| Definition | Burkholderia multivorans ATCC 17616 chromosome 2, complete genome. |
|---|---|
| Accession | NC_010805 |
| Length | 2,473,162 |
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The map label for this gene is cbr [H]
Identifier: 189353623
GI number: 189353623
Start: 1883182
End: 1884969
Strand: Direct
Name: cbr [H]
Synonym: BMULJ_04867
Alternate gene names: 189353623
Gene position: 1883182-1884969 (Clockwise)
Preceding gene: 189353622
Following gene: 189353624
Centisome position: 76.14
GC content: 70.64
Gene sequence:
>1788_bases ATGCAGCCTCTTGCCGACGAAGCGCCGCTGGCCCTGTTCGAATCGCTTCACAACGAAACCGCCATCGCCTCCGGCGACCT GACGCTCGCGGTCAGGACCTGGGGCGATCCGGCGCGCTCGCCGGTCGTGCTCGTGCACGGCTACCCCGACGACAGTAGCG TCTGGCAGCAGGTCGCGCCGCTGCTTGCGCGCAAGCATTACGTGATCGCCTACGACGTGCGCGGCGCCGGCCTCTCGAGC GCGCCGAAGCGCACGGCCGACTACCGGCTCGCGAAGCTGACCGACGATTTCGTCGCGGTGATCGACGCGCTCTGCCCCGG CCGCGCCGTGCATCTTGTCGCGCACGACTGGGGCTCGATTCAGGGATGGGAATTCGTCACCGAGCCGCGGCTCGCCGGCC GCATCGCGTCGTACACGTCGTGCTCGGGGCCATGCCTCGATCACGTCGGCTTCTGGCTGCGCGAACGCTTGCTGCACCCG ACGCCCGCGTCGCTCGGCAAGCTCGGGGGCCAGCTCGTACGCTCGTGGTACGTCTACCTGTTTCACCTGCCCTTCATTCC CGAACTCGGCTGGCGGCTCTGGCTCGGTCGCGCGTGGCCGCGCCTGCTGCGCCGGATCGAGAAGACGCCCGTCGCGCCGC GCGCGACGCAGGCCGACGACGGCGCACGCGGCGTGCGCCTCTATCGCGCGAACTTCATCCGCTGCCTGTTCACGCCGCGC CAACGCTACGCGCATGCGCCGGTGCAGACGGTCGTGCCGCTCGGCGACAAATACGTGAGCCCCGCGCTGTCCGAGCATCT GTCGCGCTGGGTGCCGCAGTACTACCGGCGCGAAGTCGCGGCCGGCCACTGGCTGCCGCTCGCCGATCCCGCGCGCTTTG CCGGTCTCGCCGAACAACTGATCGACGCGGTCGAATCGGGCGACGAGCCGCCCGCGCTCGCGAACGCGCGCCGCCGCGCG ACGAGCGGCCGCTTCAGCGGCAAGGTCGCGGTCGTCACCGGCGCCGGCAGCGGCATTGGCCGTTGCGCAGCGCTCGCGTT CGCGCGCGAAGGCGCGACCGTCGTCGCCGTCGACATCGATCTCGCGAGCACCGAACGCACCGCGCTGCTGATCGGACTGA TCGGCGCGCAGGCGCATGCGAAGCGCGTCGACGTCGGCTCGGCCGACGAGATGGAAGCACTCGCGACGTGGGTCGGCAGC GCACTCGGCGGCGCCGACGTCGTGATCAACAACGCGGGCATCGGCATGGCCGGCGGCATCCTCGATACGAGCACGCAGCA CTGGCAGCGCATCCTGCACGTGAATCTGTGGGGCGTGATCCACGGCTCGCGGCTGTTCGCGCAGCAGATGGCCGCGCGCG GCACCGGCGGCCACATCGTCAACACCGCGTCGGCCGCCGCGTTCGGTCCGTCGCGCGACCTGCCCGCGTATGCGACGACG AAAGCCGCCGTACTGATGCTCAGCGAATGCATGCGCGCGGAACTCGCGGAGCAAGGCATCGGCGTGACGGCCGTGTGTCC GGGCTTTGCGGAGACCGGCATCATGGCGTCGACGCAATACGCGGGCGCCAACGCGCAGGACGAAGCACGCCTGCGCAAGC GCGCGACGAAGCTCTACCGGATGCGCGGCCTGAAGCCCGAAACCGTCGCGCAGGCGATGGTCGACAGCGTGCTACGCAAC CGCCCCGTCGTCGCGGTCGGCGGCGAAGCGCACGCGCTGCGCTTCGTCGGCCGCTTCATGCCGTGGCTCGGACGCATGAT CGCCCGCGTCAGCATGGCATCGCATTGA
Upstream 100 bases:
>100_bases CAACGTCGGCTGGCTGAGCGCGCGCAGACCGTCGCGACCGTGTCGGCTGCGGCCTGACACGCACCGCGCCCCTGATCGAT TTCTCGACGACGGACTCACG
Downstream 100 bases:
>100_bases CGGCGCCGCGCGCCGCACAGGGAGACACCGATGACCGATACCGCCAAATATCACAAGATCAAGGCCCGGCACGTGAAGTT CGACTTCAGCAACACGCCGA
Product: short chain dehydrogenase
Products: 3alpha12alpha-dihydroxy-oxobeta-cholanate; NADH [C]
Alternate protein names: NA
Number of amino acids: Translated: 595; Mature: 595
Protein sequence:
>595_residues MQPLADEAPLALFESLHNETAIASGDLTLAVRTWGDPARSPVVLVHGYPDDSSVWQQVAPLLARKHYVIAYDVRGAGLSS APKRTADYRLAKLTDDFVAVIDALCPGRAVHLVAHDWGSIQGWEFVTEPRLAGRIASYTSCSGPCLDHVGFWLRERLLHP TPASLGKLGGQLVRSWYVYLFHLPFIPELGWRLWLGRAWPRLLRRIEKTPVAPRATQADDGARGVRLYRANFIRCLFTPR QRYAHAPVQTVVPLGDKYVSPALSEHLSRWVPQYYRREVAAGHWLPLADPARFAGLAEQLIDAVESGDEPPALANARRRA TSGRFSGKVAVVTGAGSGIGRCAALAFAREGATVVAVDIDLASTERTALLIGLIGAQAHAKRVDVGSADEMEALATWVGS ALGGADVVINNAGIGMAGGILDTSTQHWQRILHVNLWGVIHGSRLFAQQMAARGTGGHIVNTASAAAFGPSRDLPAYATT KAAVLMLSECMRAELAEQGIGVTAVCPGFAETGIMASTQYAGANAQDEARLRKRATKLYRMRGLKPETVAQAMVDSVLRN RPVVAVGGEAHALRFVGRFMPWLGRMIARVSMASH
Sequences:
>Translated_595_residues MQPLADEAPLALFESLHNETAIASGDLTLAVRTWGDPARSPVVLVHGYPDDSSVWQQVAPLLARKHYVIAYDVRGAGLSS APKRTADYRLAKLTDDFVAVIDALCPGRAVHLVAHDWGSIQGWEFVTEPRLAGRIASYTSCSGPCLDHVGFWLRERLLHP TPASLGKLGGQLVRSWYVYLFHLPFIPELGWRLWLGRAWPRLLRRIEKTPVAPRATQADDGARGVRLYRANFIRCLFTPR QRYAHAPVQTVVPLGDKYVSPALSEHLSRWVPQYYRREVAAGHWLPLADPARFAGLAEQLIDAVESGDEPPALANARRRA TSGRFSGKVAVVTGAGSGIGRCAALAFAREGATVVAVDIDLASTERTALLIGLIGAQAHAKRVDVGSADEMEALATWVGS ALGGADVVINNAGIGMAGGILDTSTQHWQRILHVNLWGVIHGSRLFAQQMAARGTGGHIVNTASAAAFGPSRDLPAYATT KAAVLMLSECMRAELAEQGIGVTAVCPGFAETGIMASTQYAGANAQDEARLRKRATKLYRMRGLKPETVAQAMVDSVLRN RPVVAVGGEAHALRFVGRFMPWLGRMIARVSMASH >Mature_595_residues MQPLADEAPLALFESLHNETAIASGDLTLAVRTWGDPARSPVVLVHGYPDDSSVWQQVAPLLARKHYVIAYDVRGAGLSS APKRTADYRLAKLTDDFVAVIDALCPGRAVHLVAHDWGSIQGWEFVTEPRLAGRIASYTSCSGPCLDHVGFWLRERLLHP TPASLGKLGGQLVRSWYVYLFHLPFIPELGWRLWLGRAWPRLLRRIEKTPVAPRATQADDGARGVRLYRANFIRCLFTPR QRYAHAPVQTVVPLGDKYVSPALSEHLSRWVPQYYRREVAAGHWLPLADPARFAGLAEQLIDAVESGDEPPALANARRRA TSGRFSGKVAVVTGAGSGIGRCAALAFAREGATVVAVDIDLASTERTALLIGLIGAQAHAKRVDVGSADEMEALATWVGS ALGGADVVINNAGIGMAGGILDTSTQHWQRILHVNLWGVIHGSRLFAQQMAARGTGGHIVNTASAAAFGPSRDLPAYATT KAAVLMLSECMRAELAEQGIGVTAVCPGFAETGIMASTQYAGANAQDEARLRKRATKLYRMRGLKPETVAQAMVDSVLRN RPVVAVGGEAHALRFVGRFMPWLGRMIARVSMASH
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI142976729, Length=281, Percent_Identity=25.6227758007117, Blast_Score=94, Evalue=3e-19, Organism=Homo sapiens, GI210032110, Length=259, Percent_Identity=25.8687258687259, Blast_Score=94, Evalue=5e-19, Organism=Homo sapiens, GI40807363, Length=268, Percent_Identity=27.2388059701493, Blast_Score=93, Evalue=7e-19, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=31.5, Blast_Score=91, Evalue=4e-18, Organism=Homo sapiens, GI25282469, Length=292, Percent_Identity=25, Blast_Score=89, Evalue=1e-17, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=30.7053941908714, Blast_Score=87, Evalue=5e-17, Organism=Homo sapiens, GI15277342, Length=197, Percent_Identity=34.010152284264, Blast_Score=87, Evalue=6e-17, Organism=Homo sapiens, GI66933014, Length=190, Percent_Identity=32.6315789473684, Blast_Score=85, Evalue=2e-16, Organism=Homo sapiens, GI32483357, Length=204, Percent_Identity=29.9019607843137, Blast_Score=83, Evalue=8e-16, Organism=Homo sapiens, GI7705925, Length=197, Percent_Identity=34.010152284264, Blast_Score=79, Evalue=2e-14, Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=32.8125, Blast_Score=77, Evalue=3e-14, Organism=Homo sapiens, GI33667109, Length=247, Percent_Identity=28.7449392712551, Blast_Score=77, Evalue=6e-14, Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=30.1020408163265, Blast_Score=76, Evalue=7e-14, Organism=Homo