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The map label for this gene is fixB [H]

Identifier: 189353721

GI number: 189353721

Start: 1987032

End: 1988201

Strand: Reverse

Name: fixB [H]

Synonym: BMULJ_04966

Alternate gene names: 189353721

Gene position: 1988201-1987032 (Counterclockwise)

Preceding gene: 189353722

Following gene: 189353720

Centisome position: 80.39

GC content: 70.94

Gene sequence:

>1170_bases
ATGAACAAGATCAAACGAATCGATCCGCGCCGGCCGTTCATCATCACGGCCGCCGGCCTGAAACGCATCACGCTCGGCGA
GGAAGGCAGCGCGGACGCGAGCGCCGCGCAATGGCCGGCCCACGGGCATGCGGCCGCCGCCGCGAAGCCGCGCCGCGCGG
TGCAGGACCCGAAGCACGTGATGCTCGTGGTCGCGCATGCCGAACGCGGCTCGCTCGACGACCTGTCGCGCCAGGCGATC
GCCGCGGCCGCGCTGCTCGCCGACGCGCAGACAGAAGTCGCGCTGCTCGCCTTCGGCGAACTGAAGGACGACATCGCCGA
GCTCGGCGTCGACAAGCTCGTCGAACTCGCGGGCTTCGATCGCCGCGCGTTCGCGCCCGAGAGCGAACTGCAGGCGCTGC
AGGCCTGCGTCGCCGCGCTGGCGCCGAAACACGTGTTCGTGCCCGACAACGCGACGGGCGACGGCGATCTCGGCCGCCGC
TATGCCGCGGTGGCAGGCGCAAGCGTCGCGACGAACGTCATCGAGATCGATGCGAAGCACGTCGGCACCTACGTGCATGC
GAAGCGCGCGTTCGCGACGCGTGCGCTGCCCGACGTGATCCTGCTCGCGCCGAACGCGGTCGAAGCGAAGCTGCCGTTCG
TCGGCGCGGGCGAGCGGCTGGCCGCCGATTTCATCCGGCCGGCCGCCGACGCCGCACAGCCGTATCGCGATCTCGGCCTC
GAGGAAATCGACGCCGCGCAGGTCGCGCTCGAGGAAGCGGACTTCATCGTATCGGCCGGCAACGGCGTGACCGACATCGC
CGCATTCGAGCGGCTGGCCGGCGCGTTCGGCGCGGCGATCGGCGCGAGCCGCGTCGCGGTCGACAACGGCCACTTCACGC
GCGACAAGCAGGTCGGCGCGACCGGCAAGACGGTCGAAGCGAGCGTCTATATCGCGTTCGGGATCTCGGGCGCGGTGCAG
CACCTGCAGGGCATCAAGGATTGCCGCCACGTGATCGCGGTCAACCTCGACGGCAGCGCGCCGATCGCGAAGCGCGCGAA
CCTGACGGTGGTCGGCGACGCGCAGGCGACGATCGCCGCGCTGATCGAACAGGTGCAGGCCGCGCGTGCCGCGCGCGGAC
AATCGCCGACCGCGGTCGGCGCCCGTGAACCGGAAGGAGTCGCAGCATGA

Upstream 100 bases:

>100_bases
GCGTGCCCGAACTGCACGGCGATGCTCGAAGGTGTCGTGGGCCCGCGCCCCGACGTGCTCGACGTGGCCGAACTCGTCGC
TGCCTCGCTGGAGTGAATCG

Downstream 100 bases:

>100_bases
ACGCCCCTCGCCAGTTGCAACGCATCGCGGTGCTCGTGTCCGTCGGCCGGCATCCGGTCAGCGGGACCGCGCGCTATAGC
CGCAACGATGCGGCCGCGCT

Product: electron transfer flavoprotein alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNKIKRIDPRRPFIITAAGLKRITLGEEGSADASAAQWPAHGHAAAAAKPRRAVQDPKHVMLVVAHAERGSLDDLSRQAI
AAAALLADAQTEVALLAFGELKDDIAELGVDKLVELAGFDRRAFAPESELQALQACVAALAPKHVFVPDNATGDGDLGRR
YAAVAGASVATNVIEIDAKHVGTYVHAKRAFATRALPDVILLAPNAVEAKLPFVGAGERLAADFIRPAADAAQPYRDLGL
EEIDAAQVALEEADFIVSAGNGVTDIAAFERLAGAFGAAIGASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISGAVQ
HLQGIKDCRHVIAVNLDGSAPIAKRANLTVVGDAQATIAALIEQVQAARAARGQSPTAVGAREPEGVAA

Sequences:

>Translated_389_residues
MNKIKRIDPRRPFIITAAGLKRITLGEEGSADASAAQWPAHGHAAAAAKPRRAVQDPKHVMLVVAHAERGSLDDLSRQAI
AAAALLADAQTEVALLAFGELKDDIAELGVDKLVELAGFDRRAFAPESELQALQACVAALAPKHVFVPDNATGDGDLGRR
YAAVAGASVATNVIEIDAKHVGTYVHAKRAFATRALPDVILLAPNAVEAKLPFVGAGERLAADFIRPAADAAQPYRDLGL
EEIDAAQVALEEADFIVSAGNGVTDIAAFERLAGAFGAAIGASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISGAVQ
HLQGIKDCRHVIAVNLDGSAPIAKRANLTVVGDAQATIAALIEQVQAARAARGQSPTAVGAREPEGVAA
>Mature_389_residues
MNKIKRIDPRRPFIITAAGLKRITLGEEGSADASAAQWPAHGHAAAAAKPRRAVQDPKHVMLVVAHAERGSLDDLSRQAI
AAAALLADAQTEVALLAFGELKDDIAELGVDKLVELAGFDRRAFAPESELQALQACVAALAPKHVFVPDNATGDGDLGRR
YAAVAGASVATNVIEIDAKHVGTYVHAKRAFATRALPDVILLAPNAVEAKLPFVGAGERLAADFIRPAADAAQPYRDLGL
EEIDAAQVALEEADFIVSAGNGVTDIAAFERLAGAFGAAIGASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISGAVQ
HLQGIKDCRHVIAVNLDGSAPIAKRANLTVVGDAQATIAALIEQVQAARAARGQSPTAVGAREPEGVAA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=117, Percent_Identity=43.5897435897436, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4503607, Length=117, Percent_Identity=43.5897435897436, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1787990, Length=125, Percent_Identity=32, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786226, Length=118, Percent_Identity=34.7457627118644, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=131, Percent_Identity=41.9847328244275, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325261, Length=120, Percent_Identity=41.6666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136898, Length=131, Percent_Identity=43.5114503816794, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24652801, Length=131, Percent_Identity=43.5114503816794, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 40255; Mature: 40255

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIKRIDPRRPFIITAAGLKRITLGEEGSADASAAQWPAHGHAAAAAKPRRAVQDPKHV
CCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHCCCCEE
MLVVAHAERGSLDDLSRQAIAAAALLADAQTEVALLAFGELKDDIAELGVDKLVELAGFD
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCHHHHHHHHCCC
RRAFAPESELQALQACVAALAPKHVFVPDNATGDGDLGRRYAAVAGASVATNVIEIDAKH
CCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCHHHHHEEEECHHH
VGTYVHAKRAFATRALPDVILLAPNAVEAKLPFVGAGERLAADFIRPAADAAQPYRDLGL
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCH
EEIDAAQVALEEADFIVSAGNGVTDIAAFERLAGAFGAAIGASRVAVDNGHFTRDKQVGA
HHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
TGKTVEASVYIAFGISGAVQHLQGIKDCRHVIAVNLDGSAPIAKRANLTVVGDAQATIAA
CCCEEEEEEEEEECCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEECCHHHHHH
LIEQVQAARAARGQSPTAVGAREPEGVAA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKIKRIDPRRPFIITAAGLKRITLGEEGSADASAAQWPAHGHAAAAAKPRRAVQDPKHV
CCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHCCCCEE
MLVVAHAERGSLDDLSRQAIAAAALLADAQTEVALLAFGELKDDIAELGVDKLVELAGFD
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCHHHHHHHHCCC
RRAFAPESELQALQACVAALAPKHVFVPDNATGDGDLGRRYAAVAGASVATNVIEIDAKH
CCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCHHHHHEEEECHHH
VGTYVHAKRAFATRALPDVILLAPNAVEAKLPFVGAGERLAADFIRPAADAAQPYRDLGL
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCH
EEIDAAQVALEEADFIVSAGNGVTDIAAFERLAGAFGAAIGASRVAVDNGHFTRDKQVGA
HHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
TGKTVEASVYIAFGISGAVQHLQGIKDCRHVIAVNLDGSAPIAKRANLTVVGDAQATIAA
CCCEEEEEEEEEECCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEECCHHHHHH
LIEQVQAARAARGQSPTAVGAREPEGVAA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]