Click here to switch to the map view.

The map label for this gene is str [H]

Identifier: 189353942

GI number: 189353942

Start: 2259568

End: 2260365

Strand: Direct

Name: str [H]

Synonym: BMULJ_05195

Alternate gene names: 189353942

Gene position: 2259568-2260365 (Clockwise)

Preceding gene: 189353939

Following gene: 189353947

Centisome position: 91.36

GC content: 69.8

Gene sequence:

>798_bases
ATGTTCGCTGCGCATCTTCGTTCGTGGAGCCTCACGCCCGACGGCGGTCCGATCCTGACCGCCAGCGGCGGCGTATTGCC
GGTCGTCTGGCGCGGACGGCCTGCGATGCTGAAGGTCGCGACCTGCGAAGAAGAGCGGCGCGGCAACGCGCTGATGACAT
GGTGGGACGGACACGGCGCCGCGCAGGTATGGGCGCACGACGACGACGCGATCCTGCTCGAGCGTGCGCAGCCGCAACCG
GCGCTCGCCGACTTTTCGGCGTCCGGCCACGACGACGATGCAATACGGATCGCATGCGACGTCGTCGCGCAGCTGCACGC
CTATCGTGCGCCGGACCCGCCGCCGCTCGTCGCGCTGCGCGACTGGTTCGCGTCGCTGCTGGCGTCCGATGCGACCGACG
CGATACTGCGCCGGTCGCAAGCGACGGCGGCCGCGCTGCTTGCCGAACCGCCCGTCGACGAAGCGCTGCTGCACGGCGAC
ATCCATCACCGCAACGTGCTGCACTTCGGCGATCGCGGCTGGCGCGCGATCGATCCGAAAGCACTGCGCGGCGCACGCGC
CTTCGACTACGCGAACCTGTTCTGCAATCCGTCGCACGACATCGCGGTCGATCGCACGCGCTTCGAACGTCGCGTCGCGA
TCGTCGCCGATGCCGCGCGGCTCGATCCGCGCACGCTGCTGCGCTGGATTCTCGCGTGGTCCGGGCTGTCGGCGATCTGG
CTGATCGAAGACGACGAACCGGCAGAGACGCGGCTGCAGGTCGCCGCGCTCGCCGCACACGCGCTCGATTCGCGCTGA

Upstream 100 bases:

>100_bases
GGGCTGGCTAAATTTTATTGAGGAAAGCACGCCGCATCGTCGGACACGGCGGCTCATGCACCGTCGCGCGGATACGCCGG
TTCGCCTGTACCATTTCCGC

Downstream 100 bases:

>100_bases
CGATGCGCGGCGCCGCCCGCGCGCGCGGCAATAAAAAACCCGCCGGCAAGCGGCGGGTTTCCGTGTACGACTGCTGCGGC
GCTCAGCGGGCCGGGTTCAG

Product: aminoglycoside/hydroxyurea antibiotic resistance kinase

Products: NA

Alternate protein names: Streptomycin 3''-phosphotransferase; SPH [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MFAAHLRSWSLTPDGGPILTASGGVLPVVWRGRPAMLKVATCEEERRGNALMTWWDGHGAAQVWAHDDDAILLERAQPQP
ALADFSASGHDDDAIRIACDVVAQLHAYRAPDPPPLVALRDWFASLLASDATDAILRRSQATAAALLAEPPVDEALLHGD
IHHRNVLHFGDRGWRAIDPKALRGARAFDYANLFCNPSHDIAVDRTRFERRVAIVADAARLDPRTLLRWILAWSGLSAIW
LIEDDEPAETRLQVAALAAHALDSR

Sequences:

>Translated_265_residues
MFAAHLRSWSLTPDGGPILTASGGVLPVVWRGRPAMLKVATCEEERRGNALMTWWDGHGAAQVWAHDDDAILLERAQPQP
ALADFSASGHDDDAIRIACDVVAQLHAYRAPDPPPLVALRDWFASLLASDATDAILRRSQATAAALLAEPPVDEALLHGD
IHHRNVLHFGDRGWRAIDPKALRGARAFDYANLFCNPSHDIAVDRTRFERRVAIVADAARLDPRTLLRWILAWSGLSAIW
LIEDDEPAETRLQVAALAAHALDSR
>Mature_265_residues
MFAAHLRSWSLTPDGGPILTASGGVLPVVWRGRPAMLKVATCEEERRGNALMTWWDGHGAAQVWAHDDDAILLERAQPQP
ALADFSASGHDDDAIRIACDVVAQLHAYRAPDPPPLVALRDWFASLLASDATDAILRRSQATAAALLAEPPVDEALLHGD
IHHRNVLHFGDRGWRAIDPKALRGARAFDYANLFCNPSHDIAVDRTRFERRVAIVADAARLDPRTLLRWILAWSGLSAIW
LIEDDEPAETRLQVAALAAHALDSR

Specific function: The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation [H]

COG id: COG3570

COG function: function code V; Streptomycin 6-kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aminoglycoside phosphotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006748 [H]

Pfam domain/function: PF04655 APH_6_hur [H]

EC number: =2.7.1.87 [H]

Molecular weight: Translated: 29091; Mature: 29091

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAAHLRSWSLTPDGGPILTASGGVLPVVWRGRPAMLKVATCEEERRGNALMTWWDGHGA
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCEEEEEECCHHHCCCEEEEEECCCCE
AQVWAHDDDAILLERAQPQPALADFSASGHDDDAIRIACDVVAQLHAYRAPDPPPLVALR
EEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHH
DWFASLLASDATDAILRRSQATAAALLAEPPVDEALLHGDIHHRNVLHFGDRGWRAIDPK
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEECCCCCEECCHH
ALRGARAFDYANLFCNPSHDIAVDRTRFERRVAIVADAARLDPRTLLRWILAWSGLSAIW
HHCCCCCCCHHHEEECCCCCEEECHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCEEE
LIEDDEPAETRLQVAALAAHALDSR
EEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFAAHLRSWSLTPDGGPILTASGGVLPVVWRGRPAMLKVATCEEERRGNALMTWWDGHGA
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCEEEEEECCHHHCCCEEEEEECCCCE
AQVWAHDDDAILLERAQPQPALADFSASGHDDDAIRIACDVVAQLHAYRAPDPPPLVALR
EEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHH
DWFASLLASDATDAILRRSQATAAALLAEPPVDEALLHGDIHHRNVLHFGDRGWRAIDPK
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEECCCCCEECCHH
ALRGARAFDYANLFCNPSHDIAVDRTRFERRVAIVADAARLDPRTLLRWILAWSGLSAIW
HHCCCCCCCHHHEEECCCCCEEECHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCEEE
LIEDDEPAETRLQVAALAAHALDSR
EEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3889831 [H]