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The map label for this gene is livM [H]

Identifier: 189353647

GI number: 189353647

Start: 1906431

End: 1907702

Strand: Reverse

Name: livM [H]

Synonym: BMULJ_04892

Alternate gene names: 189353647

Gene position: 1907702-1906431 (Counterclockwise)

Preceding gene: 189353648

Following gene: 189353646

Centisome position: 77.14

GC content: 66.12

Gene sequence:

>1272_bases
ATGAGTCAAGTCATTTCCGTACGCCGCCCGGCCGCCGACGCTTCGTTCGGCCAGGCGCTGAAGAATGCCGTGGCCGCCGC
GATCCTGACGGCGATCCTCACGGTGCCGGTGCTCGGGCTGCAGCTGAAGCTCGACGGTTATCAGGTCGTGCTCGAGCGCC
ACTGGCGCCCGGTATGGATCGCGGTCGCGGCCGTGTTCCTGTTCCAGCTGTTCAAGCCGTGGCTGCTGCGCGCGAAGTCC
GCGGTGAAGCTGCCCGCGGTGCCCGCGATGGGCGCGCGCCAGCAGCGCGCGATCATCTGGGTGCTGCTCGCGGTCGGGCT
CGTGTGGCCGTTCGTCGGTTCGCGCGGCGCAGTCGACGTCGCGACGCTCGCGCTGATCTACGTGATTCTCGGTCTCGGGC
TGAACATCGTCGTCGGCTTCGCGGGGCTGCTCGATCTCGGCTATGTCGGGTTCTACGCGGTCGGCGGCTATACGTACGCG
ATGCTGAACCAGTATTTCGGGCTCACGTTCTGGGAGTGCCTGCCGATCGCGGCGATCGCGTCGGCGACGTTCGGCTTCCT
GCTCGGCTTTCCGGTGCTGCGCCTGCGCGGCGACTATCTCGCGATCGTCACGCTCGGCTTCGGCGAAATCATCCGCCTGC
TCGCCAACAACCTGACGAGCCTCACCGGCGGCCCGGACGGCATTTCCGGCATTCCGAAGCCGACCGTGTTCGGCTTCGAG
ATGGCGCGTTCGGCAAGCGTCGAAGGCGCGAAGACCTTCCATGAACTGATCGGCCTCGAATACAGCGGCGAGCACATGGT
GATCTTCCTGTATCTGCTCGCGCTGCTGCTGGTCGGCTTCACGCTGTTCGTGACGAGCCGCCTGATCCGCATGCCGATGG
GCCGCGCATGGGAAGCGCTGCGCGACGACGAGATCGCATGCCGTTCGCTCGGCCTGAATCCGACGCGCATCAAGCTCTCG
GCGTTCACGCTCGGCGCCGCGTTCGCCGGTATCGGCGGCGCGTTTTTTGCCGCGCGTCAGGGCCTCGTGAATCCGGAGTC
GTTCACGTTCATCGAATCGGCGCTGATTCTCGCAATCGTCGTGCTCGGCGGGATGGGTTCGCAGCTCGGCGTGATCCTCG
CGGCGATCCTGCTGACCGTGCTGCCGGAAGTCGCGCGCGGCTTTGCCGAGTACCGGATGCTGATCTTCGGTCTCGTGATG
GTGTTGATGATGATGTGGCGTCCGCAGGGCCTGCTGCCCGCGAGCCGTCCCCACGTGGAGTTGCCGCAATGA

Upstream 100 bases:

>100_bases
AGGACGTCGTCGCGTTCGGCCTGCTCGTGCTGATCCTGCTCTTCCGCCCGACCGGCCTGCTCGGCAAGTCGGACATCGAA
AAGGTCTGAGGGATACGCAG

Downstream 100 bases:

>100_bases
GCGCGAATGCAGAACTGTTGAAGGTCGCCGGATTGCAGATGCGCTTCGGCGGGTTGCTTGCGGTCGACGGCATCGACTTC
GACGTGCGTCGTGACGAGGT

Product: leucine/isoleucine/valine transporter permease subunit

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSQVISVRRPAADASFGQALKNAVAAAILTAILTVPVLGLQLKLDGYQVVLERHWRPVWIAVAAVFLFQLFKPWLLRAKS
AVKLPAVPAMGARQQRAIIWVLLAVGLVWPFVGSRGAVDVATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTYA
MLNQYFGLTFWECLPIAAIASATFGFLLGFPVLRLRGDYLAIVTLGFGEIIRLLANNLTSLTGGPDGISGIPKPTVFGFE
MARSASVEGAKTFHELIGLEYSGEHMVIFLYLLALLLVGFTLFVTSRLIRMPMGRAWEALRDDEIACRSLGLNPTRIKLS
AFTLGAAFAGIGGAFFAARQGLVNPESFTFIESALILAIVVLGGMGSQLGVILAAILLTVLPEVARGFAEYRMLIFGLVM
VLMMMWRPQGLLPASRPHVELPQ

Sequences:

>Translated_423_residues
MSQVISVRRPAADASFGQALKNAVAAAILTAILTVPVLGLQLKLDGYQVVLERHWRPVWIAVAAVFLFQLFKPWLLRAKS
AVKLPAVPAMGARQQRAIIWVLLAVGLVWPFVGSRGAVDVATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTYA
MLNQYFGLTFWECLPIAAIASATFGFLLGFPVLRLRGDYLAIVTLGFGEIIRLLANNLTSLTGGPDGISGIPKPTVFGFE
MARSASVEGAKTFHELIGLEYSGEHMVIFLYLLALLLVGFTLFVTSRLIRMPMGRAWEALRDDEIACRSLGLNPTRIKLS
AFTLGAAFAGIGGAFFAARQGLVNPESFTFIESALILAIVVLGGMGSQLGVILAAILLTVLPEVARGFAEYRMLIFGLVM
VLMMMWRPQGLLPASRPHVELPQ
>Mature_422_residues
SQVISVRRPAADASFGQALKNAVAAAILTAILTVPVLGLQLKLDGYQVVLERHWRPVWIAVAAVFLFQLFKPWLLRAKSA
VKLPAVPAMGARQQRAIIWVLLAVGLVWPFVGSRGAVDVATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTYAM
LNQYFGLTFWECLPIAAIASATFGFLLGFPVLRLRGDYLAIVTLGFGEIIRLLANNLTSLTGGPDGISGIPKPTVFGFEM
ARSASVEGAKTFHELIGLEYSGEHMVIFLYLLALLLVGFTLFVTSRLIRMPMGRAWEALRDDEIACRSLGLNPTRIKLSA
FTLGAAFAGIGGAFFAARQGLVNPESFTFIESALILAIVVLGGMGSQLGVILAAILLTVLPEVARGFAEYRMLIFGLVMV
LMMMWRPQGLLPASRPHVELPQ

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=412, Percent_Identity=59.2233009708738, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 45600; Mature: 45469

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure 
SQVISVRRPAADASFGQALKNAVAAAILTAILTVPVLGLQLKLDGYQVVLERHWRPVWI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHHHCCCHHHH
AVAAVFLFQLFKPWLLRAKSAVKLPAVPAMGARQQRAIIWVLLAVGLVWPFVGSRGAVDV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
ATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTYAMLNQYFGLTFWECLPIAAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SATFGFLLGFPVLRLRGDYLAIVTLGFGEIIRLLANNLTSLTGGPDGISGIPKPTVFGFE
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
MARSASVEGAKTFHELIGLEYSGEHMVIFLYLLALLLVGFTLFVTSRLIRMPMGRAWEAL
HHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RDDEIACRSLGLNPTRIKLSAFTLGAAFAGIGGAFFAARQGLVNPESFTFIESALILAIV
CCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VLGGMGSQLGVILAAILLTVLPEVARGFAEYRMLIFGLVMVLMMMWRPQGLLPASRPHVE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]