sapiens, GI4758504, Length=202, Percent_Identity=31.1881188118812, Blast_Score=74, Evalue=4e-13, Organism=Homo sapiens, GI224922801, Length=164, Percent_Identity=32.3170731707317, Blast_Score=72, Evalue=2e-12, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=3e-12, Organism=Homo sapiens, GI4503817, Length=254, Percent_Identity=25.1968503937008, Blast_Score=71, Evalue=3e-12, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=28.021978021978, Blast_Score=70, Evalue=6e-12, Organism=Escherichia coli, GI1787905, Length=185, Percent_Identity=37.2972972972973, Blast_Score=99, Evalue=1e-21, Organism=Escherichia coli, GI1789208, Length=210, Percent_Identity=30.952380952381, Blast_Score=97, Evalue=2e-21, Organism=Escherichia coli, GI87082100, Length=222, Percent_Identity=30.6306306306306, Blast_Score=89, Evalue=8e-19, Organism=Escherichia coli, GI1789378, Length=222, Percent_Identity=31.5315315315315, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI2367175, Length=231, Percent_Identity=32.034632034632, Blast_Score=84, Evalue=2e-17, Organism=Escherichia coli, GI1788459, Length=182, Percent_Identity=32.4175824175824, Blast_Score=84, Evalue=3e-17, Organism=Escherichia coli, GI1787335, Length=207, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=3e-16, Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=29.2553191489362, Blast_Score=78, Evalue=1e-15, Organism=Escherichia coli, GI1786812, Length=210, Percent_Identity=33.8095238095238, Blast_Score=75, Evalue=2e-14, Organism=Escherichia coli, GI87082160, Length=195, Percent_Identity=27.1794871794872, Blast_Score=74, Evalue=3e-14, Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=25.5506607929515, Blast_Score=70, Evalue=4e-13, Organism=Escherichia coli, GI1789057, Length=235, Percent_Identity=28.936170212766, Blast_Score=70, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=32.4742268041237, Blast_Score=99, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17567345, Length=268, Percent_Identity=27.6119402985075, Blast_Score=96, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560150, Length=199, Percent_Identity=33.1658291457286, Blast_Score=95, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17564282, Length=244, Percent_Identity=27.8688524590164, Blast_Score=94, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17555706, Length=196, Percent_Identity=33.6734693877551, Blast_Score=92, Evalue=8e-19, Organism=Caenorhabditis elegans, GI25147288, Length=195, Percent_Identity=34.3589743589744, Blast_Score=91, Evalue=1e-18, Organism=Caenorhabditis elegans, GI193203117, Length=246, Percent_Identity=27.2357723577236, Blast_Score=89, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17538480, Length=205, Percent_Identity=32.6829268292683, Blast_Score=89, Evalue=8e-18, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562990, Length=199, Percent_Identity=32.1608040201005, Blast_Score=88, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562904, Length=199, Percent_Identity=32.6633165829146, Blast_Score=88, Evalue=2e-17, Organism=Caenorhabditis