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The map label for this gene is ribA [H]

Identifier: 189353317

GI number: 189353317

Start: 1555157

End: 1555807

Strand: Reverse

Name: ribA [H]

Synonym: BMULJ_04557

Alternate gene names: 189353317

Gene position: 1555807-1555157 (Counterclockwise)

Preceding gene: 189353319

Following gene: 189353315

Centisome position: 62.91

GC content: 64.06

Gene sequence:

>651_bases
ATGATGTCTTCGCGTCCCCAATCGCCCGCGCCGGGCAATGGCCACGCCGACGAGTGCGTGACGCTCGTTGCCACCGCGTC
GCTGCCTACGCGCTACGGTACGTTCACGTCTTACGCGTTTCGCGTATCGGGCAGCGATGCCGAACATCTCGCGCTGGTGA
TGGGCGACGTGACCGGCGAGCAGTCCGTGCTGACGCGGCTGCATTCCGAATGCCTGACCGGCGACGTGTTCGGCTCGTAT
CGTTGCGATTGCGGCGAACAACTCGATCTGGCGTTGCGCTACGTCGCGGCCGAAGGGCGCGGCGTGCTGCTGTATCTGCG
CGGCCACGAGGGGCGCGGCATCGGCCTTAGCAACAAGATCCGCGCATATGCGCTGCAGGAGCAGGGGCGCGACACCGTCG
AGGCGAACCTTGACCTCGGGCTGCCGGACGATGCGCGCGAATACGATTCGGCCGCCGCGATTCTCCGTATGCTCGGCGTG
ACGTCGGTGCGTCTGATGAGCAACAACCCGAAGAAATTCGACACGCTCGTGAAGCACGGCATTCCCGTTTGCGAACGCGT
CGCGCTCGCGGTGCCGGTGCGCGAGGAAAATGAGCGGTATATCCGGACCAAGCAGGTGAAGTTCGGGCATTACTTCGAGG
AAAACGAGTAG

Upstream 100 bases:

>100_bases
GGCGGCACCGGCAGTCGCGTGACGTTTGCAGATTAGCGGTAAACTCCCGTCACGCACTATCCAGAAAATTCCTACATTCC
TGTTCGTTTCGATTGAATCC

Downstream 100 bases:

>100_bases
TCGAGTCGCCGCGAGGCCGGTCGCATTTTGTAAGCAGGTGACTTAAAGGGACACCAAGCGATTTCGTCGTGCCGCGATCG
CGGCGCTGGCGTTTGTGTTC

Product: GTP cyclohydrolase II

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MMSSRPQSPAPGNGHADECVTLVATASLPTRYGTFTSYAFRVSGSDAEHLALVMGDVTGEQSVLTRLHSECLTGDVFGSY
RCDCGEQLDLALRYVAAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRMLGV
TSVRLMSNNPKKFDTLVKHGIPVCERVALAVPVREENERYIRTKQVKFGHYFEENE

Sequences:

>Translated_216_residues
MMSSRPQSPAPGNGHADECVTLVATASLPTRYGTFTSYAFRVSGSDAEHLALVMGDVTGEQSVLTRLHSECLTGDVFGSY
RCDCGEQLDLALRYVAAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRMLGV
TSVRLMSNNPKKFDTLVKHGIPVCERVALAVPVREENERYIRTKQVKFGHYFEENE
>Mature_216_residues
MMSSRPQSPAPGNGHADECVTLVATASLPTRYGTFTSYAFRVSGSDAEHLALVMGDVTGEQSVLTRLHSECLTGDVFGSY
RCDCGEQLDLALRYVAAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRMLGV
TSVRLMSNNPKKFDTLVKHGIPVCERVALAVPVREENERYIRTKQVKFGHYFEENE

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=192, Percent_Identity=52.6041666666667, Blast_Score=196, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319438, Length=200, Percent_Identity=42.5, Blast_Score=128, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 23742; Mature: 23742

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSRPQSPAPGNGHADECVTLVATASLPTRYGTFTSYAFRVSGSDAEHLALVMGDVTGE
CCCCCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCH
QSVLTRLHSECLTGDVFGSYRCDCGEQLDLALRYVAAEGRGVLLYLRGHEGRGIGLSNKI
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEEEEECCCCCCCCCCCCH
RAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRMLGVTSVRLMSNNPKKFDTLVKHG
HEEEEHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHCC
IPVCERVALAVPVREENERYIRTKQVKFGHYFEENE
CCHHHHHHEECCCCCCCCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MMSSRPQSPAPGNGHADECVTLVATASLPTRYGTFTSYAFRVSGSDAEHLALVMGDVTGE
CCCCCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCH
QSVLTRLHSECLTGDVFGSYRCDCGEQLDLALRYVAAEGRGVLLYLRGHEGRGIGLSNKI
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEEEEECCCCCCCCCCCCH
RAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRMLGVTSVRLMSNNPKKFDTLVKHG
HEEEEHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHCC
IPVCERVALAVPVREENERYIRTKQVKFGHYFEENE
CCHHHHHHEECCCCCCCCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA