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The map label for this gene is gloB [H]

Identifier: 189353959

GI number: 189353959

Start: 2275204

End: 2276274

Strand: Reverse

Name: gloB [H]

Synonym: BMULJ_05212

Alternate gene names: 189353959

Gene position: 2276274-2275204 (Counterclockwise)

Preceding gene: 189353962

Following gene: 189353958

Centisome position: 92.04

GC content: 71.24

Gene sequence:

>1071_bases
ATGATCTTCCGGCAACTGTTCGACCCGCAATCGTCTACCTACACGTACCTGCTCGCCGATCCGGCCGCGCGCGAAGCGTT
GCTGATCGACCCCGTCTTCGAGCAGGTGCGCCGCGACGCCGCGCTGCTCGACGAGCTTGGGCTGCGGCTCGTCGCGACGA
TCGACACGCACGTGCATGCGGATCACGTGACGGGCGCGTGGCTGCTGAAGCAGCACACCGGCAGCGCGATCGCGATTTCG
GCCGACAGCGGCGCGCAGGGCGCCGACCGCTATCTGCGCGACGGCGATCGCTGCACGTTCGGCGCGCGCTACGTGACAGT
GCGCGCGACGCCCGGCCACACGAGCGGCTGCATCAGCCTCGTGCTCGACGACGAATCGAAGGCATTCACCGGCGACTGTC
TGCTGATTCGCGGCACGGGCCGCACCGATTTCCAGCAGGGCGACCCGCGCGCGCTGTACCGCTCGGTGCACGGCCGGCTG
TTCACGCTGCCGGCCGCGTGCCTGCTGTATCCGGCGCACGACTACCGCGGGCTGTCGGTGACGAGCGTCGCCGAGGAGCG
ACGCTTCAATCCGCGGCTCGGCGGCGATCTGAGCGAGGACGACTTCGCCGGTTACATGCGCAACCTCGGGCTCGCGCACC
CGCGGCAGATCGACGTCGCGGTGCCCGCGAATCTGCGCTGCGGCGTCGCGGCGAGCGCGCCCGATGCACGCGACGCGGCC
GACTGGGCGCCGCTCGCGTACACGTTCGCCGGATTCTGGGAAATCGATGCGCAGTGGCTCGAGGATCATCTGACGGCGGT
GCAGATCGTCGACGTGCGCGAGCCCGACGAATTCACGGGCCCGCTCGGCCATCTGCCGGGCGCGACGCCGATCCCGCTCG
GCGAGCTGGCCGCGCGCGCCGGCGAACTCGCGCGCGAGCGGCCGATCGTCACCGTATGCCGCGCGGGCGGACGTTCCGCG
CAGGCGACCGTGCTGCTGCGCAACGCGGGCTTCGACCGCGTCGCGAATCTCGGCGGCGGCATGCTGCGCTGGCGTGCCGA
AGGGCGCATCGTGACGGACGGCCGCGCATAG

Upstream 100 bases:

>100_bases
CGATCGACGGTCGCGCCGTGCGCGACGTGCACCGCCACCGCGGCGGCGCGCGCGTTTTGACCTACGCTAGAGAGACGCGC
CACGCGACGGAGCCATTCCG

Downstream 100 bases:

>100_bases
GCGCGGCGCAGCGCGGTTTTCGGCGATGAGGGTGCCGATGTCGAATCGGCGGCTCGCCGATCGTCGTCACGGTATCGACC
CTGCCGCGCCGCACGACGCG

Product: hydroxyacylglutathione hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MIFRQLFDPQSSTYTYLLADPAAREALLIDPVFEQVRRDAALLDELGLRLVATIDTHVHADHVTGAWLLKQHTGSAIAIS
ADSGAQGADRYLRDGDRCTFGARYVTVRATPGHTSGCISLVLDDESKAFTGDCLLIRGTGRTDFQQGDPRALYRSVHGRL
FTLPAACLLYPAHDYRGLSVTSVAEERRFNPRLGGDLSEDDFAGYMRNLGLAHPRQIDVAVPANLRCGVAASAPDARDAA
DWAPLAYTFAGFWEIDAQWLEDHLTAVQIVDVREPDEFTGPLGHLPGATPIPLGELAARAGELARERPIVTVCRAGGRSA
QATVLLRNAGFDRVANLGGGMLRWRAEGRIVTDGRA

Sequences:

>Translated_356_residues
MIFRQLFDPQSSTYTYLLADPAAREALLIDPVFEQVRRDAALLDELGLRLVATIDTHVHADHVTGAWLLKQHTGSAIAIS
ADSGAQGADRYLRDGDRCTFGARYVTVRATPGHTSGCISLVLDDESKAFTGDCLLIRGTGRTDFQQGDPRALYRSVHGRL
FTLPAACLLYPAHDYRGLSVTSVAEERRFNPRLGGDLSEDDFAGYMRNLGLAHPRQIDVAVPANLRCGVAASAPDARDAA
DWAPLAYTFAGFWEIDAQWLEDHLTAVQIVDVREPDEFTGPLGHLPGATPIPLGELAARAGELARERPIVTVCRAGGRSA
QATVLLRNAGFDRVANLGGGMLRWRAEGRIVTDGRA
>Mature_356_residues
MIFRQLFDPQSSTYTYLLADPAAREALLIDPVFEQVRRDAALLDELGLRLVATIDTHVHADHVTGAWLLKQHTGSAIAIS
ADSGAQGADRYLRDGDRCTFGARYVTVRATPGHTSGCISLVLDDESKAFTGDCLLIRGTGRTDFQQGDPRALYRSVHGRL
FTLPAACLLYPAHDYRGLSVTSVAEERRFNPRLGGDLSEDDFAGYMRNLGLAHPRQIDVAVPANLRCGVAASAPDARDAA
DWAPLAYTFAGFWEIDAQWLEDHLTAVQIVDVREPDEFTGPLGHLPGATPIPLGELAARAGELARERPIVTVCRAGGRSA
QATVLLRNAGFDRVANLGGGMLRWRAEGRIVTDGRA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=230, Percent_Identity=56.9565217391304, Blast_Score=261, Evalue=5e-70,
Organism=Homo sapiens, GI21703352, Length=171, Percent_Identity=32.1637426900585, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI116642887, Length=171, Percent_Identity=32.1637426900585, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1787158, Length=197, Percent_Identity=28.9340101522843, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538952, Length=227, Percent_Identity=45.8149779735683, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI17536925, Length=183, Percent_Identity=27.3224043715847, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221330176, Length=229, Percent_Identity=53.7117903930131, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24667703, Length=169, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356335, Length=169, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24667711, Length=169, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 38600; Mature: 38600

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFRQLFDPQSSTYTYLLADPAAREALLIDPVFEQVRRDAALLDELGLRLVATIDTHVHA
CCCHHHCCCCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHCCCEEEEEEECCEEC
DHVTGAWLLKQHTGSAIAISADSGAQGADRYLRDGDRCTFGARYVTVRATPGHTSGCISL
CCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCEEECEEEEEEEECCCCCCCEEEE
VLDDESKAFTGDCLLIRGTGRTDFQQGDPRALYRSVHGRLFTLPAACLLYPAHDYRGLSV
EEECCCCEEECCEEEEECCCCCCCCCCCHHHHHHHHCCEEEECCHHHEEEECCCCCCCEE
TSVAEERRFNPRLGGDLSEDDFAGYMRNLGLAHPRQIDVAVPANLRCGVAASAPDARDAA
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEECEECCCCCCCCCC
DWAPLAYTFAGFWEIDAQWLEDHLTAVQIVDVREPDEFTGPLGHLPGATPIPLGELAARA
CCCCHHHHHHCEEEECHHHHHCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHH
GELARERPIVTVCRAGGRSAQATVLLRNAGFDRVANLGGGMLRWRAEGRIVTDGRA
HHHHHCCCEEEEECCCCCCCEEEEEEECCCHHHHHHCCCCEEEEEECCEEEECCCC
>Mature Secondary Structure
MIFRQLFDPQSSTYTYLLADPAAREALLIDPVFEQVRRDAALLDELGLRLVATIDTHVHA
CCCHHHCCCCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHCCCEEEEEEECCEEC
DHVTGAWLLKQHTGSAIAISADSGAQGADRYLRDGDRCTFGARYVTVRATPGHTSGCISL
CCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCEEECEEEEEEEECCCCCCCEEEE
VLDDESKAFTGDCLLIRGTGRTDFQQGDPRALYRSVHGRLFTLPAACLLYPAHDYRGLSV
EEECCCCEEECCEEEEECCCCCCCCCCCHHHHHHHHCCEEEECCHHHEEEECCCCCCCEE
TSVAEERRFNPRLGGDLSEDDFAGYMRNLGLAHPRQIDVAVPANLRCGVAASAPDARDAA
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEECEECCCCCCCCCC
DWAPLAYTFAGFWEIDAQWLEDHLTAVQIVDVREPDEFTGPLGHLPGATPIPLGELAARA
CCCCHHHHHHCEEEECHHHHHCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHH
GELARERPIVTVCRAGGRSAQATVLLRNAGFDRVANLGGGMLRWRAEGRIVTDGRA
HHHHHCCCEEEEECCCCCCCEEEEEEECCCHHHHHHCCCCEEEEEECCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]