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The map label for this gene is dhaR [H]

Identifier: 189353917

GI number: 189353917

Start: 2231630

End: 2232265

Strand: Direct

Name: dhaR [H]

Synonym: BMULJ_05169

Alternate gene names: 189353917

Gene position: 2231630-2232265 (Clockwise)

Preceding gene: 189353914

Following gene: 189353918

Centisome position: 90.23

GC content: 68.71

Gene sequence:

>636_bases
ATGGACACATGCACCGAACTGCCGCGCCGTCGCGGCAGGCCGCCGAAGCAGCACGACGACCTCGTCGCGACGCGCGACAT
GCTGCTGCGCACGGGCCTCGAGATCCTGACCGAAAAGGGTTTTTCGTCGACGGGGCTCGATGAAATCCTCGGACGCGCCG
GCGTGCCGAAGGGCTCGTTCTATCACTACTTCGACAGCAAGGAAGCGTTTGGCCTCGCGCTGATCGACCGCTATGCGGAA
TTCTTCGCGCGCAAGCTCGATCGCCACTTCGGCGACACCAAACGCTCGCCGCTGCAGCGCGTGCGCGCGTTCGTCGACGA
TGCGCGCGACGGGATGGCGCGCTACGACTACCGGCGCGGCTGCCTGATCGGCAATCTCGGCCAGGAGATGGGCGCGCTGC
CGGAAACCTTCCGCGCGCGGCTGCAGGCGACGTTCGAAGACTGGCAGCGCCGCCTCGCCGACTGCCTGCGCGGCGCGCAG
CAGGCCGGCGAACTGTCGCACGCGGCCGCGCCGGCCGAGCTCGCCGCGTTTTTCTGGATCGGCTGGGAAGGCGCGGTGCT
GCGCGCGAAGCTGGAACGCCGCGACGCGCCGCTTGTGCTGTTCGCGCAGCATTTCTTCGACGCGCTGCGTCGCTGA

Upstream 100 bases:

>100_bases
TTTTCACCGCGATAAGGTTTTTTAATCGCGGGTTAACGCGGGTACGGATCGACGCCGCGCGCCGTTTTATTTTTGAGACG
AACGGTCTATTATTCGACGC

Downstream 100 bases:

>100_bases
ATCTTTTCATTGACTGGGCGACCGCGCCAGAAAGGAGAACACGTGTTCCACGGCATCCTGATCGACAAGGACGACACCGG
CCAGCGCACGCGCGTGCAAA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MDTCTELPRRRGRPPKQHDDLVATRDMLLRTGLEILTEKGFSSTGLDEILGRAGVPKGSFYHYFDSKEAFGLALIDRYAE
FFARKLDRHFGDTKRSPLQRVRAFVDDARDGMARYDYRRGCLIGNLGQEMGALPETFRARLQATFEDWQRRLADCLRGAQ
QAGELSHAAAPAELAAFFWIGWEGAVLRAKLERRDAPLVLFAQHFFDALRR

Sequences:

>Translated_211_residues
MDTCTELPRRRGRPPKQHDDLVATRDMLLRTGLEILTEKGFSSTGLDEILGRAGVPKGSFYHYFDSKEAFGLALIDRYAE
FFARKLDRHFGDTKRSPLQRVRAFVDDARDGMARYDYRRGCLIGNLGQEMGALPETFRARLQATFEDWQRRLADCLRGAQ
QAGELSHAAAPAELAAFFWIGWEGAVLRAKLERRDAPLVLFAQHFFDALRR
>Mature_211_residues
MDTCTELPRRRGRPPKQHDDLVATRDMLLRTGLEILTEKGFSSTGLDEILGRAGVPKGSFYHYFDSKEAFGLALIDRYAE
FFARKLDRHFGDTKRSPLQRVRAFVDDARDGMARYDYRRGCLIGNLGQEMGALPETFRARLQATFEDWQRRLADCLRGAQ
QAGELSHAAAPAELAAFFWIGWEGAVLRAKLERRDAPLVLFAQHFFDALRR

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=182, Percent_Identity=31.8681318681319, Blast_Score=97, Evalue=6e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24083; Mature: 24083

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTCTELPRRRGRPPKQHDDLVATRDMLLRTGLEILTEKGFSSTGLDEILGRAGVPKGSF
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCE
YHYFDSKEAFGLALIDRYAEFFARKLDRHFGDTKRSPLQRVRAFVDDARDGMARYDYRRG
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
CLIGNLGQEMGALPETFRARLQATFEDWQRRLADCLRGAQQAGELSHAAAPAELAAFFWI
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GWEGAVLRAKLERRDAPLVLFAQHFFDALRR
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDTCTELPRRRGRPPKQHDDLVATRDMLLRTGLEILTEKGFSSTGLDEILGRAGVPKGSF
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCE
YHYFDSKEAFGLALIDRYAEFFARKLDRHFGDTKRSPLQRVRAFVDDARDGMARYDYRRG
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
CLIGNLGQEMGALPETFRARLQATFEDWQRRLADCLRGAQQAGELSHAAAPAELAAFFWI
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GWEGAVLRAKLERRDAPLVLFAQHFFDALRR
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]