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The map label for this gene is nylB [H]

Identifier: 189353947

GI number: 189353947

Start: 2263658

End: 2265103

Strand: Direct

Name: nylB [H]

Synonym: BMULJ_05200

Alternate gene names: 189353947

Gene position: 2263658-2265103 (Clockwise)

Preceding gene: 189353942

Following gene: 189353949

Centisome position: 91.53

GC content: 71.51

Gene sequence:

>1446_bases
ATGACGATCCCGCTCAAACCGTTGATTCGACGCGGCGTCGCGCTCGCGCTGATCGCCGCGATCGGCTATGCGGGCTATCA
GTTGTCGCGGCTTGCGCCGATCGCGACCGGCTATGCGGCGAAGGCGCTCTGCTCGGGCGTGTTCGTGTCCGGGCGCCCCG
CCGCTTCGGTCATCGACGTCGACATCATGGCCGGCGTGCATCCGCTGCTGAAACTCGTGCGCCCGTCGATCGATGCCGAG
CACCATCGCGCACATGCGACGTTCGCGGGCTTCGCCGCGCGCGACGCCGAATTCCGTCCGGGGCTCGGCTGCACGCTCGC
GCTCGGTCGCGCGGCCGCCGCGCTGCCAGCCGCGTTGCCGCCATTGCCGGCCGCGCCCGCGGCGACCGCCGTGCCGGCAT
CGCTTGCCATCGCCTCCGCCTCCGCGTCGGCCTCATCGGCCGCAACCGCGCCCAACGGCGTCGATATGCGGAAACTGCAC
GCGGCGCTCGATCGCGCATTCGACGAACCGGATCCCGCGCGGCCGCGCCGCACGCGCGCGGTCGTCGTCATGTGGCGCGG
CCACGTGATCGCGGAACGCTACGCGCCCGGCTTCACCGGCGATACGCCGCTGCCCGGCTGGTCGATGACGAAAACCGTCA
CGGCCGTGCTGATCGGGATGCTCGTCGGGCAGCACCGGCTGTCGCCCGACACGGCGGCGCTGCTGCCCGAGTGGCGCGGC
GCCGGCGATCCGCGCGCGGCGATCACGCTCGACGAATTGCTGCGGATGACGAGCGGCCTGCAATTCAACGAGGACTACGA
CGACCCGCTGTCCGACGTCGCCGTGATGCTGTTCACGCAGCGCGACACGGCGCGCTTCGCGTCGAACAAGCCGCTCGCGG
CGCCGCCCGGCACGCGCTGGGACTATTCGAGCGGCACGAGCGAGATCGTCGCGCGCGTGATGCGCGTCGCGCTCGGCGGC
AGCACGGACGACTATCTGTCGTTCCCGCGCCGCGCGTTGTTCGCGCCGCTCGGCATGCGCAGCGCGGTGTTCGAGCCCGA
CGCGTCCGGCACGCTGGCCGCCGCGTCGTTCATGTATGCGAGCGCGCGCGACTGGGCGCGCTTCGGCCAGTTTCTGCTGC
AGGACGGCGTATGGAACGGGCAGCGGCTGCTGCCCGAAGGCTGGGTGCGCTACCTGGCACGCGCGACGCCGCAATCGTCG
CGCGCGGCATTCGGCGCGCATCTGTGGGTCAAGGTGCCGGAACCGTTCGACGACCGCGATCCGCATGCGCCGGCGCTCCC
GGCCGATGCGTTTCATGCGGTCGGTCACGAAGGCCAGTTCGTCAGCGTCGTGCCGAGCCGCGATCTCGTCGTCGTGCGGC
TCGGGCTGTCGCGGCCCGAGTCCGCATGGAATCACGAGGCGTTTCTGGCCCGCGTGCTCGACGCGATACCGGCATCCGGC
ACGTGA

Upstream 100 bases:

>100_bases
CGCGCGACGCGCGCCCTGTCATGCGGCCGCGATTGCCACGCATCGGCCGAACCTGCGACACTGCCGCTCGTTGCCGCCCG
GCACCCGCTCGAGGACACGC

Downstream 100 bases:

>100_bases
CGGCCGCGCGCGAGCGGCGCCGCGTTACGGGTTCGCGCTGCCGGCGTAGGTCTGGAAGCCTTCGCGCGTCGCGAGACGAT
CGGCATAGCGCTTCACGGCC

Product: putative beta-lactamase

Products: NA

Alternate protein names: Nylon oligomers-degrading enzyme EII [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTIPLKPLIRRGVALALIAAIGYAGYQLSRLAPIATGYAAKALCSGVFVSGRPAASVIDVDIMAGVHPLLKLVRPSIDAE
HHRAHATFAGFAARDAEFRPGLGCTLALGRAAAALPAALPPLPAAPAATAVPASLAIASASASASSAATAPNGVDMRKLH
AALDRAFDEPDPARPRRTRAVVVMWRGHVIAERYAPGFTGDTPLPGWSMTKTVTAVLIGMLVGQHRLSPDTAALLPEWRG
AGDPRAAITLDELLRMTSGLQFNEDYDDPLSDVAVMLFTQRDTARFASNKPLAAPPGTRWDYSSGTSEIVARVMRVALGG
STDDYLSFPRRALFAPLGMRSAVFEPDASGTLAAASFMYASARDWARFGQFLLQDGVWNGQRLLPEGWVRYLARATPQSS
RAAFGAHLWVKVPEPFDDRDPHAPALPADAFHAVGHEGQFVSVVPSRDLVVVRLGLSRPESAWNHEAFLARVLDAIPASG
T

