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The map label for this gene is glsA [H]

Identifier: 189353597

GI number: 189353597

Start: 1851996

End: 1852910

Strand: Direct

Name: glsA [H]

Synonym: BMULJ_04841

Alternate gene names: 189353597

Gene position: 1851996-1852910 (Clockwise)

Preceding gene: 189353594

Following gene: 189353600

Centisome position: 74.88

GC content: 65.14

Gene sequence:

>915_bases
ATGAACTACCAACCGATTCTCGAACGCATCCATACCGAACTCGCCCCCTGGATCGGCCAGGGCCGCGTGGCCGACTACAT
TCCCGAGCTCGCGAAAGTACCCGCCGACAAGTTCGGGATGGCGGTCGTCACGCTCGACGGCAACGTTTACACGGTCGGCG
ACGCGCAGGAGCGCTTCTCGATCCAGAGCATCTCGAAGCTGTTCGCGTGCACGCTCGCGTTCCAGCTGCTCGGCGACGCG
CTGTGGGAACGCGTCGGCCGCGAACCGTCCGGCACCGCGTTCAATTCGCTCGTGCAGCTCGAAAGCGAGCGCGGCAAGCC
GCGCAATCCGTTCATCAACGCGGGCGCGCTCGTCGTCACCGACGTGCTGTGCCGCCGCTTCGTGAAGGCGGAAACCGCGC
TCGTCGAATTCGTGCGGCGACTGATCGGCGCGAACGACATCGACTACGATTCGCGCGTCGCGCTGTCGGAGCTGCAGCAC
GCGGAGCGCAATCGCGCGATGGCGCATTTCATGGCGAGCTTCGGCAACATGCAGATGCCGCCGGAAACGGTCGTCGATGC
GTATTGCCGTCAGTGCGCGATCACGATGAACTGCGTCGAGCTCGCGCGCGCCGCGTTGTTTCTTGCGAACGGGGGTGTGG
CGCCTGCGACCGGGGAGAGGATCGTCGATCCGAGTTCGGCGAAACGGCTGTCGGCGCTGATGCTGACCTGCGGCACTTAT
GACGCGGCCGGGGATTTCGTCTATCGCGTCGGGCTGCCGGCGAAGAGCGGCGTCGGCGGCGGGATCGTTGCGGTGCTGCC
CGGCGAGATGGCGGTCTGCGTGTGGGCGCCGGGGCTCGATGCGAACGGGAATTCGTTGGCAGGGACGTTGGCGTTGGAGT
GGTTGACGACTTATTCGGGAAGGTCGATTTTTTGA

Upstream 100 bases:

>100_bases
GACAGGCGGCGCGACGCCGGCCTGCTTGACGAATCGACGCCGAAACGGTTCCATACGGGCTCGCCGGAATCCGGGCGGCG
CGCCGCCCTTGCCTGATCTG

Downstream 100 bases:

>100_bases
GGGGGGGAAGTCGGGGGCGCCTTATCTGCCGCAGCGGCGGCAGATTTGCATGGGCGCGCATCGGCACGCTCAATGGGGAA
CTCGGCCAACGGCAGCAATC

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNYQPILERIHTELAPWIGQGRVADYIPELAKVPADKFGMAVVTLDGNVYTVGDAQERFSIQSISKLFACTLAFQLLGDA
LWERVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVTDVLCRRFVKAETALVEFVRRLIGANDIDYDSRVALSELQH
AERNRAMAHFMASFGNMQMPPETVVDAYCRQCAITMNCVELARAALFLANGGVAPATGERIVDPSSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWAPGLDANGNSLAGTLALEWLTTYSGRSIF

Sequences:

>Translated_304_residues
MNYQPILERIHTELAPWIGQGRVADYIPELAKVPADKFGMAVVTLDGNVYTVGDAQERFSIQSISKLFACTLAFQLLGDA
LWERVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVTDVLCRRFVKAETALVEFVRRLIGANDIDYDSRVALSELQH
AERNRAMAHFMASFGNMQMPPETVVDAYCRQCAITMNCVELARAALFLANGGVAPATGERIVDPSSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWAPGLDANGNSLAGTLALEWLTTYSGRSIF
>Mature_304_residues
MNYQPILERIHTELAPWIGQGRVADYIPELAKVPADKFGMAVVTLDGNVYTVGDAQERFSIQSISKLFACTLAFQLLGDA
LWERVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVTDVLCRRFVKAETALVEFVRRLIGANDIDYDSRVALSELQH
AERNRAMAHFMASFGNMQMPPETVVDAYCRQCAITMNCVELARAALFLANGGVAPATGERIVDPSSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWAPGLDANGNSLAGTLALEWLTTYSGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=275, Percent_Identity=38.5454545454545, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI20336214, Length=299, Percent_Identity=33.4448160535117, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1787804, Length=300, Percent_Identity=54.3333333333333, Blast_Score=323, Evalue=9e-90,
Organism=Escherichia coli, GI1786693, Length=302, Percent_Identity=36.7549668874172, Blast_Score=201, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17507019, Length=282, Percent_Identity=39.0070921985816, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17532727, Length=284, Percent_Identity=39.0845070422535, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI193204073, Length=281, Percent_Identity=36.6548042704626, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI193204075, Length=283, Percent_Identity=36.3957597173145, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24653164, Length=289, Percent_Identity=38.0622837370242, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24653162, Length=289, Percent_Identity=38.0622837370242, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI281363241, Length=289, Percent_Identity=38.0622837370242, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24653156, Length=289, Percent_Identity=38.0622837370242, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI281363239, Length=289, Percent_Identity=38.0622837370242, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24653166, Length=289, Percent_Identity=38.0622837370242, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24653158, Length=289, Percent_Identity=38.0622837370242, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI116008307, Length=289, Percent_Identity=38.0622837370242, Blast_Score=193, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32770; Mature: 32770

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYQPILERIHTELAPWIGQGRVADYIPELAKVPADKFGMAVVTLDGNVYTVGDAQERFS
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCEEEEEECCCEEECCCHHHHHH
IQSISKLFACTLAFQLLGDALWERVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
DVLCRRFVKAETALVEFVRRLIGANDIDYDSRVALSELQHAERNRAMAHFMASFGNMQMP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PETVVDAYCRQCAITMNCVELARAALFLANGGVAPATGERIVDPSSAKRLSALMLTCGTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWAPGLDANGNSLAGTLALEWLTTYSG
CCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCC
RSIF
CCCC
>Mature Secondary Structure
MNYQPILERIHTELAPWIGQGRVADYIPELAKVPADKFGMAVVTLDGNVYTVGDAQERFS
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCEEEEEECCCEEECCCHHHHHH
IQSISKLFACTLAFQLLGDALWERVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
DVLCRRFVKAETALVEFVRRLIGANDIDYDSRVALSELQHAERNRAMAHFMASFGNMQMP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PETVVDAYCRQCAITMNCVELARAALFLANGGVAPATGERIVDPSSAKRLSALMLTCGTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWAPGLDANGNSLAGTLALEWLTTYSG
CCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCC
RSIF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA