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The map label for this gene is glnA [H]

Identifier: 189353553

GI number: 189353553

Start: 1791008

End: 1792354

Strand: Reverse

Name: glnA [H]

Synonym: BMULJ_04797

Alternate gene names: 189353553

Gene position: 1792354-1791008 (Counterclockwise)

Preceding gene: 189353554

Following gene: 189353550

Centisome position: 72.47

GC content: 67.48

Gene sequence:

>1347_bases
ATGGCAGACGTGGTCCCCGCACTGGTCGATGAAGTCCGCGCATTCCGGCGTGCGCATCCCGAGATCCGTTACGTCGATCT
GATCAGCGTCGATCTGCCCGGGCATTTCTACGGCAAGCGCTATCCGATCGACGCGCTCGAAAAGGTCGCGGCCGGCGCGC
TGCTGAAGCTGCCGCAGAACTGCATACTGCTCGGCACGCAAGGCGGCCTGTACCGGATCGGCGATTACTGCTTCAACGAC
GGCGATCCCGATGCGCCGCGCCGGCTGATCCCCGGCACGCTGAAGCCGGTGCGCTGGGAGCGGCGGCCGCTCGCGCAGAT
GCTCATCAGCTCCGACGGCACCGCATCGCCGATCGAATTCGAGCCGCGTGAAGTGCTCGCGCGCGTGCTGCGGCGCTTCG
CGGCGCGCGGCATCCGGCCCGTCGTCGCGTTCGAGCTCGAGTTCTATCTGTTCGCCGCGCAGCTCGAGGACGGCATGCCG
CAGTACCCGCGCGATCGGCTCAGCGACGATCGCGACGATCAGCCGAACATGCATATCGAGCGGCTGTCGCGGTTTTCCGA
CGTCCTGCACGAGATGGTCGACGCCGCGCGCGAGCAGGGCATCGACGCGACGGTGATCACGGCCGAGCTCGGGCCCGGCC
AGTTCGAGATCAACTTCGGGCATACCGACGATGCGCTGCGTGCGGCCGACTGGTCGGCGCTGTTCTGCCGCAGCACGCGC
GGCGTCGCGCTGCGTCACGGCTATCGCGCGAGCTTCATGGGCAAGCCGTATCTGCATGCACCGGGCAGCGGGATGCACGT
GCACGTGAGCCTGTACGACGCCGACGGCCGCAACCTGCTCGCCGAGGATGCGCAGCGGCCGCTGCGCCACGCGGTGGCCG
GCTGTCTCGCGTTGCTGCCGCACTGCATGCCGATCTTCGCGCCGAATCACAACGCGTTCCGCCGTTACGGCTCGATGGTG
AACGCGGCGAGCCGCGCCAGCTGGGGCTTCGAGGATCGCGATGCGTGTCTGCGGATTCCCGAGTCGGACGCGCGCAACCT
GCGGATCGAACATCGGCTCGCAAGCGCGGACGCGAATCCATATCTGGTGCTCGCGGCGATCCTGACCGGGATCGAGCATG
GGCTCGACGCGGGCGTGGAGCCGATTGCGCCGCTCAACGACGATCGCGGCAGCGGCATCGATTTCCCGAAGGAGATGCTG
TCGGCCGTCGCGGCAATGCAGTCGCACGCGGCGGTGCGCGACGGGCTCGGCAGCGAGTTCGTGATGGTGTATTGCGAGCA
CAAGCGGCAGGAGGAGCTCGATTTTCGCAACGAGATCGGTGCGCGCGAGTATCGGTGGTTTCTGTGA

Upstream 100 bases:

>100_bases
CGCGTGATCTGGGTCTTCACCTAAGCCGTTACGCGGTGCCGCATCGTGCACGAATCCGGCCGACGCGCTGCGCGGCCGTC
ATACCGAACGAGGATGAGAG

Downstream 100 bases:

>100_bases
CGATGCGCGAGCGGCGGTACGGCAAGCCGCGTCGCGTTACGGCCGGGACGGCAGCGCTTCGGCCTCGGCCCAGCGCTTGA
ACGAATCGAGACGCCGGCGC

Product: glutamine synthetase

Products: NA

Alternate protein names: Gamma-Glu-Put synthetase; Glutamate--putrescine ligase [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MADVVPALVDEVRAFRRAHPEIRYVDLISVDLPGHFYGKRYPIDALEKVAAGALLKLPQNCILLGTQGGLYRIGDYCFND
GDPDAPRRLIPGTLKPVRWERRPLAQMLISSDGTASPIEFEPREVLARVLRRFAARGIRPVVAFELEFYLFAAQLEDGMP
QYPRDRLSDDRDDQPNMHIERLSRFSDVLHEMVDAAREQGIDATVITAELGPGQFEINFGHTDDALRAADWSALFCRSTR
GVALRHGYRASFMGKPYLHAPGSGMHVHVSLYDADGRNLLAEDAQRPLRHAVAGCLALLPHCMPIFAPNHNAFRRYGSMV
NAASRASWGFEDRDACLRIPESDARNLRIEHRLASADANPYLVLAAILTGIEHGLDAGVEPIAPLNDDRGSGIDFPKEML
SAVAAMQSHAAVRDGLGSEFVMVYCEHKRQEELDFRNEIGAREYRWFL

Sequences:

>Translated_448_residues
MADVVPALVDEVRAFRRAHPEIRYVDLISVDLPGHFYGKRYPIDALEKVAAGALLKLPQNCILLGTQGGLYRIGDYCFND
GDPDAPRRLIPGTLKPVRWERRPLAQMLISSDGTASPIEFEPREVLARVLRRFAARGIRPVVAFELEFYLFAAQLEDGMP
QYPRDRLSDDRDDQPNMHIERLSRFSDVLHEMVDAAREQGIDATVITAELGPGQFEINFGHTDDALRAADWSALFCRSTR
GVALRHGYRASFMGKPYLHAPGSGMHVHVSLYDADGRNLLAEDAQRPLRHAVAGCLALLPHCMPIFAPNHNAFRRYGSMV
NAASRASWGFEDRDACLRIPESDARNLRIEHRLASADANPYLVLAAILTGIEHGLDAGVEPIAPLNDDRGSGIDFPKEML
SAVAAMQSHAAVRDGLGSEFVMVYCEHKRQEELDFRNEIGAREYRWFL
>Mature_447_residues
ADVVPALVDEVRAFRRAHPEIRYVDLISVDLPGHFYGKRYPIDALEKVAAGALLKLPQNCILLGTQGGLYRIGDYCFNDG
DPDAPRRLIPGTLKPVRWERRPLAQMLISSDGTASPIEFEPREVLARVLRRFAARGIRPVVAFELEFYLFAAQLEDGMPQ
YPRDRLSDDRDDQPNMHIERLSRFSDVLHEMVDAAREQGIDATVITAELGPGQFEINFGHTDDALRAADWSALFCRSTRG
VALRHGYRASFMGKPYLHAPGSGMHVHVSLYDADGRNLLAEDAQRPLRHAVAGCLALLPHCMPIFAPNHNAFRRYGSMVN
AASRASWGFEDRDACLRIPESDARNLRIEHRLASADANPYLVLAAILTGIEHGLDAGVEPIAPLNDDRGSGIDFPKEMLS
AVAAMQSHAAVRDGLGSEFVMVYCEHKRQEELDFRNEIGAREYRWFL

Specific function: Involved in the breakdown of putrescine via the biosynthesis of gamma-L-glutamylputrescine [H]

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=462, Percent_Identity=24.025974025974, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI87081870, Length=454, Percent_Identity=37.2246696035242, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1790301, Length=160, Percent_Identity=33.125, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C [H]

EC number: =6.3.1.11 [H]

Molecular weight: Translated: 50067; Mature: 49935

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVVPALVDEVRAFRRAHPEIRYVDLISVDLPGHFYGKRYPIDALEKVAAGALLKLPQN
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCC
CILLGTQGGLYRIGDYCFNDGDPDAPRRLIPGTLKPVRWERRPLAQMLISSDGTASPIEF
EEEEECCCCCEEECHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
EPREVLARVLRRFAARGIRPVVAFELEFYLFAAQLEDGMPQYPRDRLSDDRDDQPNMHIE
CHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHH
RLSRFSDVLHEMVDAAREQGIDATVITAELGPGQFEINFGHTDDALRAADWSALFCRSTR
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCHHHHCCCHHHHHCCCC
GVALRHGYRASFMGKPYLHAPGSGMHVHVSLYDADGRNLLAEDAQRPLRHAVAGCLALLP
CEEECCCCCCCCCCCCCEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
HCMPIFAPNHNAFRRYGSMVNAASRASWGFEDRDACLRIPESDARNLRIEHRLASADANP
HHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCEEEEHHHHCCCCCC
YLVLAAILTGIEHGLDAGVEPIAPLNDDRGSGIDFPKEMLSAVAAMQSHAAVRDGLGSEF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
VMVYCEHKRQEELDFRNEIGAREYRWFL
EEEEECCCCHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure 
ADVVPALVDEVRAFRRAHPEIRYVDLISVDLPGHFYGKRYPIDALEKVAAGALLKLPQN
CCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCC
CILLGTQGGLYRIGDYCFNDGDPDAPRRLIPGTLKPVRWERRPLAQMLISSDGTASPIEF
EEEEECCCCCEEECHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
EPREVLARVLRRFAARGIRPVVAFELEFYLFAAQLEDGMPQYPRDRLSDDRDDQPNMHIE
CHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHH
RLSRFSDVLHEMVDAAREQGIDATVITAELGPGQFEINFGHTDDALRAADWSALFCRSTR
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCHHHHCCCHHHHHCCCC
GVALRHGYRASFMGKPYLHAPGSGMHVHVSLYDADGRNLLAEDAQRPLRHAVAGCLALLP
CEEECCCCCCCCCCCCCEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
HCMPIFAPNHNAFRRYGSMVNAASRASWGFEDRDACLRIPESDARNLRIEHRLASADANP
HHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCEEEEHHHHCCCCCC
YLVLAAILTGIEHGLDAGVEPIAPLNDDRGSGIDFPKEMLSAVAAMQSHAAVRDGLGSEF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
VMVYCEHKRQEELDFRNEIGAREYRWFL
EEEEECCCCHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]