Sequences:

>Translated_481_residues
MTIPLKPLIRRGVALALIAAIGYAGYQLSRLAPIATGYAAKALCSGVFVSGRPAASVIDVDIMAGVHPLLKLVRPSIDAE
HHRAHATFAGFAARDAEFRPGLGCTLALGRAAAALPAALPPLPAAPAATAVPASLAIASASASASSAATAPNGVDMRKLH
AALDRAFDEPDPARPRRTRAVVVMWRGHVIAERYAPGFTGDTPLPGWSMTKTVTAVLIGMLVGQHRLSPDTAALLPEWRG
AGDPRAAITLDELLRMTSGLQFNEDYDDPLSDVAVMLFTQRDTARFASNKPLAAPPGTRWDYSSGTSEIVARVMRVALGG
STDDYLSFPRRALFAPLGMRSAVFEPDASGTLAAASFMYASARDWARFGQFLLQDGVWNGQRLLPEGWVRYLARATPQSS
RAAFGAHLWVKVPEPFDDRDPHAPALPADAFHAVGHEGQFVSVVPSRDLVVVRLGLSRPESAWNHEAFLARVLDAIPASG
T
>Mature_480_residues
TIPLKPLIRRGVALALIAAIGYAGYQLSRLAPIATGYAAKALCSGVFVSGRPAASVIDVDIMAGVHPLLKLVRPSIDAEH
HRAHATFAGFAARDAEFRPGLGCTLALGRAAAALPAALPPLPAAPAATAVPASLAIASASASASSAATAPNGVDMRKLHA
ALDRAFDEPDPARPRRTRAVVVMWRGHVIAERYAPGFTGDTPLPGWSMTKTVTAVLIGMLVGQHRLSPDTAALLPEWRGA
GDPRAAITLDELLRMTSGLQFNEDYDDPLSDVAVMLFTQRDTARFASNKPLAAPPGTRWDYSSGTSEIVARVMRVALGGS
TDDYLSFPRRALFAPLGMRSAVFEPDASGTLAAASFMYASARDWARFGQFLLQDGVWNGQRLLPEGWVRYLARATPQSSR
AAFGAHLWVKVPEPFDDRDPHAPALPADAFHAVGHEGQFVSVVPSRDLVVVRLGLSRPESAWNHEAFLARVLDAIPASGT

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.1.46 [H]

Molecular weight: Translated: 51078; Mature: 50947

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPLKPLIRRGVALALIAAIGYAGYQLSRLAPIATGYAAKALCSGVFVSGRPAASVIDV
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEH
DIMAGVHPLLKLVRPSIDAEHHRAHATFAGFAARDAEFRPGLGCTLALGRAAAALPAALP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
PLPAAPAATAVPASLAIASASASASSAATAPNGVDMRKLHAALDRAFDEPDPARPRRTRA
CCCCCCCCHHCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEE
VVVMWRGHVIAERYAPGFTGDTPLPGWSMTKTVTAVLIGMLVGQHRLSPDTAALLPEWRG
EEEEECCEEEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCC
AGDPRAAITLDELLRMTSGLQFNEDYDDPLSDVAVMLFTQRDTARFASNKPLAAPPGTRW
CCCCCCEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCC
DYSSGTSEIVARVMRVALGGSTDDYLSFPRRALFAPLGMRSAVFEPDASGTLAAASFMYA
CCCCCHHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHH
SARDWARFGQFLLQDGVWNGQRLLPEGWVRYLARATPQSSRAAFGAHLWVKVPEPFDDRD
HHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHCCCCCCCHHCCEEEEEECCCCCCCCC
PHAPALPADAFHAVGHEGQFVSVVPSRDLVVVRLGLSRPESAWNHEAFLARVLDAIPASG
CCCCCCCCHHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
T
C
>Mature Secondary Structure 
TIPLKPLIRRGVALALIAAIGYAGYQLSRLAPIATGYAAKALCSGVFVSGRPAASVIDV
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEH
DIMAGVHPLLKLVRPSIDAEHHRAHATFAGFAARDAEFRPGLGCTLALGRAAAALPAALP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
PLPAAPAATAVPASLAIASASASASSAATAPNGVDMRKLHAALDRAFDEPDPARPRRTRA
CCCCCCCCHHCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEE
VVVMWRGHVIAERYAPGFTGDTPLPGWSMTKTVTAVLIGMLVGQHRLSPDTAALLPEWRG
EEEEECCEEEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCC
AGDPRAAITLDELLRMTSGLQFNEDYDDPLSDVAVMLFTQRDTARFASNKPLAAPPGTRW
CCCCCCEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCC
DYSSGTSEIVARVMRVALGGSTDDYLSFPRRALFAPLGMRSAVFEPDASGTLAAASFMYA
CCCCCHHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHH
SARDWARFGQFLLQDGVWNGQRLLPEGWVRYLARATPQSSRAAFGAHLWVKVPEPFDDRD
HHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHCCCCCCCHHCCEEEEEECCCCCCCCC
PHAPALPADAFHAVGHEGQFVSVVPSRDLVVVRLGLSRPESAWNHEAFLARVLDAIPASG
CCCCCCCCHHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6646204; 6389532; 2512123 [H]