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The map label for this gene is ceoA [H]

Identifier: 189353901

GI number: 189353901

Start: 2211658

End: 2212875

Strand: Reverse

Name: ceoA [H]

Synonym: BMULJ_05153

Alternate gene names: 189353901

Gene position: 2212875-2211658 (Counterclockwise)

Preceding gene: 189353902

Following gene: 189353900

Centisome position: 89.48

GC content: 69.95

Gene sequence:

>1218_bases
ATGGCCATCCTACGCACCTCCCGCTCCCGCATCGCGACCGCTGCGGTCGCGACGCTCGCCGTCGTCGGCCTCGGGACGTT
CGGCGCGATGCGCGTCAACGCGAACGCGCCCGAGAAGGCCGCCGCCCCGCTGACGGAAGTCGACGTCGCGACGGTCGTGC
CGCAGACCGTGACCGACTGGCAAAGCTATTCGGGCCGCCTCGAGGCGGTCGAGAAGGTCGACGTGCGCCCGCAGGTATCG
GGCACGATCGTCGCGGTGAACTTCAAGGACGGCGCGCTCGTGAAGAAGGGCGACGTGCTGTTCGTGATCGATCCGCGCCC
GTACCAGGCCGAAGTCGACCGCGCCGCCGCGCAGCTCGCGGCAGCGCAGGCACGCAACGGCTACGCGCAGAGCGACTGGC
AGCGCGCGCAGCGGCTGATCGGCGACAACGCGATCGCGAAGCGCGACTACGACGAGAAGCAGAACGCCGCGCGCGAAGCG
GCCGCGAACCTCAAGGCGGCCGAAGCCGCGCTCGAGACCGCGCGCATCAATCTCGGCTATACGCGGATCACGGCGCCCGT
GTCGGGCCGCGTGTCGCGCGCGGAGATCACGCTCGGCAACGTCGTGTCGGCCGGTGCATCGGCGCCGCCGCTCACGACGC
TCGTGTCGGTGTCGCCGATCTACGCGTCGTTCGACGCGGACGAGCAGACCTATCTGCAATACATCAATGGCGCGCGCAAC
GGCCGCAAGGTGCCGGTCGAACTCGGCCTCGCCAACGAAACCGGCTATTCGCGCAGCGGCGAGATCGATTCGGTCGACAA
CCGGCTCGATACGTCGTCCGGCACGATCCGCGTGCGTGCGCGCTTCGACAACGCGGACGGCACGCTCGTCCCCGGCCTGT
ATGCACGCGTGAAGGTGGGCGGCAGCGCGCCGCATGCGGCGCTGCTCGTCGACGATGCGGCGATCAACACCGATCAGGAC
AAGAAGTTCGTGTTCGTCGTCGATCAGCAGGGCCGCGTGTCGTATCGCGAAGTGCAGCCGGGCATGCAGCACGGCAACCA
GCGCGTGATCGTGAGCGGCCTGGCCGCCGGCGACCGCGTGATCGTGAACGGCACGCAGCGCGTGCGCCCCGGCGAGCAGG
TGAAGCCGCACATGGTGCCGATGACGGGCGGCGACGCGCCGTCGGCGCCGATCGCGAGCACGGCGAAGCCGGCCGCTCCG
GCGAAGGCGGATTCGTAA

Upstream 100 bases:

>100_bases
GCCTTCGACGAAGCCGTGCGCTTCTTCCAGTGCCGCTTCCAGGCGCGCCAGCCGAATCGCAACGAATAACCAATCCAATC
CACGCTTACCGGAGATCTAC

Downstream 100 bases:

>100_bases
GCGGAGCGCCGCTTCGCATCCGCGTTCAACCAGACAGAGTCACCCATGAACATATCCAAATTCTTTATCGACCGGCCGAT
CTTCGCAGGGGTGCTATCGG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAILRTSRSRIATAAVATLAVVGLGTFGAMRVNANAPEKAAAPLTEVDVATVVPQTVTDWQSYSGRLEAVEKVDVRPQVS
GTIVAVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAAAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREA
AANLKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAPPLTTLVSVSPIYASFDADEQTYLQYINGARN
GRKVPVELGLANETGYSRSGEIDSVDNRLDTSSGTIRVRARFDNADGTLVPGLYARVKVGGSAPHAALLVDDAAINTDQD
KKFVFVVDQQGRVSYREVQPGMQHGNQRVIVSGLAAGDRVIVNGTQRVRPGEQVKPHMVPMTGGDAPSAPIASTAKPAAP
AKADS

Sequences:

>Translated_405_residues
MAILRTSRSRIATAAVATLAVVGLGTFGAMRVNANAPEKAAAPLTEVDVATVVPQTVTDWQSYSGRLEAVEKVDVRPQVS
GTIVAVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAAAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREA
AANLKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAPPLTTLVSVSPIYASFDADEQTYLQYINGARN
GRKVPVELGLANETGYSRSGEIDSVDNRLDTSSGTIRVRARFDNADGTLVPGLYARVKVGGSAPHAALLVDDAAINTDQD
KKFVFVVDQQGRVSYREVQPGMQHGNQRVIVSGLAAGDRVIVNGTQRVRPGEQVKPHMVPMTGGDAPSAPIASTAKPAAP
AKADS
>Mature_404_residues
AILRTSRSRIATAAVATLAVVGLGTFGAMRVNANAPEKAAAPLTEVDVATVVPQTVTDWQSYSGRLEAVEKVDVRPQVSG
TIVAVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAAAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREAA
ANLKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAPPLTTLVSVSPIYASFDADEQTYLQYINGARNG
RKVPVELGLANETGYSRSGEIDSVDNRLDTSSGTIRVRARFDNADGTLVPGLYARVKVGGSAPHAALLVDDAAINTDQDK
KFVFVVDQQGRVSYREVQPGMQHGNQRVIVSGLAAGDRVIVNGTQRVRPGEQVKPHMVPMTGGDAPSAPIASTAKPAAPA
KADS

Specific function: Part of a multidrug resistance efflux system that confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=360, Percent_Identity=35, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082036, Length=335, Percent_Identity=31.6417910447761, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1786668, Length=370, Percent_Identity=34.8648648648649, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789665, Length=351, Percent_Identity=34.1880341880342, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI87081796, Length=319, Percent_Identity=28.8401253918495, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081951, Length=259, Percent_Identity=32.4324324324324, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789637, Length=141, Percent_Identity=34.0425531914894, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42710; Mature: 42579

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILRTSRSRIATAAVATLAVVGLGTFGAMRVNANAPEKAAAPLTEVDVATVVPQTVTDW
CCEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCHHCHHHHHCCCHHHHH
QSYSGRLEAVEKVDVRPQVSGTIVAVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLA
HHCCCCEEHHHHCCCCCCCCCEEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHH
AAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREAAANLKAAEAALETARINLGY
HHHHHCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCE
TRITAPVSGRVSRAEITLGNVVSAGASAPPLTTLVSVSPIYASFDADEQTYLQYINGARN
EEEECCCCCCCEEEEEEECHHHHCCCCCCCCEEEEEECCEEEECCCCHHHHHHHHHCCCC
GRKVPVELGLANETGYSRSGEIDSVDNRLDTSSGTIRVRARFDNADGTLVPGLYARVKVG
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEC
GSAPHAALLVDDAAINTDQDKKFVFVVDQQGRVSYREVQPGMQHGNQRVIVSGLAAGDRV
CCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHCCCHHHCCCCEEEEEEECCCCEE
IVNGTQRVRPGEQVKPHMVPMTGGDAPSAPIASTAKPAAPAKADS
EECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AILRTSRSRIATAAVATLAVVGLGTFGAMRVNANAPEKAAAPLTEVDVATVVPQTVTDW
CEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCHHCHHHHHCCCHHHHH
QSYSGRLEAVEKVDVRPQVSGTIVAVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLA
HHCCCCEEHHHHCCCCCCCCCEEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHH
AAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREAAANLKAAEAALETARINLGY
HHHHHCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCE
TRITAPVSGRVSRAEITLGNVVSAGASAPPLTTLVSVSPIYASFDADEQTYLQYINGARN
EEEECCCCCCCEEEEEEECHHHHCCCCCCCCEEEEEECCEEEECCCCHHHHHHHHHCCCC
GRKVPVELGLANETGYSRSGEIDSVDNRLDTSSGTIRVRARFDNADGTLVPGLYARVKVG
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEC
GSAPHAALLVDDAAINTDQDKKFVFVVDQQGRVSYREVQPGMQHGNQRVIVSGLAAGDRV
CCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHCCCHHHCCCCEEEEEEECCCCEE
IVNGTQRVRPGEQVKPHMVPMTGGDAPSAPIASTAKPAAPAKADS
EECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]