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The map label for this gene is dctM [H]

Identifier: 189353594

GI number: 189353594

Start: 1848192

End: 1849814

Strand: Direct

Name: dctM [H]

Synonym: BMULJ_04838

Alternate gene names: 189353594

Gene position: 1848192-1849814 (Clockwise)

Preceding gene: 189353593

Following gene: 189353597

Centisome position: 74.73

GC content: 67.34

Gene sequence:

>1623_bases
ATGAGCCAGAGCCAGCCGCTCGCCGCGCCCGCGGTCGGCAATCCGCGCGTCACGCGCGTCATCTTCGGCATCGTCGTCGT
GCTGCTCGGCGCACTGCTCGTCGGGTTCGGCAAGAGCGCGTTCATCTTCTGCCTGCTGATCGGGCTGCTGCTGACCGGCA
TGCCGGTGTCGATCGCGCTCGGCCTCACGGTACTCACCTACCTGTTCACGATGACCGCCGTGCCGATCGAATCGGTCGCG
CTGAAGCTGTTTACCGGCATCGAGAACTTCGAGATCATGGCGATCCCGTTCTTCATCCTCGCGGGCGGCTTCCTGACGCA
TGGCGGCGTCGCCCGGCGGATGATCGCGTTCGCGACCAGCATCGTCGGTCACATGCATGGCGGCCTCGGGCTGGCCGGCG
TGCTCGCGTGCGCGATGTTCGCGGCGATTTCCGGCTCGAGCCCGGCGACCGTGATGGCGATCGGCTCGATCCTGCTGCCG
GCGATGGTTCGCCAGGGATTCCCGAACCGCTTCGGCGCCGGCGTGATCGCCACCTCCGGTTCGCTCGGCATCCTGATTCC
GCCGTCGATCGTGATGGTGCTGTACTCGGTGTCCACCAATACGTCGGTCGGCGACCTGTTTCTCGCCGGCGTCGTGCCGG
GCATTCTGCTCGCGCTGCTGCTCGGCTTCGTGACCTGGTTCATCGCGCGCCGCAACGGCTATCCACGCTTTCGCGAATTC
GACGGCCACGGCCCGCTCGCAGCGACCGGCCACGCGCTGTGGGGCCTGCTGCTCTGCGTCGCGTTCTCCGTCGTGCCGCC
CGCGGTGCTGATCGGGCTGCTCTACCTGCTGCTGCGCGCCGCCGCGCCCGGCCTCGCGGCCGGCATCGGGCTGATCGGCG
TCGCGGTGGCGCTCGCGTGGCTGTACGTCGCCTACCGCGTCGGCCGGCGCTTCACGCACCCGACGCTGCTGCGCGCCGAG
GCGCAGCGGGTCTGGACCACCTACTGGGAAAGCGTGTGGGGGCTGCTGCTGATCGTGGTCGTGATGGGCGGCATCTATTC
GGGCGTCTTCACGCCGACCGAGGCCGCCGCAATGAGCGCCGTCTACGCGTTCCTCGTGTCGACGTGCGTCTACGGCGACC
TGCCGCTCAGGCGCGTGCCGAAGGTGCTGCTCGACTCGGCCAGCATGAGCGCAATGCTGCTCTACATCATCACCAACGCA
GTGCTGTTCTCGTTCCTGATGACTTCGGAGAACATCCCGCAGCAGATGGCGAGCTGGATCCTCGACCAGGGGCTCGGCCC
GATCGGCTTCCTGCTCGTCGTGAACGTGCTGCTGCTGATGGCCGGCAACGTGATGGAGCCGTCGTCGATCGTGCTGATCA
TGGCGCCGATCCTGTTCCCCGTCGCGCGCCAGCTCGGCATCGATCCGATTCACTTCGGCATTTTGATGGTCGTGAACATG
GAAGTCGGCATGTGCCATCCGCCTGTCGGACTCAACCTGTACGTGGCGAGCGGCATCACGCGGATGGGCATTACCGAGCT
GACCGTCGCGGTCGCGCCGTGGCTCGCCGCGATGCTCGGCTTCCTGCTGCTCGTGACCTACGTGCCGGCGATCTCGCTGT
GGCTGCCGGGGCTGATGCGGTGA

Upstream 100 bases:

>100_bases
ACTTCCTGCGCAGCGGCGAGCTGCCGAAACACGATCATGCGCAGGTCGACGGGCTCGATGCGCCCGCGCCGTCGACGCCC
GTTCCGCAAGGAGTGCAGTC

Downstream 100 bases:

>100_bases
CGCATCTTACGTGCGCGCCAGAGCGGCCGGTGCGGCGGCCGCCGTCTAGATCGGCCAGCTGATCTCGAAGCGCGCGCCGC
CGAGCTCGAGCGGATCGACG

Product: TRAP-type C4-dicarboxylate transport system large permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MSQSQPLAAPAVGNPRVTRVIFGIVVVLLGALLVGFGKSAFIFCLLIGLLLTGMPVSIALGLTVLTYLFTMTAVPIESVA
LKLFTGIENFEIMAIPFFILAGGFLTHGGVARRMIAFATSIVGHMHGGLGLAGVLACAMFAAISGSSPATVMAIGSILLP
AMVRQGFPNRFGAGVIATSGSLGILIPPSIVMVLYSVSTNTSVGDLFLAGVVPGILLALLLGFVTWFIARRNGYPRFREF
DGHGPLAATGHALWGLLLCVAFSVVPPAVLIGLLYLLLRAAAPGLAAGIGLIGVAVALAWLYVAYRVGRRFTHPTLLRAE
AQRVWTTYWESVWGLLLIVVVMGGIYSGVFTPTEAAAMSAVYAFLVSTCVYGDLPLRRVPKVLLDSASMSAMLLYIITNA
VLFSFLMTSENIPQQMASWILDQGLGPIGFLLVVNVLLLMAGNVMEPSSIVLIMAPILFPVARQLGIDPIHFGILMVVNM
EVGMCHPPVGLNLYVASGITRMGITELTVAVAPWLAAMLGFLLLVTYVPAISLWLPGLMR

Sequences:

>Translated_540_residues
MSQSQPLAAPAVGNPRVTRVIFGIVVVLLGALLVGFGKSAFIFCLLIGLLLTGMPVSIALGLTVLTYLFTMTAVPIESVA
LKLFTGIENFEIMAIPFFILAGGFLTHGGVARRMIAFATSIVGHMHGGLGLAGVLACAMFAAISGSSPATVMAIGSILLP
AMVRQGFPNRFGAGVIATSGSLGILIPPSIVMVLYSVSTNTSVGDLFLAGVVPGILLALLLGFVTWFIARRNGYPRFREF
DGHGPLAATGHALWGLLLCVAFSVVPPAVLIGLLYLLLRAAAPGLAAGIGLIGVAVALAWLYVAYRVGRRFTHPTLLRAE
AQRVWTTYWESVWGLLLIVVVMGGIYSGVFTPTEAAAMSAVYAFLVSTCVYGDLPLRRVPKVLLDSASMSAMLLYIITNA
VLFSFLMTSENIPQQMASWILDQGLGPIGFLLVVNVLLLMAGNVMEPSSIVLIMAPILFPVARQLGIDPIHFGILMVVNM
EVGMCHPPVGLNLYVASGITRMGITELTVAVAPWLAAMLGFLLLVTYVPAISLWLPGLMR
>Mature_539_residues
SQSQPLAAPAVGNPRVTRVIFGIVVVLLGALLVGFGKSAFIFCLLIGLLLTGMPVSIALGLTVLTYLFTMTAVPIESVAL
KLFTGIENFEIMAIPFFILAGGFLTHGGVARRMIAFATSIVGHMHGGLGLAGVLACAMFAAISGSSPATVMAIGSILLPA
MVRQGFPNRFGAGVIATSGSLGILIPPSIVMVLYSVSTNTSVGDLFLAGVVPGILLALLLGFVTWFIARRNGYPRFREFD
GHGPLAATGHALWGLLLCVAFSVVPPAVLIGLLYLLLRAAAPGLAAGIGLIGVAVALAWLYVAYRVGRRFTHPTLLRAEA
QRVWTTYWESVWGLLLIVVVMGGIYSGVFTPTEAAAMSAVYAFLVSTCVYGDLPLRRVPKVLLDSASMSAMLLYIITNAV
LFSFLMTSENIPQQMASWILDQGLGPIGFLLVVNVLLLMAGNVMEPSSIVLIMAPILFPVARQLGIDPIHFGILMVVNME
VGMCHPPVGLNLYVASGITRMGITELTVAVAPWLAAMLGFLLLVTYVPAISLWLPGLMR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system yiaMNO involved in the uptake of 2,3- diketo-L-gulonate [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=476, Percent_Identity=28.3613445378151, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM [H]

EC number: NA

Molecular weight: Translated: 57068; Mature: 56937

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSQPLAAPAVGNPRVTRVIFGIVVVLLGALLVGFGKSAFIFCLLIGLLLTGMPVSIAL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
GLTVLTYLFTMTAVPIESVALKLFTGIENFEIMAIPFFILAGGFLTHGGVARRMIAFATS
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHCCHHHHHHHHHHHH
IVGHMHGGLGLAGVLACAMFAAISGSSPATVMAIGSILLPAMVRQGFPNRFGAGVIATSG
HHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECC
SLGILIPPSIVMVLYSVSTNTSVGDLFLAGVVPGILLALLLGFVTWFIARRNGYPRFREF
CCEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DGHGPLAATGHALWGLLLCVAFSVVPPAVLIGLLYLLLRAAAPGLAAGIGLIGVAVALAW
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LYVAYRVGRRFTHPTLLRAEAQRVWTTYWESVWGLLLIVVVMGGIYSGVFTPTEAAAMSA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VYAFLVSTCVYGDLPLRRVPKVLLDSASMSAMLLYIITNAVLFSFLMTSENIPQQMASWI
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LDQGLGPIGFLLVVNVLLLMAGNVMEPSSIVLIMAPILFPVARQLGIDPIHFGILMVVNM
HHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEC
EVGMCHPPVGLNLYVASGITRMGITELTVAVAPWLAAMLGFLLLVTYVPAISLWLPGLMR
CCCCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQSQPLAAPAVGNPRVTRVIFGIVVVLLGALLVGFGKSAFIFCLLIGLLLTGMPVSIAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
GLTVLTYLFTMTAVPIESVALKLFTGIENFEIMAIPFFILAGGFLTHGGVARRMIAFATS
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHCCHHHHHHHHHHHH
IVGHMHGGLGLAGVLACAMFAAISGSSPATVMAIGSILLPAMVRQGFPNRFGAGVIATSG
HHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECC
SLGILIPPSIVMVLYSVSTNTSVGDLFLAGVVPGILLALLLGFVTWFIARRNGYPRFREF
CCEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DGHGPLAATGHALWGLLLCVAFSVVPPAVLIGLLYLLLRAAAPGLAAGIGLIGVAVALAW
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LYVAYRVGRRFTHPTLLRAEAQRVWTTYWESVWGLLLIVVVMGGIYSGVFTPTEAAAMSA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VYAFLVSTCVYGDLPLRRVPKVLLDSASMSAMLLYIITNAVLFSFLMTSENIPQQMASWI
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LDQGLGPIGFLLVVNVLLLMAGNVMEPSSIVLIMAPILFPVARQLGIDPIHFGILMVVNM
HHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEC
EVGMCHPPVGLNLYVASGITRMGITELTVAVAPWLAAMLGFLLLVTYVPAISLWLPGLMR
CCCCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]