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The map label for this gene is hppD [H]

Identifier: 189353858

GI number: 189353858

Start: 2164013

End: 2165905

Strand: Direct

Name: hppD [H]

Synonym: BMULJ_05110

Alternate gene names: 189353858

Gene position: 2164013-2165905 (Clockwise)

Preceding gene: 189353854

Following gene: 189353859

Centisome position: 87.5

GC content: 68.83

Gene sequence:

>1893_bases
ATGCAGCGCTCGATCGCCACCGTTTCCCTGTCCGGCACGCTCGCCGAAAAGCTCGCCGCCATTCAGGCCGCGGGCTTCGA
CGGCGTCGAAATCTTCGAGAACGATCTCGTCTACTTCGACGGATCGCCGGCCGACGTCCGGCGCATGGCGGCCGATCTCG
GCCTCGACATCGTGCTGTTCCAGCCGTTTCGCGATTTCGAGGGCGTAAGCGCCGCGCAGCTCGCGCGCAATCTCGACCGC
GTGCGCCGCAAGTTCGACGTGATGCATGCGCTCGGCACCGACCGCATTCTGGTCTGCAGCAACGTGTCGCCCGACACCAT
CGCCGACGACGCGCTGCTCGTCGACCAGCTCGGCGCGCTCGCGGAAGCCGCGCGCGAAGCGGGCGTCGTCGTCGCATACG
AGGCGCTGGCGTGGGGCCGCGTCGTGAAGCGCTACGGGCATGCGTGGCAGCTCGTGAATGCCGTGAACAGCCCGCACCTC
GGCCTCGCGCTCGACAGCTTCCACACGCTGTCGCTCGACGATTCGCCCGATGCGATCGCCGACATTCCGGGGGATCGCAT
CGCGTTCGTGCAGATCGCCGACGCGCCGAAGCTCGCGATGGACGTGCTCGAATGGAGCCGCCATTACCGCTCGTTCCCCG
GCCAGGGCGACTTCGATCTCGCGCGCTTCACCGCGCGCGTGATCGAATCGGGCTATCCGGGGCCGCTGTCGCTCGAGATC
TTCAACGACGGCTTTCGCGCGGCGCCGACCGCGATCACGGCCGCCGACGGCCATCGCTCGCTGCTGTATCTCGAAGAGCT
CACGCGTGCGCAGCTCGCCGCCGACGGCCGCGCGCCGGCGGCCGATCAGCCGCTGTTCGCGCCGCCCGCGCCGCCCGCGC
ACGTCGGATTCCAGTTCATCGAATTCGCGGTCGACGCGCAGGCGGCGGCGACCGTCGGCGACTGGCTGCGCCGGATGCGC
TTCCGGCTCGCCGGCCGCCACCGCTCGAAGGACGTCACGCTGTTTCAGCACGGCGCCGCGTCGATCGTGCTGAACGCCGA
GCGCGACTCGTTCGCCGATGCGTTCTTCCAGCAGCACGGGCTGTCGCTCTGCGCGTCGGCGTTCCGCGTCGACGATGCGA
AAGTCGCGTTCGAACGGGCGGCAGGCTTCGGATATGCGCCGTTTTCCGGCCGCGTCGGGCCGAACGAGCGCGTGTTGCCG
AGCGTGAAGGCGCCGGACGGCAGCCTCGACTATTTCGTCGACGAAGCGCCGAACGGGCCGACGCTGTACGAATCCGACTT
CGTGCTGACCGACATCGACGGCCCGACCGAAGTCGGCCCGCTGACCGGCATCGACCACGTCTGTCTCGCGCTGCCGGCCG
ACGCGCTGGATACATGGATCCTGTTCTTCAAGACCGCGTTCGGGTTCGAGGCCGAGCGCAGCTGGCTCGTGCCCGACCCG
TACGGGCTCGTGCGCAGCCGCGCGGTGCGCAGCGCGGACGGCTCCGTGCGGATCGCGCTGAACGCGTCGGTCGACCGGCA
CACGGCCGTCGCCGAATCGCTGAACCGCTACCACGGGACGGGGCTGAATCACGTCGCGTTCCGCACCGACGACATCGTGA
AGGCGATCGCGGCGTTCGCCGCCGATGGCGTGTCGTTCCTGCGCATTCCGGCCAATTACTACGACGATCTCGCGGCGCGC
TACGGATTGTCGGACGAGATGATCGACACGCTCAGCACGCACCATCTGCTCTACGACCGCGACGAACGGGGCGGCGAATT
CCTGCACGCGTATACGGAGCTGGTCGACAACCGCTTTTCGTTCGAGCTCGTCGAGCGCCGCGGCGGATACGACGGTTACG
GCGCCGCCAATGCGGCCGTGCGGCTCGCCGCGCAGGCGCAACGGCGCAAGTAG

Upstream 100 bases:

>100_bases
CCCCCAGTAAACTCGGGATATGGCGCGCGCGGCGAATTCAACGACTGGTTCATTCAGGGTCGGTTCGGGCGGCGCCGCCC
GTTCTCCGCAGGATCCGCCC

Downstream 100 bases:

>100_bases
CGCGCGGCATCGCACCGCACACCGGGCCGGCGGCGTTACATGCGGTAACGCGATGCTGGTGCGATCGCACGTCGCGCGGT
GCCGTTTTAAGAATCGCTTA

Product: 4-hydroxyphenylpyruvate dioxygenase

Products: NA

Alternate protein names: 4HPPD; HPD; HPPDase [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MQRSIATVSLSGTLAEKLAAIQAAGFDGVEIFENDLVYFDGSPADVRRMAADLGLDIVLFQPFRDFEGVSAAQLARNLDR
VRRKFDVMHALGTDRILVCSNVSPDTIADDALLVDQLGALAEAAREAGVVVAYEALAWGRVVKRYGHAWQLVNAVNSPHL
GLALDSFHTLSLDDSPDAIADIPGDRIAFVQIADAPKLAMDVLEWSRHYRSFPGQGDFDLARFTARVIESGYPGPLSLEI
FNDGFRAAPTAITAADGHRSLLYLEELTRAQLAADGRAPAADQPLFAPPAPPAHVGFQFIEFAVDAQAAATVGDWLRRMR
FRLAGRHRSKDVTLFQHGAASIVLNAERDSFADAFFQQHGLSLCASAFRVDDAKVAFERAAGFGYAPFSGRVGPNERVLP
SVKAPDGSLDYFVDEAPNGPTLYESDFVLTDIDGPTEVGPLTGIDHVCLALPADALDTWILFFKTAFGFEAERSWLVPDP
YGLVRSRAVRSADGSVRIALNASVDRHTAVAESLNRYHGTGLNHVAFRTDDIVKAIAAFAADGVSFLRIPANYYDDLAAR
YGLSDEMIDTLSTHHLLYDRDERGGEFLHAYTELVDNRFSFELVERRGGYDGYGAANAAVRLAAQAQRRK

Sequences:

>Translated_630_residues
MQRSIATVSLSGTLAEKLAAIQAAGFDGVEIFENDLVYFDGSPADVRRMAADLGLDIVLFQPFRDFEGVSAAQLARNLDR
VRRKFDVMHALGTDRILVCSNVSPDTIADDALLVDQLGALAEAAREAGVVVAYEALAWGRVVKRYGHAWQLVNAVNSPHL
GLALDSFHTLSLDDSPDAIADIPGDRIAFVQIADAPKLAMDVLEWSRHYRSFPGQGDFDLARFTARVIESGYPGPLSLEI
FNDGFRAAPTAITAADGHRSLLYLEELTRAQLAADGRAPAADQPLFAPPAPPAHVGFQFIEFAVDAQAAATVGDWLRRMR
FRLAGRHRSKDVTLFQHGAASIVLNAERDSFADAFFQQHGLSLCASAFRVDDAKVAFERAAGFGYAPFSGRVGPNERVLP
SVKAPDGSLDYFVDEAPNGPTLYESDFVLTDIDGPTEVGPLTGIDHVCLALPADALDTWILFFKTAFGFEAERSWLVPDP
YGLVRSRAVRSADGSVRIALNASVDRHTAVAESLNRYHGTGLNHVAFRTDDIVKAIAAFAADGVSFLRIPANYYDDLAAR
YGLSDEMIDTLSTHHLLYDRDERGGEFLHAYTELVDNRFSFELVERRGGYDGYGAANAAVRLAAQAQRRK
>Mature_630_residues
MQRSIATVSLSGTLAEKLAAIQAAGFDGVEIFENDLVYFDGSPADVRRMAADLGLDIVLFQPFRDFEGVSAAQLARNLDR
VRRKFDVMHALGTDRILVCSNVSPDTIADDALLVDQLGALAEAAREAGVVVAYEALAWGRVVKRYGHAWQLVNAVNSPHL
GLALDSFHTLSLDDSPDAIADIPGDRIAFVQIADAPKLAMDVLEWSRHYRSFPGQGDFDLARFTARVIESGYPGPLSLEI
FNDGFRAAPTAITAADGHRSLLYLEELTRAQLAADGRAPAADQPLFAPPAPPAHVGFQFIEFAVDAQAAATVGDWLRRMR
FRLAGRHRSKDVTLFQHGAASIVLNAERDSFADAFFQQHGLSLCASAFRVDDAKVAFERAAGFGYAPFSGRVGPNERVLP
SVKAPDGSLDYFVDEAPNGPTLYESDFVLTDIDGPTEVGPLTGIDHVCLALPADALDTWILFFKTAFGFEAERSWLVPDP
YGLVRSRAVRSADGSVRIALNASVDRHTAVAESLNRYHGTGLNHVAFRTDDIVKAIAAFAADGVSFLRIPANYYDDLAAR
YGLSDEMIDTLSTHHLLYDRDERGGEFLHAYTELVDNRFSFELVERRGGYDGYGAANAAVRLAAQAQRRK

Specific function: Unknown

COG id: COG3185

COG function: function code ER; 4-hydroxyphenylpyruvate dioxygenase and related hemolysins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

Organism=Homo sapiens, GI285002264, Length=189, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI4504477, Length=189, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17555220, Length=192, Percent_Identity=30.2083333333333, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356105, Length=190, Percent_Identity=28.9473684210526, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24667510, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.27 [H]

Molecular weight: Translated: 68598; Mature: 68598

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRSIATVSLSGTLAEKLAAIQAAGFDGVEIFENDLVYFDGSPADVRRMAADLGLDIVLF
CCCCEEEEEECHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCHHHHHHHHHCCCEEEEE
QPFRDFEGVSAAQLARNLDRVRRKFDVMHALGTDRILVCSNVSPDTIADDALLVDQLGAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHH
AEAAREAGVVVAYEALAWGRVVKRYGHAWQLVNAVNSPHLGLALDSFHTLSLDDSPDAIA
HHHHHHCCEEEEEHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCEEEEECCCCCCHHH
DIPGDRIAFVQIADAPKLAMDVLEWSRHYRSFPGQGDFDLARFTARVIESGYPGPLSLEI
CCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
FNDGFRAAPTAITAADGHRSLLYLEELTRAQLAADGRAPAADQPLFAPPAPPAHVGFQFI
ECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
EFAVDAQAAATVGDWLRRMRFRLAGRHRSKDVTLFQHGAASIVLNAERDSFADAFFQQHG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHH
LSLCASAFRVDDAKVAFERAAGFGYAPFSGRVGPNERVLPSVKAPDGSLDYFVDEAPNGP
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
TLYESDFVLTDIDGPTEVGPLTGIDHVCLALPADALDTWILFFKTAFGFEAERSWLVPDP
CEEECCEEEECCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YGLVRSRAVRSADGSVRIALNASVDRHTAVAESLNRYHGTGLNHVAFRTDDIVKAIAAFA
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHH
ADGVSFLRIPANYYDDLAARYGLSDEMIDTLSTHHLLYDRDERGGEFLHAYTELVDNRFS
HCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCH
FELVERRGGYDGYGAANAAVRLAAQAQRRK
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQRSIATVSLSGTLAEKLAAIQAAGFDGVEIFENDLVYFDGSPADVRRMAADLGLDIVLF
CCCCEEEEEECHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCHHHHHHHHHCCCEEEEE
QPFRDFEGVSAAQLARNLDRVRRKFDVMHALGTDRILVCSNVSPDTIADDALLVDQLGAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHH
AEAAREAGVVVAYEALAWGRVVKRYGHAWQLVNAVNSPHLGLALDSFHTLSLDDSPDAIA
HHHHHHCCEEEEEHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCEEEEECCCCCCHHH
DIPGDRIAFVQIADAPKLAMDVLEWSRHYRSFPGQGDFDLARFTARVIESGYPGPLSLEI
CCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
FNDGFRAAPTAITAADGHRSLLYLEELTRAQLAADGRAPAADQPLFAPPAPPAHVGFQFI
ECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
EFAVDAQAAATVGDWLRRMRFRLAGRHRSKDVTLFQHGAASIVLNAERDSFADAFFQQHG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHH
LSLCASAFRVDDAKVAFERAAGFGYAPFSGRVGPNERVLPSVKAPDGSLDYFVDEAPNGP
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
TLYESDFVLTDIDGPTEVGPLTGIDHVCLALPADALDTWILFFKTAFGFEAERSWLVPDP
CEEECCEEEECCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YGLVRSRAVRSADGSVRIALNASVDRHTAVAESLNRYHGTGLNHVAFRTDDIVKAIAAFA
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHH
ADGVSFLRIPANYYDDLAARYGLSDEMIDTLSTHHLLYDRDERGGEFLHAYTELVDNRFS
HCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCH
FELVERRGGYDGYGAANAAVRLAAQAQRRK
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1572351; 10467142 [H]