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The map label for this gene is sdaA [H]

Identifier: 189353767

GI number: 189353767

Start: 2047757

End: 2049142

Strand: Reverse

Name: sdaA [H]

Synonym: BMULJ_05014

Alternate gene names: 189353767

Gene position: 2049142-2047757 (Counterclockwise)

Preceding gene: 189353776

Following gene: 189353766

Centisome position: 82.86

GC content: 66.96

Gene sequence:

>1386_bases
ATGAACGTCAGCGTTTTCGACCTGTTCAAGATCGGCATCGGACCGTCCAGCTCGCATACGGTCGGACCGATGATCGCGGC
GTGCCGCTTCGCGTCGCACGTGGAGGACGCGAACCTGCTCGGCTTCGTGCGCCGCGTGCGCGTCGAGCTGTACGGCTCGC
TCGGCGCGACGGGCAAGGGCCACGGCACCGACAAGGCCGTGCTGCTCGGCCTCGAGGGCCATCTGCCGGACACGATCGAT
CCGGATCTGATCGAGCCGCGCCTCGCCGCGATCCGCGCCGAGAAGTCGCTGTCGCTGCTCGGCAAGCAGACGATCCGCTT
CGACGAGAAGGAGCACATCGGCTTCTACCGGAAGCTGATGACGGGCACGAGCATCGTGCACCCGAACGGCATGCGCTTCC
AGGCGTTCGACGAACACGGTCAGCTGCTCGTCGAGAAGGAGTATTACTCGATCGGCGGCGGTTTCGTCGTGAACCGCGAC
GGCGATCGCGTCAACGGCGTGCGCGCGGCGGCCGAGGTGCCGTATCCGTTTCGCACCGGCGACGACCTGATGCGCCAGTG
CCGCGAGCACGGGCTGTCGATCGCCGAGCTGATGATGCGCAACGAATGCGCGCTGCGTCCGGAAGACGAAGTGCGTGCGG
GGCTGCTCGCGATCTGGCGCACGATGGCGGCCTGCGTCGAGCGCGGCTGCAAGGTCGAGGGCGATCTGCCGGGCCCGATG
CGCGTCAAGCGCCGCGCGGCCGAACTGAATGCGCGGCTGCGTGCGCGTTCCGAGGAATCGCTGCGCGATCCGTTGTCGAT
GCTCGACTGGGTCAACCTCTATGCGATGGCCGTCAACGAGGAGAACGCGGCGGGCGGGCGCGTCGTCACCGCGCCGACCA
ACGGCGCGGCAGGCGTGATTCCGGCCGTGCTGCACTACTACGTGAAGTTCGTGCCGGGCTCGAACGAGGCAGGCATCGTC
GAATTCCTGCTGACCGCCGCGGCGATCGGAATCATCTACAAGGAAACCGCGTCGATCTCCGGCGCGGAAGTCGGTTGCCA
GGGCGAAGTCGGCGTCGCGTGCTCGATGGCCGCGGCCGCGCACGCGGCCGTGATGGGCGGCACGCCGGACCAGGTCGAGA
ACGCCGCCGAAATCGGCATGGAGCACAACCTCGGGATGACCTGCGACCCGGTCGGCGGGCTCGTGCAGATCCCGTGCATC
GAGCGCAACGCGATGGGCGCGATCAAGGCGCTGAACGCATCGCGCATGGCGCTGAAGGGCAACGGTCAGCACTACGTGTC
GCTCGATTCCGTCATCAAGACGATGCGCGAGACGGGCGCCGACATGAAGACGAAATACAAGGAAACGTCGCGCGGCGGTC
TGGCCGTGAACGTCATCGAATGCTAA

Upstream 100 bases:

>100_bases
GCTATCCCACGCCGATGCCGTTTTTGTTCTATCGGCGGATTTTACGCTTTGATGTACTGGCGTCCAACGTCACTTTGCAG
TGCCATCCAGAGGAAGCCAG

Downstream 100 bases:

>100_bases
CGAAGGACCATCAACATGAGCCGCTACTCGATATTCAGCCTGTTCCGCAACGGCCTCTCGTATCACGAGAACTGGGAGAA
GCAATGGAAGAGCCCCGAGC

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRVELYGSLGATGKGHGTDKAVLLGLEGHLPDTID
PDLIEPRLAAIRAEKSLSLLGKQTIRFDEKEHIGFYRKLMTGTSIVHPNGMRFQAFDEHGQLLVEKEYYSIGGGFVVNRD
GDRVNGVRAAAEVPYPFRTGDDLMRQCREHGLSIAELMMRNECALRPEDEVRAGLLAIWRTMAACVERGCKVEGDLPGPM
RVKRRAAELNARLRARSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEAGIV
EFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAAHAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCI
ERNAMGAIKALNASRMALKGNGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC

Sequences:

>Translated_461_residues
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRVELYGSLGATGKGHGTDKAVLLGLEGHLPDTID
PDLIEPRLAAIRAEKSLSLLGKQTIRFDEKEHIGFYRKLMTGTSIVHPNGMRFQAFDEHGQLLVEKEYYSIGGGFVVNRD
GDRVNGVRAAAEVPYPFRTGDDLMRQCREHGLSIAELMMRNECALRPEDEVRAGLLAIWRTMAACVERGCKVEGDLPGPM
RVKRRAAELNARLRARSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEAGIV
EFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAAHAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCI
ERNAMGAIKALNASRMALKGNGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC
>Mature_461_residues
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRVELYGSLGATGKGHGTDKAVLLGLEGHLPDTID
PDLIEPRLAAIRAEKSLSLLGKQTIRFDEKEHIGFYRKLMTGTSIVHPNGMRFQAFDEHGQLLVEKEYYSIGGGFVVNRD
GDRVNGVRAAAEVPYPFRTGDDLMRQCREHGLSIAELMMRNECALRPEDEVRAGLLAIWRTMAACVERGCKVEGDLPGPM
RVKRRAAELNARLRARSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEAGIV
EFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAAHAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCI
ERNAMGAIKALNASRMALKGNGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=462, Percent_Identity=52.3809523809524, Blast_Score=470, Evalue=1e-134,
Organism=Escherichia coli, GI1788116, Length=460, Percent_Identity=51.304347826087, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI48994925, Length=458, Percent_Identity=51.9650655021834, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49527; Mature: 49527

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRVELYGSLGATGKG
CCCEEEEHEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
HGTDKAVLLGLEGHLPDTIDPDLIEPRLAAIRAEKSLSLLGKQTIRFDEKEHIGFYRKLM
CCCCCEEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TGTSIVHPNGMRFQAFDEHGQLLVEKEYYSIGGGFVVNRDGDRVNGVRAAAEVPYPFRTG
CCCCEECCCCCEEEEECCCCCEEEEEEEEECCCCEEEECCCCCCCCEEHHHCCCCCCCCC
DDLMRQCREHGLSIAELMMRNECALRPEDEVRAGLLAIWRTMAACVERGCKVEGDLPGPM
HHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHH
RVKRRAAELNARLRARSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCHHH
PAVLHYYVKFVPGSNEAGIVEFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAA
HHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHECCCCCCCCCCCCCCCCCHHHHHHHHH
HAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRMALKG
HHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCEECCCHHHHHHHCCCCEEEEEC
NGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC
CCCEEEEHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDANLLGFVRRVRVELYGSLGATGKG
CCCEEEEHEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
HGTDKAVLLGLEGHLPDTIDPDLIEPRLAAIRAEKSLSLLGKQTIRFDEKEHIGFYRKLM
CCCCCEEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TGTSIVHPNGMRFQAFDEHGQLLVEKEYYSIGGGFVVNRDGDRVNGVRAAAEVPYPFRTG
CCCCEECCCCCEEEEECCCCCEEEEEEEEECCCCEEEECCCCCCCCEEHHHCCCCCCCCC
DDLMRQCREHGLSIAELMMRNECALRPEDEVRAGLLAIWRTMAACVERGCKVEGDLPGPM
HHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHH
RVKRRAAELNARLRARSEESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCHHH
PAVLHYYVKFVPGSNEAGIVEFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAA
HHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHECCCCCCCCCCCCCCCCCHHHHHHHHH
HAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRMALKG
HHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCEECCCHHHHHHHCCCCEEEEEC
NGQHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNVIEC
CCCEEEEHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]