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The map label for this gene is restA [H]

Identifier: 189353596

GI number: 189353596

Start: 1851061

End: 1851768

Strand: Reverse

Name: restA [H]

Synonym: BMULJ_04840

Alternate gene names: 189353596

Gene position: 1851768-1851061 (Counterclockwise)

Preceding gene: 189353598

Following gene: 189353595

Centisome position: 74.87

GC content: 65.96

Gene sequence:

>708_bases
ATGTCTTTCCGCATCCTGCTCGTCGAAGACGACGTCCGCCTGTCCACGCTGATCGCCGGCTATCTGCGCAAGAACGACTA
TGAAGTCGACACTGTGCTGCACGGCGATGCCGCGGTGCCGGCGATCCTGTCCACGCGCCCGGATCTCGTCATTCTCGACG
TGAACCTGCCCGGCAAGGACGGCTTCGAAATCTGCCGCGACGCGCGTCAGCACTACGACGGCGTCATCATCATGGTGACG
GCGCGTGACGAGCCGTTCGACGAACTGCTCGGCCTCGAGATCGGCGCCGACGATTACGTGCACAAGCCGGTCGAGCCGCG
CATCCTGCTCGCACGGATCAAGGCGCAATTGCGGCGCGCGCCCGCGCGTGTCGCGGAAGGCGCCCCGCAGCCGGAGCGCT
ATACGTTCGGCAAGTTCTCGATCGACCGCACCGACCGCAGCGTCGTGCTGCCCGACGGCAGCACGCCCGATCTGACCTCC
GCGGAATTCGACCTGCTGTGGGTGCTGGTCTGCCGGGCCGGCGAAGTGGTGAGCCGCGACGACCTGATGCTGCAGCTGCG
CGGCGTCGAATTCGACGGGCTCGACCGGACGATCGACGGCCGCATCTCGAAGCTGCGTCGCAAGCTGCGCGACGACGCGA
GCAACCCGCAGCGGATCAAGACGATCCGCAGCAAGGGTTACCAGTTCAGCAAGCACGCATGGGAATGA

Upstream 100 bases:

>100_bases
GGTCCGCAAGCGCAGTATCATGCGGTACGTTTCGGCCGCCGGCCGGCCGCGGGCGCCGTCCGCACCGCCGCGGTTTCCCC
GTACGAATTCACCGTTACCC

Downstream 100 bases:

>100_bases
TCGTGCGCTCGCCCACGAACGTGCGTCGGCGTGCGGCGGCTGCGTCCGGCAGCGACGGCGGGGTGCCGCGATGATCCACA
AGTCGCGCTCGCAACCGAAT

Product: OmpR family two-component system response regulator RstA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSFRILLVEDDVRLSTLIAGYLRKNDYEVDTVLHGDAAVPAILSTRPDLVILDVNLPGKDGFEICRDARQHYDGVIIMVT
ARDEPFDELLGLEIGADDYVHKPVEPRILLARIKAQLRRAPARVAEGAPQPERYTFGKFSIDRTDRSVVLPDGSTPDLTS
AEFDLLWVLVCRAGEVVSRDDLMLQLRGVEFDGLDRTIDGRISKLRRKLRDDASNPQRIKTIRSKGYQFSKHAWE

Sequences:

>Translated_235_residues
MSFRILLVEDDVRLSTLIAGYLRKNDYEVDTVLHGDAAVPAILSTRPDLVILDVNLPGKDGFEICRDARQHYDGVIIMVT
ARDEPFDELLGLEIGADDYVHKPVEPRILLARIKAQLRRAPARVAEGAPQPERYTFGKFSIDRTDRSVVLPDGSTPDLTS
AEFDLLWVLVCRAGEVVSRDDLMLQLRGVEFDGLDRTIDGRISKLRRKLRDDASNPQRIKTIRSKGYQFSKHAWE
>Mature_234_residues
SFRILLVEDDVRLSTLIAGYLRKNDYEVDTVLHGDAAVPAILSTRPDLVILDVNLPGKDGFEICRDARQHYDGVIIMVTA
RDEPFDELLGLEIGADDYVHKPVEPRILLARIKAQLRRAPARVAEGAPQPERYTFGKFSIDRTDRSVVLPDGSTPDLTSA
EFDLLWVLVCRAGEVVSRDDLMLQLRGVEFDGLDRTIDGRISKLRRKLRDDASNPQRIKTIRSKGYQFSKHAWE

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=45.1476793248945, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=42.4242424242424, Blast_Score=164, Evalue=3e-42,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=41.2017167381974, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=34.6491228070175, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=35.6828193832599, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=38.0952380952381, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787229, Length=215, Percent_Identity=36.2790697674419, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=36.1233480176211, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=33.0434782608696, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=31.4410480349345, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=31.7391304347826, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=30.7017543859649, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26586; Mature: 26455

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRILLVEDDVRLSTLIAGYLRKNDYEVDTVLHGDAAVPAILSTRPDLVILDVNLPGKD
CCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCCEEEEEECCCCCC
GFEICRDARQHYDGVIIMVTARDEPFDELLGLEIGADDYVHKPVEPRILLARIKAQLRRA
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCEECCCHHHCCCCCCHHHHHHHHHHHHHH
PARVAEGAPQPERYTFGKFSIDRTDRSVVLPDGSTPDLTSAEFDLLWVLVCRAGEVVSRD
HHHHHCCCCCCCCEECCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
DLMLQLRGVEFDGLDRTIDGRISKLRRKLRDDASNPQRIKTIRSKGYQFSKHAWE
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SFRILLVEDDVRLSTLIAGYLRKNDYEVDTVLHGDAAVPAILSTRPDLVILDVNLPGKD
CEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCCEEEEEECCCCCC
GFEICRDARQHYDGVIIMVTARDEPFDELLGLEIGADDYVHKPVEPRILLARIKAQLRRA
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCEECCCHHHCCCCCCHHHHHHHHHHHHHH
PARVAEGAPQPERYTFGKFSIDRTDRSVVLPDGSTPDLTSAEFDLLWVLVCRAGEVVSRD
HHHHHCCCCCCCCEECCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
DLMLQLRGVEFDGLDRTIDGRISKLRRKLRDDASNPQRIKTIRSKGYQFSKHAWE
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]