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The map label for this gene is ybiC [H]

Identifier: 189353569

GI number: 189353569

Start: 1818140

End: 1819249

Strand: Reverse

Name: ybiC [H]

Synonym: BMULJ_04813

Alternate gene names: 189353569

Gene position: 1819249-1818140 (Counterclockwise)

Preceding gene: 189353570

Following gene: 189353568

Centisome position: 73.56

GC content: 71.26

Gene sequence:

>1110_bases
ATGACCGTGCCGCCGACTGCCGATACCGACCTGCTGCGCATGGGCGCCGATCCGCTGCATGCGTTCGTCGCCGCGCTGTG
GGAGCGGGCCGGCAGTCACGCACGCGAAGCGCGGCTCGTCACCGATCATCTGGTCGGCGCGAATCTCGCGGGCCACGATT
CGCACGGGATCGGCATGATCCCGAACTACGTGGCGGCGTGGCGCGAAGGCGGACTGCGCCTGAACGGCCATGCCTCGATC
GTGCGCGACGGCGGCGCCGTGCTGACGATCGACGGCGGACGCGGCTTCGGCCAGGTCGTCGCGTTCGAGGCGATGGTCGA
AGGCATCGAGCGCGCGCGGCGCATCGGCATCTGCGCGATCGGCCTGCGCGACGTTCATCATCTCGGCCGGATCGGCCACT
GGGCCGAGCAGTGCGCGCGTGCGGGCCTCGTATCGTTTCACTTCGTCAACGTGCCGGGCGATCTGCTCGTCGCGCCGCTG
CACGGCACCGATGCGCGCTTCGGCACGAATCCGTTCTGCGCCGCGTATCCGCGTGCCGGCAAGCCGCCGCTGCTGCTCGA
CTTCGCGACGAGCGCGATCGCGTACGGCAAGACGCGTGTTGCGTACAACCAGGGCCGGCGCGTGCCGGCCGGTTCGCTGA
TCGACCATCGCGGACAGCCGACCGACGATCCGGCCGTGATGCACGTGCCGCCGTTCGGCGCGCTGCTGCCGTTCGGCCTG
CACAAGGGCTATGCGCTCGCGGCGATGTGCGAGCTCTTCGGCGGCGCGCTGGTGGGCGGGCATACGACGTACGCCGACAC
CGTGCAGAAGACGAGCGCGATCGTCAACGGCATGCTGTCGGTGCTGATCGACCCCAACGCATTCGATGCGGCCGATGCCG
CGCGCGAAGCCGATGCGTTCGTCGAGTGGGCGAAGGCGTCGCCGCCGGCCGGCGACGAGCCCGTGCGCATGCCCGGCGAA
CCCGAGGAAGCGAGCCGCGCCGCGCGAACGGCGGGCGGCATTCCGGTCGACCGCGCGACGTGGCGGCAGATCCGCGACAG
CGCGGCCGCGGTCGGCTTCGAAGAAGCGGAGCTCGACGCGTGGACGCAGCGCTGCTGCGTCGGCGCCTGA

Upstream 100 bases:

>100_bases
TCCGCGCGCTGATGCGCGCGCGGCGGCTCGAGCGTCGGGCCGCCGCCGTCTGCCGTTCGATTCGTTTCATTCAATCCCCT
CGTCCCGACGGAGACGCCCG

Downstream 100 bases:

>100_bases
GCGCGCACACGCGATGAGCTGGCAGGCGGAGAAGGCGCGCGGCGACGAGATCGCGTATCAGTTGTCGGGTTTCGGCGCGG
TGACGGTCACGCGATTGTTC

Product: hypothetical protein

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MTVPPTADTDLLRMGADPLHAFVAALWERAGSHAREARLVTDHLVGANLAGHDSHGIGMIPNYVAAWREGGLRLNGHASI
VRDGGAVLTIDGGRGFGQVVAFEAMVEGIERARRIGICAIGLRDVHHLGRIGHWAEQCARAGLVSFHFVNVPGDLLVAPL
HGTDARFGTNPFCAAYPRAGKPPLLLDFATSAIAYGKTRVAYNQGRRVPAGSLIDHRGQPTDDPAVMHVPPFGALLPFGL
HKGYALAAMCELFGGALVGGHTTYADTVQKTSAIVNGMLSVLIDPNAFDAADAAREADAFVEWAKASPPAGDEPVRMPGE
PEEASRAARTAGGIPVDRATWRQIRDSAAAVGFEEAELDAWTQRCCVGA

Sequences:

>Translated_369_residues
MTVPPTADTDLLRMGADPLHAFVAALWERAGSHAREARLVTDHLVGANLAGHDSHGIGMIPNYVAAWREGGLRLNGHASI
VRDGGAVLTIDGGRGFGQVVAFEAMVEGIERARRIGICAIGLRDVHHLGRIGHWAEQCARAGLVSFHFVNVPGDLLVAPL
HGTDARFGTNPFCAAYPRAGKPPLLLDFATSAIAYGKTRVAYNQGRRVPAGSLIDHRGQPTDDPAVMHVPPFGALLPFGL
HKGYALAAMCELFGGALVGGHTTYADTVQKTSAIVNGMLSVLIDPNAFDAADAAREADAFVEWAKASPPAGDEPVRMPGE
PEEASRAARTAGGIPVDRATWRQIRDSAAAVGFEEAELDAWTQRCCVGA
>Mature_368_residues
TVPPTADTDLLRMGADPLHAFVAALWERAGSHAREARLVTDHLVGANLAGHDSHGIGMIPNYVAAWREGGLRLNGHASIV
RDGGAVLTIDGGRGFGQVVAFEAMVEGIERARRIGICAIGLRDVHHLGRIGHWAEQCARAGLVSFHFVNVPGDLLVAPLH
GTDARFGTNPFCAAYPRAGKPPLLLDFATSAIAYGKTRVAYNQGRRVPAGSLIDHRGQPTDDPAVMHVPPFGALLPFGLH
KGYALAAMCELFGGALVGGHTTYADTVQKTSAIVNGMLSVLIDPNAFDAADAAREADAFVEWAKASPPAGDEPVRMPGEP
EEASRAARTAGGIPVDRATWRQIRDSAAAVGFEEAELDAWTQRCCVGA

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=353, Percent_Identity=54.6742209631728, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1786727, Length=351, Percent_Identity=26.7806267806268, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790000, Length=300, Percent_Identity=24.3333333333333, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17507179, Length=355, Percent_Identity=27.3239436619718, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17536633, Length=355, Percent_Identity=27.3239436619718, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI45553211, Length=306, Percent_Identity=29.4117647058824, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667912, Length=306, Percent_Identity=29.4117647058824, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667908, Length=306, Percent_Identity=29.4117647058824, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667904, Length=306, Percent_Identity=29.4117647058824, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24658010, Length=317, Percent_Identity=25.2365930599369, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648360, Length=345, Percent_Identity=24.9275362318841, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 38950; Mature: 38818

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPPTADTDLLRMGADPLHAFVAALWERAGSHAREARLVTDHLVGANLAGHDSHGIGMI
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PNYVAAWREGGLRLNGHASIVRDGGAVLTIDGGRGFGQVVAFEAMVEGIERARRIGICAI
HHHHHHHHCCCEEECCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEE
GLRDVHHLGRIGHWAEQCARAGLVSFHFVNVPGDLLVAPLHGTDARFGTNPFCAAYPRAG
CHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCCC
KPPLLLDFATSAIAYGKTRVAYNQGRRVPAGSLIDHRGQPTDDPAVMHVPPFGALLPFGL
CCCEEEEHHHHHHHHCCCEEEHHCCCCCCCCCHHHCCCCCCCCCEEEEECCCHHHHHHHH
HKGYALAAMCELFGGALVGGHTTYADTVQKTSAIVNGMLSVLIDPNAFDAADAAREADAF
CCCHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHH
VEWAKASPPAGDEPVRMPGEPEEASRAARTAGGIPVDRATWRQIRDSAAAVGFEEAELDA
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
WTQRCCVGA
HHHHHHCCC
>Mature Secondary Structure 
TVPPTADTDLLRMGADPLHAFVAALWERAGSHAREARLVTDHLVGANLAGHDSHGIGMI
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PNYVAAWREGGLRLNGHASIVRDGGAVLTIDGGRGFGQVVAFEAMVEGIERARRIGICAI
HHHHHHHHCCCEEECCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEE
GLRDVHHLGRIGHWAEQCARAGLVSFHFVNVPGDLLVAPLHGTDARFGTNPFCAAYPRAG
CHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCCC
KPPLLLDFATSAIAYGKTRVAYNQGRRVPAGSLIDHRGQPTDDPAVMHVPPFGALLPFGL
CCCEEEEHHHHHHHHCCCEEEHHCCCCCCCCCHHHCCCCCCCCCEEEEECCCHHHHHHHH
HKGYALAAMCELFGGALVGGHTTYADTVQKTSAIVNGMLSVLIDPNAFDAADAAREADAF
CCCHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHH
VEWAKASPPAGDEPVRMPGEPEEASRAARTAGGIPVDRATWRQIRDSAAAVGFEEAELDA
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
WTQRCCVGA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]