Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 189353823

GI number: 189353823

Start: 2125141

End: 2125899

Strand: Reverse

Name: glpR [H]

Synonym: BMULJ_05070

Alternate gene names: 189353823

Gene position: 2125899-2125141 (Counterclockwise)

Preceding gene: 189353827

Following gene: 189353822

Centisome position: 85.96

GC content: 71.54

Gene sequence:

>759_bases
ATGCTCGCGGAACAACGTCATCAGTACATCCTGTCGGAACTCGGTCGATCGGGCGCGCTGTCGGTCGCGGAACTCGTGCG
CTCGCTCGACGTGTCGCGCGAGACCGTGCGGCGCGATCTGAACGCGCTCGCCGCGCGCGGCTTGCTCGTGATGACGCACG
GCGGCGCGCTGGCGGCCGACCGGCGCGAGCCGAGCCTCTCTGAGCGCGAGGCCGCGAACGCCGACGCCAAGCGGGCGATC
GGCCGGCGTGCGGCCGAGTTCGTGCCGGACGGCGCATCGGTGCTGATCGATTCCGGCAGTACGCCGCACGCGGTCGCGCT
CGCGCTCGCCGACCGGCATCGGCTGTCGGTCTACACGAACGACTGGCGCACCGCGCTCGTGCTCGCGCGGCGCAACGGCA
ATCGCGTGACGCTGCTCGGCGGCGAGCTGTCCGACGACGAGGACGCGACGTTCGGCCTCGACACGATCCAGCAGCTTGCG
CAATACCACGTCGATTTCGCGTTCGTCGGCGCGGGCGGCATCACGGCCGACGGCGACTGCACCGACTACTCGCGGCTCGC
GGCCGAGGTGCGCAGCCGGATGATCGCGGCCGCCGGCACCGCGATCATCGTCGCCGATCATTCGAAGTTCGGCCGCGTGA
CGCCGGTGCGCATCAACGGCACGTCGGCCGCGCGCTATCTGGTGACCGAACGCGCGCCCGAGCGCGCCGTACGTCGCGCG
CTGACCGCACGCGGCATCGAACTCGTGCTCTGCGGCTGA

Upstream 100 bases:

>100_bases
ATGCCCGTCGCGGCCGGCGTGGCGCCGTCAAATCGCAGTCAAACGGCCGTAATACAATGGCCGGCCATCCCATTACCTGT
CGCCTCGGGCGCAACGCGCG

Downstream 100 bases:

>100_bases
CGCGCGCGCGACACATAAGCTTCATCGAACCGTCATCCCGACGGAAACATCGACACGGACACTCGACACCGGTTCTCGCC
GATTGCGTGCGGCCCCTGCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLAEQRHQYILSELGRSGALSVAELVRSLDVSRETVRRDLNALAARGLLVMTHGGALAADRREPSLSEREAANADAKRAI
GRRAAEFVPDGASVLIDSGSTPHAVALALADRHRLSVYTNDWRTALVLARRNGNRVTLLGGELSDDEDATFGLDTIQQLA
QYHVDFAFVGAGGITADGDCTDYSRLAAEVRSRMIAAAGTAIIVADHSKFGRVTPVRINGTSAARYLVTERAPERAVRRA
LTARGIELVLCG

Sequences:

>Translated_252_residues
MLAEQRHQYILSELGRSGALSVAELVRSLDVSRETVRRDLNALAARGLLVMTHGGALAADRREPSLSEREAANADAKRAI
GRRAAEFVPDGASVLIDSGSTPHAVALALADRHRLSVYTNDWRTALVLARRNGNRVTLLGGELSDDEDATFGLDTIQQLA
QYHVDFAFVGAGGITADGDCTDYSRLAAEVRSRMIAAAGTAIIVADHSKFGRVTPVRINGTSAARYLVTERAPERAVRRA
LTARGIELVLCG
>Mature_252_residues
MLAEQRHQYILSELGRSGALSVAELVRSLDVSRETVRRDLNALAARGLLVMTHGGALAADRREPSLSEREAANADAKRAI
GRRAAEFVPDGASVLIDSGSTPHAVALALADRHRLSVYTNDWRTALVLARRNGNRVTLLGGELSDDEDATFGLDTIQQLA
QYHVDFAFVGAGGITADGDCTDYSRLAAEVRSRMIAAAGTAIIVADHSKFGRVTPVRINGTSAARYLVTERAPERAVRRA
LTARGIELVLCG

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=34.1269841269841, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=30.8943089430894, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=28.740157480315, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=28.1746031746032, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=29.6610169491525, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI226510968, Length=252, Percent_Identity=28.1746031746032, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787063, Length=245, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=25.7936507936508, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789170, Length=240, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787540, Length=209, Percent_Identity=29.1866028708134, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790753, Length=250, Percent_Identity=24.8, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27001; Mature: 27001

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEQRHQYILSELGRSGALSVAELVRSLDVSRETVRRDLNALAARGLLVMTHGGALAAD
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCEECC
RREPSLSEREAANADAKRAIGRRAAEFVPDGASVLIDSGSTPHAVALALADRHRLSVYTN
CCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCEEEEEEC
DWRTALVLARRNGNRVTLLGGELSDDEDATFGLDTIQQLAQYHVDFAFVGAGGITADGDC
CCEEEEEEEECCCCEEEEECCCCCCCCCCEECHHHHHHHHHHCCCEEEEECCCCCCCCCC
TDYSRLAAEVRSRMIAAAGTAIIVADHSKFGRVTPVRINGTSAARYLVTERAPERAVRRA
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHH
LTARGIELVLCG
HHHCCEEEEEEC
>Mature Secondary Structure
MLAEQRHQYILSELGRSGALSVAELVRSLDVSRETVRRDLNALAARGLLVMTHGGALAAD
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCEECC
RREPSLSEREAANADAKRAIGRRAAEFVPDGASVLIDSGSTPHAVALALADRHRLSVYTN
CCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCEEEEEEC
DWRTALVLARRNGNRVTLLGGELSDDEDATFGLDTIQQLAQYHVDFAFVGAGGITADGDC
CCEEEEEEEECCCCEEEEECCCCCCCCCCEECHHHHHHHHHHCCCEEEEECCCCCCCCCC
TDYSRLAAEVRSRMIAAAGTAIIVADHSKFGRVTPVRINGTSAARYLVTERAPERAVRRA
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHH
LTARGIELVLCG
HHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]