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The map label for this gene is gudP [H]

Identifier: 189353876

GI number: 189353876

Start: 2183209

End: 2184585

Strand: Direct

Name: gudP [H]

Synonym: BMULJ_05128

Alternate gene names: 189353876

Gene position: 2183209-2184585 (Clockwise)

Preceding gene: 189353874

Following gene: 189353877

Centisome position: 88.28

GC content: 67.9

Gene sequence:

>1377_bases
GTGACGAATCAGACTCCCTCTCGCGACCTCCCGATCGACCTCGCGCGCACCGAACGCCGAACCGCGGTGCGCTACTGGAT
CCTGGCGATGCTGTTCGTCGTCACGACGCTGAACTATGCGGACCGCGCGACGCTGTCGATCACCGGCACGCCGATCCGTC
AGGCGTTCGGCATCGATCCGGTGACGATGGGCTACATCTTCTCCGCGTTCAGCTGGGCGTACGTGCTCGCGCAATTGCCG
AGCGGCTGGCTGCTCGACCGCTTCGGCGCACGGCGCGTATATGCGGCAAGCATCTTCCTGTGGTCGGCGTTCACGCTGCT
GCAGAGCACGATCGGCCTCGGCGGTAGCGCGGCGTTCGCGGTCGTCGCGCTGTTCGCGATGCGCTTCGCGGTCGGCATCG
CGGAGGCGCCCGCGTTTCCGGCGAACGCGAAGGTCGTCGCGAGCTGGTTCCCGACCGCCGAGCGCGGCACCGCGTCGGCG
ATCTTCAACGCCGCGCAGTATTTCGCGGCCGTCGTGTTCTCGCCGCTGATGGCGTGGCTCACGCACGCGTACGGCTGGCA
TCACGTCTATCTGTGGCTCGGCCTCGCCGGCATCGCGCTCGCGCTGCTGTGGCTGCGCGTCGTGAAGGACCCGGCCGACC
ATCCGGCCGTGAACCGCGCGGAGCTCGAGCATATCGAGCAGGGCGGCGGCGTCGTACGCGCGGCCGCGCGCCGCGACGGC
ACGCGCGCCGAAGGCTCGCGCGTCGCCGGCTGGTACTACGTGCGCCAGCTGCTGTCGAACCGGATGCTGATCGGCGTCTA
TATCGGTCAGTACTGCGTGAACGTGCTGACCTACTTCTTCCTCACGTGGTTTCCGATCTACCTCGTGCAGGCGCGCGGGA
TGTCGCTGCTGAAGGCCGGCTTCATGACGTCGCTGCCGGCGGTCTGCGGCTTCCTCGGCGGCGTGCTCGGCGGGATGCTG
TCGGACGCGCTGATTCGCCGCGGCGTGTCGCTGACGCTCGCGCGCAAGATCCCGATCGTCGGCGGGATGCTGCTGTCGAT
GGTGATCATCGGCTGCAACTACGTCGACAGCGAAGCGCTCGTGATCGTGCTGATGGCCGTGTCGTTCTTCGGCAAGGGGA
TCGGCTCGCTCGGCTGGGCGGTGGTCGCGGACACCGCGCCGAAAGAGGCGATCGGCCTGTCGGGCAGCCTGTTCAACATG
TTCGGCAACACGGCCGGCATCGTCGCGCCGATCGCGATCGGCTACCTCGTCGGCGCGAGCGGCTCGTTCAACGGCGCGCT
CGTGTTCGTCGGCCTGAACGCGCTCGTCACCGTGTTCAGCTATCTCGTGATCGTGAAGGACATCCGGCGCGTCGAGTTGC
GCCATCAGGCGGCCTGA

Upstream 100 bases:

>100_bases
GATGACTAGCAGCCGGATAACCAAGGGGAAACCCGAACTTTGCACGCCAGCATGCGGACCCTACACTGCTCGCCATGTCA
TACGACGACGTACATTCAAA

Downstream 100 bases:

>100_bases
GCGCGCGTCGCGCCAGGCGGCGGGCCGGCCGGCGCTTAACCATCACTCGGCCGTCGCCCGTACGCCACCGCATCGCCCGC
CCTGCACCGCGACGCTTACC

Product: glucarate transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTNQTPSRDLPIDLARTERRTAVRYWILAMLFVVTTLNYADRATLSITGTPIRQAFGIDPVTMGYIFSAFSWAYVLAQLP
SGWLLDRFGARRVYAASIFLWSAFTLLQSTIGLGGSAAFAVVALFAMRFAVGIAEAPAFPANAKVVASWFPTAERGTASA
IFNAAQYFAAVVFSPLMAWLTHAYGWHHVYLWLGLAGIALALLWLRVVKDPADHPAVNRAELEHIEQGGGVVRAAARRDG
TRAEGSRVAGWYYVRQLLSNRMLIGVYIGQYCVNVLTYFFLTWFPIYLVQARGMSLLKAGFMTSLPAVCGFLGGVLGGML
SDALIRRGVSLTLARKIPIVGGMLLSMVIIGCNYVDSEALVIVLMAVSFFGKGIGSLGWAVVADTAPKEAIGLSGSLFNM
FGNTAGIVAPIAIGYLVGASGSFNGALVFVGLNALVTVFSYLVIVKDIRRVELRHQAA

Sequences:

>Translated_458_residues
MTNQTPSRDLPIDLARTERRTAVRYWILAMLFVVTTLNYADRATLSITGTPIRQAFGIDPVTMGYIFSAFSWAYVLAQLP
SGWLLDRFGARRVYAASIFLWSAFTLLQSTIGLGGSAAFAVVALFAMRFAVGIAEAPAFPANAKVVASWFPTAERGTASA
IFNAAQYFAAVVFSPLMAWLTHAYGWHHVYLWLGLAGIALALLWLRVVKDPADHPAVNRAELEHIEQGGGVVRAAARRDG
TRAEGSRVAGWYYVRQLLSNRMLIGVYIGQYCVNVLTYFFLTWFPIYLVQARGMSLLKAGFMTSLPAVCGFLGGVLGGML
SDALIRRGVSLTLARKIPIVGGMLLSMVIIGCNYVDSEALVIVLMAVSFFGKGIGSLGWAVVADTAPKEAIGLSGSLFNM
FGNTAGIVAPIAIGYLVGASGSFNGALVFVGLNALVTVFSYLVIVKDIRRVELRHQAA
>Mature_457_residues
TNQTPSRDLPIDLARTERRTAVRYWILAMLFVVTTLNYADRATLSITGTPIRQAFGIDPVTMGYIFSAFSWAYVLAQLPS
GWLLDRFGARRVYAASIFLWSAFTLLQSTIGLGGSAAFAVVALFAMRFAVGIAEAPAFPANAKVVASWFPTAERGTASAI
FNAAQYFAAVVFSPLMAWLTHAYGWHHVYLWLGLAGIALALLWLRVVKDPADHPAVNRAELEHIEQGGGVVRAAARRDGT
RAEGSRVAGWYYVRQLLSNRMLIGVYIGQYCVNVLTYFFLTWFPIYLVQARGMSLLKAGFMTSLPAVCGFLGGVLGGMLS
DALIRRGVSLTLARKIPIVGGMLLSMVIIGCNYVDSEALVIVLMAVSFFGKGIGSLGWAVVADTAPKEAIGLSGSLFNMF
GNTAGIVAPIAIGYLVGASGSFNGALVFVGLNALVTVFSYLVIVKDIRRVELRHQAA

