The gene/protein map for NC_010805 is currently unavailable.
Definition Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession NC_010805
Length 2,473,162

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The map label for this gene is fabG [H]

Identifier: 189353277

GI number: 189353277

Start: 1515324

End: 1516094

Strand: Reverse

Name: fabG [H]

Synonym: BMULJ_04517

Alternate gene names: 189353277

Gene position: 1516094-1515324 (Counterclockwise)

Preceding gene: 189353278

Following gene: 189353276

Centisome position: 61.3

GC content: 71.6

Gene sequence:

>771_bases
ATGGCTGAGCACGCACCGGTCGTGTCGCTCGCCGGGCGGCGCGTCGTCGTGACGGGCGGCGCGCGCGGCCTCGGCGCCGC
GTTCGTGACGGCGCTCGTCGACGCGGGCGCGCAAGTCGCGTTCGGCGACGTGCTCGTCGACGAAGGCCGCGCGCTCGCCA
CGTCGCTCGCGCAGCGCGGCCATGCCGCGCATTTCTTCGCGCTCGATCTCGCCGACGCGGCCAGCGTCGACGCATTCGTC
GCGCAATGCGCCGCGGCGCTCGGCGGCATCGACGGGCTGATCAACAACGCGGCGATCACGAACTCGGGCGGCAAGGCGTC
GACGGAACTCGACGTGCCGACATGGGACGCGGTGATGAACGTGAACGTGCGCGGCCTCTGGCTCGTCAGCAACGCCGCGC
TGCCGCACCTCGCGCAGTCGGGCCGCGGTGCGATCGTGAACCTCGCCTCGGATACCGCGCTGTGGGGCGCGCCGAAGCTG
CTCGCCTATGTGGCGAGCAAGGGCGCCGTGATCGCGATGACCCATGCGCAGGCGCGCGAATTCGGCGCGCACGGCGTGAC
GGTCAACGCGATCGCGCCGGGCCTCACCGAAGTCGAGGCGACCGCATACGTGCCCGCGGAGCGGCACGCGTATTACCTGC
AGGGCCGTGCGCTCACGCGTGCGCAGGTGCCGGGCGACGTGACGGGCCCCGTGCTGTTCCTGCTGTCCGACGCCGCGCGC
TTCGTGACCGGTCAACTGCTGCCTGTGAACGGCGGCTTCGTAATGAATTGA

Upstream 100 bases:

>100_bases
GGCATCACGCGCGTGCGCCGGATGCTGCGCCAGCGCGCGCAGGAACATCTGTCGGCGCTCGATGCGCATCGCGCGGCGCA
GGCTGCAGCGGAGTCCGCGC

Downstream 100 bases:

>100_bases
TGGTTTTCACTCTTTGAGGAGATGACGATGGCGGACGCCGATATCGAACGCAAATCGTGGGATCAGCCGGAAGGCGCAAC
GTTCGGCGAGTGGATGGAAG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MAEHAPVVSLAGRRVVVTGGARGLGAAFVTALVDAGAQVAFGDVLVDEGRALATSLAQRGHAAHFFALDLADAASVDAFV
AQCAAALGGIDGLINNAAITNSGGKASTELDVPTWDAVMNVNVRGLWLVSNAALPHLAQSGRGAIVNLASDTALWGAPKL
LAYVASKGAVIAMTHAQAREFGAHGVTVNAIAPGLTEVEATAYVPAERHAYYLQGRALTRAQVPGDVTGPVLFLLSDAAR
FVTGQLLPVNGGFVMN

Sequences:

>Translated_256_residues
MAEHAPVVSLAGRRVVVTGGARGLGAAFVTALVDAGAQVAFGDVLVDEGRALATSLAQRGHAAHFFALDLADAASVDAFV
AQCAAALGGIDGLINNAAITNSGGKASTELDVPTWDAVMNVNVRGLWLVSNAALPHLAQSGRGAIVNLASDTALWGAPKL
LAYVASKGAVIAMTHAQAREFGAHGVTVNAIAPGLTEVEATAYVPAERHAYYLQGRALTRAQVPGDVTGPVLFLLSDAAR
FVTGQLLPVNGGFVMN
>Mature_255_residues
AEHAPVVSLAGRRVVVTGGARGLGAAFVTALVDAGAQVAFGDVLVDEGRALATSLAQRGHAAHFFALDLADAASVDAFVA
QCAAALGGIDGLINNAAITNSGGKASTELDVPTWDAVMNVNVRGLWLVSNAALPHLAQSGRGAIVNLASDTALWGAPKLL
AYVASKGAVIAMTHAQAREFGAHGVTVNAIAPGLTEVEATAYVPAERHAYYLQGRALTRAQVPGDVTGPVLFLLSDAARF
VTGQLLPVNGGFVMN

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=27.3469387755102, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=30.3149606299213, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=32.034632034632, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI66933014, Length=195, Percent_Identity=27.1794871794872, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=29.2887029288703, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=26.9387755102041, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=30.6451612903226, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254986, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI126723750, Length=140, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=32.3232323232323, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI32455239, Length=193, Percent_Identity=30.0518134715026, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI5031765, Length=193, Percent_Identity=30.0518134715026, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=25.3658536585366, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=33.0677290836653, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=34.1269841269841, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=28.90625, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=30.2788844621514, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=28.515625, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=29.296875, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=28.9156626506024, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=30.8943089430894, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI2367175, Length=259, Percent_Identity=31.2741312741313, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=26.2948207171315, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=26.8595041322314, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787526, Length=240, Percent_Identity=27.9166666666667, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=34.6613545816733, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=30.7392996108949, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=190, Percent_Identity=36.3157894736842, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=28.968253968254, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=30.1204819277108, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.4809160305344, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=26.5384615384615, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=25.2830188679245, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=24.7967479674797, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71982365, Length=195, Percent_Identity=28.7179487179487, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=216, Percent_Identity=30.5555555555556, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=25.1908396946565, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=28.2722513089005, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=192, Percent_Identity=28.6458333333333, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=23.4615384615385, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=26.9961977186312, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=24.6153846153846, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=189, Percent_Identity=26.984126984127, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=194, Percent_Identity=24.2268041237113, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=192, Percent_Identity=26.5625, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=28.3505154639175, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=202, Percent_Identity=27.7227722772277, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=36.9047619047619, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=32.5396825396825, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=33.8645418326693, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=33.4661354581673, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=28.7449392712551, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644337, Length=202, Percent_Identity=34.6534653465347, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=30.1204819277108, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=29.2929292929293, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=28.8659793814433, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356301, Length=204, Percent_Identity=30.8823529411765, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737361, Length=208, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007236, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=28.0487804878049, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26014; Mature: 25883

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MAEHAPVVSLAGRRVVVTGGARGLGAAFVTALVDAGAQVAFGDVLVDEGRALATSLAQRG
CCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCC
HAAHFFALDLADAASVDAFVAQCAAALGGIDGLINNAAITNSGGKASTELDVPTWDAVMN
CCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCCCEEECCCCCHHEEE
VNVRGLWLVSNAALPHLAQSGRGAIVNLASDTALWGAPKLLAYVASKGAVIAMTHAQARE
CCCEEEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEEECHHHHH
FGAHGVTVNAIAPGLTEVEATAYVPAERHAYYLQGRALTRAQVPGDVTGPVLFLLSDAAR
HCCCCEEEEECCCCCCCEEEEEECCCHHCEEEEECCEEEECCCCCCCCCHHHHHHHHHHH
FVTGQLLPVNGGFVMN
HHCCEEEEECCCEEEC
>Mature Secondary Structure 
AEHAPVVSLAGRRVVVTGGARGLGAAFVTALVDAGAQVAFGDVLVDEGRALATSLAQRG
CCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCC
HAAHFFALDLADAASVDAFVAQCAAALGGIDGLINNAAITNSGGKASTELDVPTWDAVMN
CCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCCCEEECCCCCHHEEE
VNVRGLWLVSNAALPHLAQSGRGAIVNLASDTALWGAPKLLAYVASKGAVIAMTHAQARE
CCCEEEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEEECHHHHH
FGAHGVTVNAIAPGLTEVEATAYVPAERHAYYLQGRALTRAQVPGDVTGPVLFLLSDAAR
HCCCCEEEEECCCCCCCEEEEEECCCHHCEEEEECCEEEECCCCCCCCCHHHHHHHHHHH
FVTGQLLPVNGGFVMN
HHCCEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]