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The map label for this gene is csgA [H]

Identifier: 189353743

GI number: 189353743

Start: 2014278

End: 2014991

Strand: Reverse

Name: csgA [H]

Synonym: BMULJ_04988

Alternate gene names: 189353743

Gene position: 2014991-2014278 (Counterclockwise)

Preceding gene: 189353745

Following gene: 189353740

Centisome position: 81.47

GC content: 69.19

Gene sequence:

>714_bases
ATGCCCGATACCTCTGACCCTCGTCCCACGATCCTGCTCGTCGGCGCATCGCGCGGCCTCGGTCACGCAATGGCGGCCGA
GTTCCTGAAGCGCGGCTGGGACGTCGTGGGCACCGTGCGCGCGGATCGCGGACGCACGCCGCTGCACGCGCTCGCCGAGG
CGTACCCGGACCGGCTGCGGATCGAAACACTCGATATCACGCAGCCCGAGCAGATCCGCGCACTGGCCGCGCGCCTGTCC
GGACGCGTGTTCGACATCCTGTTCGTCAATGCCGGGACGACGAATCCCGATCCGACGCAGACGATCGGCGAGGTGTCGAC
CGACGATTTCGTCGACCTGATGATCACGAACGCACTGAGCCCGATGCGCGTGGTCGAGACGCTGGCCGGCCTCGTGCCGC
GCGACGGGCTGATCGGCATCATGTCGTCGGGGCAGGGCAGCATCGCCGACAACGAATCGGGCCAGCGCGAGCTCTATCGC
GGCAGCAAGGCCGCGCTGAACCAGTTCATGCGCAGCTTCGCGGCGCGTCACGCGCAGACGCCGCTCGCGATGGTGCTGAT
CGCGCCCGGCTGGGTGCGCACGGAGCTCGGCGGGCCGGATGCGCGGCTGTCGATCGACGAAAGCGTGCCGGGCGTCGTCG
ATGTGCTGCTCGCCAAGCGCGGCCGCGCGGGGCTCGAATATCTCGACTATCGCGGTCGAACCGTGCGGTGGTGA

Upstream 100 bases:

>100_bases
GATGGCGTCCGATGCAATCGACGATTGCATGCGGCGCGTCTGGTGCAAACCGGACGCGATCCCGACAATGCATGGTGCCG
CTGTCGAAAAGGAGAAGCCC

Downstream 100 bases:

>100_bases
GCGGCACGGTTTGCGCAACGCGGGTCGGGCACGCGTCGTCCGCAGCGACTGCGCTGCCCGTCATGCAGCTGTCGTGCACG
GCCCCGCGATCGACGCCGTG

Product: putative short-chain alcohol dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: C signal [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MPDTSDPRPTILLVGASRGLGHAMAAEFLKRGWDVVGTVRADRGRTPLHALAEAYPDRLRIETLDITQPEQIRALAARLS
GRVFDILFVNAGTTNPDPTQTIGEVSTDDFVDLMITNALSPMRVVETLAGLVPRDGLIGIMSSGQGSIADNESGQRELYR
GSKAALNQFMRSFAARHAQTPLAMVLIAPGWVRTELGGPDARLSIDESVPGVVDVLLAKRGRAGLEYLDYRGRTVRW

Sequences:

>Translated_237_residues
MPDTSDPRPTILLVGASRGLGHAMAAEFLKRGWDVVGTVRADRGRTPLHALAEAYPDRLRIETLDITQPEQIRALAARLS
GRVFDILFVNAGTTNPDPTQTIGEVSTDDFVDLMITNALSPMRVVETLAGLVPRDGLIGIMSSGQGSIADNESGQRELYR
GSKAALNQFMRSFAARHAQTPLAMVLIAPGWVRTELGGPDARLSIDESVPGVVDVLLAKRGRAGLEYLDYRGRTVRW
>Mature_236_residues
PDTSDPRPTILLVGASRGLGHAMAAEFLKRGWDVVGTVRADRGRTPLHALAEAYPDRLRIETLDITQPEQIRALAARLSG
RVFDILFVNAGTTNPDPTQTIGEVSTDDFVDLMITNALSPMRVVETLAGLVPRDGLIGIMSSGQGSIADNESGQRELYRG
SKAALNQFMRSFAARHAQTPLAMVLIAPGWVRTELGGPDARLSIDESVPGVVDVLLAKRGRAGLEYLDYRGRTVRW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17559962, Length=231, Percent_Identity=29.004329004329, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17558994, Length=226, Percent_Identity=27.8761061946903, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559964, Length=228, Percent_Identity=26.7543859649123, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193207563, Length=226, Percent_Identity=26.1061946902655, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17558992, Length=226, Percent_Identity=27.4336283185841, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17558996, Length=223, Percent_Identity=27.8026905829596, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI72001658, Length=234, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532177, Length=264, Percent_Identity=26.8939393939394, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17541382, Length=228, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=28.2828282828283, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640547, Length=251, Percent_Identity=26.6932270916335, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25703; Mature: 25572

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTSDPRPTILLVGASRGLGHAMAAEFLKRGWDVVGTVRADRGRTPLHALAEAYPDRLR
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCEE
IETLDITQPEQIRALAARLSGRVFDILFVNAGTTNPDPTQTIGEVSTDDFVDLMITNALS
EEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHCCC
PMRVVETLAGLVPRDGLIGIMSSGQGSIADNESGQRELYRGSKAALNQFMRSFAARHAQT
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCC
PLAMVLIAPGWVRTELGGPDARLSIDESVPGVVDVLLAKRGRAGLEYLDYRGRTVRW
CEEEEEECCCEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
PDTSDPRPTILLVGASRGLGHAMAAEFLKRGWDVVGTVRADRGRTPLHALAEAYPDRLR
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCEE
IETLDITQPEQIRALAARLSGRVFDILFVNAGTTNPDPTQTIGEVSTDDFVDLMITNALS
EEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHCCC
PMRVVETLAGLVPRDGLIGIMSSGQGSIADNESGQRELYRGSKAALNQFMRSFAARHAQT
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCC
PLAMVLIAPGWVRTELGGPDARLSIDESVPGVVDVLLAKRGRAGLEYLDYRGRTVRW
CEEEEEECCCEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]