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI21322234, Length=392, Percent_Identity=26.2755102040816, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI9966811, Length=388, Percent_Identity=26.0309278350515, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI9945322, Length=367, Percent_Identity=27.2479564032698, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI4885441, Length=393, Percent_Identity=25.6997455470738, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI6912666, Length=378, Percent_Identity=24.8677248677249, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031955, Length=281, Percent_Identity=24.9110320284698, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI223718438, Length=196, Percent_Identity=29.5918367346939, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI148743791, Length=377, Percent_Identity=23.6074270557029, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI154350196, Length=421, Percent_Identity=24.9406175771971, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI154800443, Length=483, Percent_Identity=18.8405797101449, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI256219598, Length=396, Percent_Identity=24.2424242424242, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI4503847, Length=396, Percent_Identity=24.2424242424242, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI256219483, Length=396, Percent_Identity=24.2424242424242, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI148728191, Length=312, Percent_Identity=22.4358974358974, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI256219543, Length=307, Percent_Identity=24.7557003257329, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789152, Length=440, Percent_Identity=60.9090909090909, Blast_Score=575, Evalue=1e-165,
Organism=Escherichia coli, GI1789515, Length=441, Percent_Identity=55.5555555555556, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI87082320, Length=443, Percent_Identity=40.4063205417607, Blast_Score=350, Evalue=8e-98,
Organism=Escherichia coli, GI2367379, Length=452, Percent_Identity=28.9823008849558, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI2367193, Length=329, Percent_Identity=27.355623100304, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788573, Length=451, Percent_Identity=23.5033259423503, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=449, Percent_Identity=28.5077951002227, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI115533554, Length=451, Percent_Identity=27.7161862527716, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17552542, Length=377, Percent_Identity=25.4641909814324, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193205400, Length=275, Percent_Identity=23.6363636363636, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560030, Length=368, Percent_Identity=23.0978260869565, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32565914, Length=291, Percent_Identity=21.6494845360825, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32565916, Length=281, Percent_Identity=22.4199288256228, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=424, Percent_Identity=22.1698113207547, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997452, Length=348, Percent_Identity=24.1379310344828, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=380, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=380, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25151055, Length=245, Percent_Identity=23.265306122449, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=320, Percent_Identity=24.375, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=276, Percent_Identity=24.6376811594203, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193208223, Length=373, Percent_Identity=23.8605898123324, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71989129, Length=262, Percent_Identity=28.6259541984733, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71991453, Length=390, Percent_Identity=21.025641025641, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=390, Percent_Identity=21.025641025641, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641682, Length=421, Percent_Identity=26.3657957244656, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45550460, Length=425, Percent_Identity=26.5882352941176, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24655255, Length=379, Percent_Identity=27.4406332453826, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24654215, Length=453, Percent_Identity=24.9448123620309, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583789, Length=419, Percent_Identity=23.8663484486874, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI19922400, Length=366, Percent_Identity=26.5027322404372, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24639764, Length=384, Percent_Identity=25.2604166666667, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573299, Length=408, Percent_Identity=25, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24648416, Length=384, Percent_Identity=25, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21356189, Length=384, Percent_Identity=25, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI62484226, Length=370, Percent_Identity=24.8648648648649, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573708, Length=439, Percent_Identity=24.1457858769932, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573707, Length=439, Percent_Identity=24.1457858769932, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20130167, Length=408, Percent_Identity=25.2450980392157, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24580790, Length=399, Percent_Identity=24.5614035087719, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24584153, Length=381, Percent_Identity=24.1469816272966, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI20130135, Length=411, Percent_Identity=21.8978102189781, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24655271, Length=411, Percent_Identity=21.8978102189781, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24658658, Length=409, Percent_Identity=22.9828850855746, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550364, Length=442, Percent_Identity=24.2081447963801, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20129235, Length=401, Percent_Identity=24.9376558603491, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24658674, Length=383, Percent_Identity=24.8041775456919, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19920686, Length=418, Percent_Identity=23.9234449760766, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221474708, Length=298, Percent_Identity=25.1677852348993, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49406; Mature: 49274

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQTPSRDLPIDLARTERRTAVRYWILAMLFVVTTLNYADRATLSITGTPIRQAFGIDP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCH
VTMGYIFSAFSWAYVLAQLPSGWLLDRFGARRVYAASIFLWSAFTLLQSTIGLGGSAAFA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VVALFAMRFAVGIAEAPAFPANAKVVASWFPTAERGTASAIFNAAQYFAAVVFSPLMAWL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
THAYGWHHVYLWLGLAGIALALLWLRVVKDPADHPAVNRAELEHIEQGGGVVRAAARRDG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEHHHCCC
TRAEGSRVAGWYYVRQLLSNRMLIGVYIGQYCVNVLTYFFLTWFPIYLVQARGMSLLKAG
CCCCCCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FMTSLPAVCGFLGGVLGGMLSDALIRRGVSLTLARKIPIVGGMLLSMVIIGCNYVDSEAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCHHHHHHHHHHHHCCCCCCHHHH
VIVLMAVSFFGKGIGSLGWAVVADTAPKEAIGLSGSLFNMFGNTAGIVAPIAIGYLVGAS
HHHHHHHHHHHCCHHHCCCEEEECCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCC
GSFNGALVFVGLNALVTVFSYLVIVKDIRRVELRHQAA
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNQTPSRDLPIDLARTERRTAVRYWILAMLFVVTTLNYADRATLSITGTPIRQAFGIDP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCH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CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]