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The map label for this gene is soxB [H]

Identifier: 189353766

GI number: 189353766

Start: 2046497

End: 2047741

Strand: Reverse

Name: soxB [H]

Synonym: BMULJ_05013

Alternate gene names: 189353766

Gene position: 2047741-2046497 (Counterclockwise)

Preceding gene: 189353767

Following gene: 189353765

Centisome position: 82.8

GC content: 65.7

Gene sequence:

>1245_bases
ATGAGCCGCTACTCGATATTCAGCCTGTTCCGCAACGGCCTCTCGTATCACGAGAACTGGGAGAAGCAATGGAAGAGCCC
CGAGCCCAAGCGTGAGTACGACGTCGTGATCGTCGGCGGCGGCGGGCACGGGCTCGCGACCGCGTACTACCTCGCGAAGG
AGCACGGGATCACGAACGTCGCGATTCTCGAGAAAGGCTGGATCGGCGGCGGCAACACCGCGCGCAACACGACGATCGTG
CGCTCGAACTATCTGTGGGACGAATCGGCCGCGCTGTACGAGAAGGCGATGAAGCTCTGGGAAGGGCTGTCGCAGGATCT
CAACTACAACGTGATGTTCAGCCAGCGCGGCGTGATGAACCTCGCGCACACGCTGCAGGACGTGCGCGACACCGAGCGCC
GCGTGAACGCGAACCGGCTCAACGGCGTCGACGCGGAATTCCTGACGCCCGCGCAGGTGAAGGAAATCGAACCGACGATC
AATCTGAACAGTCGCTATCCGGTGCTCGGCGCATCGATCCAGCGTCGCGCGGGCGTCGCGCGTCACGACGCCGTCGCATG
GGGCTTCGCGCGCGGCGCGGACCGCGCGGGCGTCGACATCATCCAGAACTGCCAGGTCACCGGCATTCGTCGCGAAGGCG
GCGCGGTGGTCGGCGTCGATACCGTGAAGGGCTTCATCAAGGCGAAGAAGGTCGCGGTGGTCGCGGCCGGCAACACGACG
ACGCTCGCCGACATGGCCGGCGTGCGGCTGCCGATCGAAAGCCATCCGCTGCAGGCGCTCGTGTCCGAGCCGATCAAGCC
CGTCGTCAACTCGGTGATCATGTCGAACGCCGTGCACGCGTACATCAGTCAGTCCGACAAGGGCGACCTCGTGATCGGCG
CGGGCATCGACCAATACACGGGCTTCGGCCAGCGCGGCAGCTTCCACATCATCGAAGGCACGCTGCAGGCGATCGTCGAA
ATGTTCCCGGTGTTCTCGCGCGTGCGCATGAACCGTCAGTGGGGCGGCATCGTCGACGTGTCGCCGGACGCCTGCCCGAT
CATCAGCAAGACCGACGTGAAGGGGCTGTACTTCAACTGCGGCTGGGGGACGGGCGGCTTCAAGGCGACGCCGGGCTCGG
GCTGGGTGTTCGCCCATACGATCGCTCGCGACGAACCGCATCCGCTGAACGCGCCGTTCTCGCTCGACCGCTTCTACACC
GGCCACCTGATCGACGAACACGGCGCCGCCGCCGTCGCGCACTGA

Upstream 100 bases:

>100_bases
GATGCGCGAGACGGGCGCCGACATGAAGACGAAATACAAGGAAACGTCGCGCGGCGGTCTGGCCGTGAACGTCATCGAAT
GCTAACGAAGGACCATCAAC

Downstream 100 bases:

>100_bases
ACGAGGAGAAACCAACATGTTGCTGATCGAATGTCCGTGGTGCGGGCCGCGCGCCGAATCCGAGTTCACGTGCGGCGGCG
AAGCCGACATCGTGCGCCCG

Product: sarcosine oxidase beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNVAILEKGWIGGGNTARNTTIV
RSNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQVKEIEPTI
NLNSRYPVLGASIQRRAGVARHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTT
TLADMAGVRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFHIIEGTLQAIVE
MFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFSLDRFYT
GHLIDEHGAAAVAH

Sequences:

>Translated_414_residues
MSRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNVAILEKGWIGGGNTARNTTIV
RSNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQVKEIEPTI
NLNSRYPVLGASIQRRAGVARHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTT
TLADMAGVRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFHIIEGTLQAIVE
MFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFSLDRFYT
GHLIDEHGAAAVAH
>Mature_413_residues
SRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNVAILEKGWIGGGNTARNTTIVR
SNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQVKEIEPTIN
LNSRYPVLGASIQRRAGVARHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTTT
LADMAGVRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFHIIEGTLQAIVEM
FPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFSLDRFYTG
HLIDEHGAAAVAH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=394, Percent_Identity=24.3654822335025, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI21361378, Length=394, Percent_Identity=24.3654822335025, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI24797151, Length=397, Percent_Identity=22.9219143576826, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI194306651, Length=382, Percent_Identity=23.2984293193717, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787438, Length=330, Percent_Identity=23.6363636363636, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20130091, Length=383, Percent_Identity=23.4986945169713, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45192; Mature: 45061

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNV
CCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEE
AILEKGWIGGGNTARNTTIVRSNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMN
EEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
LAHTLQDVRDTERRVNANRLNGVDAEFLTPAQVKEIEPTINLNSRYPVLGASIQRRAGVA
HHHHHHHHHHHHHHCCHHHCCCCCCHHCCCHHHHHCCCCEECCCCCCCCCCHHHHHCCCC
RHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTT
HHHHHHHHHHCCCCCCCCHHHCCCEEEEEEECCCEEEEHHHHHHHHEEEEEEEEECCCCE
TLADMAGVRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYT
EHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHC
GFGQRGSFHIIEGTLQAIVEMFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNC
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCEEEEEC
GWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFSLDRFYTGHLIDEHGAAAVAH
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCEECCCCCEECCC
>Mature Secondary Structure 
SRYSIFSLFRNGLSYHENWEKQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNV
CCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEE
AILEKGWIGGGNTARNTTIVRSNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMN
EEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
LAHTLQDVRDTERRVNANRLNGVDAEFLTPAQVKEIEPTINLNSRYPVLGASIQRRAGVA
HHHHHHHHHHHHHHCCHHHCCCCCCHHCCCHHHHHCCCCEECCCCCCCCCCHHHHHCCCC
RHDAVAWGFARGADRAGVDIIQNCQVTGIRREGGAVVGVDTVKGFIKAKKVAVVAAGNTT
HHHHHHHHHHCCCCCCCCHHHCCCEEEEEEECCCEEEEHHHHHHHHEEEEEEEEECCCCE
TLADMAGVRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYT
EHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHC
GFGQRGSFHIIEGTLQAIVEMFPVFSRVRMNRQWGGIVDVSPDACPIISKTDVKGLYFNC
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCEEEEEC
GWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFSLDRFYTGHLIDEHGAAAVAH
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]