACGGCCACCGCTATCAGAACGGCAACACGC
GCACGATGGTGTTCACCGTCGCGCAGCTGATCGCGTATCTGTCGAGCTGCATGACGCTGCAGCCCGGCGACGTGATCACG
ACCGGCACGCCGCCCGGCGTCGGGATGGGCATCAAGCCGGCGCCCGTCTATCTGAAGGCCGGCCAGATGGTGCGGCTCGG
CATAGAAGGACTCGGCGAGCAATTGCAGCTCACGCGCGCCGCGCGCTGA

Upstream 100 bases:

>100_bases
CCGCGCATGCCATCGACGATCGACGATCAATCCGGCGAGCCGCTGCGCGCTGCGGTGGCGGCCGGTATCCTGACACATTC
GACTACAGAGGTTGAGCACG

Downstream 100 bases:

>100_bases
GCGGCACCGGCGGCAGACGGCGCGGGCCCGATCGGGCTGCGCGCGAAGAGCCGAAAGCACACAGCCCGATACCGGATCGC
CCGGTATCGGGCTGTCGTCG

Product: putative fumarylacetoacetate hydrolase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKLLRYGPPGQEKPGILDADGRIRDLSAHVPDLAGDVLSDAGLARLRALDPATLPLVSGEPRIGACVGRVGKFIGIGLNY
ADHAAEAGMPVPKEPVVFGKWTSSICGPNDGIDIPKGSVKTDWEVELGVVIGAPCKDVDEARALDYVAGYCVVNDVSERE
WQIERGGQWDKGKGFDTFGPIGPWLVTRDEVPDPQSLDLWLEVDGHRYQNGNTRTMVFTVAQLIAYLSSCMTLQPGDVIT
TGTPPGVGMGIKPAPVYLKAGQMVRLGIEGLGEQLQLTRAAR

Sequences:

>Translated_282_residues
MKLLRYGPPGQEKPGILDADGRIRDLSAHVPDLAGDVLSDAGLARLRALDPATLPLVSGEPRIGACVGRVGKFIGIGLNY
ADHAAEAGMPVPKEPVVFGKWTSSICGPNDGIDIPKGSVKTDWEVELGVVIGAPCKDVDEARALDYVAGYCVVNDVSERE
WQIERGGQWDKGKGFDTFGPIGPWLVTRDEVPDPQSLDLWLEVDGHRYQNGNTRTMVFTVAQLIAYLSSCMTLQPGDVIT
TGTPPGVGMGIKPAPVYLKAGQMVRLGIEGLGEQLQLTRAAR
>Mature_282_residues
MKLLRYGPPGQEKPGILDADGRIRDLSAHVPDLAGDVLSDAGLARLRALDPATLPLVSGEPRIGACVGRVGKFIGIGLNY
ADHAAEAGMPVPKEPVVFGKWTSSICGPNDGIDIPKGSVKTDWEVELGVVIGAPCKDVDEARALDYVAGYCVVNDVSERE
WQIERGGQWDKGKGFDTFGPIGPWLVTRDEVPDPQSLDLWLEVDGHRYQNGNTRTMVFTVAQLIAYLSSCMTLQPGDVIT
TGTPPGVGMGIKPAPVYLKAGQMVRLGIEGLGEQLQLTRAAR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=282, Percent_Identity=43.9716312056738, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI40786394, Length=282, Percent_Identity=42.9078014184397, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI66348062, Length=210, Percent_Identity=38.0952380952381, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI215422413, Length=203, Percent_Identity=38.423645320197, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=38.6138613861386, Blast_Score=135, Evalue=3e-32,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=39.010989010989, Blast_Score=128, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=37.4301675977654, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6324161, Length=213, Percent_Identity=32.3943661971831, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI28572127, Length=204, Percent_Identity=48.0392156862745, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI28571789, Length=205, Percent_Identity=41.9512195121951, Blast_Score=151, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24663695, Length=203, Percent_Identity=38.423645320197, Blast_Score=147, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30170; Mature: 30170

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRYGPPGQEKPGILDADGRIRDLSAHVPDLAGDVLSDAGLARLRALDPATLPLVSGE
CCCCCCCCCCCCCCCEECCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCC
PRIGACVGRVGKFIGIGLNYADHAAEAGMPVPKEPVVFGKWTSSICGPNDGIDIPKGSVK
CCHHHHHHHHHHHEECCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
TDWEVELGVVIGAPCKDVDEARALDYVAGYCVVNDVSEREWQIERGGQWDKGKGFDTFGP
CCCEEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCEEECCCCCCCCCCCCCCCCCC
IGPWLVTRDEVPDPQSLDLWLEVDGHRYQNGNTRTMVFTVAQLIAYLSSCMTLQPGDVIT
CCCEEEECCCCCCCCCEEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHCEECCCCEEE
TGTPPGVGMGIKPAPVYLKAGQMVRLGIEGLGEQLQLTRAAR
CCCCCCCCCCCCCCCEEEECCCEEEECHHCCCHHHHHHHCCC
>Mature Secondary Structure
MKLLRYGPPGQEKPGILDADGRIRDLSAHVPDLAGDVLSDAGLARLRALDPATLPLVSGE
CCCCCCCCCCCCCCCEECCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCC
PRIGACVGRVGKFIGIGLNYADHAAEAGMPVPKEPVVFGKWTSSICGPNDGIDIPKGSVK
CCHHHHHHHHHHHEECCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
TDWEVELGVVIGAPCKDVDEARALDYVAGYCVVNDVSEREWQIERGGQWDKGKGFDTFGP
CCCEEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCEEECCCCCCCCCCCCCCCCCC
IGPWLVTRDEVPDPQSLDLWLEVDGHRYQNGNTRTMVFTVAQLIAYLSSCMTLQPGDVIT
CCCEEEECCCCCCCCCEEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHCEECCCCEEE
TGTPPGVGMGIKPAPVYLKAGQMVRLGIEGLGEQLQLTRAAR
CCCCCCCCCCCCCCCEEEECCCEEEECHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA