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The map label for this gene is lrhA [H]

Identifier: 189353465

GI number: 189353465

Start: 1684404

End: 1685279

Strand: Reverse

Name: lrhA [H]

Synonym: BMULJ_04709

Alternate gene names: 189353465

Gene position: 1685279-1684404 (Counterclockwise)

Preceding gene: 189353467

Following gene: 189353463

Centisome position: 68.14

GC content: 71.0

Gene sequence:

>876_bases
ATGCGCGGTTTCGATCTGGATCAGCTGCGCACGTTCGCGGCCGTCGCGGACGCCGGCAGCCTGACGGCCGCCGCGCCGCT
GCTGCATCTGTCGCAGTCGACGGTCAGCGAGCAGGTGCGCAAGCTCGAGTCGCGGGCGGGCGTGCCGCTGTTCGTGCGCA
GCAAGCGCGGCGTCGAGCCGACGCCGGCCGGTGCGCGGCTGCTGCATCACGCGCGGCGCATCGTGGCGCTGAACGAGGCG
GCATTCGACGAGTTGCGCGGCCAGGCGATCAAGGGCGAGCTGCGCGTCGCGATCACCGATTACTACCGCACGCACGAAGT
CGCGGGCATGCTCGCGCGGCTGCGCGAGTGCTACCCGCAGCTGAGCCTGCACGTGAGCGCGATGAAGAGCGCCGATATCG
AGGCCGCGTATGCGAAAGGGCAGATCGATCTCGGGGTCGTGATGCACCTGTCGAGCGGACCGTTTCGGCCCGCGTCGGCC
GATACGCGCTGGGTGTTGCGGCGCGAGCCGCTGTCGTGGGTGACGTCGCCGGCACTCGCCGAGCAGTTGCCCGAACGGTT
GCCGCTCGTGCTGCTGCCGGACGACTGCATGATGCATCAGATCGCGGTGCGCTCACTCGACGAGCAGCGCATCCCGTACG
AGCTCGTGCATAGCGCGTCCGGCGTCGCGGGGCTGCAGTCGATGCTTGCGGCGGGGCTCGGCGTCGGCTGCCTGTGCGCG
TCGGCGATCGGCGACGGGCTGATGCGGCTCGGCGGCGCGAAGTACCGGCTGCCGGCGCTGCCCGACGCGGTGTTCTCGCT
GACGCCGCCGATGCCGGGCGAGCGCGAAACGGTCACGCAGGCGCGCGAGGTGCTGTCGCGGCAGTTGCTGGTGTGA

Upstream 100 bases:

>100_bases
CAAGCGGCCGTCGAGCGGACATTGTGCGCATCGTCGATGATTCGGAAAAGCGGGAAATGGTGGTAGTATCCATCGCGTTA
TCCGATGGACGGGGGATTCG

Downstream 100 bases:

>100_bases
CATCGTGGTGCGCGGTGCGTCCGCTGCGCATGCGCGGCCGGCACGAACACGCACGAACGACGCGAACGCGAAGCCGTAGC
GCAGCGATTACAGCGGGCAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRGFDLDQLRTFAAVADAGSLTAAAPLLHLSQSTVSEQVRKLESRAGVPLFVRSKRGVEPTPAGARLLHHARRIVALNEA
AFDELRGQAIKGELRVAITDYYRTHEVAGMLARLRECYPQLSLHVSAMKSADIEAAYAKGQIDLGVVMHLSSGPFRPASA
DTRWVLRREPLSWVTSPALAEQLPERLPLVLLPDDCMMHQIAVRSLDEQRIPYELVHSASGVAGLQSMLAAGLGVGCLCA
SAIGDGLMRLGGAKYRLPALPDAVFSLTPPMPGERETVTQAREVLSRQLLV

Sequences:

>Translated_291_residues
MRGFDLDQLRTFAAVADAGSLTAAAPLLHLSQSTVSEQVRKLESRAGVPLFVRSKRGVEPTPAGARLLHHARRIVALNEA
AFDELRGQAIKGELRVAITDYYRTHEVAGMLARLRECYPQLSLHVSAMKSADIEAAYAKGQIDLGVVMHLSSGPFRPASA
DTRWVLRREPLSWVTSPALAEQLPERLPLVLLPDDCMMHQIAVRSLDEQRIPYELVHSASGVAGLQSMLAAGLGVGCLCA
SAIGDGLMRLGGAKYRLPALPDAVFSLTPPMPGERETVTQAREVLSRQLLV
>Mature_291_residues
MRGFDLDQLRTFAAVADAGSLTAAAPLLHLSQSTVSEQVRKLESRAGVPLFVRSKRGVEPTPAGARLLHHARRIVALNEA
AFDELRGQAIKGELRVAITDYYRTHEVAGMLARLRECYPQLSLHVSAMKSADIEAAYAKGQIDLGVVMHLSSGPFRPASA
DTRWVLRREPLSWVTSPALAEQLPERLPLVLLPDDCMMHQIAVRSLDEQRIPYELVHSASGVAGLQSMLAAGLGVGCLCA
SAIGDGLMRLGGAKYRLPALPDAVFSLTPPMPGERETVTQAREVLSRQLLV

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=265, Percent_Identity=32.8301886792453, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI157672245, Length=143, Percent_Identity=32.8671328671329, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786713, Length=263, Percent_Identity=29.6577946768061, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=26.7206477732794, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787806, Length=165, Percent_Identity=28.4848484848485, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788887, Length=155, Percent_Identity=34.8387096774194, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789204, Length=257, Percent_Identity=27.6264591439689, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788481, Length=245, Percent_Identity=27.7551020408163, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=150, Percent_Identity=32, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=141, Percent_Identity=29.7872340425532, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081904, Length=143, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788748, Length=148, Percent_Identity=31.7567567567568, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31529; Mature: 31529

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFDLDQLRTFAAVADAGSLTAAAPLLHLSQSTVSEQVRKLESRAGVPLFVRSKRGVEP
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
TPAGARLLHHARRIVALNEAAFDELRGQAIKGELRVAITDYYRTHEVAGMLARLRECYPQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
LSLHVSAMKSADIEAAYAKGQIDLGVVMHLSSGPFRPASADTRWVLRREPLSWVTSPALA
HHHHHHHHHCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCHHHHCCHHHH
EQLPERLPLVLLPDDCMMHQIAVRSLDEQRIPYELVHSASGVAGLQSMLAAGLGVGCLCA
HHHHHHCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHH
SAIGDGLMRLGGAKYRLPALPDAVFSLTPPMPGERETVTQAREVLSRQLLV
HHHHHHHHHHCCCCEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRGFDLDQLRTFAAVADAGSLTAAAPLLHLSQSTVSEQVRKLESRAGVPLFVRSKRGVEP
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
TPAGARLLHHARRIVALNEAAFDELRGQAIKGELRVAITDYYRTHEVAGMLARLRECYPQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
LSLHVSAMKSADIEAAYAKGQIDLGVVMHLSSGPFRPASADTRWVLRREPLSWVTSPALA
HHHHHHHHHCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCHHHHCCHHHH
EQLPERLPLVLLPDDCMMHQIAVRSLDEQRIPYELVHSASGVAGLQSMLAAGLGVGCLCA
HHHHHHCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHH
SAIGDGLMRLGGAKYRLPALPDAVFSLTPPMPGERETVTQAREVLSRQLLV
HHHHHHHHHHCCCCEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]