elegans, GI193203115, Length=243, Percent_Identity=27.1604938271605, Blast_Score=85, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17538486, Length=235, Percent_Identity=30.2127659574468, Blast_Score=85, Evalue=9e-17, Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=30.6878306878307, Blast_Score=84, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=28.2945736434109, Blast_Score=82, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17559104, Length=199, Percent_Identity=32.1608040201005, Blast_Score=82, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71994600, Length=205, Percent_Identity=31.219512195122, Blast_Score=80, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17561402, Length=212, Percent_Identity=29.2452830188679, Blast_Score=79, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562908, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=4e-14, Organism=Caenorhabditis elegans, GI115534694, Length=198, Percent_Identity=31.8181818181818, Blast_Score=76, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17544670, Length=206, Percent_Identity=30.5825242718447, Blast_Score=73, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17565030, Length=199, Percent_Identity=32.1608040201005, Blast_Score=72, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17531453, Length=199, Percent_Identity=30.1507537688442, Blast_Score=72, Evalue=8e-13, Organism=Caenorhabditis elegans, GI193204405, Length=201, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17554012, Length=160, Percent_Identity=28.125, Blast_Score=71, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17562906, Length=201, Percent_Identity=29.8507462686567, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560332, Length=204, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17538182, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562910, Length=202, Percent_Identity=30.6930693069307, Blast_Score=69, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17560676, Length=230, Percent_Identity=22.1739130434783, Blast_Score=69, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17560220, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=8e-11, Organism=Drosophila melanogaster, GI28571387, Length=204, Percent_Identity=33.8235294117647, Blast_Score=99, Evalue=9e-21, Organism=Drosophila melanogaster, GI23397609, Length=190, Percent_Identity=35.7894736842105, Blast_Score=97, Evalue=3e-20, Organism=Drosophila melanogaster, GI24639444, Length=196, Percent_Identity=34.1836734693878, Blast_Score=94, Evalue=2e-19, Organism=Drosophila melanogaster, GI281364892, Length=199, Percent_Identity=35.1758793969849, Blast_Score=94, Evalue=3e-19, Organism=Drosophila melanogaster, GI24644339, Length=205, Percent_Identity=31.7073170731707, Blast_Score=90, Evalue=5e-18, Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=31.6062176165803, Blast_Score=86, Evalue=6e-17, Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=31.2169312169312, Blast_Score=85, Evalue=2e-16, Organism=Drosophila melanogaster, GI21358495, Length=266, Percent_Identity=25.5639097744361, Blast_Score=84, Evalue=2e-16, Organism=Drosophila melanogaster, GI21356301, Length=266, Percent_Identity=25.9398496240602, Blast_Score=84, Evalue=2e-16, Organism=Drosophila melanogaster, GI281364494, Length=204, Percent_Identity=32.843137254902, Blast_Score=84, Evalue=3e-16, Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=3e-16, Organism=Drosophila melanogaster, GI116007234, Length=205, Percent_Identity=33.6585365853659, Blast_Score=82, Evalue=8e-16, Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=32.4607329842932, Blast_Score=82, Evalue=2e-15, Organism=Drosophila melanogaster, GI24641232, Length=205, Percent_Identity=31.219512195122, Blast_Score=80, Evalue=3e-15, Organism=Drosophila melanogaster, GI24665243, Length=212, Percent_Identity=29.7169811320755, Blast_Score=80, Evalue=3e-15, Organism=Drosophila melanogaster, GI17737361, Length=200, Percent_Identity=30.5, Blast_Score=80, Evalue=6e-15, Organism=Drosophila melanogaster, GI24665247, Length=214, Percent_Identity=30.8411214953271, Blast_Score=78, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007236, Length=211, Percent_Identity=29.3838862559242, Blast_Score=78, Evalue=2e-14, Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=30.8080808080808, Blast_Score=78, Evalue=2e-14, Organism=Drosophila melanogaster, GI24640492, Length=203, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=4e-14, Organism=Drosophila melanogaster, GI221331216, Length=200, Percent_Identity=32, Blast_Score=76, Evalue=8e-14, Organism=Drosophila melanogaster, GI24663911, Length=221, Percent_Identity=31.6742081447964, Blast_Score=75, Evalue=1e-13, Organism=Drosophila melanogaster, GI24648693, Length=206, Percent_Identity=32.5242718446602, Blast_Score=73, Evalue=7e-13, Organism=Drosophila melanogaster, GI21355889, Length=206, Percent_Identity=32.5242718446602, Blast_Score=73, Evalue=7e-13, Organism=Drosophila melanogaster, GI116007232, Length=181, Percent_Identity=33.7016574585635, Blast_Score=71, Evalue=2e-12, Organism=Drosophila melanogaster, GI24641388, Length=213, Percent_Identity=31.924882629108, Blast_Score=71, Evalue=3e-12, Organism=Drosophila melanogaster, GI24581726, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12, Organism=Drosophila melanogaster, GI21355319, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=5e-12, Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=31.4432989690722, Blast_Score=69, Evalue=7e-12, Organism=Drosophila melanogaster, GI24648944, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007238, Length=191, Percent_Identity=29.8429319371728, Blast_Score=68, Evalue=2e-11, Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000073 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]
EC number: 1.1.1.159 [C]
Molecular weight: Translated: 64232; Mature: 64232
Theoretical pI: Translated: 9.73; Mature: 9.73
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQPLADEAPLALFESLHNETAIASGDLTLAVRTWGDPARSPVVLVHGYPDDSSVWQQVAP CCCCCCCCHHHHHHHHCCCCEEECCCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHH LLARKHYVIAYDVRGAGLSSAPKRTADYRLAKLTDDFVAVIDALCPGRAVHLVAHDWGSI HHHCCCEEEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC QGWEFVTEPRLAGRIASYTSCSGPCLDHVGFWLRERLLHPTPASLGKLGGQLVRSWYVYL CCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH FHLPFIPELGWRLWLGRAWPRLLRRIEKTPVAPRATQADDGARGVRLYRANFIRCLFTPR HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHEEECCH QRYAHAPVQTVVPLGDKYVSPALSEHLSRWVPQYYRREVAAGHWLPLADPARFAGLAEQL HHHHCCCHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH IDAVESGDEPPALANARRRATSGRFSGKVAVVTGAGSGIGRCAALAFAREGATVVAVDID HHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEEE LASTERTALLIGLIGAQAHAKRVDVGSADEMEALATWVGSALGGADVVINNAGIGMAGGI ECCCCCCEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC LDTSTQHWQRILHVNLWGVIHGSRLFAQQMAARGTGGHIVNTASAAAFGPSRDLPAYATT CCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCEEECCCHHCCCCCCCCCCHHHH KAAVLMLSECMRAELAEQGIGVTAVCPGFAETGIMASTQYAGANAQDEARLRKRATKLYR HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHH MRGLKPETVAQAMVDSVLRNRPVVAVGGEAHALRFVGRFMPWLGRMIARVSMASH HCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MQPLADEAPLALFESLHNETAIASGDLTLAVRTWGDPARSPVVLVHGYPDDSSVWQQVAP CCCCCCCCHHHHHHHHCCCCEEECCCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHH LLARKHYVIAYDVRGAGLSSAPKRTADYRLAKLTDDFVAVIDALCPGRAVHLVAHDWGSI HHHCCCEEEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC QGWEFVTEPRLAGRIASYTSCSGPCLDHVGFWLRERLLHPTPASLGKLGGQLVRSWYVYL CCCEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH FHLPFIPELGWRLWLGRAWPRLLRRIEKTPVAPRATQADDGARGVRLYRANFIRCLFTPR HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHEEECCH QRYAHAPVQTVVPLGDKYVSPALSEHLSRWVPQYYRREVAAGHWLPLADPARFAGLAEQL HHHHCCCHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH IDAVESGDEPPALANARRRATSGRFSGKVAVVTGAGSGIGRCAALAFAREGATVVAVDID HHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEEE LASTERTALLIGLIGAQAHAKRVDVGSADEMEALATWVGSALGGADVVINNAGIGMAGGI ECCCCCCEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC LDTSTQHWQRILHVNLWGVIHGSRLFAQQMAARGTGGHIVNTASAAAFGPSRDLPAYATT CCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCEEECCCHHCCCCCCCCCCHHHH KAAVLMLSECMRAELAEQGIGVTAVCPGFAETGIMASTQYAGANAQDEARLRKRATKLYR HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHH MRGLKPETVAQAMVDSVLRNRPVVAVGGEAHALRFVGRFMPWLGRMIARVSMASH HCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: 2-Mercaptoethanol; Dithiothreitol; NAD+; NADH [C]
Metal ions: CaCl2; KCl; MnCl2; NaCl [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.8 {cholic} 0.085 {glycochenodeoxycholic} 0.24 {taurochenodeoxycholic} 1 {glycocholic} 0.06 {chenodeoxycholic} [C]
Substrates: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate!; NAD [C]
Specific reaction: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate! + NAD+ = 3alpha12alpha-dihydroxy-oxobeta-cholanate + NADH [C]
General reaction: Redox reaction [C]
Inhibitor: Ascorbicacid; BaCl2; CoCl2; CuCl2; EDTA; FeCl3; HgCl2; MgCl2; NH4Cl; Potassiumoxalate; Sodiumcitrate; Sodiumlaurylsulfate; Sodiumperchlorate; Sodiumperiodate; Sodiumpersulfate; TritonX-100; Tween; ZnCl2